• Elucidation of the O-specific polysaccharide chain of lipopolysaccharide (LPS) from Rickettsia typhi, the etiological agent of endemic typhus, is described. (gu.se)
  • Rickettsial homeostasis is continuously regulated as rickettsiae cycle between the warm-blooded vertebrate and poikilothermic invertebrate hosts. (beds.ac.uk)
  • A temperature shift may thus also signal a change in rickettsial gene expression to overcome the drop in temperature experienced within the flea, thereby promoting survival of the rickettsiae. (beds.ac.uk)
  • 3)-alpha-D-GlcNAc may represent a common epitope in the O-antigens of Proteus vulgaris OX19 and R. typhi responsible for the observed serological cross-reactivity. (gu.se)
  • when the host scratches the site, the lice are crushed, and the Rickettsia- laden excrement is inoculated into the bite wound. (medscape.com)
  • After a patient with typhus is treated with antibiotics and the disease appears to be cured, Rickettsia may linger in the body tissues. (medscape.com)
  • We hypothesize that temperature plays a role in regulating host-specific gene expression, allowing R. typhi to survive in mammalian and arthropod hosts. (beds.ac.uk)
  • The ability of rickettsiae to survive in multiple eukaryotic host environments provides a good model for studying pathogen-host molecular interactions. (beds.ac.uk)
  • The goal of this study was to perform a genome-wide screen for differentially transcribed R. typhi genes in response to a shift in temperature from 37°C to 25°C. This experimental design mimicks the temperature transition the rickettsiae may experience as they are acquired by the flea host from a rickettsemic mammal. (beds.ac.uk)
  • Visit our research pages for current research about Rickettsia typhi treatments . (rightdiagnosis.com)
  • Current research efforts have focused on molecular interactions between pathogenic rickettsiae and their mammalian hosts. (beds.ac.uk)
  • In December, which was the wet season, 23.3%, 3.0%, and 57.3% of the population had antibodies detected against the three rickettsiae, respectively. (ajtmh.org)
  • Subjects less than 21 years old had a lower seroprevalence of SFG rickettsiae compared with the other age groups. (ajtmh.org)