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  • Proteins
  • Within the framework of living cells, ribosomes are giant assemblies composed of many different proteins (r-proteins) and long ribosomal RNA (rRNA) chains. (docme.ru)
  • We review arguments that biology emerged from a reciprocal partnership in which small ancestral oligopeptides and oligonucleotides initially both contributed rudimentary information coding and catalytic rate accelerations, and that the superior information-bearing qualities of RNA and the superior catalytic potential of proteins emerged from such complexes only with the gradual invention of the genetic code. (mdpi.com)
  • A crucial evolutionary step was the establishment of macromolecule import systems to allow the come back of proteins and RNAs into the organelle. (nih.gov)
  • synthesis
  • In some cases vaccinia viral RNA or poly(A) synthesis have been implicated in the establishment of this effect. (biomedsearch.com)
  • Following a phase of biogenesis possibly emerging directly from cosmic symmetry-breaking (King 1978 , 2004 ), based on spontaneous prebiotic RNA synthesis (Powner et. (dhushara.com)
  • 1974
  • In 1974, Carter and Kraut [ 1 ] showed by model building that the range of stable twisted conformations of extended polypeptides included a double-helical configuration that precisely complements the A form RNA double-helix ( Figure 1 ). (mdpi.com)
  • Research
  • This article is a fully referenced research review to overview progress in unraveling the details of the evolutionary Tree of Life, from life's first occurrence in the RNA-era, to humanity's emergence and diversification, through migration and intermarriage.The Tree of Life, in biological terms, has come to be identified with the evolutionary tree of biological diversity. (dhushara.com)
  • groups
  • They proposed that this complementarity, and specifically a repeating hydrogen bond between ribose 2'OH groups and outward-pointing carbonyl oxygen atoms, suggested a basis for reciprocal pre-biotic autocatalysis, in which screw dislocations between the two partners could serve, respectively, as rudimentary active-sites for catalysis of subsequent polymerization of peptides by RNA and RNA by peptides ( Figure 2 ) [ 1 , 2 ]. (mdpi.com)
  • basis
  • A coherent structural basis for that scenario was articulated nearly a decade before the demonstration of catalytic RNA. (mdpi.com)