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  • rRNA gene
  • 1994 Effectes of rRNA gene copy number and nucleolar variation on early development: inhibition of gastrula- tion in rDNA-deficient chick embryos. (springer.com)
  • 1974. Variation in nucleolar organizer rRNA gene multiplicity in wheat and rye. (springer.com)
  • In this study, we defined a novel function of nuclear ErbB2 in enhancing rRNA gene transcription by RNA polymerase-I (RNA Pol I). Nuclear ErbB2 physically associates with β-actin and RNA Pol I, coinciding with active RNA Pol I transcription sites in nucleoli. (aacrjournals.org)
  • Using a species-specific polymerase chain reaction (PCR) targeting the small subunit (SSU) ribosomal RNA (rRNA) gene, we detected P. ovale in nearly 4% of the inhabitants of a northeastern Cambodian village. (ajtmh.org)
  • The 16S rDNA for two strains of toxic M. aeruginosa were sequenced and compared to available cyanobacterial, bacterial, and chloroplast 16S rRNA gene information. (semanticscholar.org)
  • Using next generation sequencing of DNA and 5S ribosomal RNA we show here that specific DNA signatures distinguish the 5S rRNA gene copies from the three major 5S rDNA loci . (gred-clermont.fr)
  • With these tools, we revealed sequence polymorphisms between the different 5S rRNA gene copies and between loci as well as differential enrichment in epigenetic marks linked to differential gene expression. (gred-clermont.fr)
  • Finally, our results indicate important plasticity among ecotypes in 5S rRNA gene expression both between 5S rDNA loci and within a particular locus . (gred-clermont.fr)
  • Although genes with many conserved regions such as the 16S rRNA gene often fail to remain in our assemblies, some of our bins did contain these genes occasionally. (merenlab.org)
  • Primers used to amplify specific regions of the LSU rRNA gene from oyster ( Crassostrea virginica ) genomic DNA and cDNA template. (utexas.edu)
  • Comparative secondary structure model of the LSU rRNA gene of Crassostrea hongkongensis . (utexas.edu)
  • Comparative secondary structure model of the LSU rRNA gene of the Placozoan species (BZ10101). (utexas.edu)
  • DNA methylation in coding regions of rRNA genes was positively correlated with copy number of 45S rRNA gene and DNA methylation in the intergenic spacer regions. (beds.ac.uk)
  • There is considerable genetic variation in the mt 16S rRNA gene of I. scapularis . (biomedcentral.com)
  • gene provided 69 variable sites, and the sequenced 410-bp segment of 12S rRNA gene provided 21 variable sites. (nii.ac.jp)
  • gene within ingroup were 0.0022~0.0205 at the populational level, 0.0368~0.0462 at the racial or subspecific level, and 0.1038~0.1244 at the specific level, whereas those of the 12S rRNA gene were 0~0.0074 at the populational or subspecific level, and 0.0378~0.0456 at the specific level. (nii.ac.jp)
  • The phylogenetic trees constructed from the nucleotide sequences of the 12S rRNA gene also showed distinct divergence between two species, but not any divergence within species. (nii.ac.jp)
  • Based on 16S rRNA gene analysis, Moritella marina shows nearly identical similarities with other Moritella species (97-99% identity with other species) (Fig. 1). (kenyon.edu)
  • elegans
  • Previously, we have shown that the ncl-1 gene in Caenorhabditis elegans functions as an inhibitor of cell growth and ribosome synthesis. (biologists.org)
  • We now indicate that the Drosophila melanogaster tumor suppressor brain tumor ( brat ) is an inhibitor of cell growth and is a functional homolog of the C. elegans gene ncl-1 . (biologists.org)
  • The only other gene that has so far been shown to negatively regulate RNA polymerase I and III transcription is ncl-1 (for abnormal nucleolus) from the soil nematode Caenorhabditis elegans . (biologists.org)
  • Protein
  • RNA interference-mediated knockdown of ErbB2 reduced pre-rRNA and protein synthesis. (aacrjournals.org)
  • rRNA production by RNA polymerase-I (RNA Pol I), the key component of ribosome biogenesis, is the rate-limiting step for translation/protein synthesis and cell growth. (aacrjournals.org)
  • In fact, recent studies have shown that one mechanism of cell growth regulation is achieved through an insulin receptor signaling pathway, one of the most downstream targets of which is the ribosomal protein S6 ( Weinkove and Leevers, 2000 ). (biologists.org)
  • Additionally, they have a higher rate of 5S RNA synthesis and probably contain more ribosomes as they contain more protein than do wild-type worms ( Frank and Roth, 1998 ). (biologists.org)
  • 20047967 ). Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes (By similarity). (uniprot.org)
  • In this study we report the dual functionality of tlyA gene product of Mycobacterium tuberculosis annotated as Rv1694, a 268 amino acid long basic protein. (biomedcentral.com)
  • epigenetic
  • Given their repetitive nature and their localization in the pericentromeric regions of the genome, 5S rRNA genes are only partly assembled in the reference genome, which has rendered detailed analyses of their organization, dynamics and epigenetic regulation difficult. (gred-clermont.fr)
  • copies
  • There are 34 predicted RNAs, one predicted copy of 16S rRNA, and four predicted copies of 23S rRNA (Kautharapu and Jarboe 2012). (kenyon.edu)
  • genetic
  • The genetic markers that contribute to detecting and monitoring the susceptibility of P. falciparum to doxycycline, the pfmdt and pftetQ genes, have recently been identified. (biomedcentral.com)
  • transcription
  • Finally, ErbB2-potentiated RNA Pol I transcription could be stimulated by ligand and was not substantially repressed by inhibition of PI3-K and MEK/ERK (extracellular signal regulated kinase), the main ErbB2 effector signaling pathways. (aacrjournals.org)
  • nucleolus
  • The brat gene is able to rescue the large nucleolus phenotype of ncl-1 mutants. (biologists.org)
  • The ribosomal genes coding for the 45S rRNA precursor of the three largest eukaryotic ribosomal RNAs (18S, 5.8S, and 25-28S) are found in nucleolus organizer regions (NORs), comprised of hundreds to thousands of repeats, only some of which are expressed in any given cell. (beds.ac.uk)
  • large
  • Due to their essential role and the requirement to be produced in large quantities, 5S rRNA genes are highly repeated in the genome. (gred-clermont.fr)
  • control
  • In order to understand its mechanism of pathogenesis in humans and to help control tuberculosis, functions of numerous Mycobacterium tuberculosis genes are being characterized. (biomedcentral.com)
  • physical
  • A physical map of the 5S and 18S-26S rRNA genes was determined using bi-color fluorescence in situ hybridization technique in A. victorialis var. (springer.com)
  • important
  • The presence and high concentration of rRNA genes in air suggests that atmospheric transport, which can lead to secondary infection, may be more important than currently estimated. (frontiersin.org)