• Age younger than 65 years, hypoalbuminemia, a need for intensive respiratory or vasopressor support (IRVS), and high serum C-reactive protein (CRP) levels are independent risk factors for the development of bacteremia in patients with pneumococcal community-acquired pneumonia (CAP), according to an article published in BMC Pulmonary Medicine . (infectiousdiseaseadvisor.com)
  • Controversies exist regarding the prognostic impact of a history of human immunodeficiency virus (HIV) infection on community-acquired pneumonia. (louisville.edu)
  • Mycoplasma pneumoniae has become the leading cause of paediatric community-acquired pneumonia in countries where pneumococcal vaccination is included in the national immunisation programme, including Singapore. (annals.edu.sg)
  • This study found that flu vaccination appears to offer little protection from community acquired pneumonia (CAP), a common complication of flu, for relatively healthy, elderly people who do not live in institutions. (zana.com)
  • This study aimed to determine whether community-acquired pneumonia (CAP) had a metabolic profile and whether this profile can be used for disease severity assessment. (biomedcentral.com)
  • Community-acquired pneumonia (CAP) is a major cause of infection-associated death worldwide, with an incidence of 30-50% in adults [ 1 ]. (biomedcentral.com)
  • The most frequently detected viruses were influenza A virus (44%), followed by rhinovirus (19%), influenza B (13%), and adenovirus (6%) in community-acquired pneumonia (CAP) patients. (accjournal.org)
  • Community-acquired pneumonia (CAP) is typically caused by bacteria, such as Streptococcus pneumoniae , Hemophilus influenzae , Staphylococcus aureus , and Gram-negative bacilli. (accjournal.org)
  • In the Netherlands, the 7-valent pneumococcal conjugate vaccine (PCV-7) was implemented in a 3+1-dose schedule in the national immunization program for infants born after April 1, 2006. (cdc.gov)
  • Before the availability of conjugate pneumococcal vaccine, 3-5% of children aged 3-36 months who had a fever higher than 39°C and no source of infection were bacteremic. (medscape.com)
  • Analysis of IBI in children with SCD in a post-13-valent pneumococcal vaccine era is limited. (bvsalud.org)
  • CONCLUSIONS: In a post-13-valent pneumococcal vaccine era, Salmonella was the leading cause of bacteremia in IBI in children with SCD in Europe. (bvsalud.org)
  • The 23-valent pneumococcal polysaccharide vaccine (PPV23) has been recommended to risk-groups and adults aged ≥65 years since 1996. (biomedcentral.com)
  • The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in the childhood immunization program in July 2006, and was replaced by the 13-valent vaccine (PCV13) in 2011. (biomedcentral.com)
  • These are the first national data available on IPD in Australia and will assist in evaluating the impact of the newly introduced conjugate vaccine and guide overall pneumococcal vaccine strategies. (health.gov.au)
  • This study compared the rates of very severe pneumonia and all-cause meningitis hospitalization and death, before and after introduction of conjugate Hib vaccine, and reports the results of the 2010 bacterial meningitis surveillance. (who.int)
  • For each year of the study (2000, 2001 and 2002), the researchers were interested in whether or not the participants who contracted pneumonia had been given that year's influenza vaccine. (zana.com)
  • Pneumococcal bacteremia was termed "pneumococcal fever" during the 1970s and 1980s, when S pneumoniae was recovered in approximately 5% of blood cultures from young febrile children with mild upper respiratory tract changes (see the table below). (medscape.com)
  • Severe infections, predominantly meningitis, occur in fewer than 6% of pneumococcal occult bacteremia cases-a figure that is much lower than the 50% reported with meningococcal bacteremia and the 20% reported with H influenza . (medscape.com)
  • The identification of patients at risk for bacteremia and the formulation of strategies to prevent secondary complications (eg, meningitis, pneumonia, septic arthritis, osteomyelitis , and cellulitis) remain important aspects of general pediatric practice. (medscape.com)
  • For patients with focal infection and pneumococcal bacteremia, treatment of the focal infection and monitoring for improvement are standard. (medscape.com)
  • For outpatients with proven pneumococcal bacteremia, reevaluation of their clinical status and identification of any new focus of infection is essential. (medscape.com)
  • Occult pneumococcal bacteremia is most common in children aged 3-36 months, an age at which children no longer have maternal IgG but have not yet developed their own protective antibodies. (medscape.com)
  • Using logistic regression models, Yasuyoshi Washio of the department of respiratory medicine at Saiseikai Fukuoka General Hospital, Fukuoka, Japan, and colleagues retrospectively analyzed data from 389 patients hospitalized with pneumococcal CAP between April 2007 and August 2015 at Kurashiki Central Hospital, Okayama, Japan, to determine risk factors for pneumococcal bacteremia . (infectiousdiseaseadvisor.com)
  • 20 mg/dL as independent risk factors for the development of pneumococcal bacteremia. (infectiousdiseaseadvisor.com)
  • Washio Y, Ito A, Kumagai S, Ishida T, Yamazaki A. A model for predicting bacteremia in patients with community-acquired pneumococcal pneumonia: a retrospective observational study . (infectiousdiseaseadvisor.com)
  • Prediction of mortality in children with pneumonia-related bacteremia is necessary for providing timely care and treatment. (highwire.org)
  • This study aims to develop and validate a nomogram and compare it with Pediatric Risk of Mortality III (PRISM III), Brighton Pediatric Early Warning Score (Brighton PEWS) and Pediatric Critical Illness Score (PCIS), which are widely used in predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • This retrospective study collected clinical data of hospitalized children with pneumonia-related bacteremia in Chongqing, China (January 2013-May 2019). (highwire.org)
  • The nomogram was compared with PRISM III, PEWS and PCIS in accuracy and clinical benefits in predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • In conclusion, a nomogram-illustrated model incorporating TTFP, ALB and LDH for predicting in-hospital mortality in children with pneumonia-related bacteremia at the early stage was established and validated. (highwire.org)
  • There is no predictive model for predicting in-hospital mortality in children with pneumonia-related bacteremia at the early stage. (highwire.org)
  • Laboratory indexes including time to first positivity of blood cultures (TTFP), serum albumin (ALB) and lactate dehydrogenase (LDH) were closely related to in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • The nomogram including TTFP, ALB and LDH was established for predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • This nomogram-illustrated model may be a new approach to predicting in-hospital mortality in children with pneumonia-related bacteremia. (highwire.org)
  • Young children and elderly persons are at particularly high risk for pneumococcal infection ( 1 ). (cdc.gov)
  • Therefore we retrospectively assessed morbidity and mortality due to pneumonia after discharge in 573 consecutive patients admitted to hospital for pneumonia, gastrointestinal infection, renal infection, or erysipelas. (nih.gov)
  • The main risk factors for a severe IBI were a previous IBI and pneumococcal infection (17 Sp/51 cases). (bvsalud.org)
  • Electronic medical records of patients with M. pneumoniae infection were retrospectively reviewed after informed consent was obtained. (annals.edu.sg)
  • Antibiotic combination therapy has been reported to improve outcomes for patients with bacteremic pneumococcal CAP. (infectiousdiseaseadvisor.com)
  • Pneumococcal vaccination after hospital treatment for an episode of pneumonia might be a cost-effective means of preventing disease in this group. (nih.gov)
  • The authors suggest that this may be because of poorer pneumococcal vaccination rates among younger patients in Japan. (infectiousdiseaseadvisor.com)
  • The study is limited by the inability to determine pneumococcal serotype or vaccination status and by its small size and retrospective design. (infectiousdiseaseadvisor.com)
  • RÉSUMÉ Le vaccin contre Haemophilus influenzae type b (Hib) a été inclus dans le programme de vaccination du Yémen en 2005. (who.int)
  • When the researchers took into account all the factors they believed may have influenced the outcome including age, sex, asthma, smoking, antibiotics for lung conditions and previous pneumonia, they found that there was no significant effect of vaccination on the risk of CAP in the participants. (zana.com)
  • We serotyped 2,552 invasive pneumococcal isolates from throughout the Netherlands, covering 25% of the country's population. (cdc.gov)
  • Invasive pneumococcal disease (IPD) is responsible for significant mortality and morbidity worldwide. (biomedcentral.com)
  • Invasive pneumococcal disease (IPD) and sepsis are responsible for substantial morbidity and mortality worldwide with about 2 million deaths each year [ 4 ]. (biomedcentral.com)
  • Invasive pneumococcal disease (IPD) is defined as a clinical condition in which S. pneumoniae is isolated from a normally sterile site, e.g. blood, cerebrospinal fluid or pleural fluid. (health.gov.au)
  • It is a leading cause of otitis media, pneumonia, bacteraemia, meningitis and a less frequent cause of other conditions including septic arthritis and mastoiditis. (health.gov.au)
  • Pneumonia is an infectious disease that affects lung parenchyma, resulting in the hosts' inflammatory reaction to microorganisms, and it ranks the first among the causes of death in patients with infectious diseases over 65, with 12%-40% mortality rates based on whether they admit the intensive care unit (ICU) [ 1 ]. (accjournal.org)
  • We retrospectively analyzed the clinical characteristics and outcomes of patients subsequently admitted to AMITA Health Saint Francis Hospital between March 1 and June 30, 2020, with documented SARS-CoV-2 and S. pneumoniae coinfection. (medscimonit.com)
  • However, hospitalization and death for very severe pneumonia improved only modestly, and there was evidence of a decreasing but non-significant trend indicting that very severe pneumonia was a non-specific endpoint with multi-etiologies (both viral and bacterial). (who.int)
  • METHODS: Twenty-eight pediatric hospitals from 5 European countries retrospectively collected IBI episodes in SCD children aged 1 month to 18 years between 2014 and 2019. (bvsalud.org)
  • METHODS: From Jan 2022 to May 2022, we retrospectively included hospitalized patients tested positive by nasopharyngeal SARS-CoV-2 PCR. (bvsalud.org)
  • We conducted an evaluation of the operational performance and costs of this real-life project.MethodsEffectiveness outcomes (syndromic cure rates of STIs) were obtained by retrospectively analysing patients' records. (ox.ac.uk)
  • Since the 1970s, large outbreaks of severe pneumococcal disease caused by penicillin resistant organisms occurred in South Africa and Papua New Guinea and subsequently increased rates of penicillin resistance in pneumococci have been documented worldwide. (health.gov.au)
  • A quarter to a third of pneumonia and 27.3% of severe pneumonia in children are caused by bacteria. (highwire.org)
  • Although elderly patients who are admitted to hospital for any disease have a higher risk of pneumonia subsequently, whether those treated in hospital for pneumonia are at even greater risk is unknown. (nih.gov)
  • Pneumococcal pneumonia in HIV patients. (louisville.edu)
  • The aim of our work was to analyze and compare the clinical presentation, radiological findings and progression of pneumococcal pneumonia in patients infected with and not infected with HIV. (louisville.edu)
  • All patients had pneumonia confirmed on imaging and a nonspecific increase in markers of inflammation. (medscimonit.com)
  • Patients with positive blood cultures were registered prospectively by the microbiology laboratory and clinical variables were registered retrospectively from patients' hospital records. (biomedcentral.com)
  • We retrospectively conducted a cohort study from three multicenter randomized controlled trials enrolling consecutive patients requiring central venous catheterization. (springeropen.com)
  • Patients diagnosed with PBM were enrolled retrospectively at 13 children's hospitals in China from 2016 to 2018 and were screened based on a review of cerebrospinal fluid (CSF) microbiology results. (biomedcentral.com)
  • Les étudiants en année de doctorat affectés dans le service de médecine interne étaient responsables de la gestion quotidienne du CTE sous la supervision des spécialistes en médecine interne Ce service était subdivisé en deux parties: le CTE qui prenait en charge les cas de Covid -19 et le reste du service qui devait continuer à accueillir les patients atteints d'autres affections ou qui y étaient régulièrement suivies. (bvsalud.org)
  • In a multicenter, international study, we investigated if overweight, obesity, and diabetes were independently associated with COVID-19 severity and whether the BMI-associated risk was increased among those with diabetes.Research design and methodsWe retrospectively extracted data from health care records and regional databases of hospitalized adult patients with COVID-19 from 18 sites in 11 countries. (ox.ac.uk)
  • The medical records of CAP patients with definite etiology, such as viruses and bacteria, were retrospectively reviewed. (accjournal.org)
  • 3 The emergence of multi-drug resistant pneumococci has been an important reason for the development of new pneumococcal vaccines. (health.gov.au)
  • I spent nine years as the extramural program officer for the development and testing of bacterial vaccines, such as meningococcal, Hemophilus influenzae, pneumococcal, and pertussis vaccines. (nih.gov)
  • Pneumonia constituted the clinical diagnosis in 86 (68.8%) and 11 (78.6%) hospitalised children with MSMP and MRMP infections, respectively ( P =0.09). (annals.edu.sg)
  • According to statistics on the cause of death in Korea, even if deaths from pneumonia were only 9.4 per 100,000 population in 2007, they increased to 45.4 per 100,000 population in 2018, and pneumonia was the third most common cause of death in that report [ 2 , 3 ]. (accjournal.org)
  • Studies on the effects of viral coinfection on bacterial pneumonia are still scarce in South Korea. (accjournal.org)
  • 65 years (CURB-65), pneumonia severity index (PSI) and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores, while DHEA-S inversely correlated with the three scoring systems. (biomedcentral.com)
  • p less than 0.001), and this group also had more deaths due to pneumonia (p = 0.06). (nih.gov)
  • We prospectively collected outcome data on days 7 and 14, and retrospectively evaluated prescribing adherence with national clinical management guidelines.ResultsOf 433 children enrolled, the most common presenting syndromes were pneumonia and acute diarrhoea, diagnosed in 177 (40.9%) and 82 (18.9%), respectively. (tropmedres.ac)
  • Among children with pneumonia, independent predictors of persisting fever or death by 7 days were young age and underweight for age. (tropmedres.ac)
  • Pneumococcal disease was reported most frequently in children aged less than 5 years (47.3 cases per 100,000 population). (health.gov.au)
  • IPD presents most commonly as pneumonia in adults and bacteraemia in children. (health.gov.au)
  • Pneumococcal septicemia in children with sickle cell anemia: changing trend of survival. (cmcedmasters.com)
  • One of the main benefits of flu jabs for the elderly - protection against pneumonia - may not exist", BBC News reported. (zana.com)
  • Enhanced surveillance data revealed high rates of pneumococcal disease in Indigenous Australians. (health.gov.au)
  • It said that a study in thousands of vaccinated and unvaccinated people found that healthy, older people who had the jab had the same risk of pneumonia as those who had not. (zana.com)
  • Our study is unique in that we retrospectively evaluated transmission of TB to contacts exposed to index cases with less than three negative smear results. (cialis-database.com)