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  • clinical
  • Reuters Health) - Scientists often fail to publicly register plans for clinical trials or to publish the results, and the outcomes they do share may mask instances when new treatments are unsafe or ineffective, a small study suggests. (reuters.com)
  • One goal of asking scientists to register clinical trial plans in public research databases is to highlight the main objective of experiments and make it easy to see whether a tested treatment achieved this goal when results are published, the study authors note in JAMA. (reuters.com)
  • For patients who want to do their own homework about their treatment options, systematic reviews that examine results from a variety of clinical trials are the best way to go, said Dr. Barbara Mintzes, a pharmacy researcher at the University of Sydney in Australia who wasn't involved in the study. (reuters.com)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • 20, Gleason score ≥ 8, OR clinical stage ≥ T3 Given the relative simplicity of the 1998 D'Amico criteria (above), other predictive models of risk stratification based on mathematical probability constructs exist or have been proposed to allow for better matching of treatment decisions with disease features. (wikipedia.org)
  • The rate of BPD varies among institutions, which may reflect neonatal risk factors, care practices (e.g., target levels for acceptable oxygen saturation), and differences in the clinical definitions of BPD. (wikipedia.org)
  • The CHADS2 score and its updated version, the CHA2DS2-VASc score, are clinical prediction rules for estimating the risk of stroke in patients with non-rheumatic atrial fibrillation (AF), a common and serious heart arrhythmia associated with thromboembolic stroke. (wikipedia.org)
  • In clinical use, the CHADS2 score (pronounced "chads two") has been superseded by the CHA2DS2-VASc score ("chads vasc" ), which gives a better stratification of low-risk patients. (wikipedia.org)
  • Even a single stroke risk factor confers excess risk of stroke and mortality, with a positive net clinical benefit for stroke prevention with oral anticoagulation, when compared to no treatment or aspirin. (wikipedia.org)
  • Health maintenance organizations (HMOs) that commonly cover the bulk of the population, restrict access to treatment via financial and clinical access limits. (wikipedia.org)
  • Some examples of improvements in process are: clinical practice guidelines, analysis of cost efficiency, and risk management, which consists of proactive steps to prevent medical errors. (wikipedia.org)
  • prevention
  • The objective of the collaboration is to find novel ways for clinicians to effectively present medical risk information to help cancer patients make their own informed decisions on the benefits of screening, prevention, or on their treatment management options. (prnewswire.com)
  • With the study results, researchers are hoping to develop useful tools that will support in the communication of cancer patients' risk profile, ultimately helping to foster compliance with cancer prevention and screening protocols. (prnewswire.com)
  • organization's
  • The criterion that is used in making the decision is simple: either the risk is within the organization's pre-determined, board-approved risk tolerance level, in which case it is accepted, or it is not, in which case it must be avoided, controlled or transferred. (oreilly.com)
  • anticoagulation therapy
  • Such a score is used to determine whether or not treatment is required with anticoagulation therapy or antiplatelet therapy, since AF can cause stasis of blood in the upper heart chambers, leading to the formation of a mural thrombus that can dislodge into the blood flow, reach the brain, cut off supply to the brain, and cause a stroke. (wikipedia.org)
  • Aspirin
  • The HAS-BLED score is recommended in guidelines, to identify the high risk patient for regular review and followup and to address the reversible risk factors for bleeding (e.g. uncontrolled hypertension, labile INRS, excess alcohol use or concomitant aspirin/NSAID use). (wikipedia.org)
  • objective
  • Among the unregistered trials, 55 percent of the results that were published had discrepancies, such as a primary outcome that changed after the trial started or a lowered bar for determining whether the treatment met its main objective in the experiment. (reuters.com)
  • 1. The primary objective is to determine the response rate (IWCLL/NCI-WG criteria) to treatment with single-agent ofatumumab in previously untreated, early stage, high-risk patients with CLL/SLL The secondary objectives are: 1. (mdanderson.org)
  • occur
  • Furthermore, seizures can occur with the use of Tramadol and risks may be higher in those who have had a seizure disorder, epilepsy, head injury or a metabolic disorder. (opiates.com)
  • patient
  • This treatment for DVT or pulmonary embolisms takes a condition that is life-threatening and makes it something the patient can control. (medicalxpress.com)
  • The Cochrane Collaboration, for example, publishes reviews of drug treatments with summaries of key findings, good and bad, that may help guide patient decisions, Mintzes said by email. (reuters.com)
  • The B-Cell Lymphoma Moon Shot is revolutionizing the conventional medical research approach to rapidly translate findings into patient treatment options and develop personalized therapeutic strategies. (mdanderson.org)
  • Scientists will review data from the patient-clinician interactions to extract insights into what visual communication features are most effective at accurately portraying the risks and the benefits to patients. (prnewswire.com)
  • The patient needs to be informed of the risks and benefits of PSA testing prior to performing the test (see below). (wikipedia.org)
  • Behavioral health outcome management (BHOM) involves the use of behavioral health outcome measurement data to help guide and inform the treatment of each individual patient. (wikipedia.org)
  • With formal assessments of patient needs, the clinician can devise an individualized treatment plan that incorporates these needs and evidence-based practices and principals. (wikipedia.org)
  • Obviously, the most fundamental use of BHOM is to use the data to track treatment progress on a patient-by-patient basis. (wikipedia.org)
  • diagnostic
  • IBM ) announced today they are collaborating on a study that will demonstrate the effects of how oncologists, integrating visual information into their consultations, assist in communicating the diagnostic and treatment risks to cancer patients. (prnewswire.com)
  • health
  • although in large dosages it can cause seizures or other health risks. (opiates.com)
  • Unpublished trials tend to be the ones that found treatments didn't work or weren't safe, said Roberta Scherer, a researcher at Johns Hopkins Bloomberg School of Public Health in Baltimore who wasn't involved in the study. (reuters.com)
  • Patients may not understand that publication doesn't guarantee they're getting complete information about a treatment, said Dr. Joseph Ross, a public health researcher at Yale School of Medicine in New Haven, Connecticut. (reuters.com)
  • For those 65 years old, Medicare pays for 50 percent of the costs of mental health treatment and will typically reimburse the remainder. (emaxhealth.com)
  • We provide integrated treatment for mental health disorders and addiction. (drugrehab.com)
  • Some health plans now require the integration of BHOM into routine care and treatment planning and a well designed BHOM system provides the clinician feedback and guidance to keep up with these evidence-based principals. (wikipedia.org)
  • patients
  • Researchers at the Indiana University School of Medicine treated 106 low-risk patients diagnosed with deep vein thrombosis or pulmonary embolism at two metropolitan emergency rooms. (medicalxpress.com)
  • Patients say treatment with no injections is a much better option. (medicalxpress.com)
  • This can put patients at risk, Scherer said by email. (reuters.com)
  • The worse-case scenario is that patients are receiving an ineffective treatment or possibly even a harmful treatment," Scherer added. (reuters.com)
  • Determine time-to-progression in high-risk patients treated with ofatumumab. (mdanderson.org)
  • 3. Evaluate the pharmacokinetics of single-agent ofatumumab in high-risk, previously treated patients with CLL.4. (mdanderson.org)
  • Evaluate for circulating CD20+ cells through treatment and in follow-up in high-risk patients treated with ofatumumab. (mdanderson.org)
  • 5. Evaluate safety and toxicities of ofatumumab in previously untreated high-risk patients with CLL/SLL. (mdanderson.org)
  • Communicating cancer risk information is a growing area of oncology and the process is a challenging one for both healthcare professionals and patients. (prnewswire.com)
  • Clinicians may find it difficult to translate risk statistics to individual patients and use only verbal communications to explain complex information. (prnewswire.com)
  • It requires specialist knowledge and understanding in order to inform patients about cancer risk, to change risk related behaviors, or to reassure people with excessive risk related anxieties,' says Professor Francois Eisinger , IPC. (prnewswire.com)
  • The design of the visual communication templates aims to deliver the information gathered from medical and statistical content such as inherited, biological and environmental risk factors and lifestyle habits that may influence the development of cancer in patients. (prnewswire.com)
  • Treatment recommendations based on the CHA2DS2-VASc score are shown in the following table: Based on the ESC guidelines on Atrial Fibrillation, oral anticoagulation is recommended or preferred for patients with one or more stroke risk factors (i.e. a CHA2DS2-VASc score of ≥1 in males, or ≥2 in females). (wikipedia.org)
  • The most significant disease affecting risk however is not genetically linked - patients with acquired cystic disease of the kidney requiring dialysis are 30 times more likely than the general population to develop RCC. (wikipedia.org)
  • Especially with session-by-session assessments, real-time scoring and report generation the data provides clinicians and patients with excellent feedback about the course of treatment and whether adjustments need to be made to the treatment plan. (wikipedia.org)
  • subsequent
  • These changes can result in the thickening of the uterine lining and a subsequent increased risk for cell abnormality and cancer. (healthline.com)
  • medical
  • Risk through medical procedures is very low as all donated blood is checked for West Nile virus before being used and the risk of getting West Nile virus through blood transfusions and organ transplants is very small, and should not prevent people who need surgery from having it. (news-medical.net)
  • Therefore, it is best to seek medical guidance or an inpatient medical facility to minimize suffering and risks. (opiates.com)
  • There are many challenges to communicating medical risks for individualized cancer treatments. (prnewswire.com)
  • disease
  • Who is at risk for hand, foot, and mouth disease? (healthline.com)
  • Young children have the highest risk of getting hand, foot, and mouth disease. (healthline.com)
  • So far, no treatment has been shown to prevent or delay the progression of the disease. (empowher.com)
  • DrugRehab.com provides information regarding illicit and prescription drug addiction, the various populations at risk for the disease, current statistics and trends, and psychological disorders that often accompany addiction. (drugrehab.com)
  • Thus, the CHA2DS2-VASc score is a refinement of CHADS2 score and extends the latter by including additional common stroke risk factors, that is, age 65-74, female gender and vascular disease. (wikipedia.org)
  • It is used in the treatment of autoimmune diseases (for example rheumatoid arthritis or Behcet's Disease) and in transplantations. (wikipedia.org)
  • Treatment of secondary membranous nephropathy is guided by the treatment of the original disease. (wikipedia.org)
  • nursing care
  • In more severe cases, people are often hospitalized where they can receive supportive treatment including intravenous fluids, help with breathing and nursing care. (news-medical.net)
  • options
  • In this section, you will find information and resources related to evidence-based treatment models, counseling and therapy and payment and insurance options. (drugrehab.com)
  • cases
  • Researchers at Brigham Young and other universities have clinically proven that BHOM helps therapists to deliver better care by identifying cases that are not likely to improve with the current treatment plan. (wikipedia.org)
  • provide
  • Other standards in the ISO/IEC 27000 family of standards provide additional guidance on certain aspects of designing, implementing and operating an ISMS, for example on information security risk management (ISO/IEC 27005). (wikipedia.org)
  • Plan (establishing the ISMS) Establish the policy, the ISMS objectives, processes and procedures related to risk management and the improvement of information security to provide results in line with the global policies and objectives of the organization. (wikipedia.org)
  • exposure
  • If you got your first menstrual period before you were age 12, you have an increased risk of endometrial cancer because of your body's increased exposure to estrogen over your lifetime. (healthline.com)
  • Exposure to Agent Orange and certain insecticides might also be a risk. (wikipedia.org)
  • protocols
  • One in five trials didn't define a primary outcome, or clear protocols for determining if the tested treatment had achieved its main goal. (reuters.com)
  • side effects
  • Therefore, many will experience the side effects of treatment, such as for every 1000 men screened, 29 will experience erectile dysfunction, 18 will suffer urinary incontinence, 2 will have serious cardiovascular events, 1 will suffer pulmonary embolus or deep venous thrombosis, and 1 perioperative death. (wikipedia.org)
  • found
  • Finally, studies have found that women who have had a hysterectomy are at more than double the risk of developing RCC than those who have not. (wikipedia.org)
  • severe
  • A severe hypoglycemic attack is when blood sugar dips so dangerously low that you risk losing consciousness. (healthline.com)
  • results
  • Adding together the points that correspond to the conditions that are present results in the CHADS2 score, that is used to estimate stroke risk. (wikipedia.org)
  • addiction
  • Treatment for addiction takes many forms and depends on the needs of the individual. (drugrehab.com)
  • In accordance with the American Society of Addiction Medicine, we offer information on outcome-oriented treatment that adheres to an established continuum of care. (drugrehab.com)
  • With the right balance of treatment, support and effort, recovery from benzodiazepine addiction is possible. (drugrehab.com)
  • higher
  • People who have hereditary nonpolyposis colorectal cancer (HNPCC) have a higher-than-normal risk of developing endometrial cancer. (healthline.com)
  • The risk for men that have sex with men (MSM) is higher. (wikipedia.org)