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  • enzyme
  • Nucleoside modifications are interesting due to their already known roles in translation fidelity, enzyme recognition, disease progression, and RNA stability. (mdpi.com)
  • Plastid encoded RNA polymerase is a multimeric enzyme comparable to eubacterial RNA polymerases. (plantphysiol.org)
  • RSH is the major enzyme responsible for (p)ppGpp synthesis in response to amino acid deprivation (lack of Leu/Val) or mupirocin treatment. (asm.org)
  • Alarmone synthesis is linked to many physiological processes involving rRNA degradation, gene activation/repression, protein translation, enzyme activation, and replication. (asm.org)
  • Beadle and Tatum performed a series of complex experiments that led to the idea that one gene encodes one enzyme. (docplayer.net)
  • Transcription
  • These include the "Hairy Enhancer of Split" ( hes ) gene and HES-related transcription factors (Hrts) that are critically involved in mammalian cell differentiation. (ahajournals.org)
  • Sally's DNA sequence and m-RNA transcription are shown below. (studyres.com)
  • Using the transcription-regulatory network, sRNA targets tend to be under multiple regulation (higher indegree, p-val = 0.013) and the targets usually are important to the transfer of regulatory signals (higher betweenness, p-val = 0.012). (biomedcentral.com)
  • As was found for the protein-protein interaction network, the targets that are regulated by the same sRNA also tend to be closely knit within the transcription-regulatory network (larger density, p-val = 0.036), and inward interactions between them are greater than the outward interactions (higher in-degree ratio, p-val = 0.023). (biomedcentral.com)
  • In this article, we have made use of RPOTp and RPOTmp T-DNA insertion mutants to answer the question of whether both plastid-located phage-type RNA polymerases have overlapping or specific functions in plastid transcription. (plantphysiol.org)
  • HBV is unusual among DNA viruses because its replication involves reverse transcription of an RNA intermediate. (patentgenius.com)
  • enzymes
  • NEP enzymes represent a small family of monomeric phage-type RNA polymerases. (plantphysiol.org)
  • Transcriptional analysis showed that the RSH-dependent stringent control in S. aureus is characterized by repression of genes whose products are predicted to be involved in the translation machinery and by upregulation of genes coding for enzymes involved in amino acid metabolism and transport which are controlled by the repressor CodY. (asm.org)
  • rRNA gene
  • The genome contains no large inverted repeat and has one copy of rRNA gene cluster consisting of 16S, 23S, and 5S rRNA genes. (pnas.org)
  • Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain CMAA 1533(T) belongs to the family Nocardiaceae and forms a distinct phyletic line within the genus Rhodococcus. (readbyqxmd.com)
  • Analysis of the 16S rRNA gene sequences showed that strain CMAA 1215(T) forms a distinct phyletic line within the Pseudomonas putida subclade, being closely related to P. plecoglossicida ATCC 700383(T), P. monteilii NBRC 103158(T), and P. taiwanensis BCRC 17751(T) of sequence similarity of 98. (readbyqxmd.com)
  • The organism formed a distinct phyletic line in the Saccharopolyspora 16S rRNA gene tree and had chemotaxonomic and morphological properties consistent with its classification in this genus. (readbyqxmd.com)
  • It was found to be closely related to Saccharopolyspora dendranthemae KLBMP 1305T (99.5% 16S rRNA gene sequence similarity) and shared similarities of 99. (readbyqxmd.com)
  • polymerases
  • The plastid genome of higher plants is transcribed by two different types of RNA polymerases named nucleus encoded RNA polymerase (NEP) and plastid encoded RNA polymerase. (plantphysiol.org)
  • double-stranded
  • The endo-siRNA pathway, which produces small double-stranded RNAs in Drosophila, appears to be nonessential for robust development of the embryo under ambient uniform temperature and to be necessary only for viral defense. (jove.com)
  • E. DNA is always double-stranded and RNA is always single-stranded. (docplayer.net)
  • molecule
  • p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex). (uniprot.org)
  • bacterial
  • The most striking is the existence of two adjacent genes homologous to bacterial genes involved in cell division, minD and minE , which are arranged in the same order in Escherichia coli . (pnas.org)
  • The most notable feature of the genome is the existence of two genes homologous to bacterial genes ( minD and minE ) related to cell division. (pnas.org)
  • However, few sRNAs have been identified outside several well-studied species of gamma-proteobacteria and thus relatively little is known about the role of RNA-mediated regulation in most other bacterial genera. (biomedcentral.com)
  • stabilization
  • Amino acid starvation also provoked stabilization of the RNAs coding for major virulence regulators, such as SaeRS and SarA, independently of RSH. (asm.org)
  • species
  • In addition to these key players, many other RNA species have been identified such as long non-coding RNAs (lncRNAs), micro RNAs (miRNAs) or even enzymatic RNAs like RNase P [ 1 ]. (mdpi.com)
  • 1983). Subsequently, the NGF gene has been characterized in a number of other species including several mammals, birds, reptiles and fishes (Schwarz et al. (freepatentsonline.com)
  • The genome of H. duospinosa contains some unusual features including a Hox complex broken over two scaffolds, in a different manner to other arthropod species, a lack of odorant receptor genes and an apparent lack of environmentally responsive DNA methylation, unlike many other arthropods. (biomedcentral.com)
  • Such a revolutionary perspective has been accompanied and triggered by the development of powerful technologies for profiling short RNAs expression, both at the high-throughput level (genome-wide identification) or as single-candidate analysis (steady state accumulation of specific species). (jove.com)
  • Here we overview an efficient protocol (Enhanced Northern Blot) for detecting weakly expressed microRNAs (or other small regulatory RNA species) from Drosophila melanogaster whole embryos, manually dissected larval/adult tissues or in vitro cultured cells. (jove.com)
  • molecules
  • 2. The method of claim 1 wherein the fully processed RNAi trigger molecules are incorporated into a micro RNA (miRNA). (patentgenius.com)
  • Although several state-of-art strategies are currently available for dosing or visualizing such fleeing molecules, Northern Blot assay remains the eligible approach in molecular biology for immediate and accurate evaluation of RNA expression. (jove.com)
  • Two nectary types that evolved with Populus trichocarpa ( Ptr ) and Populus tremula × Populus tremuloides ( Ptt ) were studied from their ecology down to the genes and molecules. (plantphysiol.org)
  • genome
  • Genetics Lab Cystic Fibrosis Information source: http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/cftr.shtml Cystic fibrosis is a serious genetic disorder caused by a deletion mutation, ΔF508, of the CFTR (cystic fibrosis transmembrane conductance regulator) gene located on chromosome 7. (studyres.com)
  • For example, the chloroplast genome of the red alga Porphyra purpurea contains over 70 new genes not found in land plant and Euglena chloroplasts ( 4 , 7 ). (pnas.org)
  • organisms
  • Post-transcriptional RNA modifications have been found to be present in a wide variety of organisms and in different types of RNA. (mdpi.com)
  • Sequences
  • The monozoic caryophyllideans are considered the earliest diverging eucestodes based on partial mitochondrial genes and nuclear rDNA sequences, yet, there are currently no complete mitogenomes available. (biomedcentral.com)
  • The result produced by the comparison of two or more gene or protein sequences in order to determine their degree of base or amino acid similarity. (sdsc.edu)
  • Molecular
  • It is essential to stress that what has been discovered with yeast (molecular mechanisms underlying the diseases, nuclear correcting genes, import of tRNA into mitochondria or compounds from drug screening) has been successfully transferred to human patient lines, paving the way for future therapies. (mdpi.com)
  • This branch of molecular biology has been greatly fueled by the discovery of noncoding RNAs as major players in post-transcriptional regulation. (jove.com)
  • Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase. (semanticscholar.org)
  • regulate
  • However, we hypothesized that small RNAs may regulate the embryos response to temperature, as a ribonucleoprotein complex has been previously shown to mediate mammalian cell response to heat shock. (jove.com)
  • small
  • Recently, genes coding for additional small (p)ppGpp synthases were identified in most of the firmicutes ( 41 ). (asm.org)