• Defining the Epidemiology and Burden of Severe Respiratory Syncytial Virus Infection Among Infants and Children in Western Countries. (medscape.com)
  • Systematic review and meta-analysis of respiratory syncytial virus infection epidemiology in Latin America. (bvsalud.org)
  • Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. (cdc.gov)
  • Only 10% (4/40) persons as an at-risk population for severe RSV disease of patients with RSV infection who were readmitted within might guide prioritization strategies for RSV vaccines 30 days had a positive swab specimen for the same virus at and therapeutics as they become available. (cdc.gov)
  • The current lack of understanding of the mechanisms by which antibodies can protect against RSV infection and disease or, alternatively, contribute to disease severity, hampers the design of safe and effective vaccines against this virus. (ru.nl)
  • Clinicians should also talk to their patients about other vaccines available this fall to help prevent respiratory infections. (cdc.gov)
  • Both inactivated and modified live virus (MLV) BRSV vaccines are currently in use. (usask.ca)
  • Significant reductions in clinical disease, pulmonary pathology, and in trial 3, reduced virus shedding, were observed in calves vaccinated with the MLV or the FI BRSV vaccines. (usask.ca)
  • General Manager at Sanofi Vaccines UK and Ireland, Rebecca Catterick, and Baroness Margaret Ritchie discuss the impact of Respiratory Syncytial Virus (RSV) in our society, with ideas on how it can be mitigated through enhanced understanding and proactive approaches to treatment. (politicshome.com)
  • They usually identify the candidate virus in February, and flu vaccines aren't ready to go until July, August, or September for the next flu season. (pharmacytimes.com)
  • If there's a virus that infects the chicken population and eggs are contaminated [or] they're in short supply, we can develop these cell-cultured, synthetically manufactured vaccines to help with the total supply of flu vaccine out there in the United States. (pharmacytimes.com)
  • Vaccines or candidate vaccines used to prevent infection with RESPIRATORY SYNCYTIAL VIRUSES. (bvsalud.org)
  • Generally, these findings are neither specific to RSV infection nor predictive of the course or outcome, except for the observation that infants who have the additional findings of atelectasis or pneumonia may have a more severe disease course. (medscape.com)
  • PF-07960613 is under development for the prevention of respiratory syncytial virus infection and coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (pharmaceutical-technology.com)
  • For more than 20 years, effective prophylaxis against RSV infection has been achieved in the populations defined as being at high risk of severe or very severe disease due to RSV-clearly defined by the Sociedad Española de Neonatología (Spanish Society of Neonatology)-with the administration of a monoclonal antibody, palivizumab, which is very costly and has a short half-life. (analesdepediatria.org)
  • The development of a new monoclonal antibody with a longer half-life and of demonstrated efficacy and safety, nirsevimab, presents the opportunity to offer passive immunoprophylaxis universally to all healthy newborns to prevent these forms of disease in the period that they are most at risk of severe lower respiratory tract infection, chiefly in the first year of life. (analesdepediatria.org)
  • The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to notify clinicians and caregivers about increases in respiratory syncytial virus (RSV) activity across some parts of the Southeastern United States in recent weeks, suggesting a continued shift toward seasonal RSV trends observed prior to the COVID-19 pandemic. (cdc.gov)
  • Infants, young children, and older adults, especially those with chronic medical conditions, are at increased risk of severe disease from RSV infection. (cdc.gov)
  • Human respiratory syncytial virus (HRSV) is a major cause of lower respiratory tract disease in children and the elderly for which there is still no effective vaccine. (unina.it)
  • Because the extent to which protection demonstrated in rodent models will translate to humans is unclear, we have exploited the calf model of bovine RSV (BRSV) infection, which mimics HRSV disease in children more closely than do experimental models of unnatural laboratory hosts, to evaluate the safety and efficacy of the PanAd3-RSV vaccine. (unina.it)
  • We show that PanAd3-RSV alone and in combination with a modified vaccinia Ankara expressing the same HRSV antigens (MVA-RSV) induced neutralizing antibodies and cellular immunity in young seronegative calves and protected against upper and lower respiratory tract infection and pulmonary disease induced by heterologous BRSV challenge. (unina.it)
  • There was no evidence either of enhanced pulmonary pathology or of enhanced respiratory disease in vaccinated calves after BRSV challenge. (unina.it)
  • Respiratory syncytial virus (RSV), a common cause of winter outbreaks of acute respiratory disease, results in an estimated 90,000 hospitalizations and 4500 deaths each year from lower respiratory tract disease among infants and young children in the United States (1). (cdc.gov)
  • Editorial Note: During the RSV season, health-care providers should consider RSV as a cause of acute respiratory disease in both children and adults. (cdc.gov)
  • however, children of any age who have underlying cardiac or pulmonary disease or are immunocompromised are at risk for serious complications from this infection. (cdc.gov)
  • In adults, RSV usually causes upper respiratory tract symptoms but can cause lower respiratory tract disease, especially in elderly and in immunocompromised persons (4-6). (cdc.gov)
  • This review focuses on the burden of respiratory syncytial virus (RSV) infection in preterm infants with and without chronic lung disease (bronchopulmonary dysplasia, BPD). (openmicrobiologyjournal.com)
  • This model closely mirrors human RSV disease and affords a unique opportunity to study interepithelial cell interactions, cytokine responses from cells of different donors, and ciliary activity of live cells undergoing RSV infection. (nih.gov)
  • In August 2023, the US Food and Drug Administration (FDA) approved Abrysvo for use in pregnant individuals to prevent lower respiratory tract disease and severe lower respiratory tract disease caused by respiratory syncytial virus in infants from birth through six months of age. (wikipedia.org)
  • Respiratory syncytial virus vaccine is indicated for active immunization for the prevention of lower respiratory tract disease caused by respiratory syncytial virus in people 60 years of age and older. (wikipedia.org)
  • This vaccine induced a phenomenon that came to be known as vaccine-associated enhanced respiratory disease, in which children who had not previously been exposed to RSV and were subsequently vaccinated would develop a severe form of RSV disease if exposed to the virus itself, including fever, wheezing, and bronchopneumonia. (wikipedia.org)
  • RSV is a significant cause of severe respiratory disease in older adults, and it can cause disability and death. (pfizer.com)
  • We'll be talking about a deadly respiratory disease in wild chimpanzees. (cdc.gov)
  • We did this study, which was a study of rhinovirus C in chimpanzees, because we found ourselves in the middle of a severe outbreak of respiratory disease in a wild chimpanzee population in Uganda. (cdc.gov)
  • When you're looking at an egg-based vaccine, you start with a candidate virus that's determined by the FDA, the CDC [Centers for Disease Control and Prevention], and the WHO [World Health Organization]. (pharmacytimes.com)
  • Cystic fibrosis (CF) is a disease of exocrine gland function that involves multiple organ systems but chiefly results in chronic respiratory infections, pancreatic enzyme insufficiency, and associated complications in untreated patients. (medscape.com)
  • Circulation patterns of influenza and other respiratory viruses have been globally disrupted since the emergence of coronavirus disease (COVID-19) and the introduction of public health and social measures (PHSMs) aimed at reducing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. (who.int)
  • This literature review was therefore conducted to describe the burden of epidemic- and pandemic-prone acute respiratory infections (ARI) in the Region which may help in the development of evidence-based disease prevention and control policies. (who.int)
  • Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. (medscape.com)
  • RSV remains important viral etiological agent causing influenza-like illness and severe acute respiratory infections especially among infants in Morocco. (who.int)
  • A comparison of influenza and respiratory syncytial virus infections among infants admitted to hospital with acute respiratory infections. (docksci.com)
  • ABSTRACT Currently, respiratory syncytial virus (RSV) infection is identified in epidemiological studies by virus antigen or nucleic acid detection in combination with serology. (ox.ac.uk)
  • ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of mortality and morbidity in young infants, little was known on its circulation types and patterns in Morocco. (who.int)
  • Respiratory syncytial virus (RSV) (see the image below) is the leading cause of lower respiratory tract infections (LRTIs) in infants and young children. (medscape.com)
  • The respiratory tract is the parts of the body related to breathing (respiration). (msdmanuals.com)
  • that infects the respiratory tract. (msdmanuals.com)
  • RSV is one of many viruses that infect the respiratory tract. (msdmanuals.com)
  • Infection by respiratory syncytial virus (RSV) is the most common cause of hospital admission in infants aged less than 1 year in Spain, and severe forms requiring hospitalization in newborns and infants aged less than 3 months and lower respiratory tract infections in infants resulting a high volume of primary care and emergency department visits are particularly frequent. (analesdepediatria.org)
  • This response like the acute CTL response was found to be restricted to the lower respiratory tract. (microbiologyresearch.org)
  • Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections and hospitalization in infants under 1 year of age and there is currently no market-approved vaccine available. (ru.nl)
  • RSV is a prevalent viral infection that primarily impacts the respiratory tract, particularly in infants and young children. (gowellhealthtips.com)
  • Respiratory syncytial virus infection (RSV) , is a common respiratory virus that causes infections of the lungs and respiratory tract. (evidentic.com)
  • The typical clinical picture of lower respiratory tract infection is not different in term and preterm infants, but rates of apnoeas are significantly increased in preterms, ranging from 4.9 to 37.5 percent with decreasing rates observed in more recent studies. (openmicrobiologyjournal.com)
  • Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract infection in infants and children. (openmicrobiologyjournal.com)
  • In developed countries, there are well-defined high-risk groups, generally with chronic underlying disorders, in whom infection with RSV is more likely to progress into severe lower-respiratory-tract infections. (openmicrobiologyjournal.com)
  • When considering all countries, the largest pooled percentage RSV in low respiratory tract infection patients was found in the group between 0 and 11 months old, 41.5% (95% CI 32.0-51.4). (bvsalud.org)
  • Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in young children worldwide ( 1 - 3 ). (cdc.gov)
  • The studies evaluated showed that RSV lower respiratory tract infection is associated with an increased risk for subsequent development of asthma/recurrent wheezing, and that this association becomes progressively smaller with increasing age. (qxmd.com)
  • Respiratory syncytial virus (RSV), the most common viral pathogen causing acute lower respiratory tract infection among children under five years old worldwide, still lacks specific therapeutic drugs. (researchsquare.com)
  • So, we managed to retrieve Betty's body and do a thorough postmortem examination and collect samples from a number of different tissues, including her respiratory tract. (cdc.gov)
  • Overview of Viral Infections A virus is a microorganism, a tiny living organism. (msdmanuals.com)
  • Traditionally, antibody-mediated protection against viral infections is thought to be mediated by direct binding of antibodies to viral particles, resulting in virus neutralization. (ru.nl)
  • Background: Respiratory viral infections are one of the leading causes of need for emergency care and hospitalizations in asthmatic individuals, and airway-secreted cytokines are released within hours of viral infection to initiate these exacerbations. (cdc.gov)
  • Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993-2008. (cdc.gov)
  • Homeless persons experience with RSV infection were admitted to the intensive care unit higher rates of illness and death compared with the gen- (ICU), readmitted within 30 days, and received any anti- eral population, partly because of infectious diseases microbial drug compared with patients hospitalized with from lack of access to sanitation, crowding in shelters, influenza (Table 2). (cdc.gov)
  • Respiratory syncytial (sin-SISH-ul) virus (RSV) is a major cause of respiratory illness in children. (kidshealth.org)
  • Health care providers and public health officials use RSV circulation data to guide diagnostic testing and to time the administration of RSV immunoprophylaxis for populations at high risk for severe respiratory illness ( 6 ). (cdc.gov)
  • Respiratory syncytial virus (RSV) infection is a common respiratory illness caused by a virus. (cattco.org)
  • Little is known about the incidence of infection and type of illness caused by influenza viruses in infants. (docksci.com)
  • BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of respiratory illness worldwide, however, burden data on mother-infant pairs remain sparse in sub-Saharan Africa where HIV is prevalent. (itg.be)
  • METHODS: We enrolled pregnant women (≤20 weeks gestation) and followed them and their newborns weekly for up to 3-6 months post-partum, to document cases of acute respiratory illness (ARI). (itg.be)
  • CONCLUSION: HIV-infection may increase the risk of RSV illness among pregnant women. (itg.be)
  • We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and their infants in western Kenya.METHODS: We enrolled pregnant women (≤20 weeks gestation) and followed them and their newborns weekly for up to 3-6 months post-partum, to document cases of acute respiratory illness (ARI). (itg.be)
  • Observations of infections with and illness due to parainfluenza, mumps and respiratory syncytial viruses and Mycoplasma pneumoniae. (cdc.gov)
  • So, in practice, what happened is, when we realized that we were in the middle of a deadly respiratory outbreak, we put out a high alert for people to watch out for chimpanzees who might have succumbed to the illness. (cdc.gov)
  • When someone with RSV coughs or sneezes, a nearby person can get the virus by breathing in or touching droplets in the air that have the virus. (msdmanuals.com)
  • It spreads through droplets containing the virus when an infected person coughs or sneezes. (kidshealth.org)
  • RSV is an RNA virus, and transmission occurs primarily via respiratory droplets when a person coughs or sneezes, or through direct contact with a contaminated surface. (cdc.gov)
  • RSV is highly contagious and spreads through respiratory droplets, making crowded places, such as daycare centers and hospitals , potential hotspots for transmission. (gowellhealthtips.com)
  • RSV is extremely infectious and spreads by respiratory droplets, especially in crowded settings such as childcare centers and hospitals. (gowellhealthtips.com)
  • A3: RSV is highly contagious and spreads through respiratory droplets, making crowded places like daycare centers and hospitals potential hotspots for transmission. (gowellhealthtips.com)
  • Influenza spreads from person-to-person via respiratory droplets and requires close physical proximity for infection. (nature.com)
  • Maternal Respiratory Syncytial Virus Vaccination. (medscape.com)
  • Available at https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2023/09/maternal-respiratory-syncytial-virus-vaccination . (medscape.com)
  • Vaccination, particularly in high-risk individuals and the general public, is critical in reducing RSV infection and its repercussions. (gowellhealthtips.com)
  • RSV vaccination can help reduce RSV infection and its effects, especially in high-risk people and the general population. (gowellhealthtips.com)
  • The effect of vaccination on BRSV infection was investigated. (usask.ca)
  • Virus clearance in unvaccinated calves was independent of antibody and coincident with detection of BRSV specific cytotoxic cells, a response marginally accelerated by vaccination with MLV. (usask.ca)
  • Some eighty percent of such children (vs. 5% of virus-exposed controls) were hospitalized, and two children died of lethal lung inflammatory response during the first natural RSV infection after vaccination of RSV-naive infants. (wikipedia.org)
  • Influenza (Flu) Influenza, often called the flu, is a viral infection that affects your lungs and airways. (msdmanuals.com)
  • Virus antigen within the lungs was found to be restricted essentially to the alveolar regions. (microbiologyresearch.org)
  • In addition, infection induced rapid interferon production within the lungs which was accompanied by an equally rapid rise in pulmonary natural killer (NK) cell cytotoxic activity. (microbiologyresearch.org)
  • IgG was the first class of virus-specific immunoglobulin to be detected in the lungs of infected animals after experimental infection. (microbiologyresearch.org)
  • Immunoglobulin class specific antibody response in serum, spleen, lungs and bronchioal- veolar washings after primary and secondary Sendai virus infection of germ free mice. (microbiologyresearch.org)
  • RSV immune globulin intravenous (human) is available for prevention of serious RSV infections in some high-risk infants and children (9). (cdc.gov)
  • viii] Furthermore, a lack of data on the prevalence of the virus means that the burden of RSV in infants and children could be greater than estimates suggest. (politicshome.com)
  • A total of 4% (7/158) of adults given untreated chronic medical conditions, and higher rates a diagnosis of RSV infection died during hospitalization, of mental health issues and substance use ( 5 ). (cdc.gov)
  • We sought to determine whether increased hospital hospitalized with RSV infections versus those with in- readmission after hospitalization for RSV infection had fluenza in an urban medical center serving a region that other potential explanatory factors. (cdc.gov)
  • Palivizumab Prophylaxis in Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection. (medscape.com)
  • Respiratory and Enteric Viruses Br, Div of Viral and Rickettsial Diseases, National Center for Infectious Diseases, CDC. (cdc.gov)
  • This review provides a descriptive summary of the burden of acute respiratory diseases in the Region, but there still remains a lack of necessary data. (who.int)
  • In 2018, I got a small infection on my thumb that looked unusual, so I visited an emergency room. (cdc.gov)
  • Indication for immunoprophylaxis against severe RSV infection with nirsevimab, 2023-2024 season. (analesdepediatria.org)
  • Since September 2023, it is also indicated in the continental United States as seasonal protection during September through end of January for pregnant women as a one-time dose at 32 to 36 weeks gestation to prevent RSV-infection in infants younger than 6 months. (wikipedia.org)
  • What are the symptoms of respiratory syncytial virus (RSV) infections? (medlineplus.gov)
  • Healthcare personnel, childcare providers, and staff at long-term care facilities should stay home and not go to work when they have fever or symptoms of respiratory infection to reduce the spread of respiratory infections including RSV. (cdc.gov)
  • For protection against infection, young children mainly depend on their innate immune system and maternal antibodies. (ru.nl)
  • We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and their infants in western Kenya. (itg.be)
  • Chaves, Sandra S. / The impact of maternal HIV infection on the burden of respiratory syncytial virus among pregnant women and their infants, western Kenya . (itg.be)
  • Respiratory Syncytial Virus Infection (RSV): Trends and Surveillance. (medscape.com)
  • Nationally, the weekly percentage of positive detections reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS), a national laboratory-based surveillance network, has remained below the season onset threshold of polymerase chain reaction (PCR) test positivity of 3.0% for 2 consecutive weeks. (cdc.gov)
  • Our data show significant promise for the use of oral fluid alone in RSV infection surveillance. (ox.ac.uk)
  • RSV activity in the United States is monitored by the National Respiratory and Enteric Virus Surveillance System (NREVSS), a voluntary, laboratory-based system. (cdc.gov)
  • Reported by: National Respiratory and Enteric Virus Surveillance System collaborating laboratories. (cdc.gov)
  • Meanwhile, improvements are needed in infection surveillance and reporting to improve case identification and better characterize seasonal trends in infections along the Italian peninsula. (unibo.it)
  • This report uses a new statistical method that analyzes polymerase chain reaction laboratory detections reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS) to determine RSV seasonality nationally and by region for three recent seasons (2014-2017). (cdc.gov)
  • CDC reported RSV seasonality nationally, by U.S. Department of Health and Human Services (HHS) regions* and for the state of Florida, using a new statistical method that analyzes polymerase chain reaction (PCR) laboratory detections reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS) ( https://www.cdc.gov/surveillance/nrevss/index.html ). (cdc.gov)
  • We conducted a prospective study using sentinel-based influenza surveillance to detect RSV by real time PCR in patients with acute respiratory infections, enrolled during two seasons (2014/15, 2015/16). (who.int)
  • Further surveillance, is required to understand better the risk factors of RSV infections. (who.int)
  • Nous avons réalisé une étude prospective en recourant à la surveillance de la grippe basée sur des sites sentinelles dans le but de dépister le VRS grâce à la PCR en temps réel chez des patients souffrant d'infections respiratoires aiguës recrutés au cours de deux saisons (2014-2015 et 2015-2016). (who.int)
  • Une surveillance renforcée est indispensable pour mieux comprendre les facteurs de risque des infections à VRS. (who.int)
  • Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children. (cdc.gov)
  • Most cases of respiratory syncytial virus infection are mild and don't need medical treatment. (kidshealth.org)
  • RSV infection causes symptoms that vary from mild cold-like symptoms to severe difficulty breathing. (gowellhealthtips.com)
  • RSV infection presents a spectrum of symptoms, from mild cold-like manifestations to severe respiratory distress. (gowellhealthtips.com)
  • Usually, this virus causes mild, cold-like symptoms. (evidentic.com)
  • The proportion of positive RSV infection was higher in patients hospitalized with acute respiratory infection compared to those with mild symptoms in out-patient clinics. (who.int)
  • x] An RSV infection usually causes mild and self-limiting symptoms in children and adults which resolve within a couple of weeks. (politicshome.com)
  • Continuous research and global efforts are required to better understand RSV and develop comprehensive methods to lessen its impact, protect vulnerable people, and lower the overall burden of this respiratory virus. (gowellhealthtips.com)
  • Stakeholders and policymakers must develop access pathways once new agents are available to reduce the burden of infections and hospitalizations. (unibo.it)
  • Each year, 4-5 million children younger than 4 years acquire an RSV infection, and more than 125,000 are hospitalized annually in the United States because of this infection. (medscape.com)
  • The impact of RSV infection is not limited to only young children. (medscape.com)
  • Chest radiography is frequently obtained in children with severe RSV infection, but for the most part, typical findings are neither specific to RSV infection nor predictive of the course or outcome. (medscape.com)
  • Chest radiography is frequently obtained in children with severe RSV infection. (medscape.com)
  • People with young children should wash their hands a lot to keep from passing on the virus. (msdmanuals.com)
  • For five children sampled repeatedly from birth, antibody profiles in oral fluid quite consistently tracked those in paired sera, and RSV infections were detected by rising titers of antibodies of at least one Ig class. (ox.ac.uk)
  • Because of its yearly epidemics, Respiratory Syncytial Virus (RSV) is a serious public health concern, particularly among babies and young children. (gowellhealthtips.com)
  • This highly contagious seasonal virus is responsible for approximately 3 million hospitalizations and 120,000 deaths annually among children under the age of 5 years. (unibo.it)
  • Rapid diagnostic tests and confirmatory laboratory testing should be used for the differential diagnosis of respiratory pathogens in children. (unibo.it)
  • Human respiratory syncytial virus (RSV) is a common cause of respiratory infections in infants, young children, and elderly people. (authorea.com)
  • A survey of 604 Yemeni children younger than 2 years with acute respiratory infections identified respiratory syncytial virus (RSV) in 244 (40%), human metapneumovirus (HMPV) in 41 (7%) and RSV/HMPV coinfection in 25 (4%) children. (lstmed.ac.uk)
  • RSV infections occurred in younger children and were associated with more severe hypoxia than observed with HMPV. (lstmed.ac.uk)
  • Both influenza virus and RSV infections were diagnosed most frequently in children under the age of one year, and diagnosed more frequently in males than females. (docksci.com)
  • Both infections occurred more often, but were not more severe, in children from a conurbation than in those from 'rural' areas. (docksci.com)
  • In the present study, all the children under 5 years old with acute respiratory infections who were admitted to either Bristol Childrens' Hospital or Southmead Hospital during two winters from a circumscribed population were examined for respiratory virus infections as part of a collaborative study by the MRC Laboratory Working Party on RS Virus Infections. (docksci.com)
  • Patients It was intended to investigate all children under 5 years old admitted with acute respiratory infections. (docksci.com)
  • Of the 444 children tested in 1974/5, 61 (14 %) had proved infections with influenza A virus (26 resembling A/Port Chalmers/1/73, 16 resembling A/Scotland/840/74, 19 untyped, of which 16 were diagnosed by immunofluorescence only) and 124 (28 %) with RSV. (docksci.com)
  • Articles were included if they described original studies of confirmed RSV infection in children under 3 years of age, and had defined outcome variables. (qxmd.com)
  • So, they're a group of viruses that causes sniffles in children, maybe fevers, sore throats, cold-like symptoms, and usually don't cause that much harm in people, except under rare circumstances. (cdc.gov)
  • Respiratory syncytial virus, or RSV, is a common respiratory virus. (medlineplus.gov)
  • The desired vaccine would prevent lower respiratory infection from RSV in at-risk populations and if possible, be useful in other populations with less risk. (wikipedia.org)
  • Influenza activity levels were very low in all regions, lower than those recorded in 2017-2019, with less than 1% of laboratory samples testing positive for influenza virus. (who.int)
  • Sendai virus-induced cell mediated cytotoxicity in vitro: the role of viral glycoproteins in cell mediated cytotoxicity. (microbiologyresearch.org)
  • We found that 2, 4-DTBP-loaded micelles inhibited RSV infection in vitro and improved survival, lung pathology, and viral clearance in RSV-infected mice. (authorea.com)
  • To describe an in vitro model of human respiratory epithelium in primary cell culture linked with a computer microscope interface that allows evaluation and imaging of living RSV-infected respiratory epithelium. (nih.gov)
  • Systemic cell-mediated and antibody responses in infants with respiratory syncytial virus infections. (microbiologyresearch.org)
  • Vaccine efficacy, the significance of qualitative differences in antibody responses, and the correlates of immunity to BRSV infection, remain unexamined by a virulent experimental challenge. (usask.ca)
  • In trial 3, prechallenge serum antibody was not indicative of protection, but anamnestic serum and mucosal antibody responses had a low but significant negative predictive value for virus shedding and pulmonary pathology. (usask.ca)
  • Tests to check for complications in people with severe infection. (medlineplus.gov)
  • [ 1 ] Pediatric bacterial brain abscesses, epidural empyemas, and subdural empyemas, rare complications of respiratory infections and sinusitis, are often caused by Streptococcus species but might also be polymicrobial or caused by other genera, such as Staphylococcus . (medscape.com)
  • In contrast, rates of human rhinovirus infection were increased. (who.int)
  • Probable or confirmed ongoing case of viral respiratory infection (including COVID-19, influenza, rhinovirus, etc.) at the time of enrollment. (who.int)
  • PF-07960613 is under clinical development by Pfizer and currently in Phase II for Respiratory Syncytial Virus (RSV) Infections. (pharmaceutical-technology.com)
  • This includes supplemental oxygen when indicated, management of respiratory secretions and maintaining hydration. (medscape.com)
  • Secretions can be analyzed for virus in the laboratory by means of culture, antigen-revealing techniques, or polymerase chain reaction (PCR). (medscape.com)
  • In order to understand early events in the immune response to respiratory syncytial virus (RSV) infection, we studied the presence of various chemokines and cytokines in respiratory secretions of human infants with RSV infection. (utmb.edu)
  • Importantly, neutralization is only one of many mechanisms by which antibodies can interfere with viral infection. (ru.nl)
  • Emergence of a novel swine-origin influenza A (H1N1) virus in humans. (cdc.gov)
  • Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. (cdc.gov)
  • This section discusses pharmacological interventions, respiratory support, and other strategies aimed at alleviating the impact of RSV infection, particularly in severe cases. (gowellhealthtips.com)
  • Pulmonary A2 strain respiratory syncytial virus infection of BALB/c laboratory mice persisted for up to 7 days after initial infection with peak virus titres being recovered on day 4. (microbiologyresearch.org)
  • Clearance of persistent RSV infections in immunodeficient mice following transfer of primed T cells. (microbiologyresearch.org)
  • Primary respiratory syncytial virus infection in mice. (microbiologyresearch.org)
  • Methods: Sensitized BALB/c mice were challenged with aerosolized ovalbumin (OVA) to establish allergic inflammation, followed by RSV-A2 infection to yield four treatment groups: saline only (Saline), RSV-infected alone (RSV), OVA alone (OVA), and OVA-treated with RSV infection (OVA-RSV). (cdc.gov)
  • Results: While thymic stromal lymphopoietin (TSLP) and IL-33 were detected 6 h after RSV infection in the OVA-RSV mice, IL-23 protein was uniquely upregulated in RSV-infected mice alone. (cdc.gov)
  • OVA-RSV animals varied from RSV- or OVAtreated mice as they had increased lung eosinophils, neutrophils, group 2 innate lymphoid cells (ILC2) and group 3 innate lymphoid cells (ILC3) detectable as early as 6 h after RSV infection. (cdc.gov)
  • Perez-Yarza EG, Moreno A, Lazaro P, Mejias A, Ramilo O. The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature. (medscape.com)
  • Nebulizers with medicine that stops the wheezing in asthma (bronchodilators) don't help much with the wheezing in RSV infection. (msdmanuals.com)
  • however, RSV infections are associated with an increased long-term risk for recurring wheezing and the development of asthma. (unibo.it)
  • The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature. (qxmd.com)
  • The relation between early respiratory syncytial virus (RSV) infection and later emergence of episodes of wheezing/asthma remains a subject of debate. (qxmd.com)
  • We carried out a systematic review of studies of the association between RSV infection in the first 36 months of life and the subsequent development of asthma/bronchial hyperreactivity. (qxmd.com)
  • On the basis of this systematic review of the literature, it can be concluded that a significant association exists between RSV infection in childhood and the long-term development of subsequent episodes of recurrent wheezing or asthma. (qxmd.com)
  • In this review article, we aim to provide a comprehensive overview of the current knowledge on Fc-mediated antibody effector functions in the context of RSV infection, discuss their potential role in establishing the balance between protection and pathogenesis, and point out important gaps in our understanding of these processes. (ru.nl)
  • Influenza virus was isolated in monkey kidney or human embryo kidney cells, and RSV in bovine testis (Caul, Jacobs & Clarke, 1974), HEp-2, HeLa, or monkey kidney cells. (docksci.com)
  • The evolutionary dynamics of human influenza B virus. (cdc.gov)
  • And with those samples, we were able to use next- generation DNA sequencing methodologies to identify the virus, which, again, turned out to be this very common human virus that had never been seen in chimps before. (cdc.gov)
  • Since July 1992, a total of 100 clinical and public health laboratories in 47 states have participated in NREVSS and have reported weekly to CDC the number of specimens tested for RSV by the antigen-detection and virus-isolation methods and the number of positive results. (cdc.gov)
  • However, despite the wide clinical application of andrographolide in viral infection, there are few relevant research focusing on its effects and mechanism on RSV infection so far. (researchsquare.com)