• binding The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. (wikipedia.org)
  • When the dsRNA is exogenous (coming from infection by a virus with an RNA genome or laboratory manipulations), the RNA is imported directly into the cytoplasm and cleaved to short fragments by Dicer. (wikipedia.org)
  • After comparing the RNA genome of this virus with that of other members of the Nodaviridae family, it was found to be different and therefore a new member of the Nodaviridae family. (wikipedia.org)
  • The processing of the polyprotein occurs in a highly regulated manner, with cleavage at the P2/3 junction influencing RNA template use during genome replication. (wikipedia.org)
  • In translation, messenger RNA (mRNA) is decoded in a ribosome, outside the nucleus, to produce a specific amino acid chain, or polypeptide. (wikipedia.org)
  • The Kozak sequence is not to be confused with the ribosomal binding site (RBS), that being either the 5' cap of a messenger RNA or an Internal ribosome entry site (IRES). (wikipedia.org)
  • The early-branching eukaryote Giardia lamblia is perhaps the only protozoan capable of colonizing the lumen of the upper small intestine of many vertebrates, including humans 6 . (nature.com)
  • In terms of crystal structure, the first Dicer to be explored was that from the protozoan Giardia intestinalis. (wikipedia.org)
  • This technique provides a method to harvest, normalize and quantify intracellular growth of bacterial pathogens that are pre-cultivated in natural protozoan host cells prior to infections of mammalian cells. (jove.com)
  • the presence of box C/D-like elements in two of the transcripts suggests that they are members of a class of small nucleolar RNAs (snoRNAs) that guide modification and cleavage of rRNAs. (asm.org)
  • Posttranscriptional modifications to the rRNAs, including endonucleolytic cleavage, 2′- O -ribose methylation and pseudouridinylation, are mediated by small, nucleolar RNAs (snoRNAs). (asm.org)
  • It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. (wikipedia.org)
  • Small nucleolar RNA TBR2 Galardi, S. (wikipedia.org)
  • A double-stranded length of RNA. (gettyimages.com)
  • Partitiviruses have double stranded RNA genomes divided into two genomic segments and there may be additional subgenomic segments. (wikipedia.org)
  • These short double-stranded fragments are called small interfering RNAs (siRNAs). (wikipedia.org)
  • R2D2 carries tandem double-stranded RNA-binding domains to recognize the thermodynamically stable terminus of siRNA duplexes, whereas Dicer-2 the other less stable extremity. (wikipedia.org)
  • In addition to these domains, hsDicer contains four other functional domains: two RNaseIII domains and two double stranded RNA binding domains (DUF283 and dsRBD). (wikipedia.org)
  • 1932. Experimental production of chains and its genetic consequences in the Ciliate Protozoan Colpidium campylum . (indiana.edu)
  • During the early 1960s, sophisticated genetic analysis of mutations in the lac operon of E. coli and in the rII locus of bacteriophage T4 were instrumental in defining the nature of both messenger RNA and the genetic code. (wikipedia.org)
  • The ciliates are a group of protozoans characterized by the presence of hair-like organelles called cilia, which are identical in structure to eukaryotic flagella, but are in general shorter and present in much larger numbers, with a different undulating pattern than flagella. (wikipedia.org)