• A primary transcript of the HIV provirus serves as the genomic RNA for future generations of HIV and is processed to ensure efficient translation of viral proteins. (jimmunol.org)
  • If the shRNA is expressed at levels that are too high the cell might not be able to correctly process the endogenous RNA which could cause significant problems. (wikipedia.org)
  • In vivo studies included serial MRI of NOD-SCID mice transplanted with MN-small interfering (si)Caspase-3-labeled human islets under the left kidney capsule and MN-treated islets under the right kidney capsule. (diabetesjournals.org)
  • Dalakouras A, Wassenegger M, McMillan JN, Cardoza V, Maegele I, Dadami E, Runne M, Krczal G, Wassenegger M (2016) Induction of silencing in plants by high-pressure spraying of in vitro-synthesized small RNAs. (springer.com)
  • During the viral life cycle, viral RNA is present in the cytoplasm of cells after fusion and before reverse transcription, which presents a target that when acted on can inhibit infection before proviral integration. (jimmunol.org)
  • The inhibition occurred at two points in the viral life cycle, after fusion and before reverse transcription and during transcription of viral RNA from integrated provirus. (jimmunol.org)
  • The external RNAs were capable of local and systemic movement inducing plant resistance against the pathogens. (springer.com)
  • Dubrovina AS, Kiselev KV (2019) Exogenous RNAs for gene regulation and plant resistance. (springer.com)