• synthetase
  • We report the development of a bisubstrate reagent that, similar to tyrosyl t-RNA synthetase (TyrTS), provides a surface for ATP and L -Tyr to render a pseudo-intramolecular reaction forming 5′-tyrosyl adenylate (tyrAd). (rsc.org)
  • significantly
  • Pillé and colleagues previously found that blocking RhoC expression by short interfering RNA significantly inhibited cell proliferation of breast tumor cells in vitro as well as tumor growth in an animal model ( 12 ). (aacrjournals.org)
  • Function
  • Thus, the N-terminal 45% region of colicin D, which is highly homologous to that of colicin B, is thought to function in receptor binding and membrane transfer. (pnas.org)