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  • transition
  • After a constant, organism-specific number of cleavages, many metazoan embryos undergo the mid-blastula transition (MBT), which initiates extensive cell cycle remodeling. (upenn.edu)
  • transcription
  • Chapter 2 addresses how zygotic transcription and cell cycle remodeling are coordinated. (upenn.edu)
  • I show that SAC acquisition is independent of the N:C ratio and other MBT events like cell cycle elongation and zygotic transcription. (upenn.edu)
  • embryos
  • To achieve this quickly, embryos employ specialized cell cycles called cleavages that consist of continuous rounds of DNA replication and division. (upenn.edu)
  • By artificially slowing cleavage cycles in zebrafish embryos, I demonstrate that increases in transcriptional activity are independent of cell cycle elongation and embryo age. (upenn.edu)
  • crucial
  • The results indicated that IFN-λ1 plays a crucial role in inhibiting gastric carcinoma cells and provide the foundation for the use of IFN-λ1 in tumor therapy. (spandidos-publications.com)