Retinal optic nerve. Medical search. Frequent questions

Glaucoma is a multifactorial neurodegenerative disease, characterized by degeneration of the retinal ganglion cells (RGCs). (elsevierpure.com)
Our interests are concentrated on early changes in the retina and the optic nerve during the course of glaucoma. (nih.gov)
Treatments currently available for glaucoma exert their effects by reducing IOP, the most important risk factor for the onset and progression of the disease, but have no direct effects on RGCs or the optic nerve and are not always optimally effective in slowing the progression of the disease. (nih.gov)
Thus, our study supports the idea that the σR1 is a promising therapeutic target for neurodegenerative retinal diseases, such as glaucoma. (molvis.org)
PURPOSE: To evaluate the parameters of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in patients with large cup/disc ratio (CDR) and normal neuroretinal rim configuration who have normal perimetry (physiologic large cups, LC) and to compare these parameters with those of the normal and early glaucoma patients. (elsevierpure.com)
METHODS: Using Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT), 30 patients with LC, 29 normal subjects, and 31 early glaucoma patients were examined. (elsevierpure.com)
Can Macula and Optic Nerve Head Parameters Detect Glaucoma Progression in Eyes with Advanced Circumpapillary Retinal Nerve Fiber Layer Damage? (nyu.edu)
Dive into the research topics of 'Can Macula and Optic Nerve Head Parameters Detect Glaucoma Progression in Eyes with Advanced Circumpapillary Retinal Nerve Fiber Layer Damage? (nyu.edu)
Hypertension, diabetes mellitus, atherosclerosis, and glaucoma are major risk factors for the development of central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) in older patients. (bmj.com)
Glaucoma Glaucomas are a group of eye disorders characterized by progressive optic nerve damage (often, but not always, associated with increased eye pressure) that can lead to irreversible loss of vision. (merckmanuals.com)
In late stages they may cause massive exudation and retinal detachment, uveitis (inflammation), glaucoma and phthisis (shrinking of the eye). (eyecancer.com)
Normal-tension glaucoma is a characteristic glaucomatous optic neuropathy with intraocular pressures in the normal range. (nih.gov)
Glaucoma is characteristic progressive optic neuropathy, featuring optic disc cupping and visual field loss, associated with raised intraocular pressure (IOP). (nih.gov)
Common retinal diseases such as age-related macular degeneration, glaucoma, and retinitis pigmentosa are covered, as are rare disorders such as Leber congenital amaurosis and Usher syndrome. (cshlpress.com)
Ruling out glaucoma in myopic eyes often poses a diagnostic challenge because of atypical optic disc morphology and visual field defects that can mimic glaucoma. (nih.gov)
We determined whether neuroretinal rim assessment based on Bruch's membrane opening (BMO), rather than conventional optic disc margin (DM)-based assessment or retinal nerve fiber layer (RNFL) thickness, yielded higher diagnostic accuracy in myopic patients with glaucoma. (nih.gov)
Myopic subjects with refraction error greater than -2 diopters (D) (spherical equivalent) and typical myopic optic disc morphology, with and without glaucoma, were recruited from a glaucoma clinic and a local optometry practice. (nih.gov)
The final classification of myopic glaucoma or myopic control was based on consensus assessment by 3 clinicians of visual fields and optic disc photographs. (nih.gov)
Bruch's membrane opening MRW is more sensitive than DM-RA and similar to RNFL thickness for the identification of glaucoma in myopic eyes and offers a valuable diagnostic tool for patients with glaucoma with myopic optic discs. (nih.gov)
M.D. Ophthalmology or Doctor of Medicine in Ophthalmology is a three year Post graduate course that is helpful in solving eye related problems like glaucoma, iritis, chemical burns orbital cellulite, eye trauma, crossed eyes, eye tumours, optic neuritis. (indiastudychannel.com)
These extracted markers or characterized fundus digital image features provide insights and relates quantitative retinal vascular topography abnormalities to various pathologies such as diabetic retinopathy, macular degeneration, hypertensive retinopathy, transient ischemic attack, neovascular glaucoma, and cardiovascular diseases. (hindawi.com)
Kitazawa Y, Shirato S, Yamamoto T: Optic disc hemorrhage in low-tension glaucoma. (karger.com)
Barry CJ, Cooper RL, Eikelboom RH: Optic disc hemorrhages and vascular abnormalities in a glaucoma population. (karger.com)
Hirota A, Mishima HK, Kiuchi Y: Incidence of retinal vein occlusion at the glaucoma clinic of Hiroshima University. (karger.com)
Recently, a novel neuroretinal rim parameter, based on the minimum rim width from Bruch's membrane opening to the neuroretinal surface (BMO-MRW), has demonstrated much greater effectiveness in evaluating the ONH for glaucoma than other optic disc margin measurements such as cup-to-disc ratio and rim area. (cdc.gov)
Diseases that damage the retina or optic nerve (such as glaucoma ) can lead to permanent blindness. (medlineplus.gov)

Cilioretinal Artery Occlusion Combined with Central Retinal Vein Occlusion: What Is the Best Imaging Modality for the Follow-Up? (hindawi.com)
A branch retinal artery occlusion (BRAO) occurs when one of these branches of the arterial supply to the retina becomes occluded. (medscape.com)
Color fundus photo of right eye with inferior branch retinal artery occlusion from a platelet-fibrin embolus. (medscape.com)
One study found that acute coronary syndrome occurred 1.72 times more often in patients with retinal artery occlusion than in controls. (medscape.com)
[ 16 ] Over a similar period, another study showed a 20% incidence of stroke in patients with retinal artery occlusion. (medscape.com)
Patients with branch retinal artery occlusion (BRAO) typically present with acute, unilateral, painless, partial visual loss. (medscape.com)
Retinal vein occlusion (RVO) is an interruption of the normal venous drainage from the retinal tissue. (bmj.com)
For an uncomplicated retinal vein occlusion, whether it is ischemic or nonischemic, management consists of close monitoring to detect complications and treatment of underlying risk factors. (bmj.com)
Characteristically, in the retina proximal to the occlusion, the affected venous system is tortuous and dilated, and there are several intraretinal hemorrhages and retinal edema. (bmj.com)
Once retinal artery occlusion has been diagnosed, doctors need to search for a source of an embolus. (msdmanuals.com)
AMD), occlusion of retinal vessels (ORV), etc. (who.int)

Hence, our findings indicate that the antiaging α-klotho plays a protective role against EMT and degeneration of the RPE, demonstrating the therapeutic potential for age-related retinal diseases, including the dry type of AMD. (opticnervenetwork.com)
Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders that often lead to photoreceptor degeneration. (nature.com)
To treat retinal degenerative diseases, a transcorneal electrical stimulation-based system is proposed, which consists of an eye implant and an external component. (mdpi.com)
A woman in Kenya undergoes retinal imaging to screen for optic nerve diseases. (weforum.org)
Choroidal and retinal neovascularization plays an essential role in various ocular diseases. (molvis.org)
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews recent work on retinal diseases, describing their genetic and molecular basis, their clinical characteristics, and strategies to diagnose and treat them. (cshlpress.com)
In particular, the authors describe impressive advances in gene therapy treatments for retinal diseases, some of which have led to clinical success. (cshlpress.com)
Retinal microvascular abnormalities like microaneurysm, arteriovenous nicking, haemorrhages, and vessel caliber are considered as associative to the stroke and indicative of death from stroke and IHD (Ischemic Heart Diseases) [ 1 ]. (hindawi.com)
Implementation of a registry and open access genetic testing program for inherited retinal diseases within a non-profit foundation. (cdc.gov)

Optic nerve section in the newborn rat results in a rapid apoptotic degeneration of most axotomized retinal ganglion cells (RGCs). (nih.gov)
We profiled the retina transcriptome of Lister Hooded rats at 2 weeks after optic nerve crush (ONC) and analyzed the data from the genomic fabric paradigm (GFP) to bring additional insights into the molecular mechanisms of the retinal remodeling after induction of RGC degeneration. (elsevierpure.com)
This deep bioinformatic study provided novel insights beyond the regulation of individual gene expression and disclosed changes in the control of expression of complement cascade and Notch signaling functional pathways that may be relevant for both RGC degeneration and remodeling of the retinal tissue after ONC. (elsevierpure.com)
Here, we used the σR1-knockout mouse ( Sigmar1 −/− ) to demonstrate unambiguously the role of the σR1 in protecting the retinal ganglion cells against degeneration after acute damage to the optic nerve. (molvis.org)
Our data indicated faster retinal ganglion cell death in Sigmar1 −/− than in wild-type mice under the stresses caused by optic nerve crush, providing direct evidence for a role of the σR1 in alleviating retinal degeneration. (molvis.org)
Individuals with this condition usually start showing signs of nyctalopia (also known as night-blindness) during their early childhood, increase in sensitivity to blue light, progressive decrease of visual acuity in both eyes, cataract, peripheral vision loss, vitreous liquefaction and detachment, clumped pigment deposits of the fundus, either peripheral or central retinoschisis, cystic macular edema, and retinal degeneration. (wikipedia.org)
cataract, retinal degeneration, and nightblindness. (wikipedia.org)
Degenerative changes of the retinal pigment epithelium (RPE) triggered by transforming growth factor-β2 (TGF-β2) and oxidative stress play a critical role in the progression of age-related macular degeneration (AMD). (opticnervenetwork.com)
Biallelic variants in the cilia gene DYNC2H1 have been associated with two severe ciliopathies: Jeune asphyxiating thoracic dystrophy (JATD, MIM 613091) and short-rib polydactyly (SRP, MIM 613091) with only four documented cases of associated complex early retinal degeneration at ages 2 months, and 2, 5, and 11 years old. (nature.com)
Wallerian degeneration includes a characteristic demyelinating response of Schwann cells surrounding the distal stump of an injured peripheral nerve. (jneurosci.org)
Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A). (cdc.gov)

Given that the eye possesses clear optics and shares many neural and vascular similarities to the brain, it offers a direct window to cerebral pathology. (frontiersin.org)
Retinal vascular development begins at 15 to 18 weeks gestation. (medscape.com)
Therefore, anything that interferes with the maturation of retinal vascular development puts the infant at increased risk of developing ROP. (medscape.com)
Retinal capillary hemangiomas are usually orange red, circumscribed, round, vascular tumors supplied by a pair of dilated and tortuous feeder vessels. (eyecancer.com)
Proposed IOP-independent mechanisms include vascular insufficiency at the optic nerve head, metabolic and neurodegenerative disorders, oxidative stress, and abnormal biomechanics of the lamina cribrosa. (nih.gov)
Some distinct changes in the retinal microvasculature are recognized as the preindicator of subsequent vascular incidents like ischemic stroke or acute stroke [ 10 ]. (hindawi.com)
The patient displayed a pathologic phenomenon that was associated sickle cell disease (SCD), and included posterior retinal and macular vascular occlusions. (cdc.gov)

Four MS patients had a history of bilateral optic neuritis (ON), four had a history of unilateral ON, and 4 had no history of ON. (elsevierpure.com)
In optic neuritis (ON), transient thickening of the macular retinal nerve fibre layer (RNFL) can be observed. (lu.se)
Typical symptoms of relapses may be referable to demyelinating pathology involving the optic nerves (e.g. optic neuritis), brainstem (e.g. internuclear ophthalmoplegia) or spinal cord (e.g. partial myelitis), although non-specific symptoms referable to the cerebral hemispheres or other brain regions can also occur (Katz Sand and Lublin, 2013). (medscape.com)

There is a whitening on the temporal edge of the optic nerve consistent with an optic disc pit and there is a serous macular detachment. (retinagallery.com)
The sequence associated with plus disease almost always precedes partial or complete retinal detachment. (medscape.com)
Glial proliferation can lead to tractional retinal detachment and macular pucker. (eyecancer.com)
I had a vitrectomy and scleral buckle 1 year ago to repair a retinal detachment. (medhelp.org)

Ping Ji decided to measure and catalogue these differences by taking fundus photographs in children with Down's syndrome and typical children, and analyse the size and shape of the optic disc and the numbers and arrangement of blood vessels. (cardiff.ac.uk)
As observed on angiography, the numbers of choroidal and retinal blood vessels were significantly increased (principally on the seventh day) after the laser impacts. (molvis.org)
Blockage of the central retinal vein may also cause growth of abnormal blood vessels on the retina or iris. (merckmanuals.com)
Furthermore, image analysis provides a simple and noninvasive visualization of the retinal blood vessels in those high risk ophthalmologic medical conditions [ 1 - 3 ]. (hindawi.com)
an inflammation of the blood vessels, is also a possible cause of retinal artery blockage. (msdmanuals.com)

[ 15 ] A10-fold increase in the annual rate of stroke in patients with retinal emboli compared with controls after a follow-up period of 3.4 years was demonstrated in another study. (medscape.com)
A case series reported that 15% of patients with retinal emboli died within 1 year, and a mortality rate of 54% was shown within 7 years. (medscape.com)
In a study of 70 patients with retinal emboli, 40 were found to have cholesterol emboli, 8 platelet-fibrin emboli, 6 calcific emboli, and 1 possible myxomatous embolus. (medscape.com)

Design, Setting, and Participants: In the National Aeronautics and Space Administration's "Fluid Shifts Study," a prospective cohort study, optical coherence tomography scans of the optic nerve head and macula were obtained from US and international crew members before flight, in-flight, and up to 180 days after return to Earth. (henryford.com)
Macula, retinal vessels, and periphery appeared normal in both eyes. (aao.org)
The fundus retinal images are directly captured from human eye that includes some other landmarks like microcirculation system of the retina, macula, optic disc, fovea, microaneurysm, and exudates [ 4 ]. (hindawi.com)

In 90% of cases, BRAOs involve the temporal retinal vessels. (medscape.com)
Whether the temporal retinal vessels are affected more often or whether the nasal retinal vessel occlusions are more often undetected is unclear. (medscape.com)
Undifferentiated endothelial cells are critical to the development of retinal vessels. (medscape.com)
[ 7 ] Retinal endothelial cells give rise to primitive capillaries that further differentiate into mature vessels. (medscape.com)
Exposure to stressors damages developing retinal vessels and temporarily arrests their development. (medscape.com)
Occasionally, the eye becomes inflamed and hazy and exudates form along the retinal vessels with engorgement and tortuosity of the posterior pole vessels. (medscape.com)
CNS manifestations include vasculitis of small to medium-sized vessels of the brain or spinal cord and granulomatous masses that involve the orbit, optic nerve, meninges, or brain. (medscape.com)
Note that the retinal vessels appeared to be emanating from below, within a circular, lighter area known as the optic disc. (cdc.gov)
Also note, the presence of fibrous deposition within the retinal tissues adjacent to these occluded vessels, as well as the tortuosity of the retinal arterioles. (cdc.gov)

To evaluate differences in macular and optic disc circulation in patients affected by Wolfram Syndrome (WS) employing optical coherence tomography-angiography (OCTA) imaging. (opticnervenetwork.com)

RESULTS: Significant differences between LC and glaucomatous eyes (GE) were found in parameters indicating loss of nerve fibers, such as rim area, rim volume, and mean RNFL thickness. (elsevierpure.com)
Background: Measurement of retinal nerve fiber layer (RNFL) thickness in multiple sclerosis (MS) is gaining increasing attention. (elsevierpure.com)
Objectives: To explore the relationship between RNFL thickness as measured by optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx), and conventional and non-conventional optic nerve and brain MRI measures. (elsevierpure.com)
Results: LCLA, RNFL-OCT and optic nerve radius measures showed more robust differences between NC and MS patients, and between MS patients with affected and unaffected eyes. (elsevierpure.com)
Unique additive variance regression models showed that both brain and optic nerve MRI measures independently accounted for about 50% of the variance in LCLA and RNFL thickness. (elsevierpure.com)
Conclusions: Measurement of RNFL thickness and radius of the optic nerve should be preferred to the other optic nerve MRI measures in clinical studies. (elsevierpure.com)
The data suggest that up-regulation of Nf expression in the retinal ganglion cells precedes development of RNFL atrophy and plausibly explains the transient increase of axonal diameter and RNFL thickening. (lu.se)
Racial differences in the anatomy of the optic nerve head (ONH), such as larger optic discs and disc area, deeper cups, variation in lamina cribrosa position, and thicker overall retinal nerve fiber layer (RNFL) and peripapillary choroid thicknesses in AD individuals, have also been previously described. (cdc.gov)
The purpose of this study is to determine if BMO-MRW varies with race, specifically across people of AD and ED, and how BMO-MRW relates to retinal nerve fiber layer (RNFL) thickness. (cdc.gov)

They demonstrated their critical involvement in a rat model of retinal and choroidal neovascularization experimentally induced using ocular laser impacts. (molvis.org)

It is a group of optic neuropathies characterized by the death of retinal ganglion cells (RGCs), leading to a specific deformation of the optic nerve head. (nih.gov)
Retinal ganglion cells (RGCs) develop in waves, starting at the central retina and then progressing outward toward the periphery. (jneurosci.org)

Occasional findings include optic nerve atrophy. (wikipedia.org)
Optic nerve MRI measurements included the length of T2 lesions, measurement of optic nerve atrophy, magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI) measures. (elsevierpure.com)
Optic nerve atrophy was measured by a novel method with high reproducibility. (elsevierpure.com)

We used Brown Norway rats, in which choroidal and retinal neovascularization was induced using intraocular laser impacts. (molvis.org)

The central retinal artery, a branch of the ophthalmic artery, enters the eye through the optic disc and divides into multiple branches to perfuse the inner layers of the retina. (medscape.com)
The main ophthalmic finding in VHL is retinal capillary hemangioma, which is a benign hamartoma. (eyecancer.com)

Once the retinal vein blockage has been diagnosed, doctors often do tests to identify disorders that could increase the risk of developing blockages. (merckmanuals.com)
Hereditary, physiologic, or environmental factors can lead to various retinal disorders and may cause blindness. (cshlpress.com)
The recent application of molecular genetic techniques to retinal disorders has led to remarkable advances in the understanding, diagnosis, and treatment of these conditions. (cshlpress.com)

The fundus findings of retinal capillary hemangioma are usually typical, and diagnosis can be made based on ophthalmoscopic examination. (eyecancer.com)
One of the most important subfields of biomedical engineering is the analysis of fundus retinal images. (hindawi.com)
Analysis of the human fundus eye images has become the key point for diagnosing the various pathologies of retinal vasculature. (hindawi.com)

Optic nerve glioma appears on a computed tomography (CT) scan or magnetic resonance image (MRI) as a fusiform dilatation of the optic nerve. (medscape.com)

[ 7 ] Retinal vessel development begins at the optic nerve and progresses into the periphery. (medscape.com)
Central retinal explants from embryonic day 5 (E5) chicks, but not periphery explants, promoted RGC axon growth from adjacent "test" explants. (jneurosci.org)

Quantification of cells remaining after optic nerve crush showed that 86.8±7.9% cells remained in the wild-type ganglion cell layer, but only 68.3±3.4% survived in the Sigmar1 −/− , demonstrating a significant difference between the wild-type and the Sigmar1 −/− in crush-induced ganglion cell loss. (molvis.org)
Whereas IOP is the main driver of progressive visual loss in most patients with POAG, NTG likely represents a heterogeneous or multifactorial group of etiologies, with a common final pathway of retinal ganglion cell loss. (nih.gov)

Optic nerve head topographic measurements and retinal nerve fiber layer thickness in physiologic large cups. (elsevierpure.com)
Main Outcomes and Measures: Changes in minimum rim width, optic cup volume, Bruch membrane opening height, peripapillary total retinal thickness, and macular thickness. (henryford.com)

Optic nerve injury also induced Ki67+ cells in the optic nerve but not in the retina. (umn.edu)
The eye's retina is made up of photoreceptor (light-sensitive) cells and nerve cells in the optic nerve (which connects the eye to the brain). (medlineplus.gov)

Purpose: To determine the frequency with which retinal tissues other than the nerve fibre layer, hereafter referred to as protruded retinal layers (PRL), are a component of optical coherence tomography (OCT) neuroretinal rim measurements. (elsevierpure.com)
Surviving cells in the ganglion cell layer were counted on Nissl-stained retinal whole mounts 7 days after the crush surgery. (molvis.org)
Purpose: To evaluate the ability of OCT optic nerve head (ONH) and macular parameters to detect disease progression in eyes with advanced structural glaucomatous damage of the circumpapillary retinal nerve fiber layer (cRNFL). (nyu.edu)

The differential diagnosis included an optic neuropathy versus retinopathy. (aao.org)
With that in mind, we now included central serous retinopathy, retinal migraine, acute macular neuroretinopathy, and unilateral acute idiopathic maculopathy in our differential diagnosis. (aao.org)
The diagnosis of retinal hemorrhage was made by an ophthalmologist after dilated fundoscopic examination. (cdc.gov)
The mean age at diagnosis of retinal capillary hemangioma in VHL disease is approximately 25 years, and most patients present between the ages of 10 and 40 years. (eyecancer.com)
The diagnosis might be confused with retinal macroaneurysm or adult Coats disease when severe exudation exists. (eyecancer.com)

Retinal tissue Nf concentrations per total protein (μg/mg) were significantly higher in MOG-EAE rats with ON (median 4.29, interquartile range [IQR] 3.41-5.97) compared with MOG-EAE rats without ON (1.14, IQR 1.10-1.67) or control rats (0.93, IQR 0.45-4.00). (lu.se)

From an ocular standpoint, and in the absence of subsequent retinal artery occlusions, vision usually stabilizes soon after the ischemic event. (medscape.com)
Rotterdam cohort study also came into a decision after a long-term observation that the retinal venular diameter is associated with any stroke or ischemic stroke [ 14 ]. (hindawi.com)

Retinal ganglion cell death was induced by acute optic nerve crush in wild-type and Sigmar1 −/− mice. (molvis.org)
Acute exposure to 25-mm Hg lower-body negative pressure did not alter optic nerve head or retinal morphology, suggesting that longer durations of a fluid shift reversal may be needed to mitigate spaceflight-induced changes and/or other factors are involved. (henryford.com)
According to the study of [ 12 ] with a multiethnic cohort, retinal arteriolar narrowing and retinopathy of diabetic free people have an association with increased risk of acute stroke. (hindawi.com)

Strengthens nerve impulses and positively affects the functional state of the nervous tissue of the visual center. (kalinka-store.com)
The axonal diameter correlates with the neurofilament (Nf) protein content, but there are no data on the retinal tissue concentration of Nfs. (lu.se)
Retinal tissue Nf concentrations per total protein. (lu.se)
But when a zebrafish's retina is damaged, certain cells trigger the affected tissue to regrow and restore vision, a process called "retinal regeneration. (medlineplus.gov)

Various diagnostic techniques are used to analyze retinal microvasculature image to enable geometric features measurements such as vessel tortuosity, branching angles, branching coefficient, vessel diameter, and fractal dimension. (hindawi.com)

Gene therapy for inherited retinal and optic nerve degenerations. (cdc.gov)

Retinal and optic nerve complications in a high dose irradiat. (iaea.org)

We report 4 patients with retinal hemorrhages that developed during hospitalization for de ngue fever. (cdc.gov)
Retinal hemorrhages may reflect the rising incidence of dengue in Singapore or may be caused by changes in the predominant serotype of the dengue virus. (cdc.gov)
Rarely, retinal hemorrhages affecting patients with dengue fever are reported. (cdc.gov)
We report 4 patients with dengue fever complicated by retinal hemorrhages who were hospitalized in our institution in June and July 2004. (cdc.gov)
In the same period, retinal hemorrhages were diagnosed in 4 dengue fever patients in our hospital. (cdc.gov)
Retinal or vitreal hemorrhages are rarely observed, occurring in fewer than 3% of cases. (eyecancer.com)

Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons. (umn.edu)

Forty-five children with Down's syndrome and 44 typical children took part.The analysis isn't fully completed yet, but Ping has found, quite unexpectedly, that children with Down's syndrome have larger optic discs. (cardiff.ac.uk)

Here we evaluated the use of high-resolution 7 T structural T1-weighted magnetic resonance imaging (MRI) and 9.4 T diffusion tensor imaging (DTI) for detecting hippocampal fNCSE-induced retinal pathology ex vivo in mice. (lu.se)
We conclude that retinal pathology after fNCSE in mice is subtle and present bilaterally. (lu.se)

Bilateral optic nerve gliomas are almost pathognomonic for NF-1. (medscape.com)
Retinal capillary hemangioma usually manifests as a solitary tumor, but approximately one-third of patients have multiple retinal hemangiomas, and up to half of patients have bilateral involvement. (eyecancer.com)

Retinal vein occlusions are usually painless, sudden, and unilateral causes of vision loss. (bmj.com)

Narrowed branch retinal artery, boxcarring, segmentation of the blood columns, cotton-wool spots, and emboli are other possible findings. (medscape.com)

Conclusions: Protruded retinal layers are a component of MRW measurements in most normal subjects, occurring in almost 12% of all measurement points analysed. (elsevierpure.com)

[ 12 ] Retinal vessel development resumes at 30 to 34 weeks' gestation. (medscape.com)
The central retinal artery is the main vessel that supplies blood to the retina. (msdmanuals.com)

Is the Subject Area "Optic disc" applicable to this article? (plos.org)
They more likely are found in the larger arterioles near the optic disc. (medscape.com)
Because children with Down's syndrome have slightly poorer vision than typical children, we expected to find that the optic disc is smaller in Down's syndrome. (cardiff.ac.uk)
birth defects: coloboma of choroid or optic nerve disc, etc. (who.int)

Secondary effects (from the retinal angioma) leading to visual loss, such as intraretinal and subretinal exudation, are often limited to the vicinity of the hemangioma but can be remote, often producing a macular star of exudates. (eyecancer.com)

This was the point where the retinal arterioles, and optic nerve, entered the rear of the eyeball. (cdc.gov)

Blockage of the central retinal vein causes severe, painless, and usually sudden loss of vision, but vision loss can also sometimes occur gradually over a period of days to weeks. (merckmanuals.com)

Changes in Optic Nerve Head and Retinal Morphology During Spaceflight " by Laura P. Pardon, Brandon R. Macias et al. (henryford.com)

NTG can masquerade as other optic neuropathies, and care should be taken to adequately investigate other causes when indicated. (nih.gov)

An estimated 15-40% of children with NF-1 have optic nerve glioma or visual pathway gliomas involving the optic nerve, chiasm, or optic tract. (medscape.com)

Anatomy71

Organisms9

Diseases50

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Psychiatry and Psychology4

Phenomena and Processes16

Disciplines and Occupations3

Technology, Industry, Agriculture1

Glaucoma26

Occlusion11

Diseases9

Degeneration11

Vascular7

Neuritis3

Detachment4

Blood vessels5

Patients with retinal emboli3

Macula3

Vessels9

Optical coherence tomography a1

RNFL9

Model of retinal1

RGCs2

Atrophy3

Choroidal1

Ophthalmic2

Disorders3

Fundus3

Computed tomography1

Periphery2

Ganglion cell loss2

Thickness2

Cells in the optic nerve2

Layer3

Diagnosis5

Rats1

Ischemic2

Acute3

Tissue4

Tortuosity1

Degenerations1

Complications1

Hemorrhages6

Crush1

Larger optic discs1

Pathology2

Bilateral2

Unilateral1

Branch1

Measurements1

Vessel2

Disc4

Exudates1

Arterioles1

Painless1

Morphology1

Neuropathies1

Visual pathway1