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  • yeast
  • Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. (gsf.de)
  • La also binds to 3′ extended precursors to human U1 and the yeast snRNAs ( 34 , 58 ) and to internal sequences of several viral RNAs, in some cases at sequences that lack poly(U) tracts ( 4 , 23 ). (asm.org)
  • SNORD116
  • One of these recent findings are the loss of two gene clusters encoding small nucleolar RNAs, SNORD115 and SNORD116, that contribute to Prader-Willi syndrome, the most common syndromic form of obesity in humans. (lu.se)
  • molecular
  • Stem-loop quantitative reverse transcription PCR (RT-qPCR) is a molecular technique used for identification and quantification of individual small RNAs in cells. (mdpi.com)
  • SNORA42
  • A third example, is orphan RNA SNORA42 which is frequently overexpressed in lung cancer and where high SNORA42 expression, show a significant correlation with poor survival. (lu.se)
  • Processing
  • Oligonucleotide-targeted ribonuclease H inactivation of the U3-like RNA component also abolished processing activity. (sciencemag.org)
  • In vitro study of processing of the intron-encoded U16 small nucleolar RNA in Xenopus laevis. (asm.org)
  • Little is known about the mechanism and the factors involved in this new type of processing. (asm.org)
  • motif
  • A motif within the U3 homolog is complementary to the region around the three cleavage sites in the pre-RNA substrate. (sciencemag.org)
  • Component
  • Messenger RNA (mRNA) translation and thereby gene expression depend on the cell's ability to produce vast numbers of ribosomes, the major component of the translational machinery. (plantcell.org)
  • mature
  • A key question is how and why such intermediates are stabilized and how they can then be processed to the mature RNA. (asm.org)
  • whose
  • These so-called noncoding RNAs, whose existence was barely recognized a few years ago, are now considered as key players in a plethora of normal and pathological contexts. (fpwr.org)