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  • oral
  • Following a single 600 mg oral dose of rifampin in healthy adults, the peak serum concentration averages 7 mcg/mL but may vary from 4 to 32 mcg/mL. (nih.gov)
  • In healthy adults, the mean biological half-life of rifampin in serum averages 3.35 ± 0.66 hours after a 600 mg oral dose, with increases up to 5.08 ± 2.45 hours reported after a 900 mg dose. (nih.gov)
  • Following a single 900 mg oral dose of rifampin in patients with varying degrees of renal insufficiency, the mean half-life increased from 3.6 hours in healthy adults to 5.0, 7.3, and 11.0 hours in patients with glomerular filtration rates of 30 to 50 mL/min, less than 30 mL/min, and in anuric patients, respectively. (nih.gov)
  • HGE was suspected, and she was given oral rifampin (10 mg/kg orally twice daily). (aappublications.org)
  • leprae
  • These findings will be of use for the development of a rapid screening procedure, involving the polymerase chain reaction, for monitoring the emergence of rifampin-resistant M. leprae strains. (epfl.ch)
  • daily
  • Rifampin is usually taken daily. (wellspan.org)
  • Rifabutin 300mg (Group 1) or rifampin 600mg (Group 2) will be administered once daily during Period 2 from Study Day 20 through Study Day 41. (clinicaltrials.gov)
  • In addition, some side effects have been reported when rifampin was taken intermittently (not daily), or restarted after a period of not using the drug. (emedtv.com)
  • relapse
  • For rifampin, the corresponding MIC values were 0.0695 ± 0.0276 µg/mL and 0.0453 ± 0.0223 µg/mL, representing a 1.53-fold higher value in the relapse group. (medicalxpress.com)
  • Higher pretreatment MIC values for either isoniazid or rifampin were associated with an increased risk of relapse, even after accounting for other potential risk factors for relapse ," write the authors of an accompanying editorial. (medicalxpress.com)
  • breast milk
  • Rifampin can pass into breast milk and may harm a nursing baby. (wellspan.org)
  • Because rifampin is excreted in human breast milk and animal studies have shown that the drug has the potential to cause tumors to form, you shouldn't take it if you are breastfeeding. (everydayhealth.com)
  • liver
  • Before taking rifampin, tell your doctor if you have ever had liver problems or liver disease, any condition that affects your adrenal glands, porphyria (disorders that mainly cause nerve or skin problems), or diabetes. (everydayhealth.com)
  • medication
  • Rifampin may also be used for purposes not listed in this medication guide. (wellspan.org)
  • RifAMPin may reduce the blood levels of HYDROcodone, which may make the medication less effective in treating your pain. (drugs.com)
  • Click Rifampin for more detailed information on this medication, including how it works and why it may not be suitable for some people. (emedtv.com)
  • pregnancy
  • However, taking rifampin during the last few weeks of pregnancy may cause bleeding in the mother or the newborn baby. (wellspan.org)
  • Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking rifampin. (wellspan.org)
  • Rifampin is an FDA Pregnancy Category C Drug, meaning research in animals indicates it can be harmful to a developing baby, but human studies are lacking. (everydayhealth.com)