• Unstable angina pectoris. (studentnow.com)
  • In this perspective, multicenter, open-label, assessor-blinded clinical trial, a total of 781 patients with biomarker negative stable or unstable angina pectoris with an indication for PCI were randomized into two groups to receive either intensified oral loading strategy (ILS) with prasugrel 60 mg or standard loading strategy (SLS) with clopidogrel 600 mg. (cardiologynownews.org)
  • Adverse cardiovascular events (composite of cardiovascular death, nonfatal myocardial infarction, resuscitated cardiac arrest, coronary revascularization, hospitalization for angina pectoris, hospitalization for congestive heart failure, fatal or nonfatal stroke or transient ischemic attack, and any new diagnosis of peripheral vascular disease) for the comparison of amlodipine vs. placebo. (acc.org)
  • In this multicenter, randomized clinical trial of amlodipine, enalapril, or placebo among patients with coronary artery disease and relatively normal blood pressures, treatment with amlodipine was associated with a reduction in the composite endpoint of cardiovascular events compared to placebo, largely driven by a reduction in coronary revascularization and hospitalization from angina. (acc.org)
  • What kinds of medical tests are used to establish the diagnosis of angina? (studentnow.com)
  • Although the risk is small, such patients have a greater chance of experiencing angina pectoris, non-fatal myocardial infarction, a need for coronary revascularization, and new diagnosis of peripheral vascular disease. (trantololaw.com)
  • An initial consultation with the patient/client's physician (cardiologist or primary care physician) is indicated to establish the diagnosis and treatment regimen for angina, which will inform subsequent dental/dental hygiene management. (cdho.org)
  • Symptoms of Angina Pectoris Diagnosis(Latin for squeezing of the chest) - is chest pain, discomfort, or tightness that occurs when an area of the heart muscle is receiving decreased blood oxygen supply. (rxharun.com)
  • 8,9 Studies have shown greater angina severity at the time of diagnosis to be associated with higher mortality rates, cardiovascular hospitalizations, coronary revascularization, and overall healthcare costs. (uscjournal.com)
  • What are the most common symptoms of angina? (studentnow.com)
  • It was known that PCI improved angina symptoms and short-term exercise performance in stable disease, but its mortality benefit and reduction of future myocardial infarction and ACS were unknown. (medicine52in52.com)
  • However, initial management with PCI did provide a time-limited improvement in angina symptoms. (medicine52in52.com)
  • Vulnerable, ACS-prone plaques have thin caps and spread outward along the wall of the coronary artery, as opposed to the plaques of stable CAD which have thick fibrous caps and are associated with inward-directed remodeling that narrows the artery lumen (and thus cause reliable angina symptoms and luminal narrowing on coronary angiography). (medicine52in52.com)
  • Finally, PCI should be considered in patients whose physical activity is limited by angina symptoms despite optimal medical therapy. (medicine52in52.com)
  • Symptoms of angina occur when the coronary arteries are narrowed or blocked by atherosclerosis or by a blood clot. (rxharun.com)
  • The Canadian Cardiovascular Society angina classification is a symptom severity scale used to assess and grade physical limitation due to symptoms. (uscjournal.com)
  • A recent study article co-authored by Matthew Watkins, M.D., professor of medicine at the University of Vermont College of Medicine, indicates that an experimental treatment designed to promote blood vessel growth and improve cardiovascular blood flow in patients with angina may have a positive treatment effect in women as opposed to men. (sciencedaily.com)
  • Patients were followed for major adverse cardiovascular events (MACEs) including death, myocardial infarction, stroke, and revascularization at 30 days and over a median follow-up period of 7.3 years and for mortality only through a median of 16.6 years. (elsevierpure.com)
  • In conclusion, appearance of LBBB or RBBB in patients presenting with angina predicts adverse long-term cardiovascular outcomes compared to patients without BBB. (elsevierpure.com)
  • Bleeding complications defined according to Bleeding Academic Research Consortium criteria ≥ 2 and non-CABG-related Thrombolysis in Myocardial Infarction major and minor bleeding, peri-PCI type 4a MI, all-cause death, cardiovascular death, any myocardial infarction, definite/probable stent thrombosis, urgent vessel revascularization, and stroke within 30 days after index PCI were considered the secondary endpoints of the study. (cardiologynownews.org)
  • Do Cardiac Rehabilitation Affect Clinical Prognoses Such as Recurrence, Readmission, Revascularization, and Mortality After AMI? (e-arm.org)
  • Absence of coronary artery disease: Cardiac ischaemia with angina pectoris can exist in the absence of significant coronary artery disease, possibly due to microcoronary dysfunction (up to 10% of patients of which a majority of women). (escardio.org)
  • The primary endpoint was major adverse cardiac events (MACE), defined as the composite of all-cause death, nonfatal myocardial infarction, or unplanned revascularization at 1 year. (uantwerpen.be)
  • For their September 11, 2006 Journal of American College of Cardiology article, Watkins and his colleagues analyzed pooled original data from the AGENT -3 and -4 trials to determine treatment effects in two subgroups, gender and older patients with severe angina. (sciencedaily.com)
  • Because nerves are extremely sensitive to hypoxia, limb paralysis or ischemic neuropathy may persist after revascularization and may be permanent. (wikipedia.org)
  • Additionally, you need to have one of these: abnormal imaging results, an abnormal stress test, or three separate ischemic episodes requiring revascularization inside a 12-month period. (kfeej.com)
  • These words aptly describe the basic clinical manifestations of angina pectoris , commonly called angina, the classic expression of ischemic heart disease. (rxharun.com)
  • OBJECTIVES The aim of this study was to investigate the clinical outcomes of patients deferred from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris (SAP) and acute coronary syndromes (ACS). (uantwerpen.be)
  • GXN tablets are composed of Danshen and Chuanxiong, with the functions of activating blood circulation, removing blood stasis, invigorating the pulse, and nourishing the heart, which are used for CHD patients with stable exertional angina Grade I or II (according to traditional Chinese medicine, it is a syndrome of heart and blood stasis with chest pain and dark purple lips and tongue). (hindawi.com)
  • It is approved as add-on therapy to conventional agents for the symptomatic treatment of patients with stable angina pectoris in whom conventional drugs have failed. (escardio.org)
  • METHODS The safety of deferral of coronary revascularization in the pooled per-protocol population (n = 4,486) of the DEFINE-FLAIR (Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation) and iFR-SWEDEHEART (Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve in Patients With Stable Angina Pectoris or Acute Coronary Syndrome) randomized clinical trials was investigated. (uantwerpen.be)
  • The trial enrolled patients with stable or unstable angina or a myocardial infarction (MI) at least 72 hours before screening if they had at least one coronary lesion with a diameter stenosis of 50%-90% and a reference vessel diameter of at least 2.5 mm. (medscape.com)
  • Some types of angina occur at rest, however, such as Prinzmetal's or variant angina. (studentnow.com)
  • Myocardial laser revascularization: the controversy and the data. (studentnow.com)
  • The need for repeated treatment of restenosis of a treated vessel remains the main limitation of percutaneous coronary revascularization. (qxmd.com)
  • The difference was due entirely to a higher rate of revascularization of the target vessel in the standard-stent group. (qxmd.com)
  • Impact of drug eluting stents on target vessel revascularization. (pcronline.com)
  • The primary endpoints were All-cause death, any myocardial infarction (MI), stent thrombosis, urgent vessel revascularization, or stroke within 30 days. (cardiologynownews.org)
  • Target vessel revascularization (2.4% vs 3.5%) and stent thrombosis (0.3% vs 0.5%) trended lower. (medscape.com)
  • Ever since William Heberden's seminal description of angina pectoris in 1772, [ 1 ] attempts have been made to find an effective treatment of this condition. (medscape.com)
  • Based on these findings, a Phase 3 clinical trial titled AWARE (Angiogenesis in Women with Angina pectoris who are not candidates for Revascularization) was launched in August 2007. (sciencedaily.com)
  • We also analyzed a composite clinical end point consisting of death, myocardial infarction, and percutaneous or surgical revascularization at 1, 6, and 12 months. (qxmd.com)
  • CONCLUSIONS: Coenzyme Q10 therapy in angina and hypertension cannot be substantiated until additional clinical trials demonstrate consistent beneficial effects. (drlauda.at)
  • The major clinical characteristic of angina is chest pain. (rxharun.com)
  • Patients were stratified according to revascularization decision making on the basis of iFR or FFR and to clinical presentation (SAP or ACS). (uantwerpen.be)
  • The subject concerning the necessity of complete myocardial revascularization, changes of anatomy and physiology of the heart, clinical state of patients with a low left ventricular ejection fraction after endovascular intervention has not been sufficiently explored. (angiolsurgery.org)
  • The essential clinical feature of mixed angina is a substantial variation in the degree of physical activity that induces angina. (wikidoc.org)
  • Angina is defined as pain or pressure in the chest, beneath the breastbone, that occurs when the heart is not getting enough oxygen. (studentnow.com)
  • Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)
  • Patients/clients who have stable angina (i.e., chest pain that occurs in a predictable pattern) can generally safely receive routine outpatient dental/dental hygiene care. (cdho.org)
  • Angina decubitus - Is angina that occurs spontaneously during rest. (rxharun.com)
  • In such cases, angina can result whether atherosclerosis is present or not. (msdmanuals.com)
  • Additional prespecified secondary end points included all-cause mortality and the incidence of revascularization in vessels that had undergone previous stent placement. (acc.org)
  • rather, these therapies are for many a preparation for ultimate revascularization, to preserve myocardium and minimize periprocedural complications. (elsevierpure.com)
  • If angina is not relieved, unmet myocardial oxygen demand increases further, making MI more likely. (rxharun.com)
  • Long-term outcomes of unselected patients with angina pectoris and bundle branch block (BBB) on initial electrocardiogram are not well established. (elsevierpure.com)
  • The SASSICAIA (Strategies of Loading With Prasugrel Versus Clopidogrel in PCI-Treated Biomarker Negative Angina) trial investigated w hether stronger platelet inhibition by an intensified oral loading strategy (ILS) with prasugrel prior to PCI would affect outcomes among biomarker-negative stable and unstable angina patients undergoing elective PCI. (cardiologynownews.org)
  • To determine the best combination of parameters that would improve the diagnostic performance of exercise testing, coronary angiography plus exercise testing were done on 112 patients with angina pectoris and normal electrocardiogram. (who.int)
  • All patients before and 6 months after the intervention underwent echocardiographic examination with the measurement of the left ventricular ejection fraction, stroke volume, end-diastolic volume and assessment of the functional class of angina pectoris. (angiolsurgery.org)
  • A reported 8.9 million people in the United States, including 4.6 million women, live with chronic angina, the debilitating chest pain, squeezing or pressure experienced by people with coronary heart disease. (sciencedaily.com)
  • UVM is one of more than two dozen centers in the country currently participating in this trial, which aims to enroll approximately 300 women with chronic angina who are not candidates for conventional bypass surgery or angioplasty in order to more closely examine the effects of angiogenic therapy on this population of patients. (sciencedaily.com)
  • The maximum recommended dose of Norvasc to treat hypertension or angina pectoris in adults is 10mg per day. (happyfamilydrugstore.com)
  • The materials about essential hypertension and chronic stable angina, provided in the review of Norvasc, are meant for information purposes only and are not intended to replace treatments or medical advice of the health care professional. (happyfamilydrugstore.com)
  • Publication Types: Review Review, Tutorial PMID: 10556981 [PubMed - indexed for MEDLINE] 1: Pharmacotherapy 2001 Jul;21(7):797-806 Role of coenzyme Q10 in chronic heart failure, angina, and hypertension. (drlauda.at)
  • The purpose of this review is to provide recommendations regarding the safety, efficacy, and dosing of CoQ10 in the management of chronic heart failure (CHF), angina, and hypertension. (drlauda.at)
  • is clinically worsening angina (eg, angina at rest or with increasing frequency and/or intensity of episodes). (msdmanuals.com)
  • Many patients continue to have episodes of angina post-operatively but the frequency of those episodes should decrease. (umn.edu)
  • Patients should be asked about the frequency of angina, severity of pain, and number of nitroglycerin pills used during episodes. (medscape.com)
  • Stable angina - is characterized by regular episodes of pain triggered by physical exercise or activity, smoking, eating large meals, or extreme temperatures. (rxharun.com)
  • Angina pectoris is not a disease, but rather a symptom of inadequate oxygen supply to the heart, which can result from a variety of conditions. (studentnow.com)
  • Nocturnal angina - May occur if a dream causes striking changes in respiration, pulse rate, and BP. (rxharun.com)
  • Nocturnal angina may also be a sign of recurrent LV failure, an equivalent of nocturnal dyspnea. (rxharun.com)
  • This group of patients may also experience nocturnal angina on certain occasions. (wikidoc.org)
  • This is a specific form of unstable angina that can occur at any time (no trigger event causes it to happen). (rxharun.com)