• SEPPIC designs and manufactures excipients such as emulsifiers, solubilizers and texturing agents for the topical route of administration to help formulators optimize and simplify their formulations. (seppic.com)
  • The route or course the active substance takes from application location to the location where it has its target effect is usually rather a matter of pharmacokinetics (concerning the processes of uptake, distribution, and elimination of drugs). (wikipedia.org)
  • A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. (wikipedia.org)
  • Route of administration and dosage form are aspects of drug delivery . (wikipedia.org)
  • Drug Administration Routes. (scielo.br)
  • The route of administration is defined as the path by which a drug or other substance enters the body. (wellness.com)
  • The United States Food and Drug Administration recognizes 111 distinct routes of administration. (wellness.com)
  • The development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. (wellness.com)
  • Improving drug performance and safety is key for oral route. (seppic.com)
  • Challenges of this route of administration are linked to the texture of the drug to improve patient compliance as well as efficacy. (seppic.com)
  • This newly redesigned edition describes hardcore drug-abusing populations, emerging drugs and markets, new routes of administration , use patterns, demand for treatment, drug-related criminal activity, and supply and distribution patterns from midyear 1999 to midyear 2000. (thefreedictionary.com)
  • Research examining the demographic and substance use characteristics of illicit drug use in the United States has typically failed to consider differences in routes of administration or has exclusively focused on a single route of administration-injection drug use. (rti.org)
  • Data from National Survey on Drug Use and Health were used to compare past-year injection drug users and non-injection drug users' routes of administration of those who use the three drugs most commonly injected in the United States: heroin, methamphetamine, and cocaine. (rti.org)
  • Injection drug users were more likely than those using drugs via other routes to be older (aged 35 and older), unemployed, possess less than a high school education, and reside in rural areas. (rti.org)
  • A study was conducted to quantitate tissue macromolecular adduct formation after induction of drug metabolizing enzymes or long term oral administration of 4,4'-methylenebis(2-chloroaniline) (101144) (MOCA), a model aromatic amine, in the rat. (cdc.gov)
  • As a result, experts at a previous meeting entitled "Misoprostol: An emerging technology for women's health" held at the Population Council in New York in May 2001 identified the need for consensus on the clinical importance of route and an examination of the implications of route for future research and drug development. (gynuity.org)
  • In most investigations of the relationship of venous thromboembolism and menopausal HT, the route of hormone administration has been primarily oral. (acog.org)
  • Routes of administration are generally classified by the location at which the substance is applied. (wikipedia.org)
  • All routes resulted in infection of all tissues tested. (nih.gov)
  • Antithyroid drugs, symptoms of another important recent trials showed that for route of administration of lidocaine injection patients with phenylephrine. (imagenenaccion.org)
  • A systematic literature search was carried out in MEDLINE, EMBASE, Cochrane Library and American College of Rheumatology/European League Against Rheumatism meeting abstracts, searching for randomised controlled trials evaluating various dosages or routes of administration of methotrexate in RA. (nih.gov)
  • In addition, adults could not be boosted by a second administration of virus, presumably due to the presence of high levels of neutralizing antibodies. (nih.gov)
  • Deviation from the recommended route may reduce vaccine efficacy or increase local adverse reactions. (cdc.gov)
  • The oral route presents major benefits such as the ease of use (like tablets & capsules). (seppic.com)
  • The results indicated that enzymatic induction by phenobarbital resulted in a significant increase in covalent binding of C-14 to globin after administration of C-14 labeled MOCA. (cdc.gov)