• Designated a notifiable disease by the Office International des Epizooties, SVC is caused by a rhabdovirus, spring viremia of carp virus (SVCV). (musiceye11.com)
  • Serological testing of these isolates by virus neutralisation indicated that they were antigenically closely related to pike fry rhabdovirus (PFRV) but not spring viraemia of carp virus (SVCV), while testing by enzyme-linked immunosorbent assay indicated them to be antigenically different from both. (int-res.com)
  • The genome encodes for the typical five proteins found in all rhabdoviruses: nucleocapsid (N), phosphoprotein (P), matrix (M), glycoprotein (G), and polymerase (L). However, there are three additional genes, U1-U3, that encode for proteins of unknown function. (wikimili.com)
  • The genome of SVCV is composed of a single molecule of linear, negative-sense, single-stranded RNA containing 5 genes in the order 3'-NPMGL-5' coding for the viral nucleoprotein, phosphoprotein, matrix protein, glycoprotein, and polymerase, respectively. (musiceye11.com)
  • Like other rhabdoviruses, IHNV is characterized by an envelope consisting of trimers of a glycoprotein that display multiple N-linked oligosaccharides and play an integral role in viral infection by mediating the virus attachment and fusion. (nsf.gov)
  • Comparison of nucleotide sequence data of a 550 base pair segment of the viral glycoprotein generated by reverse transcription-polymerase chain reaction indicated a high (≥96.6%) degree of similarity between these isolates and a previous Northern Ireland isolate made in 1984, a 1997 isolate from bream in the Republic of Ireland and an earlier Dutch isolat from roach. (int-res.com)
  • Viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus belonging to the Novirhabdovirus genus, causes severe disease and mortality in many marine and freshwater fish species worldwide. (biomedcentral.com)
  • Virus particles also contain a matrix protein that coils the nucleocapsid and a surface glycoprotein that spans the viral envelope to associate with the matrix protein and the nucleocapsid core. (berkeley.edu)
  • To address some of these gaps in knowledge, we used Zebrafish as a model system to examine the role of galectins in infection by infectious hematopoietic necrosis virus (IHNV), a rhabdovirus that is responsible for significant losses in both farmed and wild salmonid fish. (nsf.gov)
  • These results show that A. aegypti was subjected to repeated Rhabdovirus infectious episodes during its evolution history, which led to the accumulation of many integrated sequences. (unicamp.br)
  • We established the reverse genetics systems for both IHNV and VHSV whereby infectious rhabdovirus can be recovered entirely from cDNA clones. (usmd.edu)
  • Using an existing clone of the trout-avirulent VHSV-IVb strain MI03 (pVHSVmi), eight chimeric VHSV clones were constructed in which the coding region(s) of the glycoprotein (G), non-virion protein (NV), G and NV, or G, NV and L (polymerase) genes together, were exchanged between the two clones. (biomedcentral.com)
  • The sprivivirus genome contains five genes in the order 3′- N - P - M - G - L- 5′ encoding a nucleoprotein, polymerase-associated protein, matrix protein, glycoprotein and RNA-directed RNA polymerase, respectively (Figure 1. (ictv.global)
  • Antibodies directed against SVCV react with the homologous virus in serum neutralization, immunofluorescence, immunoperoxidase, or enzyme-linked immunosorbent assays, but they cross-react to various degrees with the pike fry rhabdovirus (PFR), suggesting the 2 viruses are closely related. (musiceye11.com)
  • Viruses assigned to the genus Sprivivirus belong to one of the five rhabdovirus genera that infect finfish, the other genera being Perhabdovirus , Siniperhavirus , Scophrhavirus and Novirhabdovirus . (ictv.global)
  • Experiments using a recombinant vesicular stomatitis virus expressing the EKV-1 envelope glycoprotein indicate EKV-1 has very broad tropism and can efficiently enter nearly all types of human cells. (wikimili.com)
  • Experiments using a recombinant vesicular stomatitis virus expressing the EKV-2 envelope glycoprotein indicate EKV-2 has very broad tropism similar to EKV-1. (wikimili.com)
  • A recombinant vaccinia virus expressing herpes simplex virus type 1 (HSV-1) glycoprotein G (gG) has been constructed. (microbiologyresearch.org)
  • and a minus strand plant rhabdovirus, sonchus yellow net virus. (berkeley.edu)
  • These include a negative strand plant rhabdovirus, sonchus yellow net virus (SYNV) that replicates in the nucleus, and a tripartite plus sense RNA virus, barley stripe mosaic virus (BSMV) that replicates in the cytoplasm. (berkeley.edu)
  • Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. (unibe.ch)
  • Covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes. (jefferson.edu)
  • Functional human immunodeficiency virus type 1 (HIV-1) Gag-Pol or HIV-1 Gag-Pol and env expressed from a single rhabdovirus-based vaccine vector genome. (jefferson.edu)
  • ABSTRACT: Rhabdovirus was isolated from wild common bream Abramis brama during a disease outbreak with high mortality in Northern Ireland during May 1998. (int-res.com)
  • A single immunization with a rhabdovirus-based vector expressing severe acute respiratory syndrome coronavirus (SARS-CoV) S protein results in the production of high levels of SARS-CoV-neutralizing antibodies. (jefferson.edu)
  • The rabies genome encodes five proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G) and polymerase (L). All rhabdoviruses have two major structural components: a helical ribonucleoprotein core (RNP) and a surrounding envelope. (cdc.gov)
  • Importantly, SnRK1-glycoprotein and ATG6-glycoprotein interactions were well-conserved between several other rhabdoviruses and plants. (bvsalud.org)
  • Paramyxovirus glycoprotein incorporation, assembly and budding: a three way dance for infectious particle production. (microbiologyresearch.org)
  • The M-RNP complex binds with the glycoprotein, and the completed virus buds from the plasma membrane. (cdc.gov)
  • Although G protein synthesis is initiated on free ribosomes, completion of synthesis and glycosylation (processing of the glycoprotein), occurs in the endoplamsic reticulum (ER) and Golgi apparatus. (cdc.gov)
  • Rabies virions are bullet-shaped with 10-nm spike-like glycoprotein peplomers covering the surface. (cdc.gov)
  • Although RV pathogenicity is a multigenic trait involving several elements of the RV genome, the RV glycoprotein plays a major role in RV pathogenesis by controlling the rate of virus uptake and trans-synaptic virus spread, and by regulating the rate of virus replication. (medscape.com)
  • The causative agent is rabies virus (RV), a negative-stranded RNA virus of the rhabdovirus family, which has a relatively simple, modular genome organization and encodes five structural proteins: a RNA-dependent RNA polymerase (L), a nucleoprotein (N), a phosphorylated protein (P), a matrix protein (M) and an external surface glycoprotein (G). The N, P and L proteins form, together with the genomic RNA, the ribonucleoprotein complex (RNP). (medscape.com)
  • Functional human immunodeficiency virus type 1 (HIV-1) Gag-Pol or HIV-1 Gag-Pol and env expressed from a single rhabdovirus-based vaccine vector genome. (jefferson.edu)
  • The physical interactome between Peregrinus maidis proteins and the maize mosaic virus glycoprotein provides insights into the cellular biology of a rhabdovirus in the insect vector. (ncsu.edu)
  • 13. A viable recombinant rhabdovirus lacking its glycoprotein gene and expressing influenza virus hemagglutinin and neuraminidase is a potent influenza vaccine. (nih.gov)
  • Subtypes of Influenza A are distinguished by the two surface glycoproteins: haemagglutinin (HA) and neuraminidase (NA). (biomedcentral.com)
  • The RSV fusion (F) glycoprotein is a dominant antigen and a prominent vaccine target, and has been determined in the pre- and postfusion states. (revaccsci.com)
  • A single immunization with a rhabdovirus-based vector expressing severe acute respiratory syndrome coronavirus (SARS-CoV) S protein results in the production of high levels of SARS-CoV-neutralizing antibodies. (jefferson.edu)
  • Cytoplasmic tails of bunyavirus Gn glycoproteins-Could they act as matrix protein surrogates? (expasy.org)
  • The M protein is associated both with the envelope and the RNP and may be the central protein of rhabdovirus assembly. (cdc.gov)
  • However, little is known about the role of autophagy in the defense against rhabdovirus infection by plant. (bvsalud.org)