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  • Pathways
  • Annotation described in this paper also reveals evidence for several metabolic pathways that have yet to be observed experimentally, including a sulphur oxidation ( sox FCDYZAXB) gene cluster, Calvin cycle enzymes, and proteins involved in nitrogen fixation in other species (including RubisCo, ribulose-phosphate 3-epimerase, and nif gene families, respectively). (biomedcentral.com)
  • A total of 11,195 protein-coding genes were predicted including a diverse group of gene families involved in hydrocarbon degradation pathways like dioxygenases and cytochrome P450. (biomedcentral.com)
  • strain
  • The Sphingomonas macrogolitabida strain TFA is a gram-negative bacterium that is able to grow on tetralin (1,2,3,4-tetrahydronaphthalene) as the only carbon and energy source ( 14 ). (pubmedcentralcanada.ca)
  • Strains
  • Fully sequenced in October 2006, the genome is known to be 9.7 megabasepairs long and 67% G/C. Strains of Rhodococcus are important owing to their ability to catabolize a wide range of compounds and produce bioactive steroids, acrylamide, and acrylic acid, and their involvement in fossil fuel biodesulfurization. (wikipedia.org)
  • sequence
  • Biodegradability tests and partial sequence analysis of the enrichment culture indicated that 4-aminopyridine was mainly degraded via 3,4-dihydroxypyridine and that the metabolite is probably cleaved by 3-hydroxy-4-pyridone dioxygenase. (biomedcentral.com)
  • metabolites
  • Octylphenol polyethoxylates (OPEOn) are surfactants and prone to be degraded into xenoestrogenic metabolites, such as octylphenol and OPEOn (n=1-2), are estrogenic-like compounds, and persistent to be degraded by bacteria in the environments. (ncu.edu.tw)
  • Pathway
  • It follows the above pathway through 2-hydroxybenzimidazole. (ethz.ch)
  • The pathway followed is the same as for the above two organisms, through 2-hydroxybenzimidazole. (ethz.ch)
  • carbon and energy
  • SG-4G is capable of using carbendazim, 2-aminobenzimidazole, and 2-hydroxybenzimidazole as sole carbon and energy sources for growth. (ethz.ch)
  • complex
  • An example of this is the use of Rhodococcus to produce indene, a precursor to the AIDS drug indinavir, a protease inhibitor, and containing two of the five chiral centers needed in the complex. (wikipedia.org)
  • nitrogen
  • Rhodococcus jialingiae djl-6-2 is capable of using carbendazim as the sole carbon and nitrogen source for growth. (ethz.ch)
  • A 4-aminopyridine-degrading enrichment culture utilized 4-aminopyridine as a carbon, nitrogen, and energy source, generating 4-amino-3-hydroxypyridine, 3,4-dihydroxypyridine, and formate as intermediates. (biomedcentral.com)
  • Bacterial
  • Changes in the bacterial populations of 4-aminopyridine, 3,4-dihydroxypyridine, or formate/ammonium chloride enrichment cultures were monitored by denaturing gradient gel electrophoresis (DGGE) profiling of PCR-amplified 16S rRNA gene fragments. (biomedcentral.com)
  • step
  • With respect to the initial step of biphenyl degradation, expression of all sets of ring hydroxylating dioxygenase genes (bphA, etbAl, etbA2) likewise is induced by biphenyl, and gene disruption experiments suggested that all these genes are involved in biphenyl degradation (Takeda et al. (alpfmedical.info)
  • 2006). Two cis-dihydrodiol dehydrogenases BphB1 and BphB2, which are encoded on pRHL1 and pRHL2, respectively, catalyze the second step in biphenyl catabolism, i.e., the rearomatization of the cis-dihydrodiol to form 2,3-dihydroxybiphenyl. (alpfmedical.info)
  • conversion
  • Benomyl, methyl N-[1-(butylcarbamoyl)benzimidazol-2-yl]carbamate, and its conversion product, carbendazim, methyl benzimidazol-2-yl carbamate, are systemic fungicides. (ethz.ch)
  • respectively
  • 4AP-Z were predominant in 4-aminopyridine and formate/ammonium chloride enrichment cultures and in the 3,4-dihydroxypyridine enrichment culture, respectively. (biomedcentral.com)
  • product
  • 4-Amino-3-hydroxypyridine could not be further metabolized and probably accumulated as a dead-end product in the culture. (biomedcentral.com)
  • ability
  • This, along with its ability to reduce perchlorate (a teratogenic contaminant introduced into the environment by man) and inquiry into its use in biocells [ 3 ] has led to interest in using this organism for bioremediation and energy production. (biomedcentral.com)
  • growth
  • Rhodococcus is also an experimentally advantageous system owing to a relatively fast growth rate and simple developmental cycle, but is not well characterized. (wikipedia.org)