Loading...
  • neurons
  • The presence of receptors for ATP has not been established in any native preparation of retinal neurons or glia. (jneurosci.org)
  • Like the choroid plexus, the RPE plays an important glial-like role in maintaining the health and integrity of the nearby neurons, and the retinal-facing membrane contains an array of metabotropic receptors that enable the RPE to carry out its glial functions. (jneurosci.org)
  • This enrichment of CA XIV on specific membrane domains of glial cells and RPE suggests specialization for buffering pH and volume in retinal neurons and their surrounding extracellular spaces. (pnas.org)
  • apical
  • In the present study, we used conventional electrophysiological and [Ca 2+ ] in fluorescence imaging techniques to investigate the effects of ATP added to Ringer's solution perfusing the retinal-facing (apical) membrane of freshly isolated monolayers of bovine retinal pigment epithelium (RPE). (jneurosci.org)
  • cultures
  • Enzyme activities were measured both in paired fresh RPE isolates from the two retinal regions and in paired regional RPE cultures. (arvojournals.org)
  • vivo
  • To assess retinal toxicity in vivo , 200 mM of Nultin-3 or vehicle (DMSO) (n=12 rat eyes per condition) was injected once weekly for four weeks. (arvojournals.org)
  • Pax6
  • The transcription factors Pax2 and Pax6 are co-expressed in the entire optic vesicle (OV) prior and concomitant with the establishment of distinct neuroretinal, retinal, pigmented-epithelial and optic-stalk progenitor domains, suggesting redundant functions during retinal determination. (biologists.org)
  • Later, Pax6 expression becomes restricted to the lens, corneal and conjunctive epithelia, iris and inner portion of the NR ( Walther and Gruss, 1991 ). (biologists.org)
  • loss
  • Franco LM, Zulliger R, Wolf-Schnurrbusch UE, Katagiri Y, Kaplan HJ, Wolf S, Enzmann V (2009) Decreased visual function after patchy loss of retinal pigment epithelium induced by low-dose sodium iodate. (springer.com)