Response genotoxic stress. Medical search. Frequent questions

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Anatomy20

Cell Line, Tumor Cell Line Micronuclei, Chromosome-Defective HCT116 Cells Fibroblasts Cell Nucleus HeLa Cells Cells, Cultured HEK293 Cells Tumor Cells, Cultured Cell Line, Transformed Chromatin NIH 3T3 Cells Lymphocytes Mitochondria Cytoplasm Embryo, Mammalian Keratinocytes 3T3 Cells Epithelial Cells

Organisms8

Mice, Knockout Mice, Inbred C57BL Saccharomyces cerevisiae Arabidopsis Rats, Inbred F344 Salmonella typhimurium Croton Cricetinae

Diseases7

Genomic Instability Micronuclei, Chromosome-Defective Ataxia Telangiectasia Chromosome Aberrations Neoplasms Cell Transformation, Neoplastic Cocarcinogenesis

Chemicals and Drugs126

Mutagens Tumor Suppressor Protein p53 Ataxia Telangiectasia Mutated Proteins Cell Cycle Proteins Methyl Methanesulfonate Tumor Suppressor Proteins Protein-Serine-Threonine Kinases DNA-Binding Proteins Nuclear Proteins CRADD Signaling Adaptor Protein Proto-Oncogene Proteins c-mdm2 Checkpoint Kinase 2 Doxorubicin Proto-Oncogene Proteins c-abl Cyclin-Dependent Kinase Inhibitor p21 Etoposide Hydroxyurea Mitomycin Histones Poly Adenosine Diphosphate Ribose Carcinogens Poly(ADP-ribose) Polymerases rhoB GTP-Binding Protein zeta-Crystallins Protein Kinases cdc25 Phosphatases Caspase 2 RNA, Small Interfering DNA Adducts Methylnitronitrosoguanidine Ubiquitin DNA Repair Enzymes Cisplatin Transcription Factors Alkylating Agents DNA Antimutagenic Agents Intracellular Signaling Peptides and Proteins Death Domain Receptor Signaling Adaptor Proteins Antibiotics, Antineoplastic Replication Protein A Antineoplastic Agents Cyclins Sirtuin 1 Apoptosis Regulatory Proteins SUMO-1 Protein E2F4 Transcription Factor Ubiquitin-Protein Ligases Saccharomyces cerevisiae Proteins RNA, Messenger Proto-Oncogene Proteins Histone Acetyltransferases Proteasome Endopeptidase Complex Chromatin DNA-Activated Protein Kinase Camptothecin Benzo(a)pyrene Proto-Oncogene Proteins c-bcl-2 Multiprotein Complexes Carcinogens, Environmental CDC2 Protein Kinase Serine Protein Kinase C-delta BRCA1 Protein Caspase 3 Mutant Proteins bcl-2-Associated X Protein Lysine Caspases Carrier Proteins DNA-(Apurinic or Apyrimidinic Site) Lyase Rad51 Recombinase Ribonucleotide Reductases I-kappa B Kinase Cyclin B Antigens, Nuclear Hydrogen Peroxide bcl-X Protein Reactive Oxygen Species Chromium Proliferating Cell Nuclear Antigen Bleomycin Mitogen-Activated Protein Kinases Enzyme Inhibitors Adaptor Proteins, Signal Transducing Aneugens DNA Primers Caffeine RNA-Binding Proteins Recombinant Fusion Proteins NF-kappa B Endonucleases DNA Helicases Chromates Protein Isoforms Cyclin-Dependent Kinases Retinoblastoma Protein p38 Mitogen-Activated Protein Kinases Chromosomal Proteins, Non-Histone Repressor Proteins Phosphoproteins Proteins Trans-Activators Protein Tyrosine Phosphatases E2F Transcription Factors Green Fluorescent Proteins 4-Nitroquinoline-1-oxide DNA, Complementary Neoplasm Proteins Epoxy Compounds Phosphoprotein Phosphatases Plant Extracts Phosphatidylinositol 3-Kinases JNK Mitogen-Activated Protein Kinases Pyrenes DNA, Neoplasm Polycyclic Hydrocarbons, Aromatic Benzene Hypoxanthine Phosphoribosyltransferase Aflatoxin B1 Ethylene Dibromide Recombinant Proteins Uranium Coal Tar Deoxyguanosine Phenolphthalein

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Mutagenicity Tests Comet Assay Transfection Models, Biological Blotting, Western Dose-Response Relationship, Radiation Carcinogenicity Tests Gene Knockdown Techniques Flow Cytometry Chromatin Immunoprecipitation Reverse Transcriptase Polymerase Chain Reaction Immunoblotting Gene Expression Profiling Immunoprecipitation Oligonucleotide Array Sequence Analysis Models, Genetic Mutagenesis, Site-Directed Microscopy, Fluorescence Fluorescent Antibody Technique Mitotic Index Immunohistochemistry Animal Testing Alternatives

Phenomena and Processes74

DNA Damage DNA Repair Ultraviolet Rays Radiation, Ionizing Apoptosis Gamma Rays Cell Cycle Genomic Instability Phosphorylation G2 Phase DNA Breaks, Double-Stranded Stress, Physiological Micronuclei, Chromosome-Defective Signal Transduction Cell Survival Mutation S Phase Protein Binding Genes, p53 DNA Replication Ubiquitination Cell Aging Cell Cycle Checkpoints Gene Expression Regulation DNA Adducts Transcriptional Activation Sister Chromatid Exchange Mitosis Sumoylation Active Transport, Cell Nucleus Oxidative Stress Transcription, Genetic Chromosome Aberrations Transfection RNA Interference Radiation Tolerance Enzyme Activation Down-Regulation Promoter Regions, Genetic G1 Phase Gene Expression Regulation, Neoplastic Cell Death Protein Processing, Post-Translational Base Sequence Dose-Response Relationship, Radiation Protein Transport Protein Structure, Tertiary Acetylation Cell Proliferation Cell Division Chromatin Amino Acid Sequence Dose-Response Relationship, Drug Time Factors Mutagenesis Up-Regulation Phenotype Gene Silencing Drug Resistance, Neoplasm Recombination, Genetic Gene Deletion Binding Sites Gene Expression Genes, Reporter Plasmids DNA Breaks Biotransformation Gene Expression Regulation, Fungal Amino Acid Motifs Gene Expression Regulation, Enzymologic Sequence Homology, Amino Acid Aging Protein Biosynthesis SOS Response (Genetics)

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care4

Ultraviolet Rays Dose-Response Relationship, Radiation Occupational Exposure Environmental Monitoring

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

DNA Damage Mutagens Tumor Suppressor Protein p53 Ataxia Telangiectasia Mutated Proteins Mutagenicity Tests Cell Cycle Proteins Methyl Methanesulfonate DNA Repair Ultraviolet Rays Radiation, Ionizing Apoptosis Tumor Suppressor Proteins Comet Assay Gamma Rays Cell Cycle Protein-Serine-Threonine Kinases DNA-Binding Proteins Cell Line, Tumor Nuclear Proteins CRADD Signaling Adaptor Protein Genomic Instability Phosphorylation Proto-Oncogene Proteins c-mdm2 Checkpoint Kinase 2 Doxorubicin G2 Phase Cell Line DNA Breaks, Double-Stranded Stress, Physiological Proto-Oncogene Proteins c-abl Micronuclei, Chromosome-Defective HCT116 Cells Signal Transduction Cyclin-Dependent Kinase Inhibitor p21 Cell Survival Mutation Fibroblasts S Phase Etoposide Hydroxyurea Mitomycin Histones Protein Binding Genes, p53 Poly Adenosine Diphosphate Ribose Carcinogens Poly(ADP-ribose) Polymerases DNA Replication rhoB GTP-Binding Protein zeta-Crystallins Cell Nucleus Protein Kinases HeLa Cells cdc25 Phosphatases Ubiquitination Cell Aging Caspase 2 Cell Cycle Checkpoints Gene Expression Regulation RNA, Small Interfering DNA Adducts Methylnitronitrosoguanidine Ubiquitin Cells, Cultured Transcriptional Activation Sister Chromatid Exchange DNA Repair Enzymes Mitosis Cisplatin Transcription Factors Sumoylation Alkylating Agents DNA Antimutagenic Agents Active Transport, Cell Nucleus Ataxia Telangiectasia Oxidative Stress Transcription, Genetic Intracellular Signaling Peptides and Proteins HEK293 Cells Death Domain Receptor Signaling Adaptor Proteins Molecular Sequence Data Chromosome Aberrations Transfection RNA Interference Radiation Tolerance Enzyme Activation Neoplasms Antibiotics, Antineoplastic Mice, Knockout Tumor Cells, Cultured Replication Protein A Antineoplastic Agents Cyclins Models, Biological Down-Regulation Promoter Regions, Genetic G1 Phase Sirtuin 1 Gene Expression Regulation, Neoplastic

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