• Molecular analysis of skin samples indicated the agent was a novel spotted fever group strain closely related to Rickettsia africae, R. parkeri, and R. sibirica. (labome.org)
  • In vitro activities of telithromycin compared to those of erythromycin against Rickettsia spp. (eurekamag.com)
  • Evaluation of the Inhibitory Activity of Small Molecule Compounds Against Rickettsia prowazekii Methionine Aminopeptidase (MetAp) using in vitro & in vivo Assays. (ssgcid.org)
  • For this project we propose to screen the NIU library of approximately 500 MetAP-focused compounds against R. prowazekii (RiprA.00039.a) using both in vitro and in vivo assays. (ssgcid.org)
  • Interactions between Rickettsia prowazekii and cultured host cells: alterations induced by gamma interferon. (thefreedictionary.com)
  • There the rickettsiae grow, filling the host cell cytoplasm causing cell lysis and systemic dissemination. (ssgcid.org)
  • SSGCID has solved the structure of Methionine aminopeptidase from Rickettsia prowazekii (RiprA.00039.a) in both an apo state and methionine-bound state (PDB ID: 3MR1 & 3MX6). (ssgcid.org)
  • Rickettsia prowazekii has been tested for biological warfare due to the high mortality that it produces after aerosol transmission of very low numbers of rickettsiae. (utmb.edu)