• It is caused by Ehrlichia ruminantium (formerly Cowdria ruminantium) - an intracellular Gram-negative coccal bacterium (also referred to as Rickettsia ruminantium). (wikipedia.org)
  • This tick species is a known vector for Rickettsial organisms, Rickettsia parkeri, and Ehrlichia ruminantium, formerly Cowdria ruminantium. (health.mil)
  • There are reports of zoonotic infections of humans by E. ruminantium, similar to other Ehrlichia species, such as those that cause human ehrlichiosis. (wikipedia.org)
  • In areas endemic for heartwater, the use of dips against other ticks of domestic animals, such as Rhipicephalus (Boophilus) and Hyalomma species is likely, and this will usually contribute to control of vectors of E. ruminantium. (wikipedia.org)
  • Service members may be at increased risk of contracting SFR because of residence in regions with endemic rickettsial species and frequent field training in tick habitats. (health.mil)
  • One of the most important new developments related to ehrlichiosis is the realization that a given mammalian species can be infected simultaneously or sequentially by several Ehrlichia species. (vin.com)
  • Of comparative medical interest, cats, dogs, humans, as well as other domestic and wild animal species, can all be infected with the same Anaplasma or Ehrlichia sp. (vin.com)
  • Although the clinicopathologic course of disease will vary depending upon the infecting Ehrlichia species, illness is typically characterized by an acute reduction in cellular blood elements, most often thrombocytopenia. (vin.com)
  • Co-infection with multiple Ehrlichia species or Ehrlichia and Anaplasma spp. (vin.com)
  • Sequencing of 16S rDNA, sodB, and groEL genes indicated that the bacterium is most likely a novel Ehrlichia species. (cdc.gov)
  • Recognized species include E. canis, E. chaffeensis, E. ewingii, E. muris, and E. ruminantium ( 1 ). (cdc.gov)
  • Two recently identified new species are Ehrlichia sp. (cdc.gov)
  • To delineate the molecular mechanism of midgut response to E. ruminantium infection, we performed comparative analyses of midgut transcriptomes of E. ruminantium infected engorged A. hebraeum nymphs, and infected adult male and female ticks with their corresponding matched uninfected controls, before and during feeding. (bvsalud.org)
  • Annotation of DEGs revealed an increase in metabolic and cellular processes among E. ruminantium infected ticks. (bvsalud.org)
  • Heartwater is a rickettsial disease of domestic and wild cattle, deer, sheep, and goats that is spread by infected ticks. (iastate.edu)
  • The clinical picture and the history of tick exposure suggested a rickettsial infection. (cdc.gov)
  • A. phagocytophilum and A. platys ), B. burgdorferi sensu stricto, and Ehrlichia spp. (cdc.gov)
  • Canine ehrlichiosis is an infectious rickettsial disease of dogs, caused by E. canis, E. chaffeensis, and E. ewingii and potentially E. ruminantium . (vin.com)
  • Heartwater (also known as cowdriosis, nintas, and ehrlichiosis) is a tick-borne rickettsial disease. (wikipedia.org)
  • the tick was removed en bloc with surrounding conjunctiva by an ophthalmologist. (liverpool.ac.uk)
  • We also observed up-regulation of glycoproteins that E. ruminantium could potentially use as docking sites for host cell entry. (bvsalud.org)
  • To definitively diagnose the disease, C. ruminantium must be demonstrated either in preparations of the hippocampus under Giemsa staining or by histopathology of brain or kidney. (wikipedia.org)
  • Conversely, observations in human patients have contributed to the recognition of an increased spectrum of disease manifestations in animals, such as acute renal failure or acute respiratory distress syndrome (ARDS) in dogs infected with Ehrlichia sp. (vin.com)
  • Often, the experimental characterization of the immunopathological response of a specific Ehrlichia sp. (vin.com)
  • 6 , 7 ) in horse serum, no reports have documented isolation or PCR detection of Ehrlichia spp. (cdc.gov)
  • It is caused by Ehrlichia ruminantium (formerly Cowdria ruminantium) - an intracellular Gram-negative coccal bacterium (also referred to as Rickettsia ruminantium). (wikipedia.org)
  • Continuous cell lines from the ticks Amblyomma variegatum, Boophilus decoloratus, Boophilus microplus, Hyalomma anatolicum anatolicum, Ixodes scapularis, Ixodes ricinus and Rhipicephalus appendiculatus were tested for ability to support growth of the rickettsial pathogen Ehrlichia (previously Cowdria) ruminantium. (nih.gov)
  • This tick species is a known vector for Rickettsial organisms, Rickettsia parkeri , and Ehrlichia ruminantium , formerly Cowdria ruminantium . (cdc.gov)
  • Heartwater (also known as cowdriosis) is an acute, fatal, non-contagious, infectious, tick-borne rickettsial disease of ruminants caused by Ehrlichia ruminantium (formerly Cowdria ruminantium) and transmitted by Amblyomma ticks. (gov.ie)
  • Heartwater (also known as cowdriosis, nintas, and ehrlichiosis) is a tick-borne rickettsial disease. (wikipedia.org)
  • In areas endemic for heartwater, the use of dips against other ticks of domestic animals, such as Rhipicephalus (Boophilus) and Hyalomma species is likely, and this will usually contribute to control of vectors of E. ruminantium. (wikipedia.org)
  • R. parkeri is a member of the spotted fever group of rickettsial diseases affecting humans, while E. ruminantium causes heartwater disease, an infectious, noncontagious, tick-borne disease of domestic and wild ruminants, including cattle, sheep, goats, antelope, and buffalo. (cdc.gov)
  • Heartwater, or cowdriosis, is a virulent tick-borne rickettsial disease of ruminants caused by Ehrlichia ruminantium, biologically transmitted by Amblyomma species (A. variegatum in West Africa). (bvsalud.org)
  • Additionally, studies will investigate whether sheep that are seropositive due to infestation by E. ruminantium-infected R. microplus are subsequently protected against heartwater. (bvsalud.org)
  • Ticks can transmit Ehrlichia ruminantium , the cause of heartwater, and consequently the importation of African reptiles has been controlled. (merckvetmanual.com)
  • These families have major genera Anaplasma, Ehrlichia and Neorickettsia ( Anaplasmataceae ) and Rickettsia ( Rickettsiaceae ) that contain multiple pathogens of importance to veterinary medicine ( Table 21.1 ). (veteriankey.com)
  • While Ehrlichia, Anaplasma and Rickettsia species are primarily tick transmitted, Neorickettsia species are transmitted by ingestion of infected trematodes. (veteriankey.com)
  • Our results confirm that R. microplus can acquire and transmit E. ruminantium to the next stage. (bvsalud.org)
  • Although there has been a longstanding need for veterinary and human vaccines for diseases caused by rickettsial pathogens, this is an area that needs further attention to prevent and treat these life‐threatening infections in animals and humans. (veteriankey.com)
  • This chapter summarizes the current knowledge of major rickettsial pathogens ( Table 21.1 ) and associated diseases in livestock and companion animals, emphasizing disease pathogenesis, immunity, and immunopathology. (veteriankey.com)
  • Expansion of tick vectors and natural animal hosts of many rickettsial pathogens has been well documented and is a major contributing factor to the increasing emergence of rickettsial zoonoses in humans. (veteriankey.com)
  • Table 21.1 Important rickettsial pathogens of domestic and wild animals. (veteriankey.com)
  • E.ruminantium was transferred from these infected cell lines to B.decoloratus, B.microplus and R. appendiculatus cell lines. (nih.gov)
  • Bacterial infection in these sheep was demonstrated by detecting antibodies to E. ruminantium using the MAP1-B ELISA and by isolation of the bacterium on cell culture from blood. (bvsalud.org)
  • Mites may also be associated with mechanical transmission of Aeromonas hydrophila , a variety of other bacteria, rickettsial agents, and viruses. (merckvetmanual.com)