• Using federated learning, we aimed to develop a tool to identify a group of women at low risk of pN+, to guide the shared decision-making process concerning the extent of lymph node dissection. (lu.se)
  • Based on an international privacy-preserving analysis, we developed a useful tool to guide the shared decision-making process regarding lymph node dissection. (lu.se)
  • Goal: To explore risk factors for lymph node metastases in early gastric malignancy (EGC) and to confirm the appropriate range of lymph node dissection. (bioskinrevive.com)
  • To investigate the potential risk factors for occult lateral cervical lymph node metastasis (LNM) to levels â ¢ and â £ in patients with papillary thyroid carcinoma (PTC) and the necessity of super-selective lateral lymph node dissection for patients harboring these metastases . (bvsalud.org)
  • All patients underwent lymph node dissection in levels â ¢ and â £ on the basis of original thyroid collar incision after LNM to level â ¥ was confirmed by preoperative fine needlebiopsy or intraoperative frozen pathology . (bvsalud.org)
  • Lymph node dissection in levels â ¢ and â £ could be considered for selective patients , since it will help to avoid secondary operation for residual tumor or recurrence resulted from insufficient treatment without increasing the incidence of complications or affecting patients ' appearances. (bvsalud.org)
  • The purpose of this study is to investigate risk factors of lymph node metastasis in cN0 NSCLC, thereby to identify the surgical indications for lymph node dissection in cN0 NSCLC. (biomedcentral.com)
  • 16.5 mm, the probability of lymph node metastasis is higher and lymph node dissection is recommended. (biomedcentral.com)
  • The current standard method for early NSCLC surgery is lobectomy combined with complete lymph node dissection or sampling [ 6 ]. (biomedcentral.com)
  • Therefore, whether patients with cN0 NSCLC need lymph node dissection or sampling has become a focus of attention. (biomedcentral.com)
  • We selected cN0 NSCLC patients with tumor diameter ≤ 30 mm and without imaging metastatic lymph nodes before surgery to study the incidence and risk factors for lymph node metastasis, thereby to provide the surgical indications for lymph node dissection in cN0 NSCLC. (biomedcentral.com)
  • Even with poor differentiation and SM2 invasion, EBV-GCLS showed very low risk of LNM and may be a candidate for endoscopic therapy such as endoscopic submucosal dissection. (biomedcentral.com)
  • Objective: To assess whether the risk for nonsentinel node metastases may be predicted, thus sparing a subgroup of patients with breast carcinoma and a positive sentinel lymph node (SLN) biopsy completion axillary lymph node dissection (ALND). (uniba.it)
  • Retrospective study of 57 consecutive patients treated by ILP for limb STS with simultaneous radical lymph node dissection in our tertiary referral center between 1992 and 2015. (jcancer.org)
  • Radical lymph node dissection should be included in ILP procedure. (jcancer.org)
  • Three decades ago, former studies have retained that there was no indication for systematic radical lymph node dissection even in case of locally advanced disease [ 8 - 10 ]. (jcancer.org)
  • Despite an increasing interest for radical lymph node dissection as part of treatment for sarcomas, there is currently no study on a standardized population in which radical lymph node dissection was performed systematically. (jcancer.org)
  • Background: Long-term outcomes of patients treated with salvage lymph node dissection (sLND) for nodal recurrence of prostate cancer (PCa) remain unknown. (uni-koeln.de)
  • Patient summary: We assessed long-term outcomes of patients treated with salvage lymph node dissection (sLND) for node-recurrent prostate cancer (PCa). (uni-koeln.de)
  • Select patients with papillary thyroid carcinoma with clinically involved lateral neck nodes (cN1b disease) may not require prophylactic central compartment neck dissection (PCND), according to our retrospective study published recently in the Annals of Surgical Oncology . (mskcc.org)
  • New studies could suggest that CN dissection is not performed for low-risk PTCs in UPTs. (tubitak.gov.tr)
  • 5% risk of PLNM by nomograms often receive pelvic lymph node dissection (PLND) during prostatectomy. (lu.se)
  • Objective: Lymph node metastases (pN+) in presumed early-stage cervical cancer negatively impact prognosis. (lu.se)
  • In China, gastric cancer remains a major health risk, ranking the second in cancer incidence and mortality with very poor prognosis [ 1 ]. (biomedcentral.com)
  • Crettenand F, Martin D, Cherix S, Demartines N, Matter M. Occurrence and prognosis of lymph node metastases in patients selected for isolated limb perfusion with soft tissue sarcoma. (jcancer.org)
  • Fibronectin is associated with high-risk breast cancer with poor prognosis. (scienceblog.com)
  • Aoyagi K, Kouhuji K, Miyagi M, Imaizumi T, Kizaki J, Shirouzu K. Prognosis of metastatic splenic hilum lymph node in patients with gastric cancer after total gastrectomy and splenectomy. (wjgnet.com)
  • Actinic keratosis and basal cell carcinoma are easily excised and have a very good prognosis, while cSCC has a poor prognosis, especially if it invades the lymph nodes and adjacent vital structures. (medscape.com)
  • Prognosis depends on the pathological status of the inguinal lymph nodes and whether spread to adjacent structures has occurred. (cancer.gov)
  • Background: Prostate cancer patients with pelvic lymph node metastasis (PLNM) have poor prognosis. (lu.se)
  • Machine learning predicts the prognosis of breast cancer patients with initial bone metastases. (cdc.gov)
  • Patients with high PDGF-CC had inferior prognosis (P = 0.04) in terms of 5-year DRFi, whereas PDGFRα was up-regulated in lymph node metastasis and recurrences compared to primary tumours. (lu.se)
  • Risk factors for lymph node metastasis in cutaneous squamous cell carcinoma: a long-term retrospective study of Japanese patients. (qxmd.com)
  • The aim of this study was to compare diffusion-weighted magnetic resonance imaging (DWI) with computed tomography perfusion (CTP) for preoperative detection of metastases to lymph nodes (LNs) in head and neck squamous cell carcinoma (SCC). (hindawi.com)
  • Preoperative imaging for high-risk cutaneous squamous cell carcinoma (HRcSCC) of the head and neck lacks robust diagnosis-specific data regarding utility and lacks established guidelines regarding indications. (ahns.info)
  • This article addresses the role of radiation therapy in the management of patients with squamous cell carcinoma metastases of the head and neck . (medscape.com)
  • Previous reports either described MLN metastases of PCa occurring in sentinel lymph node scintigraphy or as a random result during anterior rectal resection in patients with rectal cancer ( 16 - 19 ). (frontiersin.org)
  • Along with well known risk factors for sentinel lymph node (SLN) metastasis in cutaneous melanoma, heavy pigmentation might independently predict SLN positivity and be associated with poor recurrence-free survival. (wiley.com)
  • Wider margins are discouraged because of their potential to interfere with lymphatic mapping and sentinel lymph node biopsy. (medpagetoday.com)
  • In conclusion, accumulating studies have focused on whether we can spare patients from ALND based on the results of sentinel lymph node biopsy (SLNB). (biomedcentral.com)
  • This prospective cohort study aimed to analyze the accuracy of magnetic resonance imaging (MRI) and hysteroscopic excisional biopsy (HEB) for predicting the low- and high-risk patients with endometrial carcinoma for nodal involvement at preoperative evaluation. (nih.gov)
  • Summary Background Data: The SLN is the only involved axillary lymph node in the majority of the patients undergoing ALND for a positive SLN biopsy. (uniba.it)
  • Conclusions: Patients with the most favorable combination of predictive factors still have no less than 13% risk for nonsentinel lymph node metastases and should be offered completion ALND outside of clinical trials of SLN biopsy without back-up axillary clearing. (uniba.it)
  • Node sampling is the definitive method of differentiating benign LNs from metastatic LNs, but biopsy methods are invasive and operator-dependent, with a high incidence of false-negative results [ 4 , 5 ]. (hindawi.com)
  • If there is a palpable regional lymph node on physical exam, imaging should be performed with the plan for a fine needle aspiration biopsy to determine the presence of regional metastatic disease. (ahns.info)
  • Nodal involvement confirmation may be either histological eg, biopsy or by imaging PET CT, CT or MRI with pathological lymph node size defined by a short axis diameter of 10 mm axial plane. (who.int)
  • A lymph node biopsy is the removal of lymph node tissue for examination under a microscope. (medlineplus.gov)
  • A lymph node biopsy is often done in an operating room in a hospital or at an outpatient surgical center. (medlineplus.gov)
  • An open biopsy is surgery to remove all or part of the lymph node. (medlineplus.gov)
  • For some cancers, a special way of finding the best lymph node to biopsy is used. (medlineplus.gov)
  • A needle biopsy involves inserting a needle into a lymph node. (medlineplus.gov)
  • This type of biopsy can be performed by a radiologist with local anesthesia, using ultrasound or CT scan to find the node. (medlineplus.gov)
  • If a lymph node biopsy does not show any signs of cancer, it is more likely that other lymph nodes nearby are also cancer-free. (medlineplus.gov)
  • Twelve PCa patients with biochemical recurrence (BCR) after primary therapy who prospectively underwent a baseline 68 Ga-PSMA-PET/CT initially showed MLN metastases. (frontiersin.org)
  • PET imaging of CA125 expression by ovarian cancer cells may enhance the evaluation of the extent of disease and provide a roadmap to surgery as well as detect recurrence and metastases. (snmjournals.org)
  • A number of established nomograms are available to screen lymph node metastasis (LNM), recurrence, overall survival and cancer-specific survival rates in patients with EC ( 5 , 6 ). (spandidos-publications.com)
  • Lymph node recurrence was documented by positron emission tomography/computed tomography (PET/CT) scan using either C-11-choline or Ga-68 prostate-specific membrane antigen ligand. (uni-koeln.de)
  • Biochemical Recurrence and Risk of Mortality Following Radiotherapy or Radical Prostatectomy. (urotoday.com)
  • Biochemical recurrence in patients with prostate cancer after primary definitive therapy: treatment based on risk stratification. (urotoday.com)
  • Finally, the A1298Cpolymorphism is significantly associated with increased recurrence risk of lymph node-positive breast cancer. (medsci.org)
  • High-risk" features of cSCC are defined as those that are associated with increased risk of recurrence, increase risk of regional and/or distant metastasis, and/or increased risk disease-specific death. (ahns.info)
  • High primary tumour PDGFRα was associated with increased risk of central nervous system (CNS) recurrence. (lu.se)
  • Conclusions: High PDGFRα and PDGF-CC expression were linked to breast cancer with an aggressive biological phenotype, e.g. the TNBC subtype, and high PDGF-CC increased the risk of 5-year distant recurrence. (lu.se)
  • a) Malignancy treated with curative intent with no known active disease =2 years before the first dose of study intervention and of low potential risk for recurrence. (who.int)
  • Table 3 Multivariate analysis of lymph node metastases in early gastric malignancy for the entire study population Relationship between depth of invasion and quantity of metastatic lymph nodes There was no significant difference between mucosal and submucosal tumors in terms of quantity of retrieved lymph nodes, using the self-employed sample test (= 0.350, df = 200, = 0.727, mean difference = 0.534). (bioskinrevive.com)
  • The number of metastatic lymph nodes in those with mucosal tumors was slightly higher than in those with. (bioskinrevive.com)
  • All 8 EBV-GCLSs occurred in male patients and invaded deep submucosa (SM2) without lymph node metastasis (LNM), four (50%) of which had synchronous non-gastric malignant tumors (3 gastric gastrointestinal stromal tumors and 1 primary clear cell renal cell carcinoma), and four (50%) arose in the proximal stomach. (biomedcentral.com)
  • Methods: All the axillary sentinel and nonsentinel lymph nodes of 1228 patients were reviewed histologically and reclassified according to the current TNM classification of malignant tumors as bearing isolated tumor cells only, micrometastases, or (macro)metastases. (uniba.it)
  • The prevalence of metastases in nonsentinel lymph nodes was correlated to the type of SLN involvement and the size of the metastasis, the number of affected SLNs, and the prospectively collected clinicopathologic variables of the primary tumors. (uniba.it)
  • Ex vivo analysis of tumors and lymph nodes was performed via autoradiography, histopathology, and immunohistochemistry. (snmjournals.org)
  • Our imaging technology has the potential to differentiate aggressive tumors from low-risk tumors. (scienceblog.com)
  • The researchers collected images depicting metastases where breast cancer had spread beyond the original tumors. (scienceblog.com)
  • This allows cells to form tumors in a new location (metastasis). (healthline.com)
  • Tumors arising from some sites (eg, oral tongue) may occasionally skip level II lymph nodes and metastasize to level III or IV lymph nodes. (medscape.com)
  • Presence of lymphatic invasion and deep stromal involvement appeared to be the risk factors for lymph node metastasis of well-differentiated villoglandular adenocarcinoma. (nih.gov)
  • Results: In multivariate analysis, further axillary involvement was significantly associated with the type and size of SLN metastases, the number of affected SLNs, and the occurrence of peritumoral vascular invasion in the primary tumor. (uniba.it)
  • A predictive model based on the characteristics most strongly associated with nonsentinel node metastases was able to identify subgroups of patients at significantly different risk for further axillary involvement. (uniba.it)
  • and those with preoperative imaging studies (CT and MRI) for the evaluation of lymph node involvement. (hindawi.com)
  • Lymph node involvement was observed in 13 patients (N1, 23%), regarded as metastatic spreading in 4 angiosarcomas, 3 epithelioid sarcomas, 2 leiomyosarcomas, 2 undifferentiated sarcomas and 2 synovial sarcomas. (jcancer.org)
  • Pathological staging is determined following prostatectomy and depends on factors such as tumor burden, status of surgical margins, extracapsular disease, and seminal vesicle and pelvic lymph node involvement. (medscape.com)
  • Cancer surveillance traditionally is conducted based on tumor anatomic location, histologic features, size, involvement of lymph nodes and distant metastasis (i.e., anatomic stage) at diagnosis. (cdc.gov)
  • Locally recurrent lesions have a higher risk of lymphatic involvement than do untreated lesions. (medscape.com)
  • The prevalence of tumor involvement and the probability of capsular penetration increase with lymph node size. (medscape.com)
  • only participants with lymph node involvement will be included. (who.int)
  • Several prognostic risk factors have been described in the American Joint Committee on Cancer/the Union for International Cancer Control (UICC) 8th edition staging and the Brigham and Women's Hospital T classification system. (qxmd.com)
  • Lymph node metastasis has been proven to be a prognostic factor in EOC [ 8 , 9 ]. (hindawi.com)
  • The presence of multiple metastatic lymph nodes (LNs) is presumed to be a worse prognostic sign [ 3 ]. (hindawi.com)
  • The detection of cervical node metastases provides very important prognostic information and often helps decide the treatment of head and neck SCC. (hindawi.com)
  • We compared the power of gene expression measurements with that of conventional prognostic markers, i.e., clinical, histo- pathological, and cell biological parameters, for predicting distant metastases in breast cancer patients using both established prognostic indices (e.g., the Nottingham Prognostic Index (NPI)) and novel combinations of conventional markers. (lu.se)
  • Rarely, lymph node, lung, or bone metastases cause the presenting symptoms of small thyroid cancers. (msdmanuals.com)
  • The role of single preoperative serum CA-125 levels in predicting pelvic or paraaortic lymph node metastasis in patients operated for epithelial ovarian cancer has been investigated. (hindawi.com)
  • excluding metastasis to pelvic or paraaortic lymph nodes or vagina) prior to CCRT. (who.int)
  • Four of thirteen cases without nodal metastasis were lost to follow-up 36 to 59 months after surgery. (nih.gov)
  • A proof of principle study was undertaken to investigate the relationship between single nucleotide polymorphisms (SNPs) in literature based candidate cancer genes and the risk of nodal metastasis and clinical outcome in endometrioid endometrial cancer (EEC) patients. (wustl.edu)
  • DWI with ADC value measurements may be more accurate than CTP for the preoperative diagnosis of cervical LN metastases. (hindawi.com)
  • Distant metastasis at diagnosis was not an exclusion criterion. (jcancer.org)
  • Detecting High-Risk Factors and Early Diagnosis of Diabetes Using Machine Learning Methods. (cdc.gov)
  • Socioeconomic status, access to care, risk factor patterns, and stage at diagnosis for head and neck cancer among black and white patients. (who.int)
  • However, the prediction of lymph node metastasis by these modalities is not flawless and it is obvious that supplemental methods are required to designate pelvic or para-aortic lymph node metastasis preoperatively [ 8 , 9 ]. (hindawi.com)
  • Yet, to the best of our knowledge, risk prediction nomograms that correctly estimate MI are limited, and the most commonly used and validated nomogram is based on magnetic resonance imaging (MRI) ( 7 ). (spandidos-publications.com)
  • Possible prediction of patterns of cervical lymph node spread based on" by MEHMET ESER SANCAKTAR, GÜLESER SAYLAM et al. (tubitak.gov.tr)
  • The C-indexes of the nomogram for prediction of no ALN metastasis, positive ALN, and four and more ALN metastasis were 0.826, 0.706, and 0.855 in training group and 0.836, 0.731, and 0.897 in validation group. (biomedcentral.com)
  • Computed tomography-based deep-learning prediction of lymph node metastasis risk in locally advanced gastric cancer. (cdc.gov)
  • F, Humphreys K, Easton D, Hall P, Czene K. Prediction of breast cancer risk for sisters of women attending screening. (cancercentrum.se)
  • We used publicly available data on 97 patients, and the performance of metastasis prediction was represented by receiver operating char- acteristic (ROC) areas and Kaplan-Meier plots. (lu.se)
  • Univariate analysis of variance exposed a detailed relationship between the depth of invasion and lymph node metastases at pN1 (= 0.008). (bioskinrevive.com)
  • Diagnostic workup of suspected cSCC will include computed tomography (CT) scanning to evaluate for soft tissue or bony invasion and lymph node metastasis. (medscape.com)
  • For patients with tumor parenchyma ≤ 16.5 mm, the probability of lymph node metastasis is lower and lymph node sampling is feasible. (biomedcentral.com)
  • Therapy is primarily guided by histopathological criteria as the depth of tumor penetration in the submucosa directly correlates with the probability of lymph node metastases. (researchgate.net)
  • A Tool for Predicting an Individual Prostate Cancer Patient's Risk of Metastasis and Need for Lymph Node Irradiation. (manchester.ac.uk)
  • Objectives: The ability to stratify a patient's risk of metastasis and survival permits more refined care. (wustl.edu)
  • Meat consumption and risk of esophageal and gastric cancer in the Golestan Cohort Study, Iran. (who.int)
  • For lymph node metastasis assessment, the majority of studies that evaluate the utility and accuracy of head and neck imaging are in patients with mucosal SCC, not cutaneous SCC. (ahns.info)
  • Most interestingly, activity concentrations greater than 50 %ID/g were observed in the ipsilateral lymph nodes of the xenograft-bearing mice. (snmjournals.org)
  • PCa typically spreads to the proximal external iliac, the lower sacral vessel, the obturator, the upper sacral, the common iliacal and, at last, the paraaortic lymph nodes ( 15 ). (frontiersin.org)
  • Our purpose was to investigate the predictive role of tumor location for lymph node metastasis pattern in PTCs.Materials and methods: Medical records of 110 PTC patients were reviewed retrospectively. (tubitak.gov.tr)
  • Methods: Protein expression of tumour and/or stromal cell PDGFRα, PDGFRβ and PDGF-CC was evaluated in primary tumours (N = 489), synchronous lymph node metastases (N = 135) and asynchronous recurrences (N = 39) using immunohistochemistry in a prospectively maintained cohort of primary breast cancer patients included during 1999-2003. (lu.se)
  • Several studies have demonstrated an advantage of 68 Ga-PSMA-PET/CT as staging modality for detection of prostate cancer (PCa) metastases. (frontiersin.org)
  • The clinical staging of prostate cancer was devised from the American Joint Committee on Cancer (AJCC) tumor, node, metastasis (TNM) system. (medscape.com)
  • Prostate cancer risk stratification is based on groups defined by D'Amico et al in 1998. (medscape.com)
  • Clinical Significance of Radical Prostatectomy in Clinical Lymph Node Metastasis in Prostate Cancer. (urotoday.com)
  • The study aimed to compare the efficacy and safety of androgen deprivation therapy (ADT) with abiraterone or docetaxel versus ADT alone as neoadjuvant therapy in patients with very-high-risk localized prostate cancer. (frontiersin.org)
  • A total of 132 (96.4%) participants had very-high-risk prostate cancer, and 108 (78.8%) had locally advanced disease. (frontiersin.org)
  • Compared with ADT alone, neoadjuvant therapy with ADT plus docetaxel or abiraterone could achieve better pathological outcomes (pCR or MRD) for very-high-risk localized prostate cancer. (frontiersin.org)
  • 2 ] showed a 5-year survival rate between 17% and 55.8% for SCC with cervical node metastases and 44.6-76% for SCC patients without cervical node metastases. (hindawi.com)
  • This study aimed to assess incidence and impact on patient survival based on lymph node metastasis with systematic radical lymphadenectomy during ILP. (jcancer.org)
  • For the N0 patient group, median survival was 73.9 months (CI 95% 41.9-105.9) compared to 15.1 months (CI 95% 7.4-22.6) in case of metastatic lymph node ( p =0.002). (jcancer.org)
  • Lymph node metastases of STS patients selected for ILP seemed to have a negative impact on both overall and disease-free survival. (jcancer.org)
  • The study aim was to assess incidence and impact on patient survival of lymph node metastases in limb STS during ILP with systematic radical lymphadenectomy. (jcancer.org)
  • However, many studies have reported that lymphadenectomy is associated with increased morbidity and no survival benefit in low-risk EC patients [ 6 - 8 ]. (medsci.org)
  • However, within and across cancers, biomarkers can identify heterogeneous subgroups associated with different risk factors, treatment responses, recurrences and survival patterns. (cdc.gov)
  • In paediatrics, papillary thyroid cancer-specific 30-year survival is approximately 99-100% irrespective of sex or presence of regional lymph node metastasis at presentation, with a minimal decrease in survival (to 97%) for patients with distant metastasis. (who.int)
  • Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival. (cancercentrum.se)
  • In individuals with submucosal cancers, the lymph node metastases rate in individuals with venous invasion (60%, 3/5) was higher than in those without invasion (20%, 15/75) (2 = 4.301, = 0.038). (bioskinrevive.com)
  • In individuals with submucosal cancers, there was no significant difference in the event of lymph node metastases in relation to sex, age, tumor location, tumor size, quantity of retrieved lymph nodes, morphological classification, histological type, lymphatic invasion, nervous invasion and CEA levels. (bioskinrevive.com)
  • Patients with endometrioid uterine cancers with no myometrial invasion and tumor grade I/II might have minimal risk of LNM, whereas others might require complete pelvic and para-aortic lymphadenectomy for surgical staging. (korea.ac.kr)
  • Can CA-125 Predict Lymph Node Metastasis in Epithelial Ovarian Cancers in Turkish Population? (hindawi.com)
  • Although CA-125 in epithelial ovarian cancers, which varies extensively depending on racial and genetic differences, has been studied extensively, the effect of preoperative CA-125 levels in predicting lymph node metastases is controversial. (hindawi.com)
  • Increasing age is the most important risk factor for most cancers. (cancer.gov)
  • However, whether these inflammatory laboratory parameters have a predictive effect on the metastasis of NSCLC lymph nodes has been rarely reported. (biomedcentral.com)
  • According to our data analysis, the integration of MRI and HEB showed an elevated accuracy and high rates of sensitivity (85.0%), specificity (88.5%), negative predictive value (91.9%) and positive predictive value (79.0%) in identifying low-risk patients who do not need comprehensive surgical staging. (nih.gov)
  • The tumor marker CA-125, which increases with grade independent of the effect of stage in EOC, is predictive of lymph node metastasis with a high rate of false positivity in Turkish population. (hindawi.com)
  • Besides the known oncological benefits of ADT and sRT, in case of sole MLN metastases individualized therapy like salvage lymphadenectomy or RT with a defined radiation field could be options for these patients. (frontiersin.org)
  • Lymph node metastasis rate detected by systematic lymphadenectomy has been notified as 44% to 53% in unselected series containing all FIGO stages [ 6 , 7 ]. (hindawi.com)
  • In the past, a full lymphadenectomy, including the pelvic and para-aortic nodes, was recommended in all patients with EC. (medsci.org)
  • Histopathologic analysis of the immuno-PET-positive lymph nodes revealed the presence of grossly metastasized ovarian cancer cells within the lymphoid tissues. (snmjournals.org)
  • If the metastatic nodes significantly obstruct the lymphatic trunks, patients who have clinically positive lymph nodes on the ipsilateral side of the neck may be at risk for contralateral lymph node spread. (medscape.com)
  • It is difficult to determine the lymph node metastasis of patients with clinically negative lymph nodes (cN0) non-small cell lung cancer (NSCLC) before surgery. (biomedcentral.com)
  • Table 1 shows the estimated risk of subclinical disease in patients with clinically negative neck findings as a function of primary site and T stage. (medscape.com)
  • We applied privacy-preserving federated logistic regression to identify risk factors of pN+. (lu.se)
  • Significant factors were used to stratify the risk of pN+. (lu.se)
  • Risk factors for metastases should be considered when choosing surgery for EGC. (bioskinrevive.com)
  • RESULTS Univariate analysis of lymph node metastases in EGC and clinicopathological factors Univariate analysis was performed on the relationship between lymph node metastases and clinicopathological factors. (bioskinrevive.com)
  • This study aimed to identify factors that could predict lymph node metastasis in Asian patients. (qxmd.com)
  • Five factors were evaluated for their ability to predict lymph node metastasis: maximum tumor diameter, tumor thickness, depth of invasion, degree of differentiation, and infiltrative growth pattern (INF). (qxmd.com)
  • Risk factors of occult lymph node metastasis of levels â ¢ and â £ in papillary thyroid carcinoma]. (bvsalud.org)
  • Binary logistic regression analysis was applied to predict risk factors for lymph node metastasis, and subject operating characteristics (ROC) curve was used to evaluate the independent risk factors. (biomedcentral.com)
  • 0.001) and preoperative serum carcinoembryonic antigen (CEA) level (p = 0.017) are independent risk factors lymph node metastasis in cN0 NSCLC. (biomedcentral.com)
  • This study aims to investigate the factors that can predict cN0 NSCLC lymph node metastasis, including basic characteristics of patients, imaging characteristics and preoperative examination of some hematological indicators. (biomedcentral.com)
  • Risk factors for LNM were identified by using logistic regression model. (clinicsofoncology.org)
  • Knowledge of the risk factors for lymph node metastasis (LNM) is necessary to treat patients with endometrioid uterine cancer to optimize and further individualize treatment. (korea.ac.kr)
  • Certain risk factors make a person more likely to have a malignant lymph problem, such as lymphoma. (medicalnewstoday.com)
  • All local treatment of early colorectal cancer must be critically weighed against radical surgery taking individual patient risk factors into consideration. (researchgate.net)
  • A nomogram was then constructed based on the independent risk factors identified. (spandidos-publications.com)
  • A nomogram was generated to predict a patient's probability of MI based on the four independent risk factors. (spandidos-publications.com)
  • Metabolic syndrome (MetS) represents a cluster of cardiovascular risk factors, including elevated blood pressure, obesity, high circulating triglyceride (TG), dysglycemia and low circulating high-density lipoprotein cholesterol (HDL-C). One study indicated that EC is a form of cancer that has associations with metabolic diseases, and that EC incidence increases with metabolic disease prevalence ( 8 ). (spandidos-publications.com)
  • Nerve injury can occur even in diabetic patients, whose blood glucose is well controlled and have no other risk factors. (magiran.com)
  • The aim of present study was to investigate the incidence, trend and risk factors of melanoma in Iranian childhood and adolescents. (magiran.com)
  • Certain factors may increase your risk of developing the disease, including some inherited conditions. (healthline.com)
  • This study was aimed to establish the nomogram to predict patients' axillary node status by using patients' clinicopathological and tumor characteristic factors. (biomedcentral.com)
  • We successfully construct and validate the nomogram to predict patients' axillary node status by using patients' clinicopathological and tumor characteristic factors. (biomedcentral.com)
  • We performed logistic regression analysis to determine which clinicopathological characteristics were the risk factors for positive LVSI status and to estimate the odds ratio (OR) for each covariate. (medsci.org)
  • Using the risk factors and OR identified through this process, we created a model that could predict LVSI and analyzed it further using receiver operating characteristic curve analysis. (medsci.org)
  • 0.001), and presence of cervical stromal invasion (P = 0.002) were identified as the risk factors for LVSI. (medsci.org)
  • Risk factors include ultraviolet (UV) light exposure and immunosuppression. (logicalimages.com)
  • Foreign bodies, such as tattoo ink, have also been identified as risk factors for keratoacanthomas. (logicalimages.com)
  • 18. For patients who presented biochemical relapse after radical prostatectomy, which of the following factors are related more to local relapse than to remote metastasis? (imop.gr)
  • Brigham and Womens' stage T2b (defined as 2-3 of the following risk factors: tumor diameter ≥ 2 cm, poorly differentiated histology, depth of tumor invasion beyond fat, and/or perineural invasion ≥ 0.1 mm) has been shown to have a 21-30% risk of regional micrometastases, thereby indicating a significant risk for occult metastasis. (ahns.info)
  • Age and gender, diet and weight are risk factors for developing breast cancer. (who.int)
  • However, in 70% of breast cancer patients no risk factors can be identified. (who.int)
  • Aims: A clinical model to individually predict the risk of lymph node metastasis (LNM) for young colon cancer (CC) patients will be attractive in current clinical practice. (clinicsofoncology.org)
  • A model to predict the status of nonsentinel axillary lymph nodes could help tailor surgical therapy to those patients most-likely to benefit from completion ALND. (uniba.it)
  • Cox regression analysis was used to predict the risk of prostate CSM after accounting for several parameters, including the use of additional treatments after sLND. (uni-koeln.de)
  • It is therefore reasonable to dig further into the question if we can find a way to predict the status of axillary lymph nodes for breast cancer patients to avoid SLNB. (biomedcentral.com)
  • Using the modified risk index of LVSI, it is possible to predict the presence of LVSI in women with endometrioid endometrial cancer. (medsci.org)
  • Even after surgery on patients with low-risk papillary thyroid microcarcinoma by well-experienced thyroid surgeons, complications such as temporary vocal cord paralysis, permanent vocal cord paralysis, temporary hypoparathyroidism, permanent hypoparathyroidism developed with the incidence of 4.1%, 0.2%, 16.7% and 1.6%, respectively. (wikipedia.org)
  • Men are more commonly affected than women, individuals with lighter skin phototypes are at greater risk than those with darker skin phototypes, and peak incidence is between 65 and 71 years of age. (logicalimages.com)
  • Preoperative ultrasound and enhanced Computer Tomography (CT) did not denote suspected enlarged lymph nodes in the lateral neck . (bvsalud.org)
  • Swollen lymph nodes, or swollen glands, in the neck may indicate an infection. (medicalnewstoday.com)
  • For example, an ear infection may cause swollen lymph nodes near the ear, while someone with an upper respiratory tract infection may notice swollen lymph nodes in their neck. (medicalnewstoday.com)
  • People can check whether their lymph nodes are swollen by gently pressing around the area, such as the side of the neck. (medicalnewstoday.com)
  • Many different conditions cause the lymph nodes to swell, particularly the nodes in the head and neck. (medicalnewstoday.com)
  • Forty-three patients had central neck metastasis (CNM) and 14 had lateral neck metastasis (LNM). (tubitak.gov.tr)
  • Ultimately, physicians can exercise their own preferences for imaging of patients with HRcSCC in order to evaluate 1) the extent of local invasion, 2) the possibility of regional metastases to the parotid and/or neck, and 3) the presence of distant metastases. (ahns.info)
  • However, one can extrapolate the imaging characteristics of suspicious lymph nodes from head and neck mucosal SCC to cSCC of the head and neck. (ahns.info)
  • 8 A review of 17 studies that each compared imaging assessments of neck lymph nodes to histopathologic findings in patients with head and neck aerodigestive SCC found that CT, MRI, and US all had fairly similar sensitivities, ranging from 80-87%, with US having the highest sensitivity. (ahns.info)
  • The most commonly involved lymph nodes in the head and neck are the subdigastric (level II) lymph nodes, followed by the midjugular (level III) lymph nodes. (medscape.com)
  • Lesions that are well lateralized usually spread first to the ipsilateral neck nodes, while nasopharyngeal lesions and lesions on or near the midline and lateralized base of the tongue may spread to both sides of the neck. (medscape.com)
  • Additionally, patients who have undergone previous surgery on one side of the neck shunt lymph across the submentum to the opposite side of the neck. (medscape.com)
  • Furthermore, prevalence of pelvic or para-aortic lymph node metastasis is higher in EOC when compared with other gynecologic malignancies [ 4 , 5 ]. (hindawi.com)
  • Multivariate logistic regression analysis Selumetinib revealed the depth of invasion was the only self-employed risk element Selumetinib for lymph node metastases in EGC [= 0.018, Exp (B) = 2.744]. (bioskinrevive.com)
  • treatment with radical hysterectomy and pelvic lymph node assessment. (lu.se)
  • Surgery is usually the primary treatment for EC, which consists of total hysterectomy and bilateral salpingo-oophorectomy with lymph node assessment [ 5 ]. (medsci.org)
  • 7 Positron emission tomography (PET)/CT provides additional information about the presence or absence of distant metastases. (ahns.info)
  • 98-100% for localized or regional disease and 85-95% for distant metastases in patients younger than 55 years. (who.int)
  • We look for papers that provide insights into the causes and progression of melanoma, aiming to advance the field and find ways to prevent this type of skin cancer, with a focus on the process of metastasis and invasion, proliferation, senescence, apoptosis or gene regulation. (wiley.com)
  • The original system for describing depth of invasion , Clark levels remain in use as a standardized method to convey melanoma aggressiveness or risk. (medpagetoday.com)
  • Aug. 31, 2023 A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. (sciencedaily.com)
  • Active surveillance is an observational management being increasingly accepted as alternative to immediate surgery for low-risk papillary thyroid microcarcinoma with no evidence of extrathyroidal extension or metastatic spread. (wikipedia.org)
  • His proposal was approved and the study for low-risk papillary microcarcinoma began in the same year. (wikipedia.org)
  • On CTP images, the mean value in metastatic nodes of blood flow (BF) and blood volume (BV) was higher than that in benign nodes, and mean transit time (MTT) in metastatic nodes was lower than that in benign nodes. (hindawi.com)
  • In the cases with lymph node metastasis, adjuvant radiation therapy was also given. (nih.gov)
  • Your doctor may recommend adjuvant chemotherapy if you have a high risk of the cancer recurring or spreading to other parts of your body (metastasizing), even if there is no evidence of cancer after surgery. (drugs.com)
  • The purpose of the current study was to investigate single preoperative serum CA-125 level in predicting lymph node metastases in Turkish patients with EOC. (hindawi.com)
  • Opium use and risk of lung cancer: A multicenter case-control study in Iran. (who.int)
  • Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program. (who.int)