• In enzymology, a 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) is an enzyme that catalyzes the chemical reaction 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole ⇌ {\displaystyle \rightleftharpoons } 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate Hence, this enzyme has one substrate, 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole, and one product, 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. (wikipedia.org)
  • This thiyl radical then initiates the nucleotide reduction process by hydrogen atom abstraction from the ribonucleotide [ PMID: 9309223 ]. (ebi.ac.uk)
  • This entry represents a subfamily of 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthases represented by the Thermotoga maritima (Tm) enzyme [ PMID: 16582479 ] and E. coli PurC [ PMID: 1534690 ]. (ebi.ac.uk)
  • It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate [ PMID: 15641804 ]. (ebi.ac.uk)
  • When you look at the reactions that people get from gluten vs. MSG and ribonucleotide (itchy rash, migraine headache, insomnia, irritability, anxiety, puffiness, bloating, etc.), you will see that they are nearly identical reactions. (healthybliss.net)
  • Welcome to our special feature on the effects of new additive ribonucleotides (flavour enhancer 635, a mixture of 631disodium guanylate and 627disodium inosinate), which cause what we call Ribo Rash. (fedup.com.au)
  • For example, the enzymes glutaredoxin 1, thioredoxin 1, and thioredoxin 2 are each capable of reducing the essential enzyme ribonucleotide reductase to regenerate its activity in vivo and in vitro ( 5 , 6 ). (pnas.org)
  • For the four different ribonucleotides in this prebiotic scenario, there would be hundreds of other possible isomers. (allaboutscience.org)
  • If there was not in fact a prebiotic pool of beta-D-ribonucleotides (as is required by the RNA world model), then the entire hypothesis of an RNA world formed by natural processes is invalid. (allaboutscience.org)
  • In this report, we show that Tetrahymena telomerase was able to incorporate a ribonucleotide, rGTP, into product polynucleotide. (nih.gov)
  • In 1957, Akira Kuninaka realized that the ribonucleotide GMP present in shiitake mushrooms also conferred the umami taste. (wikipedia.org)
  • Scientists have found that the flavour enhancing effect of MSG is increased up to 10 to 15 times when MSG is used in combination with ribonucleotides. (fedup.com.au)