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AdenosineReceptor, Adenosine A2AReceptor, Adenosine A1Serotonin Uptake InhibitorsAdenosine DeaminaseReceptor, Adenosine A3Receptor, Adenosine A2BAdenosine KinaseReceptors, Adenosine A2Adenosine A2 Receptor AgonistsAdenosine A2 Receptor AntagonistsReceptors, Purinergic P1Adenosine A1 Receptor AntagonistsAdenosine A1 Receptor AgonistsFluoxetinePurinergic P1 Receptor AntagonistsCitalopramParoxetineXanthinesPurinergic P1 Receptor AgonistsAdenosine MonophosphateAdrenergic Uptake InhibitorsAdenosine-5'-(N-ethylcarboxamide)Neurotransmitter Uptake InhibitorsAntidepressive AgentsTheophyllineAdenosine A3 Receptor AntagonistsReceptors, PurinergicAntidepressive Agents, Second-GenerationAntidepressive Agents, TricyclicFluvoxamineAdenosine A3 Receptor Agonists2-ChloroadenosinePhenethylaminesSerotoninPhenylisopropyladenosineInosineSertraline5'-NucleotidaseSerotonin Plasma Membrane Transport ProteinsCyclic AMPCyclohexanolsAdenosine TriphosphatasesTubercidinDesipramineAdenine NucleotidesDose-Response Relationship, DrugNucleoside DeaminasesNorepinephrine Plasma Membrane Transport ProteinsClomipramineRats, Sprague-DawleyCoformycinNorepinephrineDipyridamoleTheobrominePropylaminesMicrodialysisPentostatinAdenosine PhosphosulfateDopamine Uptake InhibitorsCyclobutanesSerotonin AntagonistsMaprotilinePurinesKineticsThioinosineReceptors, SerotoninTriazinesAdenineDepressive DisorderRats, Wistarp-ChloroamphetamineReceptors, Serotonin, 5-HT18-Hydroxy-2-(di-n-propylamino)tetralinDeoxyadenosinesSerotonin SyndromeDepressive Disorder, MajorDopamineTime Factors1-NaphthylamineSerotonin Receptor AgonistsCalciumPurinergic AntagonistsThiophenesFenfluramineAminophyllineCyclopropanesVasodilator AgentsExtracellular SpaceBiogenic MonoaminesNucleoside Transport ProteinsHypoxanthineDopamine Plasma Membrane Transport ProteinsNucleotidasesNorethandroloneHypoxanthinesGuinea PigsBehavior, AnimalBrainTriazoles
ReceptorsInhibitorInhibits adenosine reuptakeTriphosphateNeurotransmittersCyclic adenosine monNeurotransmitter adenosineLevel of adenosineConcentrations of adenosineInhibitionReceptorInhibitorsCannabidiolEndogenousMoleculeEnhancesCaffeineENT1ATPaseSerotoninIncreasesInfluencesDepressionBodyEffectsEnergyAffect
Receptors13
  • CBD oil inhibits A2A adenosine receptors leading to clarity in the person's mind. (tcpjusticedenied.org)
  • Adenosine receptors are closely associated with dopamine receptors and form heteromer s with them. (adxs.org)
  • At the same time, adenosine modulates striatal DA release by stimulating glutamate release at adenosine receptors in the striatum , which increases dopamine levels. (adxs.org)
  • Part of this adenosine is discharged from the cell and binds to adenosine receptors of neighboring cells, which is supposed to compensate for the disturbed balance between energy consumption and energy supply. (adxs.org)
  • By binding to same receptors adenosine would bind to, CBD may inhibit adenosine reuptake, which helps it accumulate more quickly and makes you feel sleepy sooner. (cbdcliniccare.com)
  • By doing this, the level of adenosine in the brain increases, which impacts adenosine receptors in a way that significantly reduces inflammation within the body. (midorisobsessions.com)
  • This, in turn, impacts adenosine receptors as well as plays a major function in reducing swelling in the body. (insideofmypurse.com)
  • This, consequently, effects adenosine receptors as well as plays a significant duty in decreasing swelling in the body. (insideofmypurse.com)
  • When the accessibility of adenosine rises in the mind, it impacts the A1A and also A2A adenosine receptors which are in charge of expressions of anxiety. (moremulher.com)
  • When the schedule of adenosine rises in the mind, it influences the A1A and A2A adenosine receptors which are responsible for expressions of anxiousness. (moremulher.com)
  • Caffeine is an antagonist at adenosine receptors, which tells us that adenosine is important in the regulation of vigilance. (heresy.is)
  • CBDalso behaviors by means of distinct receptor-independent pathways-like, simply by slowing the "reuptake" of endogenic chemicals (such while a nandamide as well as adenosine) and beautifying or inhibiting these holding behavior about several G-protein joined together receptors. (thewhitegoddess.us)
  • Traditional stimulants, such as amphetamines, work through increasing wake-promoting catecholamines, whereas caffeine blocks sleep-promoting adenosine receptors. (medlink.com)
Inhibitor9
  • An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs). (wikipedia.org)
  • Acadesine Acetate Barbiturates Benzodiazepines Calcium channel blockers Carbamazepine Carisoprodol Cilostazol Cyclobenzaprine Dilazep Dipyridamole Estradiol Ethanol Flumazenil Hexobendine Hydroxyzine Indomethacin Inosine KF24345 Meprobamate Nitrobenzylthioguanosine Nitrobenzylthioinosine Papaverine Pentoxifylline Phenothiazines Phenytoin Progesterone Propentofylline Propofol Puromycin R75231 RE 102 BS Soluflazine Toyocamycin Tracazolate Tricyclic antidepressants Adenosinergic Reuptake inhibitor SenGupta DJ, Unadkat JD (2004). (wikipedia.org)
  • Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor. (wikidoc.org)
  • CBD acts as a reuptake inhibitor to increase the levels of anandamide available. (tcpjusticedenied.org)
  • ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory. (axonmedchem.com)
  • Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor. (axonmedchem.com)
  • It is also a potent inhibitor of adenosine reuptake, which could be the node of its action. (cannabidiol.ooo)
  • Here, we assessed the long-term effects of exposure to fluoxetine (FLX), a selective serotonin reuptake inhibitor, during adolescence on behavioral reactivity to emotion-eliciting stimuli. (jneurosci.org)
  • The researchers are believing that this herb does not only act as the 5-HT reuptake inhibitor and PDE4 inhibitor but it is also promoting the release of monoamines and then improving the behavior and mood. (route-nature.com)
Inhibits adenosine reuptake2
Triphosphate4
  • a component of adenosine triphosphate and adenosine diphosphate. (adxs.org)
  • This protein uses energy from a molecule called adenosine triphosphate (ATP) to transport charged atoms (ions) into and out of cells. (medlineplus.gov)
  • Adenosine triphosphate (ATP) breaks down as your brain burns carbohydrate for energy, and adenosine gradually accumulates in the brain. (cbdcliniccare.com)
  • Creatine supplementation increases the levels of phosphocreatine (PCr) in muscles, which is used by creatine kinase to regenerate Adenosine triphosphate ( ATP ) in skeletal muscle . (physio-pedia.com)
Neurotransmitters3
  • The reuptake of neurotransmitters is carefully controlled to ensure that signals are sent and received accurately throughout the nervous system. (medlineplus.gov)
  • More adenosine binding to neurons inhibits the release of neurotransmitters, slowing down brain activity, helping you feel calmer, and inducing sleep. (cbdcliniccare.com)
  • Several research studies have considered the effects of CBD on pain management and all have reached the conclusion that CBD is able to reduce pain signals and sensation by stimulating the reuptake of the neurotransmitters adenosine. (hempingus.com)
Cyclic adenosine mon2
Neurotransmitter adenosine1
Level of adenosine1
  • Through this mechanism, the increased level of adenosine after sleep deprivation could affect the light sensitivity of the circadian clock. (adxs.org)
Concentrations of adenosine2
  • This in turn leads to increased extracellular concentrations of adenosine and therefore an increase in adenosinergic neurotransmission. (wikipedia.org)
  • Your body metabolizes adenosine as you sleep, and some time later, low concentrations of adenosine help you wake up and the process starts again. (cbdcliniccare.com)
Inhibition2
  • By preventing ADO phosphorylation, ADK inhibition increases intracellular ADO concentrations, altering the equilibrium of the bidirectional transport systems responsible for ADO reuptake with the net effect of increasing the local concentration of ADO in the extracellular compartment. (axonmedchem.com)
  • Adenosine reuptake inhibition reduces diabetes-induced glomerular hyperfiltration via the adenosine A2 a receptor. (uu.se)
Receptor1
  • Due to indirect modulation of dopamine transmission, adenosine receptor antagonists may be useful in either treating cocaine use or improving disrupted cognitive-behavioral functions associated with chronic cocaine use. (omicsonline.org)
Inhibitors2
  • Selective serotonin reuptake inhibitors (SSRIs) are recommended by many doctors to increase these levels. (tcpjusticedenied.org)
  • Evidence suggests that combined administration of inhibitors of monoamine reuptake and phosphodiesterase type 4 allows a highly effective therapeutic action. (zhihuiya.com)
Cannabidiol2
  • Cannabidiol molecules are recognized to stop the reuptake of adenosine in the body, and by doing so, they elevate your mood. (moremulher.com)
  • Cannabidiol particles are known to avoid the reuptake of adenosine in the body, as well as by doing so, they boost your mood. (moremulher.com)
Endogenous1
  • Adenosine (ADO) is an endogenous homeostatic inhibitory neuromodulator that reduces cellular excitability at sites of tissue injury and inflammation. (axonmedchem.com)
Molecule1
  • CBD may also inhibit the reuptake of anandamide, a neurotransmitter known as the "bliss molecule," allowing it to stay longer in the brain and positively impacting mood. (stophavingaboringlife.com)
Enhances2
  • CBD likewise serves as a reliable neurotransmitter named 'adenosine reuptake prevention' that enhances the function of adenosine hormone in the mind. (insideofmypurse.com)
  • CBD additionally functions as an efficient neurotransmitter called 'adenosine reuptake prevention' that enhances the feature of adenosine hormone in the brain. (insideofmypurse.com)
Caffeine1
  • To compare and contrast the stimulant effects of adenosine antagonism to direct dopamine stimulation, we administered 150 mg and 300 mg caffeine, 20 mg amphetamine, and placebo to cocaine-dependent vs. healthy control subjects, matched on moderate caffeine use. (omicsonline.org)
ENT11
ATPase2
  • Additionally, Na+/K+ ATPase helps regulate a process called neurotransmitter reuptake. (medlineplus.gov)
  • Muscle tissue [H+] may depress muscle tissue function and result in fatigue, such as for example inhibiting myofibrillar adenosine triphosphatase (ATPase), inhibiting glycolytic price, reducing crossbridge activation by inhibiting Ca2+ binding to troponin C competitively, and reducing Ca2+ re-uptake by inhibiting the sarcoplasmic ATPase [7]. (baxkyardgardener.com)
Serotonin1
Increases1
  • Creatine binds to PEG, which functions as a delivery system and increases the reuptake efficiency and ergogenic effects during exercise. (physio-pedia.com)
Influences1
  • The physiological purpose behind this may possibly be mainly because of the connection among CBD and the reuptake of adenosine, which influences the rhythm of the heart. (thanhthinhviet.vn)
Depression1
Body1
  • Adenosine is found in almost all body cells. (adxs.org)
Effects1
  • Are the 'off-target' effects of ticagrelor in blocking RBC adenosine reuptake important in explaining its mortality benefit? (acc.org)
Energy1
  • Among other things, adenosine is used for autoregulation in the event of an imminent lack of energy in the cell (e.g. when the cell's performance is overloaded or when there is a lack of oxygen): If the ATP content in a cell drops, more adenosine is produced as a hydrolysis product. (adxs.org)
Affect1
  • These preliminary data raise the possibility that adenosine antagonists may affect cocaine-dependent and non-dependent subjects differently. (omicsonline.org)