• The vast majority of genes are encoded with a single scheme (see the RNA codon table). (wikipedia.org)
  • Several marker substitutions, including Pro 19, Cys 32 and Lys 62, have been introduced in seminal RNase genes which made them to be recognized as different from their pancreatic cousins. (wikipedia.org)
  • The virus that most closely matched H5N1 for virulence was one with the hemagglutinin (HA), the neuraminidase (NA) and the PB1 avian flu virus RNA molecules with their genes combined with the remaining five RNA molecules (PB2, PA, NP, M, and NS) with their genes from the human flu virus. (wikipedia.org)
  • Elucidating the 16S rRNA 3′ boundaries and defining optimal SD/aSD pairing in Escherichia coli and Bacillus subtilis using RNA-Seq data. (uottawa.ca)
  • RNA-Seq-Based Analysis Reveals Heterogeneity in Mature 16S rRNA 3' Termini and Extended Anti-Shine-Dalgarno Motifs in Bacterial Species. (uottawa.ca)
  • We present an RNA-Seq based approach to map 3′ end sequences of mature 16S rRNA (3′ TAIL) in bacteria with single-base specificity. (uottawa.ca)
  • This work was based upon Ochoa's earlier studies, yielding the latter the Nobel Prize in Physiology or Medicine in 1959 for work on the enzymology of RNA synthesis. (wikipedia.org)
  • Understanding these processes at the molecular level requires homogeneous RNA samples for structural, biochemical and pharmacological studies. (nih.gov)
  • The anticodon region is where the anticodon triplet base-pairs with the codon triplet of the messenger RNA. (kenyon.edu)
  • Implications for codon-anticodon interaction and comparison with other types of RNA-RNA interacting systems are also discussed in this chapter. (asmscience.org)
  • Transfer RNA is a fairly small molecule, consisting of 75-90 nucleotides, which folds over itself (via hydrogen bonding between base pairs at four different sites), forming a three-dimensional L-shaped structure. (kenyon.edu)
  • The chapter describes two RNA loop-loop interacting systems that do not involve modified nucleotides. (asmscience.org)
  • Modulatory Role of Modified Nucleotides in RNA Loop-Loop Interaction, p 113-133. (asmscience.org)
  • We devise CAPRI, a method to map RNA-binding domains (RBDs) by simultaneous identification of RNA interacting crosslinked peptides and peptides adjacent to such crosslinked sites. (nature.com)
  • Previous RBD mapping approaches have applied mass spectrometric techniques to identify peptides covalently bound to RNA 17 . (nature.com)
  • The other elongating regions can be detected by adding antibiotics like cycloheximide that inhibit translocation, chloramphenicol that inhibits transfer of peptides within the ribosome, or non-drug means like thermal freezing. (wikipedia.org)
  • Finally, using a specific small-interfering RNA against the endogenous aquaporin AQP3, the water transport accompanying CFTR activity decreased. (biologists.org)
  • Syngeneic lymphocytes were transferred from rodents heavily immunized against the tumor to inhibit growth of small established tumors, becoming the first example of ACT. (wikipedia.org)
  • c) Conserved structural core of the N-terminal RNA-binding domain of Trm61, colored orange-red. (nih.gov)
  • This results in horizontal gene transfer between the virus and cell, resulting in the evolution of the virus and the bacterium. (wikipedia.org)
  • Administration of IL-2 after cell transfer enhanced therapeutic potential. (wikipedia.org)
  • During the lytic cycle, similar to other double-stranded phages, bacteriophage P2 applies a holin-endolysin system to lyse the host cell. (wikipedia.org)
  • The HA RNA molecule contains the HA gene, which codes for hemagglutinin, which is an antigenic glycoprotein found on the surface of the influenza viruses and is responsible for binding the virus to the cell that is being infected. (wikipedia.org)
  • A CAR therapy for cancer, using a technique called adoptive cell transfer, has been approved by the US Food and Drug Administration for use against acute lymphoblastic leukemia. (wikipedia.org)
  • Based on manual screening, we find 40 pairs of IDRs whose RNA-binding function and location is conserved between Drosophila and human orthologs. (nature.com)
  • High-throughput sequencing indicates that much of the human genome is transcribed into non-coding RNAs (ncRNAs) with estimates of the proportion varying from ~62% predicted by the ENCODE project ( 1 ) to ~10% based on evolutionary conservation ( 2 ). (frontiersin.org)
  • An unusual feature of the human MT-ND4L gene is the 7-nucleotide gene overlap of its last three codons (5'-CAA TGC TAA-3' coding for Gln, Cys and Stop) with the first three codons of the MT-ND4 gene (5'-ATG CTA AAA-3' coding for amino acids Met-Leu-Lys). (wikipedia.org)
  • Tat acts by binding to an RNA stem-loop structure, the trans-activating response element (TAR), found at the 5′ ends of nascent HIV-1 transcripts. (wikipedia.org)