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  • residues
  • We have performed a novel analysis of the location of residues affected by RNA editing in proteins in plant organelles. (biomedcentral.com)
  • We suggest that RNA editing may have conferring evolutionary advantage by acting as a mechanism to reduce susceptibility to DNA damage by allowing the increase in GC content in DNA while maintaining RNA codons essential to encode residues required for protein folding and activity. (biomedcentral.com)
  • Earlier analysis [ 15 ] of the location of RNA targets within transcripts did not detect any rules to explain why particular residues within a protein sequence were affected by codon changes while other residues were not altered. (biomedcentral.com)
  • Several E. coli proteins were also reported to autophosphorylate on Ser/Thr residues, including the molecular chaperone DnaK ( 17 ), an essential GTPase termed Era ( 18 ), and the nucleotide diphosphate kinase ( 19 ). (mcponline.org)
  • kinases
  • In addition to a preliminary description of a protein kinase C-like activity ( 12 ), this organism possesses two well characterized Ser/Thr kinases: the isocitrate dehydrogenase kinase/phosphorylase ( 13 ) and the recently described YihE kinase ( 14 ). (mcponline.org)
  • contrast
  • Among them, type 2C Ser/Thr PPases constitute an evolutionarily conserved group that, in contrast to other PPase families, are monomeric enzymes apparently lacking regulatory subunits. (genetics.org)
  • Previously
  • PillĂ© and colleagues previously found that blocking RhoC expression by short interfering RNA significantly inhibited cell proliferation of breast tumor cells in vitro as well as tumor growth in an animal model ( 12 ). (aacrjournals.org)
  • sites
  • Transfer RNA is a fairly small molecule, consisting of 75-90 nucleotides, which folds over itself (via hydrogen bonding between base pairs at four different sites), forming a three-dimensional L-shaped structure. (kenyon.edu)