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  • neovascular
  • We counted the number of neovascular nuclei extending into the vitreous cavity and prepared whole-mount retinas perfused with high-molecular-weight rhodamine-conjugated dextrans to visualize retinal vessels. (arvojournals.org)
  • The systemic administration of a M-CSF inhibitor depletes retinal macrophages and prevents MacTel-like outer retinal neovascular tuft formation in the VLDLR -/- mouse, an animal model resembling MacTel. (arvojournals.org)
  • At year 1, there was a decrease in the total area of neovascularization in groups A and B, and an increase in group C. Adverse events included a vitreous hemorrhage in 1 patients in group A, 3 patients in group B and 2 patients in group C. One patient in group B developed neovascular glaucoma. (arvojournals.org)
  • flat mounts
  • Retro-orbital injection of FITC-dextran was performed and retinal flat mounts were viewed by fluorescence microscopy and photographed. (arvojournals.org)
  • After enucleation, eyecups without cornea, lens and vitreous were fixed in 4% paraformaldehyde (PFA) for one hour on ice, and Isolectin B4 stained retinal flat mounts were prepared. (utah.edu)
  • Pups were moved to room air at p14 and euthanized at p18 or p25 for analyses of mRNA, protein, retinal flat mounts and immunohistochemistry. (arvojournals.org)
  • Microscopic analysis of retinal flat mounts and cross-sectional samples confirmed the changes observed in in vivo structural and functional OCT images. (arvojournals.org)
  • hemorrhage
  • The new vessels formed in these processes are prone to hemorrhage and are hyperpermeable, leading to retinal edema, as well as lipid and protein exudation. (arvojournals.org)