• The retinoblastoma protein (pRB) inhibits S-phase entry by repressing E2F ( 7 ). (pnas.org)
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)
  • A yeast two-hybrid screen was employed to identify human proteins that specifically bind the amino-terminal 400 amino acids of the retinoblastoma (Rb) protein. (asm.org)
  • Western blot analysis showed that stocks homozygous for two alleles, rbf2 M2 or rbf2 M3 , lack the full-length RBF2 protein and express a 30kD amino-terminal fragment of RBF2 (DRBF2). (sdbonline.org)
  • However, the mechanism by which senescence occurs is relatively unclear, though evidence suggests that the retinoblastoma protein (pRb), a potent tumor suppressor, may play a role ( 32 ). (asm.org)
  • Microbial infection) Interacts with molluscum contagiosum virus protein MC007. (rcsb.org)
  • However, the primary developmental impact of the loss of Rb protein has remained unclear. (le.ac.uk)
  • Lamin A/C binding protein LAP2 alpha is required for nuclear anchorage of retinoblastoma protein. (dur.ac.uk)
  • Markiewicz, E. and Dechat, T. and Foisner, R. and Quinlan, R. A. and Hutchison, C. J. (2002) 'Lamin A/C binding protein LAP2 alpha is required for nuclear anchorage of retinoblastoma protein. (dur.ac.uk)
  • We show that its pocket C domain is both necessary and sufficient for nuclear anchorage by transiently expressing green fluorescent protein (GFP) chimeras of Rb fragments in tissue culture cells and by extracting the cells with hypotonic solutions. (dur.ac.uk)
  • Rb is abruptly dephosphorylated at the end of mitosis probably by a type I protein phosphatase activated in anaphase ( 54 , 55 , 65 ). (asm.org)
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)