Risk of tendon fluoroquinolone use outweighs the risk fluoroquinolones. Medical search. Frequent questions

The U.S. Food and Drug Administration (FDA) recently released new warnings on the "disabling" side effects from the commonly used class of antibiotics called fluoroquinolones. (thelyonfirm.com)
Levaquin, Avelox and Cipro all belong to a class of antibiotics called fluoroquinolones. (rxinjuryhelp.com)
Due to side effects, the medication was quickly stopped, and in total, he took just seven pills of ciprofloxacin (Cipro) - one of a class of powerful, widely prescribed antibiotics called fluoroquinolones - according to records Oliver and his siblings kept. (wtop.com)
Noroxin belongs to a group of antibiotics called fluoroquinolones, which work by killing the bacteria that cause the infections. (rxwiki.com)

Spontaneous reports to the U.S. FDA Adverse Effects Reporting System at the time of the 20 September 2011 U.S. FDA Pediatric Drugs Advisory Committee included musculoskeletal events (39, including five cases of tendon rupture) and central nervous system events (19, including five cases of seizures) as the most common spontaneous reports between April 2005 and March 2008. (wikipedia.org)
Another study published in BMJ Open in November 2015 looked at data on over 1.7 million older adults and found a roughly 3-fold increased risk of tendon rupture and aortic aneurysm among patients who took fluoroquinolone antibiotics. (prescriptiondrugjournal.com)
These individuals were 3.13 times more likely to suffer a tendon rupture and 2.72 times more likely to suffer an aortic aneurysm compared to patients who did not take fluoroquinolones. (prescriptiondrugjournal.com)
That year they added the "black box" warning to seven fluoroquinolone drug labels and prescribing information, primarily because of the added risk of tendon rupture. (thelyonfirm.com)
The labels of fluoroquinolone medicines already have a Boxed Warning for tendinitis, tendon rupture, and worsening of myasthenia gravis. (fluoridationaustralia.com)
It is already known that these drugs can severely exacerbate the risk of tendinitis, tendon rupture, prolongation of the QT interval, and peripheral neuropathy. (rheingoldlaw.com)
Most published comparative trials describe these risks among the drug class, but do not focus on the incidence of serious arrhythmias, seizures, hallucinations tendon rupture, or photosensitivity. (rheingoldlaw.com)
Additionally, Ciprofloxacino can increase the risk of tendonitis and tendon rupture, especially in older adults or individuals who participate in physical activities or have a history of tendon problems. (babieblue.com)
Another important precaution to bear in mind is that Ciprofloxacino may increase the risk of tendinitis and tendon rupture, particularly in individuals over the age of 60, those on corticosteroid therapy, and those with a history of tendon disorders. (babieblue.com)
May have increased risk of tendinopathy (including rupture), especially with concomitant corticosteroid use (5.2, 8.5, 17). (drugcentral.org)

In community-acquired infections, they are recommended only when risk factors for multidrug resistance are present or after other antibiotic regimens have failed. (wikipedia.org)
Meta-analyses conclude that fluoroquinolones pose little or no additional risk to children compared to other antibiotic classes. (wikipedia.org)
The antibiotic medication Factive has been linked to serious side effects including nerve damage (peripheral neuropathy), tendon damage, aortic aneurysm and aortic dissection. (prescriptiondrugjournal.com)
Factive (gemifloxacin) is a fluoroquinolone antibiotic that fights bacteria in the body. (prescriptiondrugjournal.com)
In 2006, my doctor prescribed me Levaquin-a fluoroquinolone antibiotic-for a suspected sinus infection. (cdc.gov)
Many victims have suffered adverse events after being unnecessarily prescribed a fluoroquinolone antibiotic. (cdc.gov)
Educating healthcare providers and patients about improving antibiotic prescribing and use and raising awareness about the risks of fluoroquinolones will help reduce the likelihood that others suffer the same fate. (cdc.gov)
The FDA's recent action follows a study by its Office of Surveillance and Epidemiology, which found "an association between fluoroquinolone antibiotic use and disabling peripheral neuropathy. (thelyonfirm.com)
Fluoroquinolones are antibiotic medicines that work by killing or stopping the growth of bacteria that can cause illness. (fluoridationaustralia.com)
More than 25 million fluoroquinolone antibiotic prescriptions are filled every year in the U.S. alone by people who are suffering common illnesses like urinary tract infections, bronchitis, and sinus infections. (ifspb.com)
Ciprofloxacino, commonly known as Cipro, is a medication classified as a fluoroquinolone antibiotic. (babieblue.com)
This antibiotic should not be used if you have a known hypersensitivity to fluoroquinolones or any of the ingredients present in Ciprofloxacino. (babieblue.com)
Levofla belongs to the fluoroquinolone antibiotic class. (healthsoothe.com)

The most commonly prescribed fluoroquinolones are Levaquin (levofloxacin), Cipro (ciprofloxacin), and Avelox (moxifloxacin). (cdc.gov)
LEFLOX 500MG (LEVOFLOXACIN 500MG) - 5 TABLETS is available in Kenyan Pharmacies and contains Levofloxacin, the S-(-)-isomer of the fluoroquinolone antibacterial ofloxacin. (epharmacyke.com)
Levofloxacin is the S-(-)-isomer of the fluoroquinolone antibacterial ofloxacin. (epharmacyke.com)
The range of adverse effects associated with Levofloxacin and the other fluoroquinolone antibacterials is broadly similar to that with earlier quinolones such as nalidixic acid. (epharmacyke.com)
There is some evidence that Levofloxacin use may be associated with an increased risk of colonisation by meticillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. (epharmacyke.com)
Since Levofloxacin and related fluoroquinolones have, like nalidixic acid, been shown to cause degenerative changes in weight-bearing joints of young animals , licensing information in the Kenya by The Pharmacy and Poisons Board that these drugs should not be used in children, adolescents, pregnant women, or breast-feeding mothers. (epharmacyke.com)
An adequate fluid intake should be maintained during treatment with Levofloxacin and excessive alkalinity of the urine avoided because of the risk of crystalluria. (epharmacyke.com)
Since Levofloxacin and other fluoroquinolones can cause degenerative changes in weight-bearing joints of young animals they should only be used in children and adolescents in Kenya where their use is deemed to outweigh the risks. (epharmacyke.com)
Fluoroquinolones, including levofloxacin, may exacerbate muscle weakness in patients with myasthenia gravis. (nih.gov)
Levofloxacin is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with infections caused by designated, susceptible bacteria and in pediatric patients where indicated (1, 12.4). (nih.gov)
Levofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. (drugcentral.org)
Based on data on other fluoroquinolones and very limited data on levofloxacin, it can be presumed that levofloxacin will be excreted in human milk. (drugcentral.org)
The risk-benefit assessment indicates that administration of levofloxacin to pediatric patients is appropriate. (drugcentral.org)
Although doxycycline alone usually is the drug of choice for the treatment of acute Q fever caused by Coxiella burnetii, doxycycline has been used in conjunction with hydroxychloroquine or a fluoroquinolone (e.g., levofloxacin, ofloxacin) for the treatment of Q fever endocarditis. (antiinfectivemeds.com)

In 2013, the FDA issued a warning about permanent nerve damage as a possible fluoroquinolones injury, such as Cipro and others. (thelyonfirm.com)
There she found many warnings about the potential risks of fluoroquinolones, including cipro. (theheartysoul.com)
Plaintiffs pursuing lawsuits against the manufacturers of Levaquin, Cipro and Avelox claim that the association between fluoroquinolones and peripheral neuropathy was recognized as early as the 1990s. (rxinjuryhelp.com)
In fact, fluoroquinolone antibiotics like Levaquin, Cipro, and Avelox are just a few of the most commonly prescribed medications for those types of illnesses. (ifspb.com)
Always consult with your healthcare provider to ensure that the benefits of using Cipro outweigh the potential risks for your specific situation. (mypucc.com)

A study published in the Annals of Pharmacotherapy in December 2001 found that fluoroquinolone antibiotics like Factive can cause severe, long-term nerve damage involving multiple organ systems. (prescriptiondrugjournal.com)
A study published in JAMA Internal Medicine in November 2015 found that fluoroquinolone antibiotics may cause the aorta - the largest artery in the human body - to become abnormally enlarged. (prescriptiondrugjournal.com)
Safety Announcement [12-20-2018] A U.S. Food and Drug Administration (FDA) review found that fluoroquinolone antibiotics can increase the occurrence of rare but serious events of ruptures or tears in the main artery of the body, called the aorta. (kpaddock.com)

FDA has issued at least two warnings about the rapid onset of peripheral neuropathy and the risk of permanent nerve damage associated with fluoroquinolone antibiotics like Factive. (prescriptiondrugjournal.com)
"The onset of peripheral neuropathy after starting fluoroquinolone therapy was rapid, often within a few days," FDA said. (prescriptiondrugjournal.com)
December 2001 - Study published in the Annals of Pharmacotherapy finds an increased risk of severe, long-term peripheral neuropathy with fluoroquinolone antibiotics. (prescriptiondrugjournal.com)
Health care professionals should avoid prescribing fluoroquinolone antibiotics to patients who have an aortic aneurysm or are at risk for an aortic aneurysm, such as patients with peripheral atherosclerotic vascular diseases, hypertension, certain genetic conditions such as Marfan syndrome and Ehlers-Danlos syndrome, and elderly patients. (kpaddock.com)
The labels also include warnings about the risks of peripheral neuropathy and central nervous system effects. (fluoridationaustralia.com)
After FDA's 2013 review that led to the additional warning that peripheral neuropathy may be irreversible, FDA evaluated post-marketing reports* of apparently healthy patients who experienced disabling and potentially permanent side effects involving two or more body systems after being treated with a systemic fluoroquinolone (see Data Summary ). (fluoridationaustralia.com)

The FDA's warnings, placed on the drugs' labels and warning inserts, aim to inform patients that the serious side effects of these medications generally outweigh the benefits, particularly if patients have other treatment options. (thelyonfirm.com)

In 2016, the FDA found that systemic use (by mouth or injection) of fluoroquinolones was associated with "disabling and potentially permanent serious side effects" involving the tendons, muscles, joints, nerves, and central nervous system, concluding that these side effects generally outweigh the benefits for people with acute sinusitis, acute bronchitis, and uncomplicated urinary tract infections when other treatment options are available. (wikipedia.org)
They can occur with fluoroquinolones for systemic use given by mouth or through an injection. (kpaddock.com)
Without treatment, some infections can spread and lead to serious health problems (see List of Currently Available FDA-Approved Systemic Fluoroquinolones). (kpaddock.com)
7-26-2016 ] The U.S. Food and Drug Administration (FDA) approved changes to the labels of fluoroquinolone antibacterial drugs for systemic use (i.e., taken by mouth or by injection). (fluoridationaustralia.com)
Health care professionals should not prescribe systemic fluoroquinolones to patients who have other treatment options for acute bacterial sinusitis (ABS), acute bacterial exacerbation of chronic bronchitis (ABECB), and uncomplicated urinary tract infections (UTI) because the risks outweigh the benefits in these patients. (fluoridationaustralia.com)
Stop fluoroquinolone treatment immediately if a patient reports serious side effects, and switch to a non-fluoroquinolone antibacterial drug to complete the patient's treatment course (see List of Currently Available FDA-approved Fluoroquinolones for Systemic Use ). (fluoridationaustralia.com)
According to the agency, fluoroquinolones intended for systemic use are associated with disabling complications affecting the tendons, muscles, joints, nerves, and central nervous system. (rxinjuryhelp.com)
The black box warning included on the labeling for all systemic fluoroquinolones (those administered orally or via injection) has since been updated to reflect this information. (rxinjuryhelp.com)

In May 2016, the FDA required fluoroquinolone labels to be updated with a warning about an increased risk for damage to muscles, nerves and more. (prescriptiondrugjournal.com)
We previously communicated about these safety issues associated with fluoroquinolones in May 2016 . (fluoridationaustralia.com)

the risk also may be higher among people who are male, have a pre-existing joint or tendon issue, have kidney disease, or are highly active. (wikipedia.org)
Some signs and symptoms of serious side effects include unusual joint or tendon pain, muscle weakness, a "pins and needles" tingling or pricking sensation, numbness in the arms or legs, confusion, and hallucinations. (fluoridationaustralia.com)

If tendonitis occurs, it generally appears within one month, and the most common tendon injured appears to be the Achilles tendon. (wikipedia.org)
A few weeks later, I ruptured my Achilles tendon while walking across a parking lot to my car. (cdc.gov)
Soon afterward she began experiencing more problems like this: A dislocated shoulder, three tears to her achilles tendon, and painful ruptures to the ligaments in her wrists. (theheartysoul.com)

Fluoroquinolones are often used for genitourinary infections and are widely used in the treatment of hospital-acquired infections associated with urinary catheters. (wikipedia.org)
The agency said risks of the drugs may outweigh the benefits in patients with sinusitis, bronchitis and uncomplicated urinary tract infections. (prescriptiondrugjournal.com)
Per the Food and Drug Administration (FDA), prescribing fluoroquinolones for acute bacterial sinus infections, acute bacterial exacerbation of chronic bronchitis, or uncomplicated urinary tract infections can put a patient at risk for severe, disabling, and often permanent adverse reactions. (cdc.gov)
For those infections, the risks outweigh the benefits. (cdc.gov)
In November 2015, the FDA held an Advisory Committee Hearing about the risks versus benefits of fluoroquinolones, at which I testified, and the panel concluded that the serious risks associated with the use of fluoroquinolones for these types of uncomplicated infections generally outweighed the benefits for patients with other treatment options. (cdc.gov)
Guidelines recommend alternatives to fluoroquinolone antibiotics to treat minor, uncomplicated infections. (cdc.gov)
Had we known that the risks of fluoroquinolones outweigh the benefits for some infections, we would have discussed alternative treatment recommendations with our doctors. (cdc.gov)
Fluoroquinolone antibiotics are approved to treat certain bacterial infections and have been used for more than 30 years. (kpaddock.com)
Despite the warnings and the potential hundreds of thousands of lives that fluoroquinolones have affected, doctors continue to prescribe them for simple infections like those of the sinuses and the urinary tract. (theheartysoul.com)
We have determined that fluoroquinolones should be reserved for use in patients who have no other treatment options for acute bacterial sinusitis, (ABS), acute bacterial exacerbation of chronic bronchitis (ABECB), and uncomplicated urinary tract infections (UTI) because the risk of these serious side effects generally outweighs the benefits in these patients. (fluoridationaustralia.com)
For some serious bacterial infections the benefits of fluoroquinolones outweigh the risks, and it is appropriate for them to remain available as a therapeutic option. (fluoridationaustralia.com)
Last May, the U.S. Food & Drug Administration (FDA) warned that fluoroquinolone antibiotics shouldn't be prescribed for patients with acute sinusitis, acute bronchitis, and uncomplicated urinary tract infections when other treatment options are available. (rxinjuryhelp.com)
Recent data suggests that the benefits of fluoroquinolones do not outweigh the adverse effects of the drugs for patients with sinusitis, bronchitis, and uncomplicated urinary tract infections (UTIs) who have other treatment options - prompting the U.S. Food and Drug Administration to issue a safety alert as well as updated drug label. (rheingoldlaw.com)
As members of the fluoroquinolone class of antibiotics, Ciprofloxacin , in particular, has established itself as a cornerstone in combating a wide range of bacterial infections. (mypucc.com)
However, long-term usage might amplify the risk of severe side effects like tendon damage, liver problems, intestinal infections, or nerve issues. (mypucc.com)

This is a part of a group of antibiotics known as fluoroquinolones. (theheartysoul.com)

The update indicates that there were 738 fluoroquinolone lawsuits pending in the litigation as of the date of the conference, the majority of which focus on Janssen Pharmaceutical's Levaquin. (rxinjuryhelp.com)
The goal of this report is to help you understand the serious side effects that have been associated with fluoroquinolones like Levaquin and explore the options that may be available to you or your loved ones who have been injured by these drugs. (ifspb.com)
Levaquin and other fluoroquinolones have also been associated with retinal detachment and permanent vision loss. (ifspb.com)

Prescribe fluoroquinolones to these patients only when no other treatment options are available. (kpaddock.com)

Her doctors prescribed her powerful fluoroquinolones for a simple urinary tract infection, and her life has never been the same since. (theheartysoul.com)
The news is especially troubling, as fluoroquinolones are a class of antibacterial drugs that had been used precisely for the treatment of its contraindications: acute bacterial sinusitis (ABS), acute bacterial exacerbation of chronic bronchitis in those with chronic obstructive pulmonary disease (ABECB-COPD), and uncomplicated urinary tract infection. (rheingoldlaw.com)

Recent studies, published by the American Medical Association and numerous medical journals, show a link between the use of fluoroquinolone antibiotics and a substantial risk for aortic aneurysms and aortic dissections. (thelyonfirm.com)

However, for serious acute cases of pyelonephritis or bacterial prostatitis where the person may need to be hospitalised, fluoroquinolones are recommended as first-line therapy. (wikipedia.org)

Since that time, I have suffered 24 tendon ruptures, each of which required extensive reconstructive surgeries. (cdc.gov)
The 2015 studies identify a logical "association" between fluoroquinolone use and the development of severe aortic disorders, including fatal aortic ruptures. (thelyonfirm.com)

People at increased risk include those with a history of blockages or aneurysms (abnormal bulges) of the aorta or other blood vessels, high blood pressure, certain genetic disorders that involve blood vessel changes, and the elderly. (kpaddock.com)

Taking an NSAID while you take Noroxin or other fluoroquinolones may increase your risk of central nervous system effects and seizures. (rxwiki.com)

These medicines are associated with disabling and potentially permanent side effects of the tendons, muscles, joints, nerves, and central nervous system that can occur together in the same patient. (fluoridationaustralia.com)
But that was enough to begin a broad spectrum of rare but serious side effects that can occur with fluoroquinolones, which are now recognized by the Food and Drug Administration after years of patient advocacy, called fluoroquinolone-associated disability, or FQAD. (wtop.com)
In more temperate regions, seasonal variations in diarrhea risk can occur. (cdc.gov)

Researchers studied the risk of aortic dissection and aortic aneurysm in patients taking oral fluoroquinolone medications. (ifspb.com)

Fluoroquinolones can increase the rate of rare but serious tears in the aorta by 31% compared to other antibiotics. (wikipedia.org)
05-10-2017] As part of our ongoing review of fluoroquinolone antibiotics, FDA is informing the public that patient cases identified by the FDA and findings from published studies currently do not support reports that these medicines may result in detachment of the retina in the eyes, or bulges or tears in the aorta blood vessel called aortic aneurysm and aortic dissection. (fluoridationaustralia.com)

and inflammation of the colon (colitis), but clindamycin , penicillins, cephalosporins, and fluoroquinolones are the most common causes. (msdmanuals.com)

Attorneys for the plaintiffs are meeting and conferring with defense counsel regarding a bellwether trial proposal for 14 fluoroquinolone lawsuits currently pending in Pennsylvania's Court of Common Pleas. (rxinjuryhelp.com)

Fluoroquinolone side effects may include damage to tendons, muscles, joints, nerves and the central nervous system. (prescriptiondrugjournal.com)
The most severe side effects can involve damage to tendons, muscles, joints, nerves and the central nervous system. (thelyonfirm.com)
i] Collagen is found in connective tissue, skin and tendons, muscles, and even bones. (ifspb.com)

"Use of fluoroquinolones was associated with an increased risk of aortic aneurysm and dissection," the researchers concluded. (prescriptiondrugjournal.com)
Stop fluoroquinolone treatment immediately if a patient reports side effects suggestive of aortic aneurysm or dissection. (kpaddock.com)
They published the findings of their original investigation in JAMA Internal Medicine, after determining that these drugs were associated with an increased risk of an aortic aneurysm and dissection. (ifspb.com)

In 2008, the U.S. FDA added black box warnings on all fluoroquinolones, advising of the increased risk of tendon damage. (wikipedia.org)
In the FDA Adverse Event Reporting database, there are over 1,000 reports of nerve damage after fluoroquinolone use, and only 10 percent reported improvement or recovery. (thelyonfirm.com)
One of the biggest concerns with the use of these drugs is the host of serious side effects that they are associated with including vision problems, tendon injuries, nerve damage, and potentially fatal internal complications. (ifspb.com)
Researchers have shown that fluoroquinolone antibiotics like these can damage collagen proteins. (ifspb.com)
Tendon damage has been reported. (epharmacyke.com)

Corticosteroids taken by mouth or by injection may increase the chance of tendon injury. (rxwiki.com)

In some patients the symptoms had been ongoing for more than a year despite discontinuation of the fluoroquinolone. (prescriptiondrugjournal.com)
Several patients were continued on the fluoroquinolone drug despite the occurrence of neuropathic symptoms. (prescriptiondrugjournal.com)
Approximately 30% of patients in the study had filled at least one fluoroquinolone prescription in the last 30 days. (prescriptiondrugjournal.com)
For patients with these conditions, fluoroquinolones should only be prescribed when there are no other treatment options, according to the FDA. (prescriptiondrugjournal.com)
It is important that both patients and healthcare providers are aware of both the risks and benefits of fluoroquinolones and make an informed decision about their use. (cdc.gov)
Despite several FDA Black Box warnings on fluoroquinolones, they are still commonly prescribed because these warnings are not reaching their intended audiences-healthcare providers and patients. (cdc.gov)
Fluoroquinolones should not be used in patients at increased risk unless there are no other treatment options available. (kpaddock.com)
The FDA says that for some patients in specific circumstances, the benefits might outweigh the risks. (theheartysoul.com)
Patients must contact your health care professional immediately if you experience any serious side effects while taking your fluoroquinolone medicine. (fluoridationaustralia.com)
subsequent use of fluoroquinolones is contra-indicated in these patients. (epharmacyke.com)

However, the drugs have faced scrutiny in recent years amid concerns that their risks may outweigh their benefits. (rxinjuryhelp.com)

Be aware that symptoms of an aortic aneurysm often do not show up until the aneurysm becomes large or bursts, so report any unusual side effects from taking fluoroquinolones to your health care professional immediately. (kpaddock.com)

We are requiring that a new warning about this risk be added to the prescribing information and patient Medication Guide for all fluoroquinolones. (kpaddock.com)
In July of this year, adding to other black box warnings - the strongest warning that can be put on medication - the FDA announced that it was again requiring labeling information to be updated for fluoroquinolones. (wtop.com)
Pharmacist Jobby John, PharmD summarizes the uses, common side effects, and warnings for the fluoroquinolone antibiotics class of medication. (rxwiki.com)

It belongs to the fluoroquinolones class of antibiotics. (mypucc.com)
Levofla belongs to a class of drugs known as fluoroquinolone antibiotics. (healthsoothe.com)

As far back as 2008 the FDA knew about major concerns and risks for this class of antibiotics. (thelyonfirm.com)
Fluoroquinolones are a class of antibiotics that have been on the market since the 1980s. (theheartysoul.com)

In most countries, fluoroquinolones are approved for use in children only under narrowly defined circumstances, owing in part to the observation of high rates of musculoskeletal adverse events in fluoroquinolone-treated juvenile animals. (wikipedia.org)

The side effects occurred within hours to weeks after starting the fluoroquinolone, and at the time we received the reports, the side effects had continued for an average of 14 months to as long as 9 years after stopping the medicines. (fluoridationaustralia.com)

The current labelling already includes warnings about the risks for each of these adverse effects, as well as other central nervous system effects, Torsades de Pointes, phototoxicity, hypersensitivity, and myasthenia gravis exacerbation. (rheingoldlaw.com)

Due to people with sickle-cell disease being at increased risk for developing osteomyelitis from the Salmonella, fluoroquinolones are the "drugs of choice" due to their ability to enter bone tissue without chelating it, as tetracyclines are known to do. (wikipedia.org)

citation needed] Fluoroquinolones are featured prominently in guidelines for the treatment of hospital-acquired pneumonia. (wikipedia.org)
Fluoroquinolone use in children may be appropriate when the infection is caused by multidrug-resistant bacteria, or when alternative treatment options require parenteral administration and oral therapy is preferred. (wikipedia.org)

Anatomy5

Organisms26

Diseases31

Chemicals and Drugs45

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Phenomena and Processes14

Information Science1

Health Care3

Geographicals1

Antibiotics called fluoroquinolones4

Rupture10

Antibiotic13

Levofloxacin14

Cipro5

Found that fluoroquinolone antibiotics3

Peripheral6

Generally outweigh the benefits1

Systemic8

20162

Joint or tendon2

Achilles3

Infections15

Group of antibiotics1

Levaquin3

Prescribe1

Urinary tract inf2

Aortic aneurysms1

Bacterial1

Ruptures2

Aneurysms1

Seizures1

Occur3

Medications1

Aorta2

Inflammation1

Lawsuits1

Muscles3

Dissection3

Damage5

Injection1

Patients10

Benefits1

Symptoms1

Medication3

Belongs2

Class2

Adverse events1

Side1

Warnings about the risks1

Drugs1

Treatment2