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  • sequence
  • These circular RNAs (circRNAs) do not retain the exon order defined by their genomic sequence and are thought to originate from non-canonical splicing of a 5′ splice site to an upstream 3′ splice site 4 . (nature.com)
  • transcriptome
  • Our understanding of transcriptome biology is undergoing a revolution that is revealing that the regulation of expression and the types and functions of RNA are far more complex than was previously thought. (thermofisher.com)
  • The remaining whole-transcriptome RiboMinus™ RNA is suitable for direct sequencing using any next-generation sequencing platforms or microarray analysis. (thermofisher.com)
  • subsequently
  • Our RiboMinus™ technology utilizes specific locked nucleic acid (LNA®) capture probes to bind ribosomal RNA and subsequently remove it from the sample via binding to streptavidin-coated Dynabeads® magnetic beads. (thermofisher.com)
  • Group I introns may also insert into the natural intron insertion site at the RNA level, and subsequently become stably integrated into the host genome. (biomedsearch.com)
  • codon
  • Experiments are presented that reveal possible contacts between 16 S ribosomal RNA and the codon-anticodon complex. (sciencemag.org)
  • These processes suggest ribosomal recognition of the codon-anticodon pair within an active site for decoding ( 4 ). (sciencemag.org)
  • The results support a model for ribosomal decoding in which A1492 and A1493 recognize the helical structure of cognate codon-anticodon complexes in the A site. (sciencemag.org)
  • role
  • However, the frequency and general role of an RNA-based mobility pathway in the spread of natural group I introns is still unclear. (biomedsearch.com)