• stage II-basal) with a coefficient of reproducibility (CR) of 22%, 21% and 25%, respectively. (bmj.com)
  • It shows that the cavity gives very good character in terms of high quality factor, relaxed tuning range, adequate coupling coefficient, and reasonable reproducibility. (cern.ch)
  • Levels of concurrent validity and reproducibility were expressed with intraclass correlation coefficients (ICC) and coefficient of variation (CV), while agreement was expressed by standard errors of measurement (SEM). (minervamedica.it)
  • 3. Our results suggest that the mean and the coefficient of skew fully described a night's S a o 2 . (portlandpress.com)
  • The experimental results show the good sensitivity and reproducibility of XANES to characterize the local geometry and electronic environment of the sulfur K -shell under various conditions of vulcanization and non-vulcanization of natural rubber. (iucr.org)
  • The study shows how the Mastermind Genomic Search Engine benefits clinical diagnostic laboratories by significantly improving the sensitivity and reproducibility of clinical variant interpretation. (prweb.com)
  • The surfaces were scored based on biocompatibility and probe binding capacity as judged by spot morphology, signal intensities, signal to noise ratios, dynamic range, sensitivity, and reproducibility. (lu.se)
  • The aims of the study were to assess the reproducibility and validity of very weak knee flexors and extensors muscle strength with a new isokinetic evaluation procedure. (iospress.com)
  • Objective: To assess the reproducibility of two diet assessment methods, an extensive quantitative food frequency questionnaire (method A) and a novel shorter quantitative food frequency questionnaire with a 14 day food record (method B). Design: A randomized prospective cohort study. (lu.se)
  • This small prospective study from a single center showed that the renal cortex's color Doppler sonographic dynamic tissue perfusion measurement had very good intraobserver reproducibility. (medscimonit.com)
  • The published literature on V/Q SPECT has consistently shown improvements in sensitivity ( 2 , 3 ), specificity ( 3 , 4 ), and intraobserver reproducibility ( 2 - 4 ), as well as reducing the number of intermediate or inconclusive results to less than 5% ( 3 , 5 ). (snmjournals.org)
  • With respect to the definition of endpoints, several of the commonly used UESTD physical examination maneuvers have been shown to lack high sensitivity and specificity. (cdc.gov)
  • We posit that a contributor is simply a lack of specificity that is required to enable adequate research reproducibility. (researchgate.net)
  • Taken together, the results shown in the study demonstrate the utility and superiority of Mastermind in terms of both sensitivity and specificity of automated results for clinical diagnostic variant interpretation for multiple genetic variant types, and highlight the potential benefit in informing pharmaceutical research. (prweb.com)
  • Studies have shown that ultrasound can demonstrate the hallmarks of inflammatory arthropathy with good sensitivity and specificity, said Dr. Philip O'Connor, also a musculoskeletal radiologist at the Leeds Teaching Hospitals. (diagnosticimaging.com)
  • CT has been shown to have slightly higher sensitivity, and ultrasonography to have higher specificity for diagnosis of AAA. (medscape.com)
  • RESULTS: The overall cutoff concentration for the classification of cigarette smokers from nonsmokers was 7.32ng/mL with high sensitivity and specificity (0.925). (cdc.gov)
  • In conclution, DNA amplification is a rapid, reliable and accurate method with a high degree of sensitivity and specificity for the detection of Mycobacterium tuberculosis DNA sequences and it can replace the conventional culture method in the diagnosis of extra pulmonary tuberculosis and tuberculosis meningitis except in the situation when antibiotic sensitivity results are required. (who.int)
  • That's fitting, since our inability to independently replicate our results, I argue, threatens to undermine trust in the scientific enterprise-something every citizen has a stake in. (nautil.us)
  • The Brazilian Reproducibility Initiative , which aims to replicate between 60 and a 100 experiments from Brazilian biomedical science using common laboratory methods, provides a unique opportunity to study this question. (bmj.com)
  • Results showed good reproducibility between two replicate mesocosms. (ku.dk)
  • Analytical sensitivity, repeatability, and reproducibility were also determined. (scienceopen.com)
  • The repeatability and reproducibility were excellent. (scienceopen.com)
  • The method showed good selectivity, repeatability, accuracy and sensitivity. (who.int)
  • The study demonstrates that RER-based estimates of AT correlate well with the blood lactate-based AT determination. (jssm.org)
  • Furthermore, the PIOPED 2 study demonstrated that the CTPA accuracy deteriorates further if the scan results do not correlate with the clinical likelihood of disease, and in these circumstances, the incidence of false-positive and false-negative results is significant ( 6 ). (snmjournals.org)
  • These include indicators of methodological rigor such as randomisation and blinding, which are widely thought to reduce risk of bias , as well as effect sizes and statistical results - which have been shown to correlate with reproducibility in psychology studies . (bmj.com)
  • The purpose of this study was to evaluate the validity of CAVI compared with baPWV, the reproducibility of the measurement of CAVI, and the effect of BP changes on CAVI and baPWV. (go.jp)
  • Isokinetics and Exercise Science publishes studies associated with the methodology of muscle performance especially with respect to the issues of reproducibility and validity of testing, description of normal and pathological mechanical parameters which are derivable from muscle testing, applications in basic research topics such as motor learning paradigms and electromyography. (iospress.com)
  • METHODS: Ten male runners participated in the experimental protocol for an analysis of the reproducibility, and 20 other runners participated in the experimental protocol for the analysis of the validity of the device. (minervamedica.it)
  • Can we predict the reproducibility of biomedical studies? (bmj.com)
  • In spite of high reliability and reproducibility, … this method does not allow the investigation of the dynamic properties of muscle. (iospress.com)
  • Although this feature is well established, sufficient observer reliability and diagnostic accuracy are prerequisites for advancements of this method. (bmj.com)
  • The elucidation of mechanical behavior utilizing industry practices can contribute to their resolution as well as medical reliability and safety. (hindawi.com)
  • 2. Main strengths: Please describe the main strengths of the work, considering primarily the following axes: originality/novelty, significance/impact, soundness/technical quality, reproducibility and clarity of writing. (ucsd.edu)
  • When curated for clinical significance, Mastermind identified more than 4.9-fold more pathogenic genetic variants than ClinVar for representative genes and demonstrated a 4.0- to 43.9-fold increase in references for specific Copy Number Variations (CNVs) compared to PubMed, as well as 5.4-fold more fusion genes when compared with COSMIC's curated database. (prweb.com)
  • Although there is no doubt that referring clinicians would like a diagnostic imaging test for PE that is highly sensitive and specific for disease detection, as well as being perfectly safe, it is apparent from the PIOPED 2 study that CTPA does not meet these criteria. (snmjournals.org)
  • RESULTS: A visual representation of the total testing process was developed and contextualized to patient care scenarios using a number of examples covering the detection of blood culture contamination, use of next-generation sequencing, and pharmacogenetic testing. (cdc.gov)
  • They found incomplete coverage of genes associated with Mendelian disorders, low reproducibility of detection of genetic variation, as well as uncertainty about clinically reportable findings. (cdc.gov)
  • They show that many of the genes recently identified by the American College of Medical Genetics as having potentially high clinical impact were not covered sufficiently to achieve clinical variant detection without further confirmation. (cdc.gov)
  • These findings point to the necessity of more stringent monitoring of mycotoxins, particularly AFB1 in maize, as well as the value of regular assessment using LC-MS/MS. (frontiersin.org)
  • Quality assessment exercises were conducted to evaluate the reproducibility of IS 6110 DNA fingerprinting performed by eight laboratories in the National Tuberculosis Genotyping and Surveillance Network. (cdc.gov)
  • To test the proficiency of laboratories and determine the reproducibility of this genotyping technique in a large network of laboratories, the Centers for Disease Control and Prevention (CDC) instituted quality assessment exercises for the seven genotyping network laboratories. (cdc.gov)
  • Thus, for the first time, experimental results were obtained on the effect of irradiation on carbon-doped porous silicon obtained in a solution containing hydrogen hexafluorosilicate H 2 (SiF 6 ) and a significant change in its optical properties was shown. (hindawi.com)
  • Credits can later be redeemed as Amazon gift cards according to prediction success once experimental results are in. (bmj.com)
  • CAVI showed a weaker correlation with SBP than baPWV. (go.jp)
  • Method B showed a good agreement between measurements for energy-providing nutrients, micronutrients and major food groups, i.e. meat products, edible fats, milk, fish, fruits and vegetables with correlation coefficients between 0.70-0.90 for women. (lu.se)
  • Analysis of clinical samples showed a good correlation between the INT-O and LTR-O assays (r = 0.8240), with an improvement of analytical sensitivity. (scienceopen.com)
  • A good correlation was also obtained between the INT-O and Abbott assays (r = 0.8599) but with significantly higher values (0.19 logs) for the INT-O method, due to marked underquantifications for some patients. (scienceopen.com)
  • Nevertheless, these results are unable to explain the lack of De correlation with K. Finally, we investigate the dependence of D e on grain size (isochrons). (dtu.dk)
  • The study of the correlation between prognosis and Gender, and prognosis and rehabilitation hospital for surgery was done only with the rates determined by the researcher, which were grouped into good regular and poor prognosis. (bvsalud.org)
  • Reproducibility among examiners has not been well studied. (cdc.gov)
  • Bland-Altman plots showed an even distribution of data for RER-AT, while a more scattered and skewed distribution of data was observed when EqO 2 -AT and Vslope-AT were compared with Lactate-AT. (jssm.org)
  • Implications for rehabilitation Measurement of quality of life during rehabilitation can provide important information on patients' well-being. (nih.gov)
  • The measurement of CAVI demonstrated good reproducibility and was not affected by the increase in BP during measurement. (go.jp)
  • The measurement results of this brazed cavity are described and summarized in this report. (cern.ch)
  • This method is the one most commonly used for pH measurement, since the potential quickly reaches equilibrium and shows good reproducibility, and because the method can be used on various types of solutions, with oxidizing or reducing substances having very little impact on the result. (horiba.com)
  • This is a measurement method in which pH is determined at multiple points and the results displayed as an image. (horiba.com)
  • 5. Measurements made on two occasions in seven subjects showed good reproducibility for the skew and M 3 100 indices. (portlandpress.com)
  • Micro-XRF is shown to be sufficiently precise and accurate and luminescence instrument reproducibility is confirmed using dose recovery measurements on heated feldspar. (dtu.dk)
  • Overall, SWATH-MS measurements showed a slightly lower sensitivity and a comparable reproducibility to state-of-the-art SRM measurements for targeted quantification of the N-glycosites in human blood. (nih.gov)
  • Methods and Results One thousand and thirty-three consecutive subjects undergoing health checkups were studied. (go.jp)
  • Subjects and methods: Reproducibility mean and maximal work without correction of gravity was first assessed in 14 neuromuscular patients, at 10°/s. (iospress.com)
  • Anaerobic threshold can reliably be estimated by respiratory gas indices in well fit subjects. (jssm.org)
  • Our consortium aims to investigate novel non-invasive tools to quantify microvascular health and rarefaction in both organs, as well as surrogate biomarkers for cerebral and/or cardiac rarefaction (via sublingual capillary health, vascular density of the retina, and RNA content of circulating extracellular vesicles), and to determine whether microvascular density relates to disease severity.Methods/design: The clinical research program of CRUCIAL consists of four observational cohort studies. (unav.edu)
  • The results that the authors show are very competitive and seem to beat SOA methods. (nips.cc)
  • The 3 methods showed good discriminatory ability. (bvsalud.org)
  • In this study 465 clinical samples were tested using PCR and the results obtained indicates that this approach offers may advantages over conventional methods and could be used to detect Mycobacterium tuberculosis in clinical samples. (who.int)
  • The results of the study showed that irradiated samples of carbon-doped porous silicon have better photoluminescence compared to nonirradiated samples. (hindawi.com)
  • The reproducibility study, focusing on the 13 parameters of the device, consisted of repeating three races at three different speeds (8, 12 and 16 km/h), 3 weeks apart. (minervamedica.it)
  • The CTPA sensitivity in that paper is consistent with the 83% result quoted in the recent prospective multicenter PIOPED 2 study ( 6 ). (snmjournals.org)
  • One particularly interesting approach is to have studies pre-registered , which emphasizes study design over results. (nautil.us)
  • I recently proposed a publishing model that may increase the tendency to publish negative and confirmatory results by decreasing the minimum amount of information a new study needs to provide. (nautil.us)
  • Key results of the study include an examination of the sensitivity of Mastermind for variant interpretation. (prweb.com)
  • We have conducted experimental campaign to study, for the first time, the effect of hydrodynamic cavitation on liposome stability and compare it to the effect of well described chemical, physical and mechanical treatments. (europa.eu)
  • We show that this approach provides a basis for determining comparability, hence for comparison of evaluations across papers, meta-evaluation experiments, reproducibility testing. (dcu.ie)
  • Participants will be initially asked to make predictions on the reproducibility of 20 experiments in a survey. (bmj.com)
  • Once they complete the survey, they will enter the markets, in which they will receive credit to bet on the results of individual experiments in a stock market-like environment along with other participants. (bmj.com)
  • Carefully worked experiments on 5 datasets and 2 tasks show consistent and significant improvements w.r.t. the baselines. (nips.cc)
  • NT-proBNP plasma and urine levels show good stability in a 24-month follow-up of patients with stable heart failure. (bmj.com)
  • The method of the HPLC fingerprint chromatogram is of good precision, reproducibility and stability,which is suitable for quality control of cell wall-broken decoction pieces of Notoginseng. (unboundmedicine.com)
  • These results showed that HIV-O genetic diversity still has an impact on RNA quantification. (scienceopen.com)
  • The paper shows how a computationally intelligent approach to building a search engine for genetic evidence has quickly surpassed two decades of manual effort in building static genetic databases. (prweb.com)
  • Manual curation of about a hundred genetic variants for each participant required a median of 54 minutes per variant, resulting in moderate classification agreement between professionals. (cdc.gov)
  • The graphite furnace atomic absorption spectrophotometer is equipped with an automatic sampler, has accurate sample determination results and has good precision, but it has strict requirements of experimental conditions and demands for a large current and high voltage. (justia.com)
  • Scientific reproducibility has been at the forefront of many news stories and there exist numerous initiatives to help address this problem. (researchgate.net)
  • Scientific efficiency and reproducibility depend upon a research-wide improvement of this substantial problem in science today. (researchgate.net)
  • L ast month a long thread evolved on Hacker News, a popular discussion forum, in response to my Nautilus article, " We Should Not Accept Scientific Results That Have Not Been Repeated . (nautil.us)
  • It has worked very well, despite both animal ethics and scientific concerns - which is why no one has really tackled developing a medium with defined content and without animal proteins. (lu.se)
  • The gene expression profiler did not perform noticeably better than indices con- structed from the clinical variables, e.g., the well established NPI. (lu.se)
  • Current standards for designing and reporting human evaluations in NLP mean it is generally unclear which evaluations are comparable and can be expected to yield similar results when applied to the same system outputs. (dcu.ie)
  • Awareness of reproducibility issues in various areas of science has been on the rise in recent years, with systematic replication efforts in areas such as psychology , economics , cancer biology and social sciences arising in recent years. (bmj.com)
  • The question of whether researchers can estimate the reproducibility of published findings has been studied in replication initiatives in psychology (see also this ), economics and social sciences , and the answer is that they are reasonably good at it. (bmj.com)
  • It was even demonstrated that laypeople without a PhD in psychology show some accuracy in predicting reproducibility in these studies. (bmj.com)
  • Objective Transcranial sonography (TCS) shows characteristic hyperechogenicity of the substantia nigra (SN) in patients with Parkinson's disease (PD). (bmj.com)
  • COPD affects nearly 20 percent of the adult U.S. population and includes such conditions as asthma, chronic bronchitis and emphysema, as well as occupationally related lung disorders. (cdc.gov)
  • Scales (n = 10) were tested for internal consistency, floor-ceiling effect, and reproducibility for which participants completed the PEQ twice within a 2-week interval. (nih.gov)
  • Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in glioblastoma (GB) cell lines. (nature.com)
  • Subsequent studies showed that the virus is responsible worldwide for a proportion of community-acquired acute respiratory tract infections in children ( 2 - 4 ), as well as other age groups ( 5 - 9 ). (cdc.gov)
  • During the first 2.5 years of the project, we have conducted a review of the current understanding of the mechanisms taking place behind the phenomenon and proposed guidelines which should be followed to ensure reproducibility and clearness of the studies and to avoid oversimplification of the problem and uncritical dissemination of the conclusions over various application areas. (europa.eu)
  • Information from NHANES III pulmonary studies will be used to provide reference data for occupational exposure research, air quality studies, and specialized cardiovascular research, as well as documentation of the relationship of smoking to COPD. (cdc.gov)
  • Whether reproducibility can be accurately estimated from published information has major implications not only for choosing what to believe or what is worth replicating, but also for how we assess and fund science. (bmj.com)
  • We first show that the present Kanzaki model may reproduce very accurately the LLD energies obtained by the direct FPKKR calculations with the restriction on the displacement of only the 1st-nearest neighboring atoms around a single impurity X in Al, although the discrepancy increases with the atomic-size misfit between Al and X atoms. (go.jp)
  • Three panels, each with 8 to 16 isolates, were typed at all laboratories, resulting in 280 images. (cdc.gov)
  • Standardization of this technique promises the best results for direct comparison of large numbers of genotype patterns obtained in different laboratories ( 2 - 4 ). (cdc.gov)
  • Results As expected, the authors found significant bilateral SN hyperechogenicity in PD patients. (bmj.com)
  • Results: Of the 30 patients analyzed, classified by the Index of Bilateral resulted in 10% grade 1, 36.6% grade 2, 36.6% grade 3, 13.33% grade 4 and 3.33% grade 5. (bvsalud.org)
  • Longtitudinal ultrasound shows synovitis, neovascularity, and early erosion of metacarpal head. (diagnosticimaging.com)
  • patients showed no response to antimicrobial drugs prescribed for typical and atypical pneumonia (β-lactams, macrolides, and fluoroquinolones). (cdc.gov)
  • Results From a total of 2000 lesions, 323 SSA/Ps in 246 patients and 1527 adenomas in 1425 patients were included for analysis. (bmj.com)
  • Results A total of 27 patients (84.4%) experienced splenic switch-off according to first-pass categories. (unav.edu)
  • We're excited to have you here for our debate: Should patients have immediate access to cancer test results via electronic health records (EHRs)? (medscape.com)
  • Now, the intention clearly is good: Patients should have access to the records. (medscape.com)
  • You know our patients are getting their test results and are misunderstanding them. (medscape.com)
  • Reproducibility and responsiveness were high among both stable and unstable asthma patients. (who.int)
  • Conclusions: There was a high concentration of patients in good and regular forecasts, without regard to gender or the rehabilitation hospital for surgery. (bvsalud.org)
  • Access to laboratory test results through patient portals is a health equity issue for patients with limited English proficiency (LEP), particularly for Spanish-speaking patients, the largest minority group in the USA. (cdc.gov)
  • Natural rubber (NR) is a raw material that is widely used in a variety of industries owing to its outstanding properties such as its high stress at break, good tear resistance, low heat build up and good tack. (iucr.org)
  • As a result, airflow resistance decreases as air moves from the large airways to the smaller bronchioli. (cdc.gov)
  • The graphite furnace has an input power of 4000 VA and an input voltage of 380 V. The graphite tube is consumable and easy to damage, and thus is suitable for use in a laboratory with good conditions. (justia.com)
  • In particular, the excellent mechanical properties of graphene make it a potentially good reinforcement ingredient in ceramic composites while their impressive electrical conductivity has roused interest in the area of multifunctional applications. (springer.com)
  • Pain syndromes in the neck-shoulder region resulting in neck sprain after repetitive mechanical loads imposed on the neck and shoulders during car or sporting accidents do not appear to be an isolated phenomenon. (iospress.com)
  • To our knowledge, this is the first in vivo example where mechanical force has been shown to polarize Pins to mediate division orientation. (elifesciences.org)
  • Significant correlations were observed between the 15 D index and the scales for ambulation, social burden, usefulness, and well-being. (nih.gov)
  • Only 16% had a poor prognosis, and prognosis associated with the gender showed no statistically significant difference (p = 0.207) during the application of the Likelihood Ratio Test. (bvsalud.org)
  • For the women, there was a significant difference between the AUDIT-3 and AUDIT-C. Both the complete version of AUDIT and its reduced forms presented good discriminatory ability. (bvsalud.org)
  • Conclusion: A modified diet history method combining a food record and a food frequency questionnaire shows good reproducibiiity. (lu.se)
  • La validité et la fiabilité d'une traduction en arabe adaptée du questionnaire sur la qualité de vie des enfants asthmatiques (PAQLQ-A) pour les enfants égyptiens a été évaluée dans une cohorte de 103 enfants asthmatiques âgés de 8 à 16 ans. (who.int)
  • There are major reproducibility problems in research. (lu.se)
  • Results obtained from Restriction fragment length polymorphism typing show that the mahority of circulating Mycobacterium tuberculosis strains in Sri Lanka belong to a limited number of families, but the degree of IS6160 DNA polymorphism among strains were high. (who.int)
  • More than 68 percent had less than 5 copies of the IS sequence suggesting that our local M.tuberculosis strains have a fewer number of copies compared to data shown in most countries. (who.int)
  • Replications will occur within a countrywide network along the course of 2020, with results due in mid-2021. (bmj.com)
  • It took until 2023 before the results were published. (lu.se)
  • In this paper, 40% of negative CTPA results were false-negative if the clinical suspicion was high, and 42% of positive scan results were false-positive if the clinical suspicion was low. (snmjournals.org)
  • Unfortunately associated well-being and it is important for a good and consistent risk factors were never seriously investigated. (who.int)
  • and do show some improvements. (ucsd.edu)
  • Their worldwide adverse impacts on well-being, that the 12- and 15-year-old children and adolescents had quality of life and systemic health are well document- a higher prevalence of caries history in permanent teeth ed ( 3 ). (who.int)
  • RESULTS: The Myotest showed a good to excellent reproducibility (ICC>0.70) for the three running speeds, except for two parameters: asymmetry and regularity index. (minervamedica.it)
  • The specific treatment approach is chosen in accordance with the type and degree of pelvic organ prolapse, as well as the severity of symptoms. (medscape.com)
  • However, its application is now quite limited because results vary depending on the degree of polish of the electrode, and reproducibility is low. (horiba.com)
  • The success of modeling depends on the accuracy in simulating the geometry and surface structure of the tooth, the material characteristics of the tooth and jawbone, the loading and support conditions as well as the biomechanical tooth-jawbone interface. (hindawi.com)
  • Finally, the resulting embeddings are fed through Euclidean and hyperbolic softmax MLR layers for node and edge classification tasks. (nips.cc)
  • Using common sense in laboratory science, however, is likely to be harder - unless you are an expert in the field, you will hardly have a good intuition of whether overexpressing protein X is likely to lead to an increase in the expression of gene Y. (bmj.com)
  • The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)
  • Results: The concentration of DHA appeared to be higher in erythrocyte and breast milk samples of the DHA-supplemented group at all subsequent time points. (bvsalud.org)