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  • Ophthalmology
  • From the Barnes Retina Institute and the Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri. (lww.com)
  • Additionally our eye doctors offer medical ophthalmology, diagnostic eye testing, glaucoma treatment, cornea disease surgery, eyelid surgery, ocular prosthesis, retina eye care, diabetes eye care, and state of the art no stitch cataract surgery. (sweye.com)
  • Retinas
  • Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors support a conceptually new model for retinal metabolism. (elifesciences.org)
  • choroid
  • The RPE is a monolayer of polarized cells between the choroid and retina that functions as a blood-retina barrier. (elifesciences.org)
  • Eyes were obtained from mPer2:Luc mice and the retina and choroid cup containing RPE were dissected in Hank's salt solution. (arvojournals.org)
  • The retina and RPE- choroid cup were carefully placed on the culture membrane (Millicell-CM pore size 0.4µm) in a 35 mm Petri dish with 1.2ml of 199 medium containing with 0.1mM D-Luciferin K salt, penicillin/streptomycin cocktail and B27. (arvojournals.org)
  • The bioluminescence emitted by the cultured retina and RPE-choroid was measured using a luminometer (Lumicycle, Actimetrics) for 10 days. (arvojournals.org)
  • Then, to test the effect of light on the circadian rhythm the retina and RPE-choroid explants were subjected to a pulse of light at different time of day. (arvojournals.org)
  • Both the retina and RPE-choroid explants showed robust circadian rhythms in the bioluminescence levels (mean free-running period 24.3±0.03 SEM and 23.7±0.02 SEM, respectively). (arvojournals.org)
  • Our data indicate that the retina and the RPE-choroid exhibited robust circadian rhythms, thus suggesting that the RPE contains an autonomous circadian clock. (arvojournals.org)
  • seep
  • the liquid portion of the vitreous is sometimes able to seep through the hole and peel the retina away from its blood supply in the wall of the eye. (sweye.com)
  • 1976
  • Burnside MB (1976) Possible roles of microtubules and actin filaments in retinal pigmented epithelium. (springer.com)
  • apical
  • If metabolic enzymes within the RPE cell do not consume it, the glucose moves down a concentration gradient toward the opposite side of the RPE cell where it exits to the retina through transporters on the apical surface of the RPE. (elifesciences.org)
  • vessel
  • In most of the ophthalmological image processing operations segmentation of retinal blood vessel is performed. (scribd.com)
  • in have presented an algorithm for vessel detection in retinal color images which works based on local Radon transform and morphological reconstruction. (scribd.com)
  • metabolism
  • The observation that RPE metabolism depends on mitochondria more than retina metabolism depends on mitochondria motivated us to compare directly the metabolic features of retina and RPE. (elifesciences.org)
  • nerve tissue
  • This disruption can quickly "starve" the retina (the vital nerve tissue) that records, transmits, or interprets visual images. (nih.gov)
  • disease
  • This framework for understanding metabolic relationships in the vertebrate retina provides new insights into the underlying causes of retinal disease and age-related vision loss. (elifesciences.org)
  • We identified functional tissue-specific enhancers in a genome-wide manner in the retina and RPE, including enhancers that regulate known visual disease genes such as ABCA4, USH2A and RPE65 . (arvojournals.org)
  • Examination of changes in the structure of retina is useful in understanding the stages of the disease process and their adverse effect on vision. (scribd.com)
  • To understand the disease stage of the retina, retinal images need to be processed using several image processing techniques. (scribd.com)
  • blood
  • An automated method of detection and extraction of blood vessels in retinal images composed of three steps matched filtering, fuzzy c-median (FCMED) clustering and label filtering is proposed [5, (scribd.com)
  • Siddalingaswamy and Prabhu in have proposed a hybrid method for efficient segmentation of multiple oriented blood vessels in colour retinal images. (scribd.com)
  • Without its normal attachment to the back of the eye, a detached retina loses part of its normal blood supply and loses the ability to function. (retinacarecenter.org)
  • Cells
  • The expression of the different inflammatory chemokine receptors in the retina and on retinal microglial cells (rMC) is unknown. (arvojournals.org)
  • Here we show that MSCs can differentiate into cells expressing markers of retinal cells, inhibit production of proinflammatory cytokines by retinal tissue and produce a number of growth and neuroprotective factors for retinal regeneration. (retina-international.org)
  • optic
  • On entering the eye, the optic nerve spreads out in a thin layer of nervous tissue-the retina-and covers the inside of the eye like wallpaper. (sweye.com)
  • causes
  • This causes the retina layer to detach, so it no longer works normally and causes vision loss in the affected area. (healthy-ojas.com)
  • function
  • Daily phagocytosis by the retinal pigmented epithelium (RPE) is essential for the function and viability of the photoreceptors. (arvojournals.org)
  • Futher phenotyping of these murine models could provide a better understanding of CLN-gene related retinal function and vascular structure. (egms.de)
  • patients
  • In addition, darkening of side vision is experienced in patients whose retina has detached from its original location. (tourmyindia.com)
  • Retinal oximetry was performed as part of the evaluation of these patients (Oxymap, Reykjavik, Iceland). (arvojournals.org)
  • 40 to 50 % of retinal detachment patients are nearsighted/shortsighted (myopic). (sightwise.org)
  • We have used the gold standard public database which contains retinal images of healthy patients, patients with diabetic retinopathy and glaucomatous patients. (scribd.com)
  • light
  • Retina - is a thin light sensitive tissue layer on the eye back. (healthy-ojas.com)
  • In the retina exposure to 10 minutes of light (1000 lux) during the subjective day or early night did not induce a phase-shift of the circadian rhythm whereas exposure to light in the late night induced significant phase-shifts (advance and delay). (arvojournals.org)
  • However light was able to phase-shift (i.e., synchronize) the circadian rhythm only in the retina. (arvojournals.org)