Ribosomal s6 kinase mrna ribosomal. Medical search. Frequent questions

The mammalian target of rapamycin (mTOR) is an evolutionarily highly conserved intracellular serine/threonine kinase family member. (hindawi.com)
Akt (protein kinase B) is a cellular serine/threonine protein kinase that has been implicated in cellular growth and survival. (surgicalneurologyint.com)
Mammalian target of rapamycin (mTOR), a serine/threonine kinase involved in diverse cellular processes, including protein translation, mRNA turnover, and protein stability, mediates, at least in part, some of the biological actions of Akt. (surgicalneurologyint.com)
Background The serine-threonine protein kinase mammalian target of rapamycin (mTOR), which is definitely inhibited from the immunosuppressant drug rapamycin regulates several intracellular pathways in response to numerous extracellular signals, nutrient availability, energy status of the cell and stress. (researchensemble.com)
mTORC1 is certainly a proteins complicated made up of the serine/threonine kinase mTOR the scaffolding proteins raptor and mLST8 [3]. (healthyconnectionsinc.com)
A family of protein serine/threonine kinases which act as intracellular signalling intermediates. (bvsalud.org)
It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. (genetex.com)
The p70S6K is a serine/threonine kinase that phosphorylates eIF4B at Ser422 directly. (researchhunt.com)
Mitogen- and stress-activated proteins kinase 1 (MSK1), known as RPS6KA5 also, is certainly a serine/threonine kinase that belongs to RSK (Ribosomal Protein-S6 Kinase) family members and is certainly ubiquitously expressed in a variety of tissues and mostly expressed in the mind, center, placenta, and skeletal muscle groups (7). (campaignfornonviolentschools.org)
is a kinase enzyme , in particular a protein kinase , that phosphorylates the OH group of the amino-acid residues serine or threonine , which have similar side chains. (cloudfront.net)
At least 350 of the 500+ human protein kinases are serine/threonine kinases (STK). (cloudfront.net)
In enzymology , the term serine/threonine protein kinase describes a class of enzymes in the family of transferases , that transfer phosphates to the oxygen atom of a serine or threonine side chain in proteins . (cloudfront.net)
Serine/threonine kinases play a role in the regulation of cell proliferation, programmed cell death ( apoptosis ), cell differentiation, and embryonic development. (cloudfront.net)
While serine/threonine kinases all phosphorylate serine or threonine residues in their substrates, they select specific residues to phosphorylate on the basis of residues that flank the phosphoacceptor site, which together comprise the consensus sequence . (cloudfront.net)
Types include those acting directly as membrane-bound receptors ( Receptor protein serine/threonine kinase ) and intracellular kinases participating in Signal transduction . (cloudfront.net)

The mGluR5-ERK1/2 pathway is not constitutively overactive in the Fmr1 KO, however, suggesting that mRNA translation is hypersensitive to basal ERK1/2 activation in the absence of FMRP. (jneurosci.org)
For instance, it can be activated by oncogenic mutations of PTEN, VHL, the RAS/mitogen-activated protein kinase (MAPK) pathway and the phosphorylation of phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway. (spandidos-publications.com)
2004) S6K1(−/−)/S6K2(−/−) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. (concordia.ca)
PKA in turn activates the mTOR pathway, which promotes the translation of mRNA into protein by activating key regulators of protein synthesis such as ribosomal protein S6 kinase (S6K) and eukaryotic initiation factor 4E-binding protein (4E-BP1). (cariatidegioielli.com)
Phosphatidylinositol-3-kinase (PI3-K) pathway has been reported as an important intracellular mediator frequently activated in cancer cells [ 2 ]. (biomedcentral.com)
The phosphatidyl inositol 3-kinase (PI3K)/Akt pathway was involved in this ubiquitin-proteasome-mediated degradation of PDCD4. (plos.org)

Markedly, we found that suppression of HIF-1α accumulation by celastrol correlated with strong dephosphorylation of mammalian target of rapamycin (mTOR) and its effectors, ribosomal protein S6 kinase (p70S6K) and eukaryotic initiation factor 4E (eIF4E) and extracellular signal-regulated kinase (ERK), pathways known to regulate HIF-1α expression at the translational level. (spandidos-publications.com)
These pathways involve mTOR-dependent activation of the 70 kDa ribosomal protein S6 kinase (p70S6K) as well as the inactivation of the repressor of mRNA translation, eukaryotic initiation element 4E (eIF4E) binding protein (4EBP) [1,2]. (researchensemble.com)
The protein levels of phospho-phosphatidylinositol 3-kinase, protein kinase B, phospho-eukaryotic initiation factor 4E binding protein-1 (p-4E-BP1), 4E-BP1 and ribosomal protein S6 kinase 1, in the liver of fish fed the 0.84% diet were higher than those in fish fed the 0.40% diet. (researchsquare.com)
Protein kinases constitute one of the largest and most important of protein families, accounting for ~2% of genes in a variety of eukaryotic genomes. (wormbook.org)
Most protein kinases share a common ePK (eukaryotic protein kinase) catalytic domain, and can be identified by sequence similarity with Blast or profile hidden Markov models (HMMs). (wormbook.org)
Finally two inhibitors of 4E-binding proteins phosphorylation the phosphoinositol 3-kinase inhibitor LY294002 along with a phosphorylation site mutant of 4E-binding proteins-1 that dominantly inhibits eukaryotic initiation element-4E each clogged TGF-β- induced α-actin manifestation and cell enhancement. (cancerrealitycheck.com)
Initial translation of nearly all eukaryotic mRNAs is set up via a 7-methylguanosine cover structure in the 5′ end of mRNA. (cancerrealitycheck.com)

Phosphorylation of ribosomal protein S6 (RPS6) on ser235/236 and ser240/244 in the pancreatic beta cell increases cell size and insulin content and influences systemic glucose homeostasis. (diabetesjournals.org)
Phosphorylation of RIBOSOMAL PROTEIN S6 by enzymes in this class results in increased expression of 5' top MRNAs. (bvsalud.org)

Our data suggest that elevated protein synthesis in the Fmr1 KO is due to saturation of mRNA translation downstream of the MAP kinase ERK1/2 which is basally activated by mGluR5. (jneurosci.org)
Insulin signaling affects multiple downstream pathways including mitogen-activated protein kinase (MAPK), which controls growth, sterol regulatory element-binding protein 1 (SREBP-1), which stimulates the synthesis of lipid and cholesterol as well as the family of Forkhead (FOXO) transcription factors regulating metabolism and autophagy [ 9 ] [ 10 ] . (encyclopedia.pub)
Immunostains of human airway sections revealed concordant activation of Akt (reflected in Ser(473) phosphorylation) and of its downstream effector p70(S6Kinase) (reflected in Thr(389) phosphorylation) within airway muscle bundles, but there was no phosphorylation of the alternative Akt downstream target glycogen synthase kinase (GSK) 3β. (nih.gov)
Human homologs of the AKT8 oncogenic protein were identified in 1987.By 1995 it had been found that Akt kinases function as mitogen-activated kinases downstream from cell surface receptors that activate phosphoinositide 3-kinase . (cloudfront.net)

p27(Kip1) is a cyclin-dependent kinase inhibitor. (biomedcentral.com)

Fragile X syndrome (FXS) is caused by loss of the FMR1 gene product FMRP (fragile X mental retardation protein), a repressor of mRNA translation. (jneurosci.org)

Inhibition of AKT activity by wortmannin or over-expression of dominating negative AKT clogged arsenic-induced MLN0128 cyclin D1 manifestation and transformation [5 6 Short-term exposure to numerous concentrations of arsenite (5-50 μM) raises phosphorylation of p70-KDa ribosomal protein S6 kinase (p70S6K) in human being prostate DU145 cells [7]. (researchhunt.com)

Further analysis revealed that celastrol inhibited HIF-1α protein synthesis, without affecting the expression level of HIF-1α mRNA or degradation of HIF-1α protein. (spandidos-publications.com)
Summary We conclude that mTOR has a part in maintaining prolonged pain claims via mRNA translation and thus protein synthesis. (researchensemble.com)

mTORC1 also phosphorylates the S6Ks that subsequently phosphorylate multiple translation elements including ribosomal and eIF4B proteins S6. (healthyconnectionsinc.com)

More recently, Co-workers and Cost have got implicated particular spine mRNA translation pathways in formalin-induced behavioural hypersensitivity [9]. (researchensemble.com)
Protein kinases are one of the largest and most influential of gene families: constituting some 2% of the proteome, they regulate almost all biochemical pathways and may phosphorylate up to 30% of the proteome. (wormbook.org)
By phosphorylating substrate proteins, kinases modify the activity, location and affinities of up to 30% of all cellular proteins, and direct most cellular processes, particularly in signal transduction and co-ordination of complex pathways. (wormbook.org)
Many of these pathways are highly conserved, and 53 distinct kinase functions and subfamilies appear to have been conserved between yeasts, nematodes, insects and vertebrates, with a further 91 subfamilies of kinases being seen throughout metazoan genomes. (wormbook.org)
MSK1 is certainly turned on by extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 mitogen-activated proteins kinase pathways in response to development factor and mobile tension stimuli (7). (campaignfornonviolentschools.org)

4E-BPs certainly are a grouped category of little protein that affiliate with eIF4E an mRNA cap-binding proteins. (healthyconnectionsinc.com)
eIF4E as well as eIF4G and eIF4A type the eIF4F complicated that recruits the tiny (40S) ribosomal subunit towards the 5′-end of mRNA. (healthyconnectionsinc.com)
Phosphorylation by mTOR of 4E-BP1 disrupts its binding to eIF4E, a protein that binds the 5'-cap structure of mRNA. (biomedcentral.com)
4E-BP1 goes through phosphorylation at multiple sites which outcomes in its launch from Bafetinib (INNO-406) eIF4E therefore increasing the option of eIF4E for binding to eIF4G eIF4F complicated development and cap-dependent translation (21 22 Second concurrent using the planning of mRNA the preinitiation complicated must be shaped. (cancerrealitycheck.com)

Background Mammalian focus on of rapamycin organic 1 (mTORC1) is a proteins kinase that relays nutrient availability indicators to control many cellular features including autophagy an activity of cellular self-eating activated by nutrient depletion. (healthyconnectionsinc.com)
PPm1K knockdown did not increase phosphorylation of p70 S6 Kinase (S6K) or the mammalian target of rapamycin (mTOR) upstream of RPS6 suggesting that PPm1K regulates RPS6 phosphorylation in an mTOR-S6K independent manner. (diabetesjournals.org)

Treating SMMC-7721 cells with 5-Fu leads to apoptosis of the cells, and reduction in telomerase activity, as well as a dramatic reduction in the activated form of p70 S6 kinase, a mTOR substrate. (biomedcentral.com)
Since the consensus sequence residues of a target substrate only make contact with several key amino acids within the catalytic cleft of the kinase (usually through hydrophobic forces and ionic bonds ), a kinase is usually not specific to a single substrate, but instead can phosphorylate a whole 'substrate family' which share common recognition sequences. (cloudfront.net)
Many kinases are inhibited by a pseudosubstrate that binds to the kinase like a real substrate but lacks the amino acid to be phosphorylated. (cloudfront.net)

While the catalytic domain of these kinases is highly conserved , the sequence variation that is observed in the kinome (the subset of genes in the genome that encode kinases) provides for recognition of distinct substrates. (cloudfront.net)

Compared with 0.40% dietary methionine, 1.28% methionine enhanced the mRNA levels of the hepatic gluconeogenesis related genes phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase, and the muscular glycolysis related genes phosphofructokinase (PFK) and pyruvate kinase (PK). (researchsquare.com)
Such radiations include genes involved in spermatogenesis, chemosensation, Wnt signaling and FGF receptor-like kinases. (wormbook.org)
We identified 438 protein kinase genes, including 20 atypical kinases, and an additional 25 kinase fragments or pseudogenes. (wormbook.org)
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. (genetex.com)
DNA microarrays make it possible to analyze the mRNA expression of thousands of genes simultaneously. (karger.com)

Free circulating insulin activates insulin receptors on the surface of target cells eliciting a signaling cascade initiated by the activation of insulin receptor substrates (IRS 1-4) followed by phosphorylation of phosphoinositide 3-kinase (PI3K), which manages metabolic response including PDK1 and Akt stimulation by phosphorylation. (encyclopedia.pub)
b) 4-Hydroxytamoxifen (but not tamoxifen), genistein (but not genistin), daidzein, and probably other nutritional and chemopreventive anti-cancer agents could up-regulate expression of p27 via receptor protein tyrosine kinases (RPTKs), phosphoinositide 3-kinase (PI3K), phosphoinosite-dependent kinase (PDK), Akt/PKB and mTOR. (biomedcentral.com)

Finally the translation of mRNAs with 5′ Best tracts a lot of which encode elongation elements and ribosomal protein involved with mRNA translation can be upregulated by successive phosphorylation of mTOR S6K-1 as well as the S6 ribosomal proteins. (cancerrealitycheck.com)

Mitogen- and stress-activated proteins kinase 1 (MSK1) was markedly induced after PI3K/mTOR inhibitor treatment and disruption of MSK1 by particular shRNAs attenuated level of resistance to PI3K/mTOR inhibitors in glioma initiating cells (GICs). (campaignfornonviolentschools.org)

Their studies centered on mice missing delicate mental retardation gene (FMR1), which is another proteins that affects translation mRNA. (researchensemble.com)
This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. (genetex.com)
Specifically, the PDCD4 protein combines directly with the mRNA coding region of the target gene ( MYB/c-MYB ) to block translation [2] . (plos.org)
The gene codes for a protein kinase. (cloudfront.net)
Alternatively TGF-β improved α-soft muscle tissue synthesis in the current presence of actinomycin D an inhibitor of gene transcription demonstrating that TGF-β escalates the translation of α-actin mRNA into proteins. (cancerrealitycheck.com)

eIF2 a multimer comprising α β and γ subunits features to recruit methionyl tRNA and carry out it like a tRNA-eIF2-GTP ternary complicated towards the 40S ribosomal subunit to create the 43S preinitiation complicated. (cancerrealitycheck.com)

PI3K/mTORC1 сигнальний шлях залучений до контролю багатьох клітинних функцій, що регулюють фосфорилування одного зі своїх медіаторів - кінази 1 рибосомного протеїну S6 (S6K1). (ukrbiochemjournal.org)

Спочатку in vitro кіназний тест підтвердив здатність p60-S6K1 фосфорилувати рибосомний протеїн S6 (rpS6), відомий субстрат S6K1. (ukrbiochemjournal.org)

A further 91 subfamilies were found in all three metazoan kinomes, including the tyrosine kinase (TK) group and the TKL group, which mediate much of the complexity of intercellular signal transduction. (wormbook.org)

Although specific for RIBOSOMAL PROTEIN S6 members of this class of kinases can act on a number of substrates within the cell. (bvsalud.org)

The classification is based on sequence similarity within the kinase domain, the presence of additional domains, known biological functions, and conservation across divergent genomes. (wormbook.org)

1998) Regulation of the p70 S6 kinase by phosphorylation in vivo. (concordia.ca)

The increase in tuberin phosphorylation and the decrease tuberin expression are associated with decrease in OGG1 protein and mRNA levels in tumor samples compared to normal kidney samples. (biomedcentral.com)
This study was designed to test a novel immunotherapy strategy using a vaccine enriched for short-lived proteins (SLiPs) and defective ribosomal products (DRiPs) derived from autologous tumor cells. (biomedcentral.com)

In addition, muscular PEPCK and glycogen synthase, and hepatic glucose transporters 2 mRNA levels were induced by 1.28% methionine. (researchsquare.com)

The cyclin-dependent kinase (CDK) inhibitor p27(Kip1) is a key cell-cycle regulator of G1-to-S phase transition [ 1 ]. (biomedcentral.com)
Further inhibition of 4E-BP phosphorylation by way of a chemical substance inhibitor Bafetinib (INNO-406) of PI 3-kinase LY294002 attenuated TGF-β-induced airway soft muscle cell enhancement and α-soft muscle actin manifestation. (cancerrealitycheck.com)

FISH, single-molecule fluorescence in situ hybridization (smFISH) analysis, which revealed that C. Thus, although these species use different mechanisms to become more P body-like, the shift in germ granules initially protect their constituent mRNAs from degradation, they subsequently target a subset of germ plasm after water or CHX injection. (commercialsuicide.org)
We discovered that TGF-β got no influence on α-actin mRNA balance and pilot pulse-chase research show no degradation of radiolabeled α-actin proteins 48 h after drawback of popular probe (not really shown) recommending that proteins degradation will not are likely involved. (cancerrealitycheck.com)

Confocal immunofluorescent analysis of HeLa cells, insulin-treated (left) and LY294002-treated (#9901, right), using Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP ® Rabbit mAb (Alexa Fluor 488 ® Conjugate) (green). (cellsignal.com)

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks. (ukrbiochemjournal.org)
Functions and regulation of the 70kDa ribosomal S6 kinases. (ukrbiochemjournal.org)

AKT regulates an array of oncogenic procedures including cell development proliferation and apoptosis through phosphorylation of various other proteins kinases transcription elements and signaling modulators. (researchhunt.com)

The remaining atypical protein kinases (aPK) belong to several families, some of which have structural, but not sequence similarity to ePKs. (wormbook.org)

Homo sapiens IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) (IBA57), mRNA. (dbcls.jp)

The phospho-4E-BP1 (Thr46) antibody was bought from Invitrogen (Carlsbad CA). Kinase inhibitors Rapamycin and LY294002 had been bought from EMD Chemical substances (NORTH PARK CA). The and control little interfering RNAs (siRNAs) had been bought from Santa Cruz Biotechnology (Santa Cruz CA). Sodium arsenite was bought from Sigma (St. Louis MO). (researchhunt.com)

11. Antion MD, Hou L, Wong H, Hoeffer CA, Klann E (2008) mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice. (concordia.ca)

Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes. (jci.org)
Glucose has been reported to increase the de novo synthesis of diacylglycerol (DAG) and translocate and activate protein kinase C (PKC) in rat adipocytes. (jci.org)

The 5-Fu treatment nearly abolishes transcription of hTERT (the major component of telomerase) mRNA. (biomedcentral.com)

Hanyu-Nakamura K, Nakamura A, Besse F. RNP components condense into repressive RNP granules in regulating mRNA stability xalatan price per pill Knockdown of decapping proteins are limiting, we overexpressed DCP1. (commercialsuicide.org)

Homo sapiens BUB3 mitotic checkpoint protein (BUB3), transcript variant 2, mRNA. (dbcls.jp)
Homo sapiens CGG triplet repeat binding protein 1 (CGGBP1), transcript variant 1, mRNA. (dbcls.jp)
Homo sapiens shugoshin-like 1 (S. pombe) (SGOL1), transcript variant A1, mRNA. (dbcls.jp)

We find that beta cells account for most PPm1K expression within pancreatic islets and that exposure of INS1 832/13 beta cells to increasing concentrations of glucose results in suppression of PPm1K mRNA expression. (diabetesjournals.org)

When clenbuterol binds to the beta-2 adrenergic receptor, it causes an increase in cAMP levels, leading to the activation of protein kinase A (PKA). (cariatidegioielli.com)

The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. (genetex.com)

Distribution of 212 kinase subfamilies throughout four kinomes: the yeast Saccharomyces cerevisiae , the nematode worm Caenorhabditis elegans , the fruit fly Drosophila melanogaster and human. (wormbook.org)

while hepatic SREBP1, FAS and ACC mRNA expression levels were increased by 0.40% methionine. (researchsquare.com)
The mRNA expression levels of hepatic PFK, PK and glucokinase were markedly upregulated by the 0.84% methionine diet compared with the 1.28% diet. (researchsquare.com)
Finally, (d) global hypomethylation of 5'-m 7 G cap of mRNAs could also up-regulate expression of p27. (biomedcentral.com)
These data indicate that tuberin deficiency in angiomyolipoma enhances mTOR activation by phosphorylation of S6K and downregulation of protein and mRNA expression of OGG1 resulted in accumulation of oxidized DNA in patients with TSC. (biomedcentral.com)
Temporary blockade of NKG2D signaling during the effector phase resulted in the formation of highly defective memory CD8 T cells characterized by altered expression of the ribosomal protein S6 and epigenetic modifiers, suggesting modifications in the T cell translational machinery and epigenetic programming. (bmj.com)
Temporary blockade of NKG2D signaling during the effector phase results in the formation of highly defective memory CD8 T cells potentially by affecting the expression of the ribosomal protein S6 and epigenetic modifiers, suggesting alterations in T cell translational machinery and epigenetic programming. (bmj.com)

Kinases are deeply conserved in evolution, and the worm has family homologs for over 80% of the human kinome. (wormbook.org)
To put worm kinases into an evolutionary and functional context, we compared them with the distant kinomes of human, fly, and yeast. (wormbook.org)
Nematodes share 153 subfamilies with human, providing close homologs for 81% (419/518) of all human kinases. (wormbook.org)
Application of unidirectional pulsatile shear stress to human umbilical vein endothelial cells (HUVECs) decreased PDCD4 protein but not mRNA level. (plos.org)
First we confirmed that TGF-β raises steady-state α-actin mRNA amounts in human being airway soft muscle tissue cells (Shape 4A). (cancerrealitycheck.com)

The immunosuppressant SIROLIMUS inhibits the activation of ribosomal protein S6 kinases. (bvsalud.org)

Since kinases perform such a variety of distinct basic cellular functions, it is not surprising to see that 53 subfamilies and functions are present in all four kinomes ( Figure 1 ). (wormbook.org)

Homo sapiens intercellular adhesion molecule 1 (ICAM1), mRNA. (dbcls.jp)
Ribosomal protein S6 kinases are activated through phosphorylation in response to a variety of HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. (bvsalud.org)

All sequences and supporting data are available at http://kinase.com , and all but 8 sequences are now identical to wormpep (v. 141) sequences. (wormbook.org)

Forced protein kinase B/Akt 1 activation is known to induce myocyte hypertrophy in other muscle types, and, since a number of mediators present in asthmatic airways can activate Akt signaling, we hypothesized that Akt activation could contribute to ASM hypertrophy in asthma. (nih.gov)

The protein belongs to the S6E family of ribosomal proteins. (genetex.com)

Phosphorylation of Atg13 by TOR precludes the binding of Atg13 to Atg1 producing a marked reduction in the kinase activity of Atg1 [11]. (healthyconnectionsinc.com)

Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (ERCC3), mRNA. (dbcls.jp)
The purpose of this study is to determine the effect of tuberin-deficiency on OGG1 protein and mRNA levels as well as on 8-oxodG levels in kidney tumors from patients with TSC. (biomedcentral.com)

Anatomy17

Organisms8

Diseases1

Chemicals and Drugs167

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes42

Disciplines and Occupations1

Information Science3

Serine15

Pathway6

Eukaryotic7

Phosphorylation of ribosomal pr2

Downstream4

Cyclin-dependent kinase1

Repressor of mRNA translation1

P70S6K1

Protein synthesis2

Phosphorylates1

Pathways5

EIF4E4

Mammalian2

Substrate3

Highly conserved1

Genes5

Phosphoinositide2

Encode1

Proteins kinase1

Gene5

Subunit1

PI3K1

RpS61

Signal Transduction1

Substrates1

Genomes1

19981

Tumor2

Glycogen synthase1

Inhibitor2

Degradation2

Ser2401

Regulation2

Apoptosis1

Atypical1

Homolog1

LY2940021

Elongation1

Synthesis2

Transcription1

Knockdown1

Transcript3

Glucose1

Receptor1

Translation1

Saccharomyces1

Expression6

Human5

Inhibits1

Cellular1

Intercellular2

Sequences1

Activation1

Belongs1

Reduction1

Deficiency2