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  • viscosity
  • Overall, these studies with high concentration, low viscosity subcutaneous injections of protein therapeutics open new opportunities in biotechnology. (utexas.edu)
  • As high solution viscosity prevents the use of subcutaneous injection as a delivery method for some mAbs, a fundamental understanding of the interactions responsible for high viscosities in concentrated mAb solutions is of significant relevance to mAb applications in human health care as well as of intellectual interest. (aps.org)
  • formulation
  • Due to solubility/dosing limits with the subcutaneous formulation, 1,600 μg/kg/week was the maximal administered dose. (aacrjournals.org)
  • Based on the favorable safety profile and the evidence of clinical benefit noted in this study, additional clinical studies with aflibercept, using either i.v. administration or an improved subcutaneous formulation, both as a single agent and in combination with other anticancer drugs, are in progress. (aacrjournals.org)
  • doses
  • In this open-label, dose-escalation study, patients with advanced solid tumors were treated with subcutaneous doses of aflibercept at seven dose levels. (aacrjournals.org)
  • In humans, subcutaneous administration of single daily doses of leuprolide acetate results in an initial increase in circulating levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH), leading to a transient increase in levels of the gonadal steroids (testosterone and dihydrotestosterone in males, and estrone and estradiol in pre-menopausal females). (nih.gov)
  • syringe
  • Healthcare professionals should train patients in the proper technique for self-administering subcutaneous injections using the prefilled pen or syringe. (drugs.com)
  • Each single-dose, prefilled syringe of ARIXTRA, affixed with an automatic needle protection system, contains 2.5 mg of fondaparinux sodium in 0.5 mL, 5.0 mg of fondaparinux sodium in 0.4 mL, 7.5 mg of fondaparinux sodium in 0.6 mL, or 10.0 mg of fondaparinux sodium in 0.8 mL of an isotonic solution of sodium chloride and water for injection. (rxlist.com)
  • The mixture is given by a slow injection into a vein (called an infusion) over an hour using a syringe-pump or with a drip. (drugs.com)
  • hormone
  • What will be the effects of daily hormone injections on his self-esteem? (aappublications.org)
  • Aveed ( testosterone undecanoate) Injection is a form of the male hormone, testosterone, used for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone. (rxlist.com)
  • edema
  • Despite the existence of these treatments, chronic venous edema, which is a derivation of stasis papillomatosis, is only partially reversible. (wikipedia.org)
  • Chronic venous edema is only partially reversible and soon becomes hard, especially confirming tenderness. (wikipedia.org)
  • contraceptive
  • Depending on the type, an injectable lasts for one, two or three months before a new injection is needed to maintain efficacy as a contraceptive. (psi.org)
  • The three-month, progestin-only injectable contraceptive is packaged in the Uniject™ injection system - a small, easy to use, all-in-one, pre-filled device. (psi.org)
  • administration
  • This is an extract from the Summary of Product Characteristics (SmPC) to assist in the administration of Securon IV for intravenous injection. (drugs.com)
  • Subcutaneous injection of naloxonazine (20 mg/kg) 24h prior to the administration of DAMGO (5 mg/kg) also blocked the reduction in the response latency observed when DAMGO was injected alone. (ac.ke)
  • implants
  • Penile implant surgery is reserved now for those men with failed or unacceptable reversible methods (ICI, oral therapy or vacuum device), although some men with difficulties attaching external drainage devices may find penile implants helpful. (scireproject.com)
  • sodium chloride
  • It is available in a 2.8 mL multiple-dose vial containing leuprolide acetate (5 mg/mL), sodium chloride, USP (6.3 mg/mL) for tonicity adjustment, benzyl alcohol, NF as a preservative (9 mg/mL), and water for injection, USP. (rxlist.com)
  • Each 0.2 mL contains 1 mg of leuprolide acetate, sodium chloride for tonicity adjustment, 1.8 mg of benzyl alcohol as preservative and water for injection. (rxlist.com)
  • Patients
  • Patients should be advised to rotate sites for subcutaneous injections. (drugs.com)
  • The leading drug in Genta's small molecule program is Ganite(R) (gallium nitrate injection), which the Company is exclusively marketing in the U.S. for treatment of symptomatic patients with cancer related hypercalcemia that is resistant to hydration. (bio-medicine.org)
  • In patients undergoing hip fracture, hip replacement, or knee replacement surgery, the recommended dose of ARIXTRA is 2.5 mg administered by subcutaneous injection once daily after hemostasis has been established. (rxlist.com)
  • In some situations, patients may be able to give themselves these injections at home. (chemocare.com)
  • solution
  • Reversible cluster formation has been identified as an underlying cause of large solution viscosities observed in some concentrated monoclonal antibody (mAb) formulations. (aps.org)
  • Your doctor or nurse will prepare your injection by diluting it with water or salt solution, either in the vial or in another container. (drugs.com)
  • disorder
  • Transitory, reversible ophthalmologic refraction disorder and worsening of diabetic retinopathy has been reported with insulin initiation and glucose control intensification. (drugs.com)
  • drug
  • Our Aveed (testosterone undecanoate) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • Be aware that drug is for I.V. or subcutaneous use only. (thefreedictionary.com)
  • patient
  • In the 84-week clinical trial of Aveed, 1 patient experienced a mild coughing fit lasting 10 minutes after his third injection, which was retrospectively attributed to POME. (rxlist.com)
  • versus
  • Mean weight gain from baseline was similar for women receiving medroxyprogesterone by the subcutaneous or intramuscular routes (3.4kg versus 3.5kg at the end of year 2 and 4.5kg versus 5.8kg at the end of year 3). (mims.co.uk)