• Recent research has revealed the importance of DExD/H-box RHs in many aspects of plant RNA metabolism and physiological processes. (frontiersin.org)
  • The grasshopper Eyprepocnemis plorans harbors B chromosomes containing large amounts of ribosomal DNA (rDNA) units, some of which are eventually active, but the amount of rRNA transcripts contributed by B chromosomes, compared to those of the standard (A) chromosomes, is unknown. (springer.com)
  • Chromatin immunoprecipitation assays revealed that ErbB2 enhances binding of RNA Pol I to rDNA. (aacrjournals.org)
  • In addition, ErbB2 associated with rDNA, RNA Pol I, and β-actin, suggesting how it could stimulate rRNA production, protein synthesis, and increased cell size and cell growth. (aacrjournals.org)
  • Epigenetic changes accompanying plant cell dedifferentiation and differentiation are reported in 35S ribosomal DNA (rDNA) of tobacco ( Nicotiana tabacum ). (plantphysiol.org)
  • The data together indicate that the establishment of pluripotency and cell proliferation occurring with callus induction is associated with enhanced ribosomal RNA gene expression and overall rDNA hypomethylation, but is not associated with material-enhanced relaxation of chromatin structure (decondensation) at rDNA loci. (plantphysiol.org)
  • 18S-5.6S-25S and 5S ribosomal DNA (rDNA) sites were located by in situ hybridization to the three main species of the Saccharum genus. (ovid.com)
  • Here we describe the first direct method for the rapid coextraction of RNA and DNA from soil for the comparison of bacterial diversity by 16S rRNA reverse transcription-PCR (RT-PCR) and 16S ribosomal DNA (rDNA)-PCR. (asm.org)
  • Yet, epigenetic features of the ribosomal DNA (rDNA) operon and changes in the ribosome's molecular composition have been associated with disease phenotypes, suggesting that the ribosome itself may possess inherent regulatory capacity. (sciencemag.org)
  • Here, we show that Wnt5a rapidly represses rDNA gene transcription in breast cancer cells and generates a chromatin state with reduced transcription of rDNA by RNA polymerase I (Pol I). These effects were specifically dependent on Dishevelled1 (DVL1), which accumulates in nucleolar organizer regions (NORs) and binds to rDNA regions of the chromosome. (lu.se)
  • m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. (cusabio.com)
  • I was able to isolate the part of the 23S ribosomal RNA that constitutes the peptidyl transferase centre using site-directed RNaseH digestion followed by isolation with PAGE. (blogspot.com)
  • At the same time the first high resolution crystal structure of the ribosome was published, and I was able to use this data to visualize the spatial position of my modifications from five different bacteria and archaea, and showing that they were all positioned in the peptidyl transferase pocket facing outwards, away from the ribosomal RNA, and towards the amino-acetylated tRNAs. (blogspot.com)
  • Our understanding of transcriptome biology is undergoing a revolution that is revealing that the regulation of expression and the types and functions of RNA are far more complex than was previously thought. (thermofisher.com)
  • Regulation of Ribosomal RNA Production by RNA Polymerase I: Does Elongation Come First? (hindawi.com)
  • Although it has been known that nuclear RTKs associate with functions in RNA Pol II transcriptional regulation, DNA repair, and DNA replication ( 12-16 , 20 , 26-32 ), the biological significance and functions of the nuclear RTKs, including ErbB2, is still far from clear. (aacrjournals.org)
  • In fact, recent studies have shown that one mechanism of cell growth regulation is achieved through an insulin receptor signaling pathway, one of the most downstream targets of which is the ribosomal protein S6 ( Weinkove and Leevers, 2000 ). (biologists.org)
  • In the eukaryotic ribosomal RNA processing pathway, a complex of ten riboexo nucleases called the exosome that plays a central role in the precise formation of the 3' ends of several types of RNAs . (humpath.com)
  • The rapid divergence rates of variable regions in the ribosomal gene may permit answers to the question of time of separation of closely related species. (pnas.org)
  • Using outward-facing primers and PCR analysis of reverse-transcribed RNA, we observed several species of circANRIL isoforms. (nature.com)
  • 2. Physical mapping of 5S and 18S-26S ribosomal RNA gene families in diploid species. (springer.com)
  • Species-specific repeat units in the intergenic spacer of the ribosomal RNA cistron of Anopheles aquasalis Curry. (ajtmh.org)
  • One initial report [ 14 ] has suggested that nc-RNAs represent only a minor fraction of RNA in a mammalian cell and that most of these non-coding species consisted of intronic by-products generated from unspliced RNAs. (biomedcentral.com)
  • The remaining whole-transcriptome RiboMinus™ RNA is suitable for direct sequencing using any next-generation sequencing platforms or microarray analysis. (thermofisher.com)
  • Reversal of the group I intron self-splicing reaction, termed reverse splicing, coupled with reverse transcription and genomic integration potentially mediate an RNA-based intron mobility pathway. (biomedsearch.com)
  • However, the frequency and general role of an RNA-based mobility pathway in the spread of natural group I introns is still unclear. (biomedsearch.com)
  • In the nucleus, the complex appears to function in a regulated m RNA surveillance system that degrades transcripts in response to defects in the m RNA processing and export pathways. (humpath.com)
  • Here our analyses of RNA sequencing data identify the long noncoding RNA lncNB1 as one of the transcripts most over-expressed in MYCN-amplified, compared with MYCN-non-amplified, human neuroblastoma cells and also the most over-expressed in neuroblastoma compared with all other cancers. (garvan.org.au)
  • We show that the relative mass of RNA whose function and/or structure we do not understand (the so called 'dark matter' RNAs), as a proportion of all non-ribosomal, non-mitochondrial human RNA (mt-RNA), can be greater than that of protein-encoding transcripts. (biomedcentral.com)
  • RHs are enzymes that rearrange the secondary structure of RNA and RNP complexes in an energy-dependent manner ( Tanner and Linder, 2001 ). (frontiersin.org)