InsulinDiabetes Mellitus, Type 1Protein KinasesProtein Kinase CReceptor, InsulinPhosphorylationCyclic AMP-Dependent Protein KinasesCalcium-Calmodulin-Dependent Protein KinasesPhosphatidylinositol 3-KinasesSignal TransductionEnzyme ActivationProtein-Serine-Threonine KinasesProtein Kinase InhibitorsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Insulin AntibodiesCalcium-Calmodulin-Dependent Protein Kinase Type 1Cyclic GMP-Dependent Protein KinasesCyclic AMPInsulin ResistanceMolecular Sequence DataKineticsCells, CulturedAlbuminuriaCell LineAmino Acid SequenceMitogen-Activated Protein KinasesPhosphatidylinositolsEnzyme InhibitorsIsoenzymesMAP Kinase Signaling SystemCalmodulinGlucoseDiabetic KetoacidosisInsulin Receptor Substrate ProteinsIslets of Langerhansp38 Mitogen-Activated Protein KinasesParamecium tetraureliaProtein BindingDiseases in TwinsTwins, MonozygoticTime FactorsPhosphoproteinsProto-Oncogene Proteins c-aktTetradecanoylphorbol AcetateHemoglobin A, GlycosylatedMitogen-Activated Protein Kinase 1eIF-2 KinaseSubstrate SpecificityProtein Kinase C-alphaHypoglycemiaInsulin Infusion SystemsDiabetes Mellitus, Type 2Blood GlucoseMutationBlotting, WesternTransfectionMitogen-Activated Protein Kinase 3Cyclic AMP-Dependent Protein Kinase Catalytic SubunitsMitogen-Activated Protein Kinase KinasesDiabetic NephropathiesInsulin, Long-ActingBase SequenceHypoglycemic AgentsComplement C4Binding SitesCyclic GMPRats, Sprague-DawleyC-PeptideRNA, MessengerDose-Response Relationship, DrugProtein Kinase C-deltaJNK Mitogen-Activated Protein KinasesInsulin AntagonistsAndrostadienesCalcium-Binding ProteinsAdenosine TriphosphatePregnancy in DiabeticsCyclic AMP-Dependent Protein Kinase Type IIPhosphoprotein PhosphatasesProtein-Tyrosine KinasesCattleSerineDiabetic DietCell MembraneAMP-Activated Protein KinasesDiabetes MellitusIsoquinolinesModels, BiologicalRecombinant Fusion ProteinsGene Expression RegulationRecombinant ProteinsPhosphatidylinositol PhosphatesChromonesPeptide TCarrier ProteinsDiabetic Retinopathy1-(5-Isoquinolinesulfonyl)-2-MethylpiperazineApoptosisCyclic GMP-Dependent Protein Kinase Type I