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  • systemic inflamma
  • In addition to specific signs and symptoms directly related to the venom toxic components, patients bitten by venomous snakes, hymenoptera insects, spiders, and scorpions may develop a systemic inflammatory response syndrome. (scielo.br)
  • The received data have become important in the determination of increased number of criteria of systemic inflammatory response syndrome depending on the outcomes of the burn injury and endothelial dysfunction development. (ssmj.ru)
  • interleukin
  • The following cytokines were measured using Cytometric Bead Array: interleukin-1beta (IL-1beta), IL-6, tumour necrosis factor-alpha, IL-8, IL-12 and IL-10 (B&D). Thirteen patients took part in the study (67 +/- 9 years). (lsh.is)
  • They evaluated key cytokines like interleukin-10 (IL-10), cellular processes related to immunity, and the resulting IUGR phenotype and placental histopathology to determine the immunologic pathways affected by IUGR. (immunesystem.news)
  • markers
  • Poisson regression was used to analyze the relation between inflammatory markers measured on 1) ICU admission and day 4 mortality, 2) day 4 and day 28 mortality, and 3) ICU discharge and 1-year mortality. (uu.nl)
  • aberrant
  • Our data demonstrate that chronically elevated brain CRH levels produce marked changes in basal (largely CRH regulated) physiological and behavioral processes accompanied by aberrant responses to an acute challenge. (jneurosci.org)
  • expression
  • By activating the TLR4 signalling cascade with bacterial lipoploysaccharide (LPS), we investigated whether TLR4 influenced matrix metalloproteases (MMP-2, MMP-9) and cytokine expression in diseased human primary corneal fibroblast (CF) cells are altered. (arvojournals.org)
  • Hepcidin expression in mammals is regulated transcriptionally, increasing in response to iron supplementation and decreasing in response to iron need ( 4 ). (pubmedcentralcanada.ca)
  • We conclude that sesamol regulates leucocyte and macrophage PPAR-γ-associated systemic cytokines expression, thereby ameliorates acute kidney injury and hypotension in rats. (tu-dortmund.de)
  • Further, we evaluated glucosyltransferase (GT) activity in regulation of toxin-induced cytokine expression. (asm.org)
  • significantly
  • 100 μg/kg body weight] on day 7 of CRH/vehicle treatment produced a marked fever response in control animals, which was significantly blunted in intracerebroventricularly CRH-treated rats. (jneurosci.org)
  • Although free corticosterone levels reached similar peak concentrations in both intracerebroventricularly vehicle- and CRH-infused groups after LPS, this response was delayed significantly by ∼1 hr in the intracerebroventricularly CRH-treated animals. (jneurosci.org)
  • macrophage
  • The CD14 + -depleted cultures no longer produced significant amounts of macrophage-derived cytokines like IL-1 and TNF-α. (biomedcentral.com)
  • 2 After macrophage foam cell formation, Mø are thought to contribute to lesion progression through a variety of interactions with other cells of the artery wall that depend on the elucidation of a host of cytokines and growth factors by cells residing in the intima. (ahajournals.org)
  • immunological
  • We hypothesized that act of performing a Pap smear is associated with inflammatory responses at the site of trauma, the cervix, and that this inflammatory signalling may be an immunological factor initiating these productive anti-HPV responses. (uct.ac.za)
  • These results might indicate that the lesions in the recAgs group were due not only to the mites density but also to an exacerbated immunological response after challenge, which is in agreement with the specific high levels of pro-inflammatory cytokines (IL-1 and TNFα) detected after challenge in this group. (biomedcentral.com)
  • vascular
  • They found that maternal FR decreases the anti-inflammatory effect of IL-10 and suppresses placental autophagic and ER stress responses, despite the presence of dysregulated vascular and trophoblast structures that lead to IUGR. (immunesystem.news)
  • protein
  • In the article titled, "Pro-inflammatory cytokine response and genetic diversity in merozoite surface protein 2 of Plasmodium falciparum isolates from Nigeria", DOI: 10.4103/2277-9175.192631 of Advanced Biomedical Research[ 1 ], the reference numbers cited in the three sentences in the "Result" section of the article are incorrect. (pubmedcentralcanada.ca)
  • The results indicated that neutralisation of both IL-1 and TNF-α was needed to achieve a degree of cytokine (IL-6, IL-8, and monocyte chemoattractant protein-1) and matrix metalloproteinase (1, 3, 9, and 13) inhibition, as assessed by enzyme-linked immunosorbent assay and by reverse transcription-polymerase chain reaction (RT-PCR), similar to that observed in CD14 + -depleted cultures. (biomedcentral.com)
  • study
  • The aim of this study was to measure the central nervous system (CNS) cytokine response following resuscitation from ventricular fibrillation (VF) in a porcine model of cardiac arrest and global hypoxic ischemia. (ahajournals.org)
  • cascade
  • A better understanding of the involvement of the inflammatory cascade in different envenoming syndromes may have future therapeutic benefits. (scielo.br)
  • immune responses
  • In this sense, and given that previous studies have shown some degree of protective immune responses developed after S. scabiei infestation [ 10 - 15 ], vaccination seems to be a good ecological alternative to the use of acaricides for parasite control. (biomedcentral.com)
  • rats
  • Injection of LPS in intracerebroventricularly CRH-treated rats produced a blunted 5-HT response and a delayed onset of behavioral inhibition and other signs of sickness behavior. (jneurosci.org)
  • role
  • In addition to confirming prior reports on the role of IL-8, IL-1β, and IL-6 in CDI, our data suggest that IL-16 and IL-17A, as well as the IL-1β/Th17 axis, play a key role in driving inflammatory responses in CDI. (asm.org)