Loading...
  • findings
  • Our goal is to extend the lives of patients with lung cancer, and the unambiguous survival findings from KEYNOTE-189 showing the risk of death was reduced by half in the KEYTRUDA arm are important not only for patients but also for the medical community,' said Dr. Roger M. Perlmutter, president, Merck Research Laboratories. (twst.com)
  • significantly increased
  • Using the 75th percentile TM in the controls as cutoff point, we found that high levels of net BPDE- and γ radiation-induced DNA damage were associated with significantly increased risks of EAC, with adjusted ORs of 2.15 (95% CI, 1.13-4.10) and 2.27 (95% CI, 1.24-4.16), respectively. (omicsonline.org)
  • There was a significantly increased risk associated with adolescent overweight at baseline in the combined group of EAC and GEJAC cases (multivariable hazard ratio, 2.1). (empr.com)
  • cells
  • Recently, bile acids were shown to be able to induce intestinal differentiation, in gastroesophageal junction cells, through inhibition of the epidermal growth factor receptor (EGFR) and the protein kinase enzyme Akt. (wikipedia.org)
  • This mechanism also explains the selection of HER2/neu (also called ERBB2) and the overexpressing (lineage-addicted) cancer cells during the process of carcinogenesis, and the efficacy of targeted therapy against the Her-2 receptor with trastuzumab (Herceptin) in the treatment of adenocarcinomas at the gastroesophageal junction. (wikipedia.org)
  • features
  • Other features that we talk about, other heritable risks, are being MSI high, which is part of Lynch syndrome. (onclive.com)
  • High-Risk
  • Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075). (readbyqxmd.com)
  • Current guidelines recommend an individualized approach to screening with a focus on screening high-risk individuals. (renalandurologynews.com)