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  • ribosome biogenesis
  • To understand the linkage between the amount of Ag-NOR proteins, ribosome biogenesis, and cell proliferation, we investigated the variability of Ag-NOR proteins in rRNA-stimulated cells maintained in G1 and in rRNA-stimulated cells entering the mitotic cycle. (semanticscholar.org)
  • The different dynamic properties of proteins involved in different steps of ribosome biogenesis imply that the nucleolar association of these proteins is due to their specific functional roles rather than simply their specific nucleolar-targeting events. (rupress.org)
  • structural
  • The PDBFlex database explores the intrinsic flexibility of protein structures by analyzing structural variations of the same protein across the archive. (rcsb.org)
  • This allows for the easy identification of regions and types of structural flexibility present in a protein of interest. (rcsb.org)
  • Our study therefore provides important clues about the chicken-or-egg dilemma associated with the central dogma of molecular biology by showing that ribosomal history is driven by the gradual structural accretion of protein and RNA structures. (nih.gov)
  • highly conserved
  • A number of highly conserved regions on both the 12S and 16S rRNA require posttranscriptional methylation by a SAM-dependent rRNA methyltransferase before they can be assembled into competent ribosomal particles ( Baer and Dubin, 1981 ). (pubmedcentralcanada.ca)
  • nucleolar components
  • Location of rRNA transcription to the nucleolar components: disappearance of the fibrillar centers in nucleoli of regenerating rat hepatocytes. (semanticscholar.org)
  • These findings suggest that the rapid exchange of nucleolar components between the nucleolus and nucleoplasm may represent a new level of regulation for rRNA synthesis. (rupress.org)
  • PMID
  • In addition to their function in the ribosome, many ribosomal proteins have some function 'outside' the ribosome [ PMID: 11290319 , PMID: 11114498 ]. (ebi.ac.uk)
  • In E. coli, the C-terminal half of L11 has been shown [ PMID: 2483975 ] to be in an extended and loosely folded conformation and is likely to be buried within the ribosomal structure. (ebi.ac.uk)
  • NCBI
  • We apply Proteinortho to compute orthologous proteins in the complete set of all 717 eubacterial genomes available at NCBI at the beginning of 2009. (biomedcentral.com)
  • 2000
  • Other techniques, such as in situ identification of uncultured bacteria and microbial community composition that target ribosomal RNA (rRNA) have been useful (Amann 2000) for studying microbial communities in wastewater systems. (environmental-expert.com)
  • complex
  • RNA-protein complex formation was proportional to the amount of proteins added to the reaction mixture. (uniprot.org)
  • We find that in the context of the TRAMP complex, the DExH core functions independently in vitro as an RNA helicase and a protein-binding platform. (pnas.org)
  • bacterial
  • We show that the normal pattern of localization of PBP1 is dependent on MreB and that the proteins can physically interact using in vivo pull-down and bacterial two-hybrid approaches. (wiley.com)
  • We identified thirty proteins present in 99% of all bacterial proteomes. (biomedcentral.com)
  • orthologous
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)
  • molecular
  • A census of domain structures in proteomes of hundreds of completely sequenced organisms is used to compose a data matrix and its transposed matrix, which are then used to build phylogenomic trees describing the evolution of individual protein structures and entire molecular repertoires, respectively. (nih.gov)
  • Embedded in the tree of rRNA substructures and tree of protein domains are timelines that assign age to molecular structures. (nih.gov)
  • Annotation
  • be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein. (uniprot.org)
  • interact
  • Most of the proteins interact with multiple RNA elements, often from different domains. (ebi.ac.uk)
  • L7/L12 is the only ribosomal protein that does not interact directly with rRNA, but instead has indirect interactions through L10. (ebi.ac.uk)
  • The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. (rcsb.org)
  • Two bean cell wall proteins more abundant during water deficit are high in proline and interact with a plasma membrane protein Plant Journal, 22, 277-288. (unam.mx)
  • vitro
  • Ancestral ribonucleoprotein components show similarities to in vitro evolved RNA replicase ribozymes and protein structures in extant replication machinery. (nih.gov)
  • Specific
  • A single fluorescently labeled primer that is specific for a microbial population and targets an interior region of both pre16S and 16S rRNA is employed. (environmental-expert.com)
  • For example, it is not clear whether specific proteins are stably associated with the nucleolus or are exchanged with the nucleoplasm. (rupress.org)
  • Assay
  • DNA samples from foliage tissues of 15 symptomatic palms were analysed by employing a nested PCR assay primed by phytoplasma universal ribosomal RNA operon primer pairs, P1/P7 followed by R16F2n/R2. (microbiologyresearch.org)