• Alternative splicing of NQO 1 RNA could provide an important mechanism for regulating NQO 1 gene expression. (aacrjournals.org)
  • New high-throughput transcriptome sequencing technologies such as RNA-Seq and ChIP-sequencing open opportunities for incorporating additional extrinsic evidence into gene prediction and validation, and allow structurally rich and more accurate alternative to previous methods of measuring gene expression such as expressed sequence tag or DNA microarray. (wikipedia.org)
  • Scotty Scotty: a web tool for designing RNA-Seq experiments to measure differential gene expression. (wikipedia.org)
  • There are several types of RNA modifications that impact gene expression. (wikipedia.org)
  • Gene expression seems to increase in the obesity-resistant categories The promoter region for c8orf33 covers 1191 base pairs of DNA and contains over 700 potential factor binding sites. (wikipedia.org)
  • During gene expression, the DNA is first copied into RNA. (wikipedia.org)
  • Statistical tests, specifically designed to handling count based data, can be used for differential gene expression and alternative splicing analysis. (wikipedia.org)
  • 2001. Messenger RNA Splicing Signals . (umd.edu)
  • While I was searching for information on RNA structure and IRES activity so I could explain noncanonical RNA interactions and structure to you, I came across the reviews of Marilyn Kozak ( 2001 , 2001 exchange , 2005 , and 2006 ). (gnxp.com)
  • Furthermore, depletion of p68 RNA helicase arrested spliceosome assembly at the prespliceosome stage, suggesting that p68 may play a role in the transition from prespliceosome to spliceosome. (asm.org)
  • The intronsat removed from the gene traW%CWjN3 ina process knowna premRNA splicing (Reed 2000). (psu.edu)
  • Influenza A, B, and C viruses belong to the family Orthomyxoviridae and are characterized by segmented, single-stranded, negative-sense (−) RNA genomes. (beds.ac.uk)
  • Retroviral Psi packaging element is a cis-acting RNA element identified in the genomes of the retroviruses Human immunodeficiency virus (HIV) and Simian immunodeficiency virus (SIV). (wikipedia.org)
  • Her work on retroviral RNA processing has included mapping m6A modification sites in retrovirus genomes and determining a consensus sequence (RGACU). (wikipedia.org)
  • DIS is characterized by a conserved stem and palindromic loop that forms a kissing-loop complex between HIV-1 RNA genomes to dimerize them for encapsidation. (wikipedia.org)
  • A new protocol for sequencing the messenger RNA in a cell, known as RNA-Seq, generates millions of short sequence fragments in a single run. (nih.gov)
  • Splicing of messenger RNA precursors. (psu.edu)
  • 1977). "Human beta-globin messenger RNA. (wikipedia.org)
  • The tmRNA is remarkably versatile: it recycles the stalled ribosome, adds a proteolysis-inducing tag to the unfinished polypeptide, and facilitates the degradation of the aberrant messenger RNA. (wikipedia.org)
  • Polyadenylation is the addition of a poly(A) tail to a messenger RNA. (wikipedia.org)
  • For further information, see RNA and Messenger RNA RNAs are a type of large biological molecules, whose individual building blocks are called nucleotides. (wikipedia.org)
  • Bioinformatic tools predicted disruption of consensus donor or acceptor sites with high sensitivity, but cryptic site usage was predicted with low specificity, supporting the value of RNA-based assays. (nih.gov)
  • This difference suggests that acceptor sites are located first in humans and, having been located, reduce by a factor of two the number of alternative sites available as donors. (nih.gov)
  • Extensive cytological and biochemical analyses show that the conserved Sf3A2 and Prp31 splicing factors bind microtubules and the Ndc80 complex, playing direct mitotic functions in both Drosophila and human mitosis. (elifesciences.org)
  • Here we analyzed natural variation of splicing patterns in the transcriptomes of 81 natural strains of Drosophila melanogaster with known genotypes. (nih.gov)
  • Quality assessment of raw data is the first step of the bioinformatics pipeline of RNA-Seq. (wikipedia.org)
  • With the advent of Bioinformatics and widespread use of computers, several good programs now exist for the identification of cis-acting control regions that affect the splicing outcomes of a gene and advanced programs can even consider splicing outcomes in various tissue types. (wikipedia.org)
  • Especially in MeRIP-Seq, the bioinformatics tools that are currently available are only able to call 1 site per ~100-200nt wide peak, so a substantial portion of clustered m6As (~64nt between each individual site within a cluster) are missed. (wikipedia.org)