Indocyanine green angiographyDiabetic retinopathyOphthalmicOCTAFundus photographyClinicalOpticalLeakageOcularFindingsMacularIntraocularProcedure is performedSodiumRetinaVascular occlusionVesselsUnderwentMinimally classicLesionsVitrectomyAngiogramsMicroscopyIntravascularPatientsProliferativeDetectSurgeryInflammationExtentCommonlyDiagnosisCorneal2023AbnormallyEyesAssessmentColorBlood flowVisionKeywordsVisualCommonEarlyStudyTreatmentPhase
Indocyanine green angiography4
- Indocyanine green angiography (ICGA) was used to re-evaluate eyes for PCV. (bmj.com)
- 5 , 7 , 8 Why some patients have a poor response to ranibizumab is not well understood, but use of indocyanine green angiography (ICGA) has revealed the presence of polypoidal choroidal vasculopathy (PCV) in several patients with neovascular AMD who did not respond to repeated injections of anti-VEGF agents. (bmj.com)
- Indocyanine green angiography (ICGA) is an effective tool for identifying hypoperfused areas. (thieme-connect.de)
- All patients underwent a complete ophthalmic examination, including fluorescein and indocyanine green angiography (ICGA). (elsevierpure.com)
Diabetic retinopathy6
- Diabetic retinopathy is damage to the retina (the transparent, light-sensitive structure at the back of the eye) as a result of diabetes. (msdmanuals.com)
- Proliferative diabetic retinopathy results in greater loss of vision than does nonproliferative diabetic retinopathy. (msdmanuals.com)
- Initially, diabetic retinopathy may not manifest any symptoms or may only result in minor vision issues. (factmr.com)
- Fluorescein angiography and optical coherence tomography scans are currently the most accurate clinical methods for diagnosing diabetic retinopathy. (edu.au)
- To compare optical coherence tomography angiography (OCTA) findings between severe non-proliferative diabetic retinopathy (NPDR) and unexposed proliferative diabetic retinopathy (PDR), and identify predictive factors. (jkos.org)
- A. Early phase fluorescein angiography of a patient with non-proliferative diabetic retinopathy. (reviewofophthalmology.com)
Ophthalmic3
- Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. (who.int)
- Preoperative iris fluorescein angiograms (IFA) and ophthalmic records of 34 diabetic patients who underwent vitrectomy were reviewed. (unboundmedicine.com)
- Albrecht von Graefe's archive for clinical and experimental ophthalmology JO - Albrecht Von Graefes Arch Klin Exp Ophthalmol VL - 206 IS - 1 N2 - Preoperative iris fluorescein angiograms (IFA) and ophthalmic records of 34 diabetic patients who underwent vitrectomy were reviewed. (unboundmedicine.com)
OCTA5
- D Dioptres, AL Axial length, FA Fluorescein angiography, OCTA Optical coherence tomography angiography, SD-OCT Spectral domain optical coherence tomography, mCNV Myopic choroidal neovascularisation. (medscape.org)
- Purpose To compare swept source OCTA device, with and without the extended field imaging (EFI) technique, to standard fluorescein angiography (FA) in the clinical practice. (unimi.it)
- Purpose To evaluate the morphological structure of illdefined choroidal neovascularisation (CNV) with traditional fluorescein angiography (FA) compared with optical coherence tomographic angiography (OCTA). (elsevierpure.com)
- Conclusions Although the sample size is small to draw conclusions and the nature of work is retrospective and descriptive, OCTA has the potential to improve visualisation of ill-defined CNV with dye-based angiography, including occult CNV. (elsevierpure.com)
- En face OCT reflectance images which accompany OCTA studies offer a glimpse of the macrophage-like cellular activity above the retinal surface which responds to systemically instigated vascular events below. (stanford.edu)
Fundus photography2
- Although the study used color fundus photography, FAF, fluorescein angiography, and OCT, it did not include OCT angiography, which can noninvasively detect the presence of macular neovascularization. (aao.org)
- Unexposed PDR was diagnosed using fluorescein fundus angiography, because new vessels could not be observed in the poster pole or clearly distinguished in the retinal periphery on wide fundus photography. (jkos.org)
Clinical4
- The RAINBOW results are consistent with the VIEW clinical studies. (bmj.com)
- Our AI-driven approach delivers results that are just as accurate as clinical scans but relies on retinal images that can be generated with ordinary optometry equipment. (edu.au)
- A clinical study of 500 eyes comparing results of CONTOURA ® Laser Vision Correction with Phorcides Analytic Engine in low versus high myopia. (digitalproducer.com)
- the dogs underwent clinical examination, fluorescein angiography, and histologic examination. (unifesp.br)
Optical6
- Photographic tests called fluorescein angiography or optical coherence tomography may be done in order to determine the extent of the damage on the underlying retina. (floridaretinacenter.com)
- It includes new images, new chapters, and new data derived from exploration of retinal periphery and advances in optical coherence tomography (OCT) and OCT-angiography. (surgerybook.net)
- Optical coherence tomography and fluorescein angiography (FA) were performed before treatment and at subsequent follow-up examinations in all eyes. (qxmd.com)
- Optical coherence tomography appears to be useful in monitoring the retinal changes that occur following PDT of CNV and may assist in understanding the changes observed on angiography. (qxmd.com)
- Since then, my research has focused on the advancement of optical technologies for improving the understanding, diagnosing and monitoring of conditions that result in vision loss. (stanford.edu)
- Ghassemi F, Fadakar K, Bazvand F, Mirshahi R, Mohebbi M, Sabour S. The quantitative measurements of vascular density and flow areas of macula using optical coherence tomography angiography in normal volunteers. (jamanetwork.com)
Leakage4
- Disc redness in a fundus photograph (upper left) and slight leakage from the disc in fluorescein angiography (FA, upper right) were observed at the 8-week (8W) evaluation. (neurosciencenews.com)
- No fluorescein leakage is present. (arizona.edu)
- No vascular leakage is seen on fluorescein angiography. (arizona.edu)
- Microaneurysms are seen most prominently temporal to the fovea in addition to fluorescein leakage in the foveal avascular zone. (reviewofophthalmology.com)
Ocular3
- Excessive use of computers can result in ocular fatigue and other symptoms. (apollohospitals.com)
- Attempts at grouping these myriad disorders, especially by Gass, have resulted in inclusion of multiple evanescent white dot syndrome (MEWDS), acute idiopathic blind spot enlargement syndrome (AIBSES), acute macular neuroretinopathy (AMN), and multifocal choroiditis (MFC) or pseudo-presumed ocular histoplasmosis (pseudo-POHS) under the term acute zonal occult outer retinopathy (AZOOR). (medscape.com)
- SIOL results from ocular metastasis originating from outside the CNS. (medscape.com)
Findings1
- Results of this study reinforce previous safety and efficacy findings, showing that ACP is well tolerated and that GA lesion growth was significantly reduced with both ACP 2 mg and ACP 4 mg. (aao.org)
Macular5
- To evaluate the visual and anatomic results of macular hole surgery in eyes that have had symptoms of a macular hole for 2 years or longer. (nih.gov)
- Eyes with macular holes between 2-2.99 years experienced a somewhat better anatomic and functional result overall than eyes with macular hole from 3-14 years, duration, but the visual acuity change was not statistically significant (P = 0.187). (nih.gov)
- Results of the 2-part, 18-month GATHER1 trial suggest that avacincaptad pegol can significantly reduce the progression of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) with few adverse effects. (aao.org)
- Multipoint analysis resulted in a peak lod score of 6.2 in the interval between markers D6S313 and D6S252 and excluded the interval containing the North Carolina macular dystrophy gene. (nih.gov)
- This cystoid macular edema (CME) results most commonly from inflammation, localized traction, or following surgery. (reviewofophthalmology.com)
Intraocular2
- The role of nestin was examined using angiography, western blot from the second to the 14th day after laser impacts, and intraocular injection of nestin siRNA. (molvis.org)
- The intraocular and fluorescein angiography confirmed the complete vascular occlusion as the main pa- thology (Figure 2). (who.int)
Procedure is performed1
- A fluorescein angiography procedure is performed by an ophthalmologist along with another doctor like a surgeon being close by to monitor for side-effects to the dye. (medicalhealthtests.com)
Sodium5
- The dye called sodium fluorescein is a toxic substance that can immediately alter the pH balance in the blood. (medicalhealthtests.com)
- Fluorescein sodium, the sodium salt of fluorescein, is used extensively as a diagnostic tool in the field of ophthalmology and optometry, where topical fluorescein is used in the diagnosis of corneal abrasions, corneal ulcers and herpetic corneal infections. (wikipedia.org)
- It is available as sterile single-use sachets containing lint-free paper applicators soaked in fluorescein sodium solution. (wikipedia.org)
- A fluorescein angiogram is a test where sodium fluorescein dye is injected into the veins of your hand or arm and a series of photographs are taken of your retina. (floridaretinacenter.com)
- Patients who are allergic to x-ray dye are not necessarily allergic to sodium fluorescein. (floridaretinacenter.com)
Retina5
- The association between visual acuity and both the neurosensory retina and the SRT was stronger for lesions classified as minimally classic or occult on fluorescein angiography. (nih.gov)
- The fluorescein angiogram allows the physician to evaluate the blood vessels in the retina as well as the retinal layer and the layer underneath the retina. (floridaretinacenter.com)
- A novel retina imaging technique using the NGENUITY ® 3D Visualization System unveiled by surgeons seeking to develop more efficient methods for fluorescein angiography. (digitalproducer.com)
- In the normal eye, fluorescein is prevented from passing into the retina by the blood-retinal barriers. (reviewofophthalmology.com)
- In ME, however, fluorescein molecules leave the intravascular space to enter the retina. (reviewofophthalmology.com)
Vascular occlusion1
- The rigid sickled erythrocytes lead to vascular occlusion, which results in retinal hypoxia, ischemia, and neovascularization. (medscape.com)
Vessels4
- As observed on angiography, the numbers of choroidal and retinal blood vessels were significantly increased (principally on the seventh day) after the laser impacts. (molvis.org)
- If this series of events does not stabilize or reverse with recanalization of the occluded retinal vessels, the subsequent end-stage results may be retinal infarction and/or detachment. (medscape.com)
- Fluorescein angiography is the practice of taking photographs of blood vessels inside the eye (an angiogram) with the help of a contrast dye (fluorescein dye). (floridaretinacenter.com)
- Looking at the multimodal imaging, we were surprised to find out that these anomalous vessels were veins in 100% of the cases (a few arteries are described in literature but with no actual fluorescein angiography)," said Dr. Francesco Pichi of the Cleveland Clinic Abu Dhabi, Eye Institute, United Arab Emirates. (medscape.com)
Underwent1
- At 4 years of age, she underwent right lateral rectus resection resulting in improved cosmesis and a small amount of consecutive exotropia. (uiowa.edu)
Minimally classic1
- 1 The widespread use of ranibizumab intravitreal injection for the treatment of this condition was based on results from the pivotal Phase III Minimally Classic/Occult Trial of the Anti-VEGF Antibody Ranibizumab in the Treatment of Neo-vas-cular AMD (MARINA) and Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularisation in AMD (ANCHOR) studies. (bmj.com)
Lesions1
- In addition, the results may not be generalizable to subfoveal lesions as only non-subfoveal lesions were included. (aao.org)
Vitrectomy4
- or = 2 years' duration) were treated in a retrospective analysis of the results of vitrectomy, 16% perfluoropropane gas tamponade, and one of three adjunctive agents (bovine transforming growth factor beta-2, recombinant transforming growth factor beta-2, or autologous platelet extract). (nih.gov)
- Zakov ZN, Lewis ML. Iris fluorescein angiography in diabetic vitrectomy patients. (unboundmedicine.com)
- TY - JOUR T1 - Iris fluorescein angiography in diabetic vitrectomy patients. (unboundmedicine.com)
- The en face infrared (IR) image on the left demonstrates the "water mark" where the peripapillary subretinal fluid resolved following pars plana vitrectomy with release of traction. (uiowa.edu)
Angiograms1
- En face OCT angiograms were compared with FA. (elsevierpure.com)
Microscopy2
- Fluorescein is a fluorophore commonly used in microscopy, in a type of dye laser as the gain medium, in forensics and serology to detect latent blood stains, and in dye tracing. (wikipedia.org)
- To observe the accumulation of conjugate, 3 rabbits with CNV received rhodamine B isothiocyanate-binding PVA (RITC-PVA), and the lesion was studied 24 hours later by fluorescein microscopy. (arvojournals.org)
Intravascular1
- Main outcome measures were: Achievement of prolonged intravascular infusionof t-PA, changes in fundus appearance, fluorescein angiography, and histology.RESULTS: A microcatheter instrument and a surgical technique for retinal vein cannulation with prolonged intravascular infusion were developed. (unifesp.br)
Patients7
- Anterior segment fluorescein angiography has been used in the investigation of patients with sclerokeratitis. (bmj.com)
- Hepatitis B viral mutants can emerge in patients as a result of selection pressure from either immune response or treatment options. (cdc.gov)
- Results Forty-three eyes of 27 patients were included. (unimi.it)
- Patients who undergo a fluorescein angiogram often get a mild yellow discoloration of their skin. (floridaretinacenter.com)
- The results demonstrated that adding blue laser did not negatively affect the noninvasive, easy-to-acquire images in patients with a small pupil when using the patient-friendly and high-resolution images obtained using previous UWF devices. (ophthalmologytimes.com)
- Rhegmatogenous retinal detachment (RRD) is the most common form of retinal detachment (RD). Proliferative vitreoretinopathy (PVR) is primarily a result of failure to correct RRD after initial retinal reattachment surgery, occurs in 5%-10% of patients, and may lead to recurrent RD. 1 Further surgery is the only proven therapy for recurrent RD with PVR. (dovepress.com)
- Results: Of the 321 patients (392 eyes), 79 (98 eyes, 24.6%) were diagnosed with PCV. (elsevierpure.com)
Proliferative1
- Although many hemoglobinopathies exist, those resulting in proliferative retinopathy are limited to sickle cell disease. (medscape.com)
Detect1
- Fluorescein angiography was performed to detect the area with CNV, and the evaluation was made by computerized measurement of digital images. (arvojournals.org)
Surgery3
- The changes arose either as a result of a systemic vasculitis in seropositive individuals or were induced by surgery to the eye. (bmj.com)
- At 8 weeks (8W) after surgery, the results of color fundus photographs (upper left) and FA (upper right) revealed no inflammation. (neurosciencenews.com)
- Optimizing Indocyanine Green Fluorescence Angiography in Reconstructive Flap Surgery: A Systematic Review and Ex Vivo Experiments. (thieme-connect.de)
Inflammation2
- [ 3 ] suggested an ischemic choroidopathy, which resulted from primary inflammation of the choriocapillaris, as the unifying pathogenesis of these diseases. (medscape.com)
- Membranes may also result from eye conditions or diseases such as retinal detachment, inflammation, injury or vascular conditions. (floridaretinacenter.com)
Extent1
- The extent to which fluorescein dilaurate is broken down to yield lauric acid can be detected as a measure of pancreatic esterase activity. (wikipedia.org)
Commonly1
- In procedures such as fundus imaging, fluorescein angiography, paired optic disc pictures, and external photography, fundus cameras are most commonly employed. (factmr.com)
Diagnosis2
- Fluorescein angiography in the differential diagnosis of sclerokeratitis. (bmj.com)
- Fluorescein angiography is an essential tool in the diagnosis of ME. (reviewofophthalmology.com)
Corneal4
- Any disease affecting this structure results in loss of corneal clarity and thereby affecting vision. (apollohospitals.com)
- Corneal scarring can result from infections and trauma (mechanical, thermal or chemical). (apollohospitals.com)
- Abnormalities in corneal shape like keratoconus result from inherent structural abnormally and also affect vision. (apollohospitals.com)
- The innermost layer of the corneal may become dysfunctional in certain conditions and result in clouding of the cornea. (apollohospitals.com)
20231
- Based on the results reported at the ARVO 2023 Annual Meeting, Optos issued a press release in late May 2023 regarding its decision to expand the optomap UWF retinal imaging modalities available with the California fluorescein angiography device to include the first UWF color RGB image. (ophthalmologytimes.com)
Abnormally1
- The IGFBP7 gene mutation that causes RAMSVPS results in an abnormally short IGFBP7 protein that does not function properly. (medlineplus.gov)
Eyes1
- Fluorescein angiography demonstrated improved circulatory flow in treated relative to non, treated eyes. (unifesp.br)
Assessment1
- Invited Session V: The eye as a window to systemic and neurodegenerative health: Seeking Answers through a keyhole: Harnessing the Synergy of Dynamic OCT/OCT Angiography and Adaptive Optics SLO for Retinal Assessment of Systemic Disease. (stanford.edu)
Color2
- The color of its aqueous solutions is green by reflection and orange by transmission (its spectral properties are dependent on pH of the solution), as can be noticed in bubble levels, for example, in which fluorescein is added as a colorant to the alcohol filling the tube in order to increase the visibility of the air bubble contained within. (wikipedia.org)
- Fluorescein is also known as a color additive (D&C Yellow no. 7). (wikipedia.org)
Blood flow2
- The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to distinguish blood flow from static tissue. (elsevierpure.com)
- The next phases of fluorescein angiography showed the blood flow in the affected artery. (who.int)
Vision1
- POTIGA can cause retinal abnormalities with funduscopic features similar to those seen in retinal pigment dystrophies, which are known to result in damage to the photoreceptors and vision loss. (drugs.com)
Keywords1
- Use - to remove results with certain keywords. (msdmanuals.com)
Visual1
- Any disease affecting this layer results in the visual disturbance. (apollohospitals.com)
Common2
- NHS-fluorescein, is another common amine-reactive derivative, yielding amide adducts that are more stable than the aforementioned thioureas. (wikipedia.org)
- The hemoglobinopathy results from inheriting 1 Hb S gene and 1 Hb C gene, which is common in West African populations. (medscape.com)
Early1
- Dexamethasone is a potent water-soluble glucocorticoid that was first administered by intravitreal injection as an adjunct in experimental endophthalmitis as early as in 1974 with beneficial results. (dovepress.com)
Study3
- In a separate study published in the same issue of Stem Cell Reports , the researchers saw similar results when they repeated this last experiment with human T cells and HLA-matched or unmatched retinal pigment cells grown from IPSCs. (neurosciencenews.com)
- Results Eleven cases of ill-defined CNV on FA were identified from 10 study participants. (elsevierpure.com)
- Results Sixty-nine flaps were included in the study. (thieme-connect.de)
Treatment1
- These results suggest that TNP-470-PVA inhibited the proliferation of HUVECs more sensitively than that of BRPECs, and the targeted delivery of TNP-470-PVA may have potential as a treatment modality for CNV. (arvojournals.org)
Phase1
- Results of the longer-term, phase 3 GATHER2 trial are pending. (aao.org)