Risk factors approaches models cardiovascular. Medical search. Frequent questions

The influence of social and behavioral factors in the work place, or more accurately the composite elements of work ing life on cardio-vascular and other chronic diseases, has influenced several major currents in occupational health research. (cdc.gov)
Environmental factors, including air and noise pollution, and the built environment, are typically associated with cardiovascular and metabolic non-communicable diseases (NCDs), e.g. obesity, type 2 diabetes, heart diseases and atherosclerosis. (europa.eu)
My laboratory is engaged in system biology approaches to investigate cardiovascular diseases. (yale.edu)
Compared to the general population, individuals with depression have an increased risk for cardiovascular diseases. (frontiersin.org)
Projections assume that depression will be the leading cause of disability worldwide by 2030 ( 9 ), which might be partly due to the high comorbidity with cardiovascular diseases (CVDs) ( 10 , 11 ). (frontiersin.org)
Sophia Antipolis, 3 February 2017: Number of children is emerging as a novel factor that influences the risk for some cardiovascular diseases (CVD), and in some societies in both parents, according to Professor Vera Regitz-Zagrosek, chairperson of the European Society of Cardiology "management of CVD During Pregnancy" guidelines task force. (enn.com)
Non-communicable diseases (NCDs) are emerging as the leading cause of death globally and also in the South East Asia region due to many social determinants like unhealthy lifestyles, globalization, trade and marketing, demographic and economic transitions, leading to behavioral and metabolic risk factors. (who.int)
Cardiovascular diseases (CVD), Chronic non-infectious respiratory diseases (like COPD), Cancers and Diabetes Mel itus are referred as essential non-communicable disease with wel established common modifiable risk factors. (who.int)
On the brighter side, major NCD risk factors are behaviorally modifiable and are influenced by socio- economic conditions, making socio-economic factors as both cause and effect of these diseases. (who.int)
Annex 4 to this document sets out the challenges to and opportunities for promoting access to affordable diagnostics, screening and early diagnosis as part of a comprehensive approach to the prevention and control of noncommunicable diseases. (who.int)
A misalignment of this clock occurs due to risk factors linked to AD, such as inflammation, diabetes, sleep disorders, and cardiovascular diseases. (news-medical.net)
Title : A Statistical Model for Assessing Genetic Susceptibility as a Risk Factor in Multifactorial Diseases: Lessons from Occupational Asthma Personal Author(s) : Demchuk, Eugene;Yucesoy, Berran;Johnson, Victor J.;Andrew, Michael;Weston, Ainsley;Germolec, Dori R.;De Rosa, Christopher T.;Luster, Michael I. (cdc.gov)
Cardiovascular diseases (CVD) are a primary source of morbidity and death worldwide, with CAD being one of the most lethal. (news-medical.net)
1 An estimated 7.4 million people in the UK live with cardiovascular diseases, and this is likely to increase with improved survival following coronary heart disease and an ageing population. (bmj.com)
Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO). (nature.com)
We use electronic health record data and genetic data as tools to understand the heterogeneity of the diabetes patient population and variability in response to interventions, to identify novel risk factors for cardiometabolic diseases, and to build risk models optimized to real-world patient populations in health systems. (cuanschutz.edu)
His research focuses on complex policy decisions surrounding the prevention and management of increasingly common, chronic diseases and the life course impact of exposure to their risk factors. (stanford.edu)
Many diseases such as cancer, obesity, type II diabetes and cardiovascular disease are linked to lifestyle factors such as smoking, poor diet and physical inactivity. (bath.ac.uk)
Physical activity plays a significant role, the authors state, for prevention and management of more than 40 diseases beyond cardiovascular disease. (medscape.com)
Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)
In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)

Surgical measures to combat obesity are very effective in terms of weight loss, recovery from diabetes, and improvement in cardiovascular risk factors. (uni-muenchen.de)
The CKM Health construct and PREVENT risk calculator are suggested as a path forward for more holistic patient care to incorporate total CVD risk that includes heart failure as well as guidance on the use of new medications that have been shown to have benefits for reducing risks related to obesity, diabetes and kidney disease, Khan said. (northwestern.edu)
Experience with changing rates of cardiovascular disease, obesity, diabetes and cancer shows this clearly. (biomedcentral.com)
Tobacco use, harmful alcohol use, unhealthy diet as consumption of less fruits and vegetables, high salt and trans-fat consumption, and physical inactivity are the common behaviorally modifiable risk factors of NCDs while overweight and obesity, raised blood pressure, raised blood glucose and abnormal blood lipids are the metabolic risk factors. (who.int)
Three of the top health-related issues affecting adults - asthma, obesity and depression - can be related directly to environmental factors and behaviors. (chausa.org)
Previously reported risks following paralysis include obesity, fasting dyslipidemia and hypertension, among other health issues which include physical deconditioning, postprandial lipemia, and inflammatory vascular stress. (themiamiproject.org)
Amongst various factors, hypercholesterolemia is directly linked with obesity and is the primary trigger of underlying inflammation, insulin resistance, and oxidative stress [ 5 ]. (hindawi.com)
1 The influence of social relationships on mortality is comparable with well-established risk factors, including physical activity and obesity. (bmj.com)
My research interests are focused broadly on precision medicine approaches for preventing and treating obesity, diabetes, and their complications, particularly cardiovascular disease. (cuanschutz.edu)
Incident Type 2 Diabetes Risk is Influenced by Obesity and Diabetes in Social Contacts: a Social Network Analysis. (cuanschutz.edu)

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and has been associated with cardiovascular disease, the leading cause of mortality in diabetes. (springer.com)
This learning collaborative approach illustrates the importance of public health in the prevention and control of chronic disease by supporting interventions that address community and clinical linkages to address medical risk factors associated with cardiovascular disease. (cdc.gov)

Miami Project researchers recently published a manuscript titled, Cardiometabolic risks and atherosclerotic disease in ApoE knockout mice: Effect of spinal cord injury and Salsalate anti-inflammatory pharmacotherapy in the journal PLOS ONE that demonstrates positive results in treating some of the secondary cardiovascular complications following spinal cord injury (SCI). (themiamiproject.org)
These widely reported AD risk factors after SCI raise a fundamental question whether-or to what extent-SCI alters the trajectory of these cardiovascular complications. (themiamiproject.org)
A 5-year effectiveness study of the CCM for 53,436 people with type 2 diabetes found an overall decrease in the cumulative incidence of diabetes-related complications, with people enrolled in the CCM experiencing a reduction in cardiovascular disease risk by 56.6%, microvascular complications by 11.9%, and mortality by 66.1% [7]. (escardio.org)
Describe cardiovascular symptoms and complications associated with post-COVID conditions. (cdc.gov)
Today I'll present an overview of post-COVID conditions as an introduction of the main presentation on evaluating and supporting patients with cardiovascular symptoms and complications following COVID-19. (cdc.gov)
Diabetes is serious due to its complications, namely: cardiovascular ailments, cerebral vascular accidents, renal insufficiency, blindness, sexual impotence and gangrene of the feet leading to amputation. (who.int)
In Paper IV, we conducted a systematic review and metanalysis of observational studies, complemented by Mendelian randomization analysis using GWAS summary statistics, investigating causal associations of individuals with high, yet normal, glycaemia associated with cardiovascular complications. (lu.se)

Up to 40% of the US population will develop type 2 diabetes during their lifetime, and type 2 diabetes is an important contributor to major adverse cardiovascular events (MACE) such as myocardial infarction and stroke-the leading causes of morbidity and mortality in Western countries [ 2 ]. (springer.com)
In addition, while recognized inhaled cardio-toxins are relatively uncommon and contribute modestly to risk, physical and organizational factors such as noise and vibration and shift work emerge as significant predictors of CVD mortality. (cdc.gov)
Moreover, a 2-3 fold CVD mortality-risk in manual work ers compared to administrative work ers in some countries suggests that ecological artifacts may blunt risk associations in work ing cohorts. (cdc.gov)
Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment. (cam.ac.uk)
The goal of CRESSH's research is to understand how simultaneous exposures to multiple chemical stressors and their interactions with non-chemical stressors and social determinants of health lead to environmental health disparities at varying stages of life as measured by birth outcomes, childhood growth trajectories and cardiovascular mortality. (harvard.edu)
Several reasons attributed for the higher affliction rate of CVD, fatal outcomes, and mortality are inherent pathobiological mechanisms, social factors, lifestyle, alcohol abuse (smoking), and their interactions [ 4 ]. (hindawi.com)
Adults who have few social contacts (ie, who are socially isolated) or feel unhappy about their social relationships (ie, who are lonely) are at increased risk of premature mortality. (bmj.com)
Raghavan S, Liu WG, Berkowitz SA, Barón AE, Plomondon ME, Maddox TM, Reusch JEB, Ho PM, Caplan L. Association of Glycemic Control Trajectory with Short-Term Mortality in Diabetes Patients with High Cardiovascular Risk: a Joint Latent Class Modeling Study. (cuanschutz.edu)
Diabetes Mellitus-Related All-Cause and Cardiovascular Mortality in a National Cohort of Adults. (cuanschutz.edu)
Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial. (cuanschutz.edu)
Other clinicians, community leaders, and fitness experts can help get people moving and reduce their risk for morbidity and mortality from conditions associated with physical inactivity. (medscape.com)

The 2014 World Alzheimer Report focused upon dementia risk reduction, examining the evidence base for modifiable risk factors for dementia [ 7 ]. (biomedcentral.com)
Indoor air pol ution is another important modifiable behavioral risk factor for the region and the country. (who.int)
Intensive treatment of modifiable risk factors are recommended for the treatment of PAD, including lifestyle interventions such as smoking cessation and exercise in conjunction with evidence-based pharmacological interventions. (escardio.org)
Although the exact mechanisms behind PA [physical activity] as an independent modifiable risk factor remain incompletely elucidated, strong evidence suggests that regular PA slows and even reverses adverse vascular remodeling associated with aging," the statement authors note. (medscape.com)

This suggests that individuals with a low birth weight may benefit from early targeted cardiovascular disease prevention strategies, independent of whether this was linked to an adverse intrauterine environment during gestation. (imperial.ac.uk)

Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis. (cam.ac.uk)
The WHO/ISH risk prediction charts indicate 10-year risk of a fatal or nonfatal major cardiovascular event (myocardial infarction or stroke), according to age, sex, blood pressure, smoking status, total blood cholesterol and presence or absence of diabetes mellitus for 14 WHO epidemiological sub-regions. (who.int)
We illustrate our approach by modeling the divergence in childhood-to-adulthood body mass index (BMI) trajectories between two groups of adults with/without type 2 diabetes mellitus (T2DM) in the Cardiovascular Risk in Young Finns Study (YFS). (monash.edu)
Dependence counts normalized for non-uniformity, from the neighboring grey level dependence matrix (NGLDM) family and the status of diabetes mellitus from the clinical parameters were most frequently chosen from the stress set for classifying CAD risk. (news-medical.net)
As asymptomatic myocardial ischemia (MI) is frequent in diabetes, we hypothesized that DPN may be associated with MI in patients with type 2 diabetes mellitus and no history of cardiovascular events. (springer.com)
This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. (lu.se)

Only cardiac troponin, and to some degree also B-type natriuretic peptides, is widely used in clinical practice for risk assessment. (degruyter.com)
To validate the model, the team performed the same assessment of blood and feces samples on more than 100 patients in the LIFSCREEN trial who have Li-Fraumeni syndrome, a rare genetic disorder that increases a person's risk for cancer. (medscape.com)
A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples. (cam.ac.uk)
CRESSH is conducting three independent multidisciplinary projects that utilize the expertise of investigators in epidemiology, exposure science and cumulative risk assessment. (harvard.edu)
We will focus on multi-stressor epidemiology for multiple health outcomes across the life course, exposure science addressing indoor-outdoor exposure patterns using novel sensors and modeling techniques, and quantitative approaches for cumulative risk assessment and disparities analyses that leverage epidemiological and exposure insights. (harvard.edu)
Home 1 / ICS Publications 2 / Developing Non-Laboratory Cardiovascular Risk Assessment Charts and Validating. (irancohorts.ir)
Developing simplified risk assessment model based on non-laboratory risk factors that could determine cardiovascular risk as accurately as laboratory-based one can be valuable, particularly in developing countries where there are limited resources. (irancohorts.ir)
To develop a simplified non-laboratory cardiovascular disease risk assessment chart based on previously reported laboratory-based chart and evaluate internal and external validation, and recalibration of both risk models to assess the performance of risk scoring tools in other population. (irancohorts.ir)
Tehran Lipid and Glucose Study (TLGS) data was used to evaluate the external validity of both non-laboratory and laboratory risk assessment models in other populations rather than one used in the model derivation. (irancohorts.ir)
Our simplified risk assessment model based on non-laboratory risk factors could determine cardiovascular risk as accurately as laboratory-based one. (irancohorts.ir)
This approach can provide simple risk assessment tool where laboratory testing is unavailable, inconvenient, and costly. (irancohorts.ir)
Hassannejad R, Mansourian M, Marateb H, Mohebian MR, Gaziano TA, Jackson RT, Angelantonio ED, Sarrafzadegan N. Developing Non-Laboratory Cardiovascular Risk Assessment Charts and Validating Laboratory and Non-Laboratory-Based Models. (irancohorts.ir)
Though traditional markers of cardiovascular risk are still an integral part of initial cardiovascular risk assessment, several additional risk factors have emerged that provide a more complete picture of total risk status. (biomedcentral.com)
These results suggest that DPN assessment could help in identifying patients at risk of cardiovascular disease (CVD). (springer.com)

Clinical decision-making based on overall cardiovascular risk in addition to individual risk factors can improve outcomes, as demonstrated for antihypertensive treatment [ 12 ]. (springer.com)
James Buteau proposes to address both these unmet needs with two first-in-field clinical trials testing PSMA-targeted theranostic approaches. (pcf.org)
Researchers from France are developing a model to find biomarkers and clinical risk factors that can better identify individuals at risk for cancer who should be screened. (medscape.com)
Using machine learning, the team highlighted more than 30 biomarkers and 2 clinical risk factors among patients with cardiovascular disease who smoked and 13 biomarkers and 8 clinical risk factors among patients with Li-Fraumeni syndrome that could effectively identify those at risk for cancer. (medscape.com)
Using machine learning, the researchers found 33 biomarkers and 2 clinical risk factors among patients with cardiovascular disease that led to a cancer risk estimate with an area under the curve (AUC) of 0.78. (medscape.com)
In the cohort of patients with Li-Fraumeni syndrome, 13 soluble markers and 8 clinical risk factors predicted cancer risk with an AUC of 0.82. (medscape.com)
This study, combining biomarkers with clinical risk factors, may prove to be a safe and effective way to identify patients at risk for developing malignancy," said Manley, director, of interventional pulmonology at Fox Chase Cancer Center, Philadelphia. (medscape.com)
Evidence-based life-course causal models will estimate how clinical and policy interventions may sustainably affect the health and economic burden of NCDs. (europa.eu)
Professor, Departments of Neurological Surgery, Physical Medicine & Medicine and Physical Therapy, Co-Director, DHHS-NIDILRR South Florida SCI Model System, and led by Gregory Bigford, Ph.D., Assistant Scientist , discovered these findings in their pre-clinical work, and hope that further study will lead to effective clinical interventions for those living with SCI. (themiamiproject.org)
More recent approaches to AD diagnosis and clinical management have focused on AD as an inflammatory disorder defined by the presence and actions inflammatory biomarkers. (themiamiproject.org)
CONCLUSION: The ability of DL models to exploit site-specific biases as shortcuts raises concerns about their reliability, generalization, and deployability in clinical settings. (bvsalud.org)
Moving from a clinical model of care to a community model of prevention requires a comprehensive approach to community engagement (2-5). (cdc.gov)
Determine which clinical assessments and tests are needed for a patient with cardiovascular symptoms. (cdc.gov)
However, these questions may never be answered because we hope that there will never be another patient with classical smallpox, and the best nonhuman primate model does not perfectly reproduce clinical smallpox. (cdc.gov)
In addition, patients experienced high fever, cardiovascular collapse, and other clinical signs that we now associate with the cytokine cascade. (cdc.gov)
Although multiple animal models are available for mild to moderate clinical disease, models that develop severe disease are still needed. (cdc.gov)
These health agencies implemented public health and clinical interventions in medical settings and health organizations using a logic model and rapid quality improvement process focused on a framework of 4 systems-change levers: 1) data-driven action, 2) clinical practice standardization, 3) clinical-community linkages, and 4) financing and policy. (cdc.gov)

The CNL will determine the relationship between food preferences, consumption patterns and dietary acculturation, and cardiovascular health using population-based datasets by assessing the impact of acculturation status on dietary patterns and health outcomes. (usda.gov)
It also includes a measure of kidney health, which has been recognized more recently as an important risk factor for heart disease that can be managed and treated to improve health outcomes. (northwestern.edu)
Conclusions: BHPR is a powerful analytic tool to model long-term non-linear longitudinal outcomes, enabling the identification of the age at which risk factor trajectories diverge between groups of participants. (monash.edu)
A 2020 European position paper, in keeping with other national and international guidelines, 2 3 stated that "comprehensive cardiac rehabilitation has been recognised as the most cost effective intervention to ensure favourable outcomes across a wide spectrum of cardiovascular disease. (bmj.com)
The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
The purpose of this Funding Opportunity Announcement (FOA) is to stimulate collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity with the primary intent to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
Research examining model calibration and validation, the appropriate representation of uncertainty in projected outcomes, the use of models to examine plausible counterfactuals at the biological and epidemiological level, and the reflection of population and spatial heterogeneity. (stanford.edu)
For optimal deployment of the team there should be a coordinated, systematic approach to care that ensures that dedicated resources are put into the management of all aspects of care required to optimise outcomes for the person living with PAD. (escardio.org)

The increasing rates of cardiovascular disease (CVD) among Hispanics, particularly those living in US-Mexico border communities, are of great public health concern (1). (cdc.gov)

Cardiovascular prevention is further complicated by increased rates of drug side effects in people with diabetes, including potential adverse glycaemic effects of lipid-modifying agents [ 6 , 7 ]. (springer.com)
Identification of high-risk individuals in whom the benefits of aggressive prevention outweigh the costs and side effects is therefore crucial. (springer.com)
If healthcare providers can identify a group at increased risk, then a more concentrated effort can be made for cancer prevention and early detection. (medscape.com)
The update, called PREVENT TM ( Predicting Risk of cardiovascular disease EVENTs ), predicts someone's risk for cardiovascular disease (CVD) better and younger than before, and its race-free approach reflects the need to prioritize health equity when approaching prediction and prevention of CVD, said corresponding study author Dr. Sadiya Khan. (northwestern.edu)
The new equations help incorporate cardiovascular-kidney-metabolic (CKM) syndrome into CVD prevention. (northwestern.edu)
To address cardiovascular disease risk factors among Hispanics, a community model of prevention requires a comprehensive approach to community engagement. (cdc.gov)
Community health promotion and disease prevention models are needed to compensate for the large number of uninsured, underinsured, and disadvantaged people living in these communities. (cdc.gov)
Page 2 of 9 year initiative introducing community-based participatory research (CBPR) to engage academia and communities in setting up programs with an ecological approach to health promotion and disease prevention. (cdc.gov)
The environmental restructuring is designed to promote community use of existing physical activity and nutrition facilities and to integrate promotores into public-sector settings such as public parks, to address cardiovascular health promotion and CVD prevention. (cdc.gov)
Because dietary factors 'contribute substantially to the burden of preventable illness and premature death in the United States,' the national health promotion and disease prevention objectives encourage schools to provide nutrition education from preschool through 12th grade (1). (cdc.gov)
Applying this model to child abuse prevention, we can start with a similar preventive framework to identify families' social stressors, refer them to community supports, and offer suggestions to support a family before there's a crisis," he said. (texmed.org)
Combatting child abuse and neglect through prevention has become a more prevalent approach over the last decade, Dr. Greeley says. (texmed.org)
I'm Commander Ibad Khan, and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)

AIMS: To examine the relevance of genetic and cardiovascular magnetic resonance (CMR) features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD). (imperial.ac.uk)
In a recent study published in Scientific Reports , researchers investigated the performance of a machine learning (ML)-based model in evaluating radiomic features to diagnose coronary artery disease (CAD) and its susceptibility using myocardial perfusion imaging (MPI) single-photon emission computed tomography (SPECT) images. (news-medical.net)

The AHA includes a physically active lifestyle as one of seven factors in their My Life Check - Life's Simple 7 interventions to reduce risk for cardiovascular disease and to improve overall health. (medscape.com)

3. Identify novel biomarkers for food and nutrient intake related to dietary patterns and cardiovascular health. (usda.gov)
3.1 - Effect of a comprehensive 12 month approach to family weight management on biomarkers of dietary intake and cardiometabolic risk factors in child-mothers/female guardian pairs. (usda.gov)
3.2 - Novel nutrient biomarkers to predict risk of heart failure. (usda.gov)
In addition, the CNL will identify and adjudicate novel biomarkers for food and nutrient intake and merge them with established biomarkers thereof, and assess potential relationships with family-wide CVD risk and weight management, and heart failure risk. (usda.gov)
We identified eight protein biomarkers, four of which are novel, for risk of MACE in community residents with type 2 diabetes, and found improved risk prediction by combining multiplex proteomics with an established risk model. (springer.com)
The integration of these inflammatory biomarkers into traditional lipid prediction models may improve the forecasting of future AD. (themiamiproject.org)
In this paper we investigate the use of the joint model framework with a random intercept association structure as an approach to adjust for measurement error, inherent in biomarkers such as SBP. (biomedcentral.com)

Multiplex proteomics could improve understanding and risk prediction of major adverse cardiovascular events (MACE) in type 2 diabetes. (springer.com)
This study assessed 80 cardiovascular and inflammatory proteins for biomarker discovery and prediction of MACE in type 2 diabetes. (springer.com)
Multiprotein arrays could be useful in identifying individuals with type 2 diabetes who are at highest risk of a cardiovascular event. (springer.com)
Diabetes is one of the strongest risk factors for MACE [ 3 ], and one major treatment goal in type 2 diabetes is to prevent MACE. (springer.com)
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose. (cuanschutz.edu)
Metabolic factors and genetic risk mediate familial type 2 diabetes risk in the Framingham Heart Study. (cuanschutz.edu)

Because CPH-NEW is sponsoring a cardiovascular disease and stroke education and outreach population and is undertaking an intervention among Corrections Officers, a group with many stress related concerns, the issues around work place interventions and CVD are cogent. (cdc.gov)
Transesophageal Echocardiography in Cryptogenic Stroke and Patent Foramen Ovale: Analysis of Putative High-Risk Features From the Risk of Paradoxical Embolism Database. (cam.ac.uk)
P = .031), smaller chamber volumes, and lower stroke volume, but higher contractility.ConclusionsThe results of this study support a causal role of low birth weight in cardiovascular disease, even after accounting for the influence of the intrauterine environment. (imperial.ac.uk)
The new model can predict risk of heart disease beginning 10 years younger than before (now at age 30), and estimates someone's risk of total heart disease, which newly includes heart failure, in addition to heart attack and stroke. (northwestern.edu)
By directly modelling the longitudinal component we reduce bias in the hazard ratio for the effect of baseline SBP on the time-to-stroke, showing the large potential to improve on previous prognostic models which use only observed baseline biomarker values. (biomedcentral.com)
A joint model of longitudinal and survival data allows us to investigate the relationship between a repeatedly measured biomarker, subject to measurement error, such as SBP, and the time to an event of interest, such as time to non-fatal stroke. (biomedcentral.com)
Poor social relationships were associated with a 29% increase in risk of incident CHD (pooled relative risk: 1.29, 95% CI 1.04 to 1.59) and a 32% increase in risk of stroke (pooled relative risk: 1.32, 95% CI 1.04 to 1.68). (bmj.com)
Conclusions Our findings suggest that deficiencies in social relationships are associated with an increased risk of developing CHD and stroke. (bmj.com)
The model of cardiac rehabilitation can also be applied to improve functional status of stroke patients, and this is an emerging area of interest supported by the shared pathophysiology and risk factors of cardiovascular conditions. (elsevierpure.com)
The importance of physicians promoting physical activity for patients to prevent or ameliorate the risk for stroke , Alzheimer's disease , cardiovascular disease, and many other conditions has been promulgated by medical societies and researchers for years. (medscape.com)
The association also promotes physical activity as part of its 2020 Impact Goals to improve cardiovascular health and reduce deaths caused by stroke and cardiovascular disease. (medscape.com)

The new PREVENT risk calculator enables clinicians to quantify a person's risk of CVD and may help people receive preventive care or treatment earlier to reduce CVD risk," said Khan, the Magerstadt Professor of Cardiovascular Epidemiology and an associate professor of medicine (cardiology) and preventive medicine (epidemiology) at Northwestern University Feinberg School of Medicine and a Northwestern Medicine preventive cardiologist. (northwestern.edu)

This model will use data including age, PSA, DRE findings, prostate volume, and whole gland Micro-Ultrasound images to risk stratify patients following PSA screening. (pcf.org)
If successful, this project will improve understanding of tumor visibility by Micro-Ultrasound, and result in a 3-minute prostate scan and urine sample test that identifies patients at risk for prostate cancer and improves decisions on whether patients should undergo prostate biopsy or not. (pcf.org)
There is a need for improved therapeutic approaches for patients with advanced metastatic castration-resistant prostate cancer (mCRPC), whilst on the other extreme, there is a need to accurately identify clinically significant prostate cancer in individuals presenting with elevated PSA levels or inconclusive MRI results. (pcf.org)
In the study, Fidelle and colleagues first analyzed data in approximately 500 patients from the PREVALUNG trial , which included current or former smokers with cardiovascular disease who were part of a lung cancer screening program. (medscape.com)
This review examined the approaches used for CVD risk assessments in CKD patients using the concept of integrated risk factors. (minervamedica.it)
Furthermore, this review provided insights into novel artificial intelligence methods, such as machine learning and deep learning algorithms, to carry out accurate and automated CVD risk assessments and survival analyses in patients with CKD. (minervamedica.it)
Therefore, we examined whether common physiological cardiovascular risk factors differ between patients with depression and healthy (non-depressed) controls, whether patients and controls differ in CRF, and whether higher CRF is associated with a lower cardiovascular risk in both patients and healthy controls. (frontiersin.org)
Additionally, we examined whether within the patient sample, cardiovascular risk factors differ between patients with mild, moderate and severe depression, and whether the relationship between symptom severity and cardiovascular risk is moderated by patients' CRF levels. (frontiersin.org)
Compared to healthy controls, patients with depression had a higher cardiovascular risk as evident from about half of the examined indicators. (frontiersin.org)
Few differences in risk markers were found between patients with mild, moderate and severe depression, and no interaction occurred between depression severity and CRF. (frontiersin.org)
Patients with depression and healthy controls differ in several cardiovascular risk markers, putting patients at increased risk for CVDs. (frontiersin.org)
In contrast, people with good CRF show more favourable cardiovascular risk scores, a relationship which was observed in both healthy controls and patients with depression. (frontiersin.org)
Lifestyle interventions targeting healthy diet and/or physical activity are recommended as a physically active and healthy lifestyle contributes equally to patients' mental well-being and cardiovascular health. (frontiersin.org)
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. (bmj.com)
In particular, as a prognostic model for future patients, we describe how this framework can be used to predict survival for new patients who will only have baseline measurements. (biomedcentral.com)
CONCLUSION: The developed CNN model, trained on a large heterogenous database, was able to differentiate PD patients from HC subjects with high accuracy with clinically feasible classification explanations. (bvsalud.org)
The MDVIP model allows us the time to work with our patients as a team to help meet their needs and work closely with specialists and alternative practitioners in arranging their care. (mdvip.com)
The non-laboratory model was in agreement and classified high risk and low risk patients as accurately as the laboratory one. (irancohorts.ir)
Therefore, early identification of patients with DM at high risk for asymptomatic MI consists of a significant challenge. (springer.com)
This association could provide additional information on the link between the risk of cardiovascular disease (CVD) and T2DM, and be useful to better identify patients at risk of MI. (springer.com)
This Funding Opportunity Announcement (FOA) encourages collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity. (nih.gov)
Hannah Fung - a PhD candidate in biology at the School of Humanities and Sciences and a member of the SHP COVID modeling team - talks to us about a new study that shows 17% of COVID-19 patients pass the virus onto others in their households. (stanford.edu)

LONGITOOLS will also allow researchers and policy makers to generate new knowledge - identifying the likely causal (direct and indirect) mechanisms through which exposures to man-made environmental factors affect the risk of NCDs. (europa.eu)
Therefore, NCDs are preventable or their onset can be delayed if underlying socio- economic determinants and behavioral risk factors are addressed in a multisectoral strategic long term wel executed action plans. (who.int)
A multisectoral national integrated NCD and risk factor policy/plan that addresses the 4 main NCDs and their main risk factors. (who.int)

He combines simulation modeling methods and cost-effectiveness analyses with econometric approaches and behavioral economic studies to address these issues. (stanford.edu)
Model-based cost-effectiveness analyses and costing methods studies that examine policy issues relating to cervical cancer screening and human papillomavirus vaccination in countries including the United States, Brazil, India, Kenya, Peru, South Africa, Tanzania, and Thailand. (stanford.edu)
Using structural equation modelling, the mediation analyses enhanced with Mendelian randomization analysis, showed a likely causal putative association between carbohydrate intake and T2D. (lu.se)

However, since these conventional models were developed for a specific cohort with a unique risk profile and further these models do not consider atherosclerotic plaque-based phenotypes, therefore, such models can either underestimate or overestimate the risk of CVD events. (minervamedica.it)
There is a growing realization that traditional risks for atherosclerotic disease may not appropriately predict emergent disease in people living with SCI, due to the complex and robust effects of injury on multiple organ systems. (themiamiproject.org)
Chronic SCI results in a greater prevalence of risk factors for cardiovascular disease (CVD) and atherosclerotic disease (AD) - plaque buildup in a person's arteries - when compared to the able-bodied population. (themiamiproject.org)
These findings suggested that CA is an effective treatment approach for preventing atherosclerotic lesion progression attributed to protection against oxidative stress and various enzymatic activities in the Ath model. (hindawi.com)
At present, cardiovascular origin disorders such as atherosclerotic cardiovascular disease (ASCVD) are the chief reason of illness and death across the globe [ 1 ]. (hindawi.com)

Current projections of the scale of the coming dementia epidemic assume that the age- and sex-specific prevalence of dementia will not vary over time, and that population ageing alone (increasing the number of older people at risk) drives the projected increases. (biomedcentral.com)
There is some evidence to suggest increasing prevalence in East Asia, consistent with worsening cardiovascular risk factor profiles, although secular changes in diagnostic criteria may also have contributed. (biomedcentral.com)
In a recent systemic review looking at global prevalence and risk factors of PAD, diabetes ranked next to smoking, followed by hypertension and hyperlipidaemia, as major risks for PAD [4]. (escardio.org)

In general, CVD risk assessments are performed using conventional risk prediction models. (minervamedica.it)
Assessing Risk Prediction Models Using Individual Participant Data From Multiple Studies. (cam.ac.uk)
Both non-laboratory and laboratory risk prediction models showed good discrimination in the external validation, with Harrell's C of 0.77 (95% CI 0.75-0.78) and 0.78 (95% CI 0.76-0.79), respectively. (irancohorts.ir)

2. Determine the relationship between food preferences, consumption patterns and dietary acculturation, and cardiovascular health using population-based datasets. (usda.gov)
Why is cardiovascular disease a problematic issue for many occupational safety and health investigators? (cdc.gov)
Nevertheless, this integration of contextual and life history factors as critical components of work place associated CVD is not, however, without controversy and presents particular challenges to many occupational health investigators. (cdc.gov)
and perceived quality of life factors [physical health, psychological wellbeing, social relationships and environmental conditions] were assessed using a sample of 698 male automotive assembly workers in Malaysia. (biomedcentral.com)
A risk calculator uses health, demographic and/or socioeconomic information in equations to calculate a risk estimate or score. (northwestern.edu)
There is an opportunity for the current definition of sustainability to be expanded beyond technical materials and methods that protect natural resources to include a holistic approach supporting and improving human health. (chausa.org)
Though the newest version of the LEED program has a focus on improved indoor air quality and reduced use of harmful building materials, LEED ratings do not address many important factors relating to human health such as social connectedness and physical activity. (chausa.org)
Country is implementing NCD risk factor surveys including WHO STEPS survey (3 modules) or health examination survey every 5 years. (who.int)
These models are useful when participants in a prospective cohort study are grouped according to a distal dichotomous health outcome. (monash.edu)
Background The influence of social relationships on morbidity is widely accepted, but the size of the risk to cardiovascular health is unclear. (bmj.com)
3 , 4 Health-risk behaviours associated with loneliness and social isolation include physical inactivity and smoking. (bmj.com)
Our researchers from the Department for Health work to understand the various factors that lead to overall health and wellbeing. (bath.ac.uk)
Research is conducted into these health and disease risk factors in order to inform policy decision making and/or individual lifestyle choices. (bath.ac.uk)
Other long-term health conditions such as permanent disability or aging-related illness require alternative approaches involving evidence-based support to manage ongoing physical challenges. (bath.ac.uk)
The chronic care model (CCM) is a widely adopted approach aimed at providing optimal care for people living with long-term conditions whilst redefining roles of the health care team and empowering self-management of people with diabetes [6]. (escardio.org)
Up until now the approach has not been standardized," lead statement author, Felipe Lobelo, MD, PhD, chair of the AHA Physical Activity Committee of the Council on Lifestyle and Cardiometabolic Health, told Medscape Medical News . (medscape.com)
In our work, we aim to improve the identification of individuals at-risk of cardiometabolic disease through the characterization of complex environmental exposures (i.e. diet, physical activity), that temporally vary, and the health effects on cardiometabolic traits and disease. (lu.se)
Design/methodology/approach: This need can be universally met through the functional role of 'Historian,' a term specific to ICS, or in the case of public health response, incident management system (IMS). (cdc.gov)

Owing to the absence of a control group, we employed a Bayesian structural forecasting model to construct a synthetic control. (uni-muenchen.de)
Background: Bayesian hierarchical piecewise regression (BHPR) modeling has not been previously formulated to detect and characterise the mechanism of trajectory divergence between groups of participants that have longitudinal responses with distinct developmental phases. (monash.edu)

The objectives of phase 2 are 1) to reduce CVD risk factors among Hispanics and 2) to engage the community in an environmental restructuring initiative that focuses on nutrition and exercise. (cdc.gov)

The current study identifies progressive circadian disruptions in the APP23 transgenic (TG) mouse model of AD, which exhibit altered behavioral circadian rhythms, excessive wakefulness, and hyperactivity. (news-medical.net)
Several AD mouse models revealed reduced orexin and its receptors, which leads to sleep disturbances and behavioral issues. (news-medical.net)

The joint modelling of longitudinal and survival data is a valid approach to account for measurement error in the analysis of a repeatedly measured biomarker and a time-to-event. (biomedcentral.com)
A joint model of longitudinal and survival data consists of two component submodels: the longitudinal submodel and the survival submodel. (biomedcentral.com)
The longitudinal submodel allows us to model the trajectory of a repeatedly measured biomarker over time, adjusting for baseline covariates. (biomedcentral.com)
simulated single free Designing measurement in longitudinal multiplicative models: certain vector and Southern models. (scoutconnection.com)

Diet and lifestyle play a crucial role in the progress of some cardiovascular disorders (CVDs). (hindawi.com)
Western-type diets) for chronic periods are associated with the amplification of risk of CVDs. (hindawi.com)
One of the most common causes of CVDs is hypercholesterolemia, and an increase in serum LDL-C and TC are the most important risk factors for the development of inflammatory insult, damage to the vessel wall, platelet activation, and subsequent progression of atherosclerosis [ 6 ]. (hindawi.com)

However, to fully understand the complex physiology and pathophysiology requires the application of tracer methodology and mathematical modelling. (portlandpress.com)

This review highlights the link between eGFR reduction and that of atherosclerosis progression, which increases the risk of adverse cardiovascular events. (minervamedica.it)

In many ways, physicians take the same approach with ailments like cardiovascular disease, says Roberto Rodriguez, MD, medical director for the Texas Department of Family and Protective Services (DFPS). (texmed.org)

Results: Using the proposed BHPR approach, we estimated the BMI profiles of participants with T2DM diverged from healthy participants at age 16 years for males (95% credible interval (CI):13.5-18 years) and 21 years for females (95% CI: 19.5-23 years). (monash.edu)

The current "psychosocial environment" approach with its attention to of job control and other social risk factors has probably had its most effective use in explaining patterns of cardiovascular disease (CVD). (cdc.gov)
These macroscopic models describe the temporal and spatial evolution of traffic density without predicting traffic patterns of individuals. (enn.com)
Preclinical studies linked to AD have shown that poor circadian activity patterns increase the risks of dementia and precede cognitive malfunction. (news-medical.net)

The use of omic data derived from identical and non-identical same sex twins allows a greater understanding of the role of genetic and environmental factors in chronic pain conditions. (upf.edu)
Facial phenotype is a key diagnostic indicator for hundreds of genetic syndromes and computer-assisted facial phenotyping is a promising approach to assist diagnosis. (bvsalud.org)
genetic information to perform EHR data imputation.We used the individual single nucleotide polymorphism's association with phenotype variables in the EHR as input to construct a genetic risk score that quantifies the genetic contribution to the phenotype. (nih.gov)
Multiple approaches to constructing the genetic risk score were evaluated for optimal performance. (nih.gov)
The genetic score, along with phenotype correlation, is then used as a predictor to impute the missing values.To demonstrate the method performance, we applied our model to impute missing cardiovascular related measurements including low-density lipoprotein, heart failure, and aortic aneurysm disease in the electronic Medical Records and Genomics data. (nih.gov)
Associations of Diabetes Genetic Risk Counseling with Incident Diabetes and Weight: 5-Year Follow-up of a Randomized Controlled Trial. (cuanschutz.edu)

In the total sample, participants with good CRF had more favourable scores across nearly all risk markers than counterparts with poor CRF. (frontiersin.org)

mathematical modelling and evaluation studies. (bath.ac.uk)

LAB NAME: Cardiovascular Nutrition In the next 5 years the Cardiovascular Nutrition Laboratory (CNL) will investigate the effects of diets differing in fat type and carbohydrate type on cardiometabolic risk factors, fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions using human, animal and in vitro models. (usda.gov)
These discoveries are the results of lengthy and high risk studies, which would have not been accomplished without the R35 grant mechanism and the hard work and devotion of students, residents , fellows and visiting scholars in my laboratory, many of whom have gone to establish their own labs, or join the industry. (yale.edu)
A 10-year non-laboratory-based risk prediction chart was developed for fatal and non-fatal CVD using Cox Proportional Hazard regression. (irancohorts.ir)
Data from the Isfahan Cohort Study (ICS), a population-based study among 6504 adults aged ≥ 35 years, followed-up for at least ten years was used for the non-laboratory-based model derivation. (irancohorts.ir)
The WHO oversight committee has now declared that satisfactory (if in some areas imperfect) progress has been made toward developing improved vaccines, better laboratory diagnostics, a reasonable nonhuman primate animal model, effective antiviral drugs, and good understanding of the genetics of orthopoxviruses. (cdc.gov)

The last CVD risk calculator, the Pooled Cohort Equation, was released in 2013. (northwestern.edu)
We discuss implications of this model, including the potential utility of SSRIs as antihypertensives in this cohort. (psychiatrictimes.com)

Regulating apoC-III metabolism may be an important new therapeutic approach to managing dyslipidaemia and CVD risk in the metabolic syndrome. (portlandpress.com)
We leverage modern techniques of functional genomics, epigenetics, transcriptomics, proteomics, gene editing and model-driven experimentation to understand the underlying causes of atherosclerosis and metabolic syndrome and discover therapeutic targets. (yale.edu)
In recent years, modulation of the circadian clock, particularly the daily feed/fast cycle, has been explored as a therapeutic approach. (news-medical.net)

As a result, automated, objective approaches for measuring cardiac MPI SPECT are in great demand. (news-medical.net)

Among new markers, growth differentiation factor 15 and the mid-regional part of the prohormone of adrenomedullin, have shown some promising results. (degruyter.com)

An animal model that fully recapitulates severe COVID-19 presentation in humans has been a top priority since the discovery of SARS-CoV-2 in 2019. (cdc.gov)

suggesting higher, but not diabetic levels of blood glucose confer a risk, thus, effective preventive strategies may prove successful in prediabetes. (lu.se)

Micro-Ultrasound, possibly with a urine biomarker test, to accurately determine a patient's risk for prostate cancer and aid in decisions about whether to undergo prostate biopsy. (pcf.org)
Cite this: Model Helps Optimize Who Should Be Screened for Cancer - Medscape - Nov 08, 2023. (medscape.com)
To accomplish this, methods that evaluate cardiovascular risk prior to treatment and integrate evidence-based cancer treatment regimens with cardiovascular screening, diagnostic, and/or management strategies are sought. (nih.gov)

Dyslipidaemia in the metabolic syndrome is potently atherogenic and, hence, is a major risk factor for CVD (cardiovascular disease) in these subjects. (portlandpress.com)
In particular, CRD have been repeatedly shown to promote weight loss and improve fasting and postprandial triglycerides, and plasma HDL-cholesterol (HDL-C), which indicates that such an approach may be an important treatment option for the dyslipidemia associated with the metabolic syndrome [ 2 ]. (biomedcentral.com)

1.3 - Synergistic effects of a 'heart healthy' diet and statin therapy on atherosclerosis using a porcine model. (usda.gov)
People with diabetes have a greater risk of developing atherosclerosis and therefore have greater risk of peripheral arterial disease. (escardio.org)

DISCUSSION: Our results demonstrate that MRI scans encode relevant site-specific information that models could use as shortcuts that cannot be removed using simple intensity harmonization methods. (bvsalud.org)

An integrated risk factor approach is one that combines the effect of conventional risk predictors and non-invasive carotid ultrasound image-based phenotypes. (minervamedica.it)

In addition to well-established risk factors (e.g., hypertension, dyslipidemia, and smoking), some other factors such as choice of lifestyle, food habits, occupation, and physical inactivity complicate body homeostasis that greatly enhances the risk of ASCVD and other cardiometabolic disorders that may lead to life-threatening situations [ 2 ]. (hindawi.com)
The objectives of our intervention were to reduce cardiovascular disease risk factors in Hispanics living in 2 low-income areas of El Paso, Texas, and to engage the community in a physical activity and nutrition intervention. (cdc.gov)

The final model shows that social support (JCQ) was directly related to all 4 factors of the WHOQOL-BREF and inversely related to depression and stress (DASS). (biomedcentral.com)
Finally, stress, anxiety and depression (DASS) mediate the relationships between job demand and social support (JCQ) to the 4 factors of WHOQOL-BREF. (biomedcentral.com)
Serotonergic medications are routinely used to treat depressive and anxiety disorders, and the association of depression with cardiovascular disease has become well established.2 Recent studies have confirmed the colloquial wisdom that anxiety (especially panic) and hypertension are linked. (psychiatrictimes.com)
Serotonergic medications are routinely used to treat depressive and anxiety disorders, and the association of depression with cardiovascular disease has become well established. (psychiatrictimes.com)

Additionally, logistic regression models were used to investigate the contribution of biological (age, sex, disease status) and non-biological (scanner type) variables to the models' decision. (bvsalud.org)

OBJECTIVE: This work investigates if deep learning (DL) models can classify originating site locations directly from magnetic resonance imaging (MRI) scans with and without correction for intensity differences. (bvsalud.org)

Chronic kidney disease (CKD) and cardiovascular disease (CVD) together result in an enormous burden on global healthcare. (minervamedica.it)

A decline in age-specific incidence of dementia, at least in high-income countries, is theoretically possible, driven by changes in exposure to suspected developmental, lifestyle and cardiovascular risk factors for dementia [ 6 ]. (biomedcentral.com)

Background and AimsLow birth weight is a common pregnancy complication, which has been associated with higher risk of cardiometabolic disease in later life. (imperial.ac.uk)
Individuals with sensitivity to blood lipids, and blood pressure associated predictors were at higher risk to develop cardiometabolic disease. (lu.se)

Anatomy5

Diseases62

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment68

Psychiatry and Psychology15

Phenomena and Processes35

Anthropology, Education, Sociology and Social Phenomena8

Information Science10

Named Groups10

Health Care84

Geographicals34

Diseases21

Obesity10

Associated with cardiovascular disease2

Complications7

Mortality11

Modifiable4

Targeted cardiovascular disease1

Diabetes mellitus6

Assessment14

Clinical17

Outcomes8

Rates of cardiovascular disease1

Prevention13

Coronary artery2

Interventions to reduce1

Biomarkers7

Type 2 diabet6

Stroke11

Epidemiology1

Patients22

NCDs3

Analyses3

Atherosclerotic5

Prevalence3

Prediction models3

Health18

Bayesian2

Reduce CVD risk1

Behavioral2

Longitudinal4

CVDs3

Pathophysiology1

Adverse1

Ailments1

T2DM1

Patterns3

Genetic6

Favourable1

Mathematical1

Laboratory5

Cohort2

Therapeutic3

Cardiac1

Markers1

20191

Blood glucose1

Cancer3

Metabolic syndrome2

Atherosclerosis2

Methods1

Phenotypes1

Physical2

Depression4

Investigate1

Objective1

Chronic kidney1

Dementia1

Cardiometabolic disease2