Reveals conserved sequence. Medical search. Frequent questions

Conserved non-coding sequences can be important sites of evolutionary divergence as mutations in these regions may alter the regulation of conserved genes, producing species-specific patterns of gene expression. (wikipedia.org)
Introns are stretches of sequence found mostly in eukaryotic organisms which interrupt the coding regions of genes, with basepair lengths varying across three orders of magnitude. (wikipedia.org)
Regulatory motifs in UTRs often conserved in genes belonging to the same metabolic family could potentially be used to develop highly specific medicines that target RNA transcripts. (wikipedia.org)
The absence of genomic resources renders the search for paralogous cuttlefish genes dependent upon the presence of highly conserved protein motifs within genes of interest, thus we used a degenerate primer strategy to isolate partial coding sequence from the conserved domains specific to these families. (europa.eu)
Spatial expression analysis of both genes revealed that Sof-RXR is expressed ubiquitously in all cells of the embryo, including the chondrocytes, whereas Sof-ALDH was expressed only in a sub-set of epithelial cells and no expression at the level of chondrocytes was observed. (europa.eu)
For this, it identifies and clusters co-localized genes encoding proteins of secretion systems using sequence similarity search with Hidden Markov Model (HMM) protein profiles. (bvsalud.org)
DNA sequencing of 623 genes with known or potential relationships to cancer revealed more than 1,000 somatic mutations across the samples. (kb.se)
These data provide evidence of somatic mutations in primary lung adenocarcinoma for several tumour suppressor genes involved in other cancers--including NF1, APC, RB1 and ATM--and for sequence changes in PTPRD as well as the frequently deleted gene LRP1B. (kb.se)
Furthermore, comparative genomics through BES can be used for identifying positional candidate genes from QTL mapping studies, aid in future assembly of a reference genome sequence and elucidating sequence content and complexity in the rainbow trout genome. (biomedcentral.com)
RNAseq studies revealed targetable genes, but their inhibition did not result in improved vaccines. (unav.edu)
Widespread adoption of next-generation sequencing (NGS) technology has allowed for parallel sequencing of many genes. (medscape.com)
This document describes some of the target genes and primers that can be used for DNA sequence-based identification of fungi and the PCR conditions with which to use those primers. (cdc.gov)
Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes. (cdc.gov)
Furthermore, a genome-wide comparison of selection rates between large and small-bodied baleen whales revealed a small set of conserved candidate genes with potential connections to cancer resistance. (lu.se)
The recent success gut microbial genes, obtained after has fantastic potential, it has only of faecal microbiota transplantation, sequencing whole faecal microbiota been about 10 years since the sci- especially in the context of Clostridi- metagenomes from 124 European indi- entific community first realized its im- um difficile infection, argues for such viduals [4]. (who.int)
In 2014, the MetaHIT consortium by bacteria of the genera Lacto- alytical method used: 66 from 16S published an integrated catalogue bacillus , Prevotella , and Sneathia , rDNA sequencing [11] or 57 from of 10 million bacterial genes de- whereas for infants delivered by whole-metagenome sequencing [5]. (who.int)
In addition, long-read sequencing of one representative XDR ST235 isolate identified an integron carrying multiple resistance genes (including bla VIM-2), with differences in gene composition and synteny from the P. aeruginosa class 1 integrons described previously. (who.int)

Based on a predicted model of UMAMIT29, we propose that the substrate transporting cavity consists of 51 residues, of which four are highly conserved residues across all the analyzed homologs of UMAMIT29. (frontiersin.org)
By comparing differentially conserved residues within the predicted cavities between glucosinolate-transporting and non-glucosinolate-transporting UMAMITs, we identify 11 candidate residues. (frontiersin.org)
We hypothesised that the transport cavity contains highly conserved residues that are key for the transport activity. (frontiersin.org)
To test this, we aligned 97 protein sequences consisting of homologs of UMAMIT clade I from 27 plant species and created sequence logos containing the 51 residues identified in the structural analysis ( Supplementary Figure 1 ). (frontiersin.org)
Residues in the groove are highly conserved asmeasured from the information content of the aligned sequences. (embl.de)
It was revealed that the parts of the molecule which exhibit extensive motions at the μs-ms timescale correlates with the conserved residues in the sequence, expected to form an interaction surface with other subunits. (xray.cz)
The crystal structures of the conserved ETS domain of SAP-1 bound to DNA sequences from the E74 and c-fos promoters reveal that a set of conserved residues contact a GGA core DNA sequence. (rcsb.org)
Discrimination for sequences outside this core is mediated by DNA contacts from conserved and nonconserved protein residues and sequence-dependent DNA structural properties characteristic of A-form DNA structure. (rcsb.org)
The enzyme assumes a fold related to a (beta/alpha)8 barrel, with a long groove on the surface of the protein that harbours all conserved residues. (rcsb.org)

Comparison of amino acid sequences among MTGR1, MTG8, and Nervy revealed four evolutionarily conserved regions (NHR1 to NHR4). (embl-heidelberg.de)

Therefore, to address the growing volumes of available genomic sequence, a number of algorithms that identify putative cis-regulatory modules and transcription factor binding sites using evolutionary comparisons, whole-genome data, and known descriptions of transcription factor binding sites, have been successfully developed. (biomedcentral.com)

The tetraploid species in genus Nicotiana including section Polydiclae , Repandae , Nicotiana , Rustica and Sauveolentes revealed both up and downsizing in their genome sizes when compared to the sum of genomes of their ancestral species. (scielo.br)
Methods of this type assume that regulatory regions are highly conserved in cross-genomic comparison, and conserved segments can be extracted from evolutionary related genomes. (biomedcentral.com)
This is an actively progressing area, as more and more sequenced genomes appear. (biomedcentral.com)
Nowadays, the production of full Wolbachia genomes does not require the physical isolation of the bacterial strains from their respective hosts, and the bacterium is often sequenced as a by-catch of host genomic projects. (bvsalud.org)
To further investigate the genomic diversity among this group and to help characterize lineages of the plague organism that have no sequenced members, we present here the genomes of two isolates of the "classical" antiqua biovar, strains Antiqua and Nepal516. (asm.org)
We compare all five currently sequenced Y. pestis genomes and the corresponding features in Yersinia pseudotuberculosis . (asm.org)

Our structures, combined with the results from other biophysical and biochemical assays, reveal a common disease mechanism: the mutations in PLN reduce its phosphorylation level by changing its conformation and weakening its interactions with PKA. (elifesciences.org)
Background De novo mutations are emerging as an important cause of neurocognitive impairment, and whole exome sequencing of case-parent trios is a powerful way of detecting them. (bmj.com)
The analysis of these conserved sequences revealed that all epitopes identified by the Company are linear, accessible by antibodies, and unaffected by mutations. (bignewsnetwork.com)
Speaking on the role of Monoclonal Antibodies in targeting conserved sequences for Monkeypox, Dr. Suraj Saggar, an Advisory Board Member, said, 'Monkeypox is a DNA virus and is less prone to random mutations during replication versus an RNA virus-like SARS-Cov2. (bignewsnetwork.com)
Background Neoantigens, new immunogenic sequences arising from tumor mutations, have been associated with response to immunotherapy and are considered potential targets for vaccination. (unav.edu)
[ 5 , 6 ] have provided a clearer picture of the disease and reveal a spectrum of overlapping clinical features that can be correlated genotypically to the specific mutations in patients with pachyonychia congenita. (medscape.com)
As with most other keratin disorders, most mutations in pachyonychia congenita occur in these highly conserved helix boundary domains at the end of the rod domain. (medscape.com)
Genetic analysis of patients with leukocyte adhesion deficiency: genomic sequencing reveals otherwise undetectable mutations. (lu.se)

Bimodal exons are flanked by more conserved intronic sequences harboring distinct cis-regulatory motifs, constitute much of cell-type-specific splicing, are highly dynamic during cellular transitions, preserve reading frame, and reveal intricacy of cell states invisible to conventional gene expression analysis. (nih.gov)
A cadherin repeat is an independently folding sequence of approximately 110 amino acids that contains motifs with the conserved sequences DRE, DXNDNAPXF, and DXD. (embl.de)

Patterns of conserved introns between species of different kingdoms have been used to make inferences about intron density at different points in evolutionary history. (wikipedia.org)
Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. (kb.se)
In order to enrich the genomic tools already available in this species and provide further insight on the complexity of its genome, we sequenced a large number of rainbow trout BAC-end sequences (BES) and characterized their contents. (biomedcentral.com)
Comparative genomics using paired BAC-ends revealed several regions of conserved synteny across all the fish species analyzed in this study. (biomedcentral.com)
Nanos was first identified in Drosophila , where it represses the translation of target mRNAs through binding to their 3′ UTR and has a conserved function in germ cell development across species. (hindawi.com)
Multiple MTG8-related sequences are found in several vertebrate species, from fish to mammals, albeit not in a urodele. (embl-heidelberg.de)
Hebert P.D.N., Penton E.N., Burns J.M., Janzen D.H., Hallwachs W. (2004) Ten species in one: DNA barcoding reveals cryptic species in the neotropical skipper butterfly Astraptes fulgerator , Proc. (apidologie.org)
The sequence lengths vary greatly from approximately 200 basepairs to up to 700 basepairs depending on the species. (cdc.gov)
The Fusarium ID database contains EF1-α sequences for many species of Fusarium . (cdc.gov)

The potential application of our method includes annotation of new genomic sequences and motif discovery. (biomedcentral.com)
Despite the advent of next-generation sequencing technologies, the above mentioned attributes of the wheat genome have rendered the assembly of genomic sequences extremely difficult. (biomedcentral.com)

Both predicted proteins are highly conserved with other known homologous sequences, with the exception of two small domains present only in the Sof-RXR. (europa.eu)
At least four phylogenetically distinct groups of bacteria encode repeat proteins with the common ability to bind specific DNA sequences with a unique but conserved code. (uni-muenchen.de)
In this chapter, we describe a complete pipeline of analysis, starting from (i) the integration of information from a reference set of experimentally studied systems, (ii) the identification of conserved proteins and the construction of their HMM protein profiles, (iii) the definition and optimization of "macsy-models," and (iv) their use and online distribution as tools to search genomic data for secretion systems of interest. (bvsalud.org)
Sequence homologies between four cytoskeleton-associated proteins. (embl.de)

To test this method, a WD40 repeat-containing domain protein from Beauveria bassiana was used as reference sequence to find out a group of homologous gene sequences similar to some closely related to Verticillium dahliae. (ac.ir)

Whole exome sequencing identifies a novel compound heterozygous GFM1 variant underlying developmental delay, dystonia, polymicrogyria, and severe intellectual disability in a Pakhtun family. (nih.gov)
Methods The Deciphering Developmental Disorders study is using whole exome sequencing in family trios to investigate children with severe, sporadic, undiagnosed developmental delay. (bmj.com)

These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. (kb.se)
Comparison of the three predicted human MTG8-related polypeptides to their Drosophila counterpart (nervy) highlights four separate regions of sequence conservation that may correspond to distinct domains. (embl-heidelberg.de)

The current virus outbreak reveals only minor genetic variations compared to strains first collected in the 1970s. (bignewsnetwork.com)
Registration of 252 sequenced sorghum mutants as a community reverse genetic resource. (usda.gov)
Integrative analyses of similar to 500 mice and similar to 1,000 patients revealed a common MAPK-MYC genetic pathway that accelerated time to progression from precursor states across genetically heterogeneous MM. MYC-dependent time to progression conditioned immune evasion mechanisms that remodeled the BM microenvironment differently. (unav.edu)
Transposable elements (TEs) are mobile genetic sequences that comprise around 50% of our genomic DNA. (lu.se)

If these regions perform an important regulatory function, the increase in 3'-UTR length over evolutionary time suggests that conserved UTRs contribute to organism complexity. (wikipedia.org)
Evolutionary consequences associated with hybridization events have been studied at various levels such as chromosomal rearrangements, repetitive DNA sequence evolution, genome size change, and diploidization ( Hegarty and Hiscock, 2008 HEGARTY, M.J. and HISCOCK, S.J., 2008. (scielo.br)
The construction of BAC-based physical maps of individual chromosomes reduces the complexity of this allohexaploid genome, enables elucidation of gene space and evolutionary relationships, provides tools for map-based cloning, and serves as a framework for reference sequencing efforts. (biomedcentral.com)

The retrieved sequences from Genbank amino acid sequence databases were analyzed for designing degenerate primers. (ac.ir)

Genomic Investigation Reveals Highly Conserved, Mosaic, Recombination Events Associated with Capsular Switching among Invasive Neisseria meningitidis Serogroup W Sequence Type (ST) - 11 Strains. (cdc.gov)
In addition, we sequenced 99 ospC flanking sequences from different lineages and compared the complete cp26 sequences of 11 strains as well as the cp26 bbb02 loci of 56 samples. (cdc.gov)

The high-quality physical map constructed in this study paves the way for the assembly of a reference sequence, from which breeding efforts will greatly benefit. (biomedcentral.com)

When conserved regulatory transposable elements are active in a genome, they can introduce new promoter regions, disrupt existing regulatory sites, or, if inserted into transcribed regions, alter splicing patterns. (wikipedia.org)

molecular studies are difficult due to the absence of genome sequence data for any cephalopod. (europa.eu)

Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. (nih.gov)

Phylogenetic footprinting analysis reveals several conserved sequence patches several hundred bp long, in comparisons between Strongylocentrotus purpuratus and Lytechinus variegatus of the genomic region surrounding the blimp1/krox locus. (caltech.edu)

Some of the most highly conserved noncoding regions are found in the untranslated regions (UTRs) at the 3' end of mature RNA transcripts, rather than in the introns. (wikipedia.org)
LINE-encoded reverse transcriptase is not highly sequence-specific. (wikipedia.org)
PURA encodes Pur-α, a highly conserved multifunctional protein that has an important role in normal postnatal brain development in animal models. (bmj.com)
The Multiple allignments of the selected sequences revealed two highly conserve motif regions of amino acids that enabled us to design a degenerate primers. (ac.ir)
A helix initiation motif and a helix termination motif segment can be found at either end of the alpha-helical rod and are highly conserved in sequence between keratins. (medscape.com)
By means of DNA sequencing of a large sample collection of the pathogen from across the United States, we studied the gene for the bacterium's highly diverse OspC protein, protective immunity against which develops in animals. (cdc.gov)

Relative levels of gene expression throughout development were determined by quantitative polymerase chain reaction (PCR) analysis and in cases where sufficient specific gene sequence was acquired, ribonucleic acid (RNA) probes were generated to evaluate the spatial expression patterns during the period of organogenesis. (europa.eu)
Comparatively short sequences (several hundred to several thousand base pairs, depending on thespecies) upstream or downstream of the transcription start site often play a major role in the regulation of gene expression. (biomedcentral.com)
Epigenetic control of gene expression lasts through multiple cell divisions without alterations in primary DNA sequence and can occur via mechanisms that include histone modification and DNA methylation. (stanford.edu)
Noncoding RNA sequences can regulate gene expression via interactions with epigenetic and other control mechanisms. (stanford.edu)
Suspected resis-tant populations collected across Japan were investigated for herbicide sensitivity and ALSgene sequences, followed by functional characterization and ALS gene expression analysis. (weedscience.org)

Degenerate primers-based polymerase chain reaction (PCR) are commonly used for isolation of unidentified gene sequences in related organisms. (ac.ir)
For designing the degenerate primers, we propose the use of local alignment search method for searching the conserved regions long enough to design an acceptable primer pair. (ac.ir)
Forward and reverse degenerate primers for amplification of the related WD40 repeat-containing domain gene were designed from an alignment of the translated sequences from some other fungi. (ac.ir)
BES analyses identified 6,848 simple sequence repeats (SSRs), of which 3,854 had high quality flanking sequences for PCR primers design. (biomedcentral.com)

In the budding yeast Saccharomyces cerevisiae , there are over 400 origins of DNA replication located on 16 chromosomes and they can function as autonomously replicating sequences (ARSs) when inserted into a plasmid 19 . (nature.com)
In the absence of a finished quality genome sequence, insights into wheat genome structure and function have been accumulating through survey sequencing of individual chromosomes or chromosome-specific Bacterial Artificial Chromosome (BAC) libraries. (biomedcentral.com)

In the present study, we adopted MO calculations to investigate interactions between FMs and eight DNA hexamers with sequences such as AAAAAA, TTTTTT, AAATTT, TTTAAA, ATATAT, TATATA, GGGGGG and CCCCCC. (int-conf-chem-structures.org)
A complex with the substrate analogue N-acetyl-glucosamine was refined to 2.25 A resolution, revealing interactions of an aspartic acid and three histidines, all conserved in the NodB homology domain, with the ligand. (rcsb.org)

Here, we characterize epigenetic features of active promoter proximal regions and candidate distal regulatory elements to construct high-resolution chromatin interaction maps for maize via long-read chromatin interaction analysis by paired-end tag sequencing (ChIA-PET). (nature.com)

Using structure-guided sequence analysis we uncover previously uncharacterized CIF peptides conserved among higher plants. (unige.ch)
Gene reduction analysis revealed that the gene deletion processes are under selective pressure, and many of the inactivations are probably related to the organism's interaction with its host environment. (asm.org)
Analysis of gene regulatory networks revealed IRF1 and STAT1 were key drivers of the LPS-induced IFN-signaling response in lymphocytes with a potential developmental role for IRF7 regulation. (bvsalud.org)
The work presented in this thesis focuses on the bioinformatic methods for a TE-centric analysis of next- and third-generation sequencing technologies. (lu.se)

The S. cerevisiae ORC binds to specific DNA sequences throughout the cell cycle but becomes active only when it binds to the replication initiator Cdc6. (nature.com)

The mechanism of DNA binding is conserved. (uni-muenchen.de)
The PdaA structure provides a template for interpreting the wealth of sequence data on family 4 carbohydrate esterases in a structural context and represents a first step towards understanding the reaction mechanism of this family of enzymes. (rcsb.org)

These sequences are of interest for their potential to regulate gene production. (wikipedia.org)

Investigations of the mechanisms revealed that TLR3 activation of iMg by poly (I:C) induced the expression of both type I and type III IFNs. (bvsalud.org)

Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. (kb.se)

The discovery of specific repeat elements will facilitate analyses of sequence content (e.g. for SNPs discovery and for transcriptome characterization) and future genome sequence assemblies. (biomedcentral.com)

The structure reveals that Cdc6 contributes to origin DNA recognition via its winged helix domain (WHD) and its initiator-specific motif. (nature.com)
We reveal that repeated ecological and morphological diversification along a common environmental axis is associated with both genome-wide allele frequency shifts and a specific, larger effect, locus, associated with the gene edar . (biorxiv.org)
As the programs for the simulations such as Amber, CHARMM, BOSS and so on have good parameters for DNA, they succeeded in producing dynamic features of complexes of DNA and fluorescent materials (FMs).However, it is necessary to always make parameters for each FM when new FMs are designed for a specific DNA sequence. (int-conf-chem-structures.org)
A comparison of the putative substrate binding site of homologs within the brassicaceous-specific, glucosinolate-transporting clade with the non-brassicaceous-specific, non-glucosinolate-transporting UMAMIT32 clade identified 11 differentially conserved sites. (frontiersin.org)
However, such an approach offers little information as to the specific function of the conserved sequences. (biomedcentral.com)
Working together with others I was able to show that repeats from each group of TALE-likes mediate sequence specific DNA binding, revealing a conserved code in each case. (uni-muenchen.de)
Here, we provide a chromosome-specific view into the organization and evolution of the D genome of bread wheat, in comparison to one of its ancestors, revealing recent genome rearrangements. (biomedcentral.com)
The most NH2-terminal of these is proportionately more conserved among the human polypeptides, presumably due to specific structural/functional constraints. (embl-heidelberg.de)
Regardless of the specific model realization, we can imagine that a new conserved quantum number is discovered at LHC. (lu.se)

Intron sequences may be conserved, often because they contain expression regulating elements that put functional constraints on their evolution. (wikipedia.org)

Quantitative biochemical comparisons reveal that GSO1/SGN3-CIF2 represents one of the strongest receptor-ligand pairs known in plants. (unige.ch)

The substituted amino acid is located within the second C2HC motif in the conserved zinc finger domain of NANOS3 and in silico molecular modelling suggests destabilization of protein-RNA interaction. (hindawi.com)
Recently, the development of with food (in particular dietary fibre, comprising more than 100 trillion mi- molecular tools and subsequently of enabling energy harvest from oth- crobes living in the intestines, the next-generation sequencing enabled erwise indigestible dietary com- mouth, the skin, the vagina, and the richness of the intestinal ecosys- pounds), interacting with cells (in- elsewhere in the body. (who.int)
MERS-CoV) via next generation sequencing (NGS) from found in Wuhan, but it would appear samples prepared for cultured virus or directly from samples received from molecular testing could be handled as would samples of several pneumonia patients. (who.int)

Here, we provide a step-by-step protocol to (1) identify whether host genome projects contain reads from associated Wolbachia and (2) isolate/retrieve the Wolbachia reads from the rest of the sequenced material. (bvsalud.org)

The backbone dynamics of the N-terminal domain of delta subunit was studied to revealed the functionally important parts of the molecule. (xray.cz)

Enzolytics has a robust Artificial Intelligence Platform for genomic surveillance and monitoring of viral epidemiology that is used to identify conserved targets for produced Monoclonal Antibodies. (bignewsnetwork.com)
The Company's Artificial Intelligence platform has also been used to build AI-generated 3D Models of all the conserved targets. (bignewsnetwork.com)

Inspection of the results reveals that the MOLMAP descriptors do not simply correspond to a code of structural fragments. (int-conf-chem-structures.org)

I will argue that the TALE-likes represent a fascinating case of conserved structure and function in a diverse sequence space. (uni-muenchen.de)
The RNA-binding protein NANOS3 poses as an interesting candidate gene for POI since members of the Nanos family have an evolutionarily conserved function in germ cell development and maintenance by repressing apoptosis. (hindawi.com)
Changes in the SEPTIN9 gene may alter the sequence of amino acids in certain septin-9 isoforms in ways that interfere with their function. (medlineplus.gov)

A 3.0-Å crystal structure of the LRR-RK GSO1/SGN3 regulating Casparian strip formation in the endodermis reveals a large spiral-shaped ectodomain. (unige.ch)
The crystal structure ofthe CAP-Gly domain of Caenorhabditis elegans F53F4.3 protein, solved bysingle wavelength sulfur-anomalous phasing, revealed a novel protein foldcontaining three beta-sheets. (embl.de)
Crystal structures have revealed that multiple cadherin domains form Ca2+-dependent rod-like structures with a conserved Ca2+-binding pocket at the domain-domain interface. (embl.de)

The protein coding sequence of GFP was substituted for that of the second exon, 1b. (caltech.edu)

Dick C.W., Roubik D.W., Gruber K.F., Bermingham E. (2004) Long-distance gene flow and cross-Andean dispersal of lowland rainforest bees (Apidae, Euglossini) revealed by comparative mitochondrial DNA phylogeography, Mol. (apidologie.org)

We then extended these sequences in both directions using rapid-amplification of complementary deoxyribonucleic acid (c-DNA) ends (RACE) to obtain full length transcripts, all of which will be deposited in the public database GenBank. (europa.eu)
The production of Wolbachia genomic DNA free of contamination from host DNA, as required for Wolbachia-targeted sequencing, was then only possible after the amplification and extraction of a large amount of clonal Wolbachia DNA. (bvsalud.org)

A conserved glycine-rich domain, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. (embl.de)
Sequence conservation in this family has pointed to a conserved core, termed the NodB homology domain. (rcsb.org)

Case 4 was a phenotypically isolated case recruited into an undiagnosed rare disorders sequencing study. (bmj.com)

The first rainbow trout repeat elements database (INRA RT rep1.0) containing 735 putative repeat elements was developed, and identified almost 59.5% of the BES database in base-pairs as repetitive sequence. (biomedcentral.com)
Approximately 55% of the BES reads (97,846) had more than 100 base pairs of contiguous non-repetitive sequences. (biomedcentral.com)

Using RNA deep sequencing, we found that raltegravir specifically boosts the expression of anti-angiogenic factors and promotes metabolic homeostasis in FHV-1-infected cells. (microbiologyresearch.org)

DNA transposons encode a transposase protein, which is flanked by inverted repeat sequences. (wikipedia.org)

Electron microscopy revealed a suspected human influenza (2, 7-9). (who.int)

Anatomy18

Organisms17

Diseases1

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Phenomena and Processes112

Disciplines and Occupations4

Anthropology, Education, Sociology and Social Phenomena1

Information Science8

Health Care3

Genes17

Residues9

Evolutionarily conserved regions1

Whole-genome1

Genomes6

Mutations8

Motifs2

Species9

Genomic sequences2

Proteins4

Homologous1

Exome2

Drosophila2

Genetic4

Evolutionary3

Amino acid seq1

Strains2

Reference sequence1

Transposable1

Genome sequence data1

Distinct1

Phylogenetic1

Highly6

Gene expression5

Primers4

Chromosomes2

Interactions2

Regulatory elements1

Analysis4

Binds1

Mechanism2

Regulate gene1

Mechanisms1

Histone modification1

Characterization1

Specific9

Functional1

Quantitative1

Molecular3

Isolate1

Functionally1

Targets2

Structural1

Function3

Crystal3

Protein coding s1

Mitochondrial1

Amplification2

Domain2

Disorders1

Base pairs2

Found1

Inverted repeat1

Human1