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  • Methods
  • As a consequence, these global-based methods suffer in handling details, such as recognizing the small thin vessels, discriminating the optic disk, etc. (bioportfolio.com)
  • The development of methods to measure retinal blood flow and blood oxygen saturation is crucial to improve understanding of the patho-physiology of major ocular diseases. (uwaterloo.ca)
  • The eye offers noninvasive direct access to the microvasculature and, through high-quality imaging and software-assisted grading methods, the retinal vessel may be evaluated with high reproducibility [ 6 , 7 ]. (hindawi.com)
  • superficial retinal
  • Among all parameters, statistically significant difference between no DR and mild NPDR was observed only in vessel tortuosity, especially within the 1.5 mm area of superficial retinal layer (P = 0.011). (ovid.com)
  • r = 0.268, P = 0.001 for FAZ acircularity), while vessel density strongly correlated with FAZ parameters in the superficial retinal layer and deep retinal layer. (ovid.com)
  • To evaluate the impact of image magnification correction on superficial retinal vessel density (SRVD) and foveal avascular zone area (FAZA) measurements using optical coherence tomography angiography (OCTA). (arvojournals.org)
  • angiography
  • Mice were subsequently anesthetized and imaged 15 minutes after IP injection with a Heidelberg Retinal Angiography confocal scanning laser ophthalmoscope, a 55° lens and a sensitivity set to 60. (arvojournals.org)
  • mean retinal
  • The mean retinal blood SO2 value at baseline in arterioles for 4 participants was 95.19% ± 31.04% and venules was 53.89% ± 17.24% (p = 0.115). (uwaterloo.ca)
  • In the 22 eyes of 18 patients in which CSME was diagnosed and treated, mean retinal vascular leakage at baseline was 5.6 (95% CI 4.2-7.6) nm/s, whereas eyes that did not progress to photocoagulation had a significantly lower mean leakage at baseline of 3.4 (95% CI 2.7-4.3) nm/s. (arvojournals.org)
  • diseases
  • The Relationship Between Retinal Vessel Oxygenation and Spatial Distribution of Retinal Nonperfusion in Retinal Vascular Diseases. (bioportfolio.com)
  • It is relevant to study the role of microvasculature in noncardiovascular mortality, because of the established link between small vessels and diseases such as diabetes mellitus, dementia, and chronic obstructive pulmonary disease [ 11 ]. (hindawi.com)
  • Static and dynamic retinal vessel analysis are promising tools for early risk evaluation of cardiovascular diseases. (arvojournals.org)
  • Because the vessel measurements have been shown to be predictive of cardiovascular and other systemic diseases, understanding the determinants of these familial relationships could have important health benefits. (arvojournals.org)
  • Segmentation of retinal blood vessels is significant to diagnosis and evaluation of ocular diseases like glaucoma and systemic diseases such as diabetes and hypertension. (hindawi.com)
  • 1 7 8 9 10 11 12 13 14 Information based on short-term experiments examining acute physiological responses are of limited value, however, in relation to the pathophysiology of the most prevalent retinal diseases, because most of these diseases are chronic. (arvojournals.org)
  • Glaucoma
  • To evaluate whether the position of the central retinal vessel trunk exit on the lamina cribrosa spatially correlates with the location of parapapillary atrophy in glaucoma. (mcmaster.ca)
  • After correction for normal values, the beta zone area of parapapillary atrophy in the glaucoma eyes was significantly larger, when measured in the disc quadrant most distant to the central retinal vessel trunk exit than as if measured in the quadrant containing the vessel trunk exit. (mcmaster.ca)
  • Position of the central retinal vessel trunk exit on the lamina cribrosa influences the location of parapapillary atrophy in glaucoma. (mcmaster.ca)
  • Retinal vessel caliber tends to be narrower in glaucoma patients than in healthy control subjects, and this tendency is more evident in advanced stages of the disease. (arvojournals.org)
  • Decreased ocular perfusion is hypothesized to contribute to retinal ganglion cell death in glaucoma. (arvojournals.org)
  • small vessels
  • The experiments implemented on the STARE database indicate that the new method has a better performance than the traditional ones on the small vessels extraction, average accuracy rate, and true and false positive rate. (hindawi.com)
  • relationship
  • There was a negative linear relationship between group retinal blood SO2 and TRBF values in the 10 participants studied, although the results of any of the 10 individuals did not show evidence of such a relationship using the described methodology. (uwaterloo.ca)
  • A relationship between retinal vessel characteristics and hypertension has been reported, 1 2 3 4 5 but until recently has been difficult to assess accurately. (arvojournals.org)
  • 9 11 12 Data from a number of studies have shown a relationship of hypertension to a narrowing of retinal arterioles. (arvojournals.org)
  • Stimulation
  • Wilcoxon rank-sum test was used to compare the mean values of retinal vessel dilation for flicker light stimulation and simultaneous flicker light stimulation and TES. (arvojournals.org)
  • The present study demonstrates that the retinal circulation reacts to electric stimulation at the SSN coordinates in rats. (arvojournals.org)