• 11. Reversal of rocuronium-induced neuromuscular block with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine. (nih.gov)
  • Refrigerated Stability of Diluted Cisatracurium, Rocuronium, and Vecur" by Kristen G. Dinsmore, Bethany Campbell et al. (etsu.edu)
  • The purpose of this study is to investigate the stored stability of dilutions of neuromuscular blocking agents (NMBAs), namely cisatracurium, rocuronium, and vecuronium, for skin prick/intradermal testing. (etsu.edu)
  • These are either aminosteroids such as rocuronium and vecuronium, or benzylisoquinoliniums such as atracurium. (anaestheasier.com)
  • Objective: The aim of the study was to investigate the effects of rocuronium, mivacurium, and atracurium on arrhythmia markers, QT interval, and QT dispersion (QTd). (cumhuriyet.edu.tr)
  • During the induction of anesthesia, muscle relaxants of 0.6 mg/kg rocuronium in Group R, 0.2 mg/kg mivacurium in Group M, and 0.5 mg/kg atracurium in Group A were employed. (cumhuriyet.edu.tr)
  • 16 mg/kg is recommended if there is a clinical need to reverse neuromuscular blockade soon (approximately 3 minutes) after administration of a single dose of 1.2 mg/kg of rocuronium. (nih.gov)
  • 1. [Efficacy of sugammadex in the reversal of neuromuscular blockade induced by rocuronium in long-duration surgery: under inhaled vs. intravenous anesthesia]. (nih.gov)
  • 4. A randomized, dose-response study of sugammadex given for the reversal of deep rocuronium- or vecuronium-induced neuromuscular blockade under sevoflurane anesthesia. (nih.gov)
  • 5. Reversal of neuromuscular blockade by sugammadex after continuous infusion of rocuronium in patients randomized to sevoflurane or propofol maintenance anesthesia. (nih.gov)
  • 14. Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points: an international, multicenter, randomized, dose-finding, safety assessor-blinded, phase II trial. (nih.gov)
  • sugammadex is a relatively new reversal drug that has a unique mechanism of action and specifically reverses a rocuronium- and vecuronium-induced neuromuscular blockade. (aneskey.com)
  • However, an approved indication for sugammadex is reversal of a profound neuromuscular blockade specifically from rocuronium or vecuronium. (aneskey.com)
  • For example, if rocuronium were given to facilitate endotracheal intubation, but the trachea could not be intubated, sugammadex could reverse a profound neuromuscular blockade. (aneskey.com)
  • We observed delayed onset of blockade and prolonged recovery following administration of 0.6 mg/kg rocuronium in a patient with dermatomyositis. (anesth-pain-med.org)
  • Here, we report a case of delayed onset of neuromuscular blockade and prolonged recovery after administration of 0.6 mg/kg rocuronium, followed by normal response to reversal after administration of pyridostigmine in a patient with DM. (anesth-pain-med.org)
  • Antagonism of neuromuscular blockade (NMB) induced by rocuronium and vecuronium can be achieved with either neostigmine or sugammadex. (archive.org)
  • As an indirect cholinergic agonist , neostigmine is mainly used postoperatively under the brand name "Bloxiverz" to reverse shallow levels of neuromuscular blockade induced by non-depolarizing muscle relaxants (e.g. rocuronium, vecuronium). (beautyfll.com)
  • General anesthesia was performed using propofol 2 mg/kg and rocuronium 0.6 mg/kg for induction, followed by sevoflurane and rocuronium 0.15 mg/kg as needed. (nih.gov)
  • 2. [Tracheal intubation quality under remifentanil-propofol with sevoflurane compared with remifentanil-propofol with rocuronium: a randomized double-blind clinical trial]. (nih.gov)
  • 3. Reversal of rocuronium-induced neuromuscular block with the novel drug sugammadex is equally effective under maintenance anesthesia with propofol or sevoflurane. (nih.gov)
  • 6. The neuromuscular effects of rocuronium under sevoflurane-remifentanil or propofol-remifentanil anesthesia: a randomized clinical comparative study in an Asian population. (nih.gov)
  • In conclusion, the results of this study support the overall favorable safety profile, inclusive of cardiac safety parameters, of sugammadex for reversal of rocuronium- or vecuronium-induced moderate and deep neuromuscular block in ASA Class 3 or 4 participants. (medscape.com)
  • 8. A case where rocuronium was unable to achieve neuromuscular block immediately after sugammadex administration. (nih.gov)
  • 9. Efficacy of sugammadex for the reversal of moderate and deep rocuronium-induced neuromuscular block in patients pretreated with intravenous magnesium: a randomized controlled trial. (nih.gov)
  • 10. Reversal of rocuronium-induced (1.2 mg/kg) profound neuromuscular block by sugammadex: a multicenter, dose-finding and safety study. (nih.gov)
  • 15. Sugammadex rapidly reverses moderate rocuronium- or vecuronium-induced neuromuscular block during sevoflurane anaesthesia: a dose-response relationship. (nih.gov)
  • 17. [Efficacy and safety of sugammadex (Org 25969) in reversing moderate neuromuscular block induced by rocuronium or vecuronium in Japanese patients]. (nih.gov)
  • 7. Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflurane anaesthesia. (nih.gov)
  • Even though it does not release histamine, rocuronium was identified as producing an increased risk for hypersensitivity reactions in France and Norway, with no confirmation from other countries. (aneskey.com)
  • General anesthesia for cesarean section using vecuronium as a component may delay the onset of lactation. (nih.gov)
  • Rocuronium bromide injection is a nondepolarizing neuromuscular blocking agent indicated as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation. (nih.gov)
  • According to the Bend Bulletin, the doctors determined Macpherson needed an intravenous anti-seizure medication called fosphenytoin, but instead accidentally administered rocuronium, which caused Macpherson to stop breathing and go into cardiac arrest, leading to irreversible brain damage. (kalicomputers.com)
  • These highlights do not include all the information needed to use ROCURONIUM BROMIDE INJECTION safely and effectively. (nih.gov)
  • See full prescribing information for ROCURONIUM BROMIDE INJECTION. (nih.gov)
  • Reduced rocuronium bromide injection activity possible: Anticonvulsants. (nih.gov)
  • Effects of High-Dose Rocuronium on the QTc Interval During Anaesthesia Induction in Patients Undergoing Coronary Artery Bypass Graft Surgery Turk J Anaesth Reanim 2014;42(5):245-50. (cumhuriyet.edu.tr)
  • Because of its rapid onset time, rocuronium is often used to facilitate tracheal intubation, but its duration of action is much longer than that of SCh. (aneskey.com)
  • All patients had skin tests, quantification of sIgE and BAT to rocuronium, together with investigations for all relevant compounds administered during anaesthesia that could have evoked the reaction. (uantwerpen.be)
  • Cross-reactivity with vecuronium was documented in 69% of the patients. (uantwerpen.be)
  • amikacin increases effects of vecuronium by pharmacodynamic synergism. (medscape.com)
  • amphotericin B deoxycholate increases effects of vecuronium by pharmacodynamic synergism. (medscape.com)
  • However, when the train-of-four ratio reached 0.3, the patient was administered pyridostigmine and glycopyrrolate, which led to normal response to reversal of rocuronium. (anesth-pain-med.org)
  • Diagnosis of rocuronium allergy was considered definite when the patient demonstrated a positive outcome for at least two of the three aforementioned tests. (uantwerpen.be)
  • As the Associated Press and other news outlets reported, the nurse allegedly injected a 75-year-old patient with the paralytic anesthetic vecuronium instead of Versed, a sedative. (kalicomputers.com)
  • Objective: To assess skin testing, quantification of specific IgE (sIgE) and flowassisted activation of basophils [basophil activation test (BAT)] in the diagnosis of rocuronium allergy. (uantwerpen.be)
  • Conclusion: Skin testing merits the status of primary diagnostic investigation to document rocuronium allergy and cannot be substituted by quantification of sIgE or BAT. (uantwerpen.be)
  • Vecuronium bromide and its advanced intermediates: A crystallographic and spectroscopic study. (nih.gov)