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  • phosphatase
  • Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti- inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. (discoverx.com)
  • vivo
  • This product is an active protein and may elicit a biological response in vivo, handle with caution. (abcam.com)
  • nuclear
  • IκBα inhibits NF-κB by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an inactive state in the cytoplasm. (wikipedia.org)