• The effect of concomitant hyperthermia on the cytotoxicities of cis -diamminedichloroplatinum(II) (CDDP), a newly synthesized drug, Pt(Rh-123) 2 , and its chemical components, K 2 PtCl 4 and rhodamine 123, was examined in vitro in a squamous cell tumor line of human origin (SCC-25) and in a CDDP-resistant subline (SCC-25/CP). (aacrjournals.org)
  • Cytoplasmic exclusion of rhodamine 123 was used as an indicator of MDR1 function to measure the effect of hypotonic stress, MDR1 inhibitors, and Cl - channel blockers on MDR1 transport function. (elsevier.com)
  • In contrast to the 24-h IR, the injury did not have any effect on the hepatobiliary disposition of RH-123 or its metabolites following 72 h of reperfusion. (ualberta.ca)
  • P-gp inhibitory effect of aqueous extracts (250 µg/mL) from some medicinal plants and verapamile (5 µg/mL) was measured using flow cytometry by Rhodamine 123 (Rh123) in Caco2 cell line. (rjpharmacognosy.ir)