• Here, we focused on the growth and metabolic interactions of the Oligo-Mouse-Microbiota (OMM 12 ) synthetic bacterial community, which is increasingly used as a model system in gut microbiome research. (nature.com)
  • It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. (lookformedical.com)
  • 0,05) en los animales tratados con plomo (T final: 0,66±0,36 A), al compararse con sapos control (C final: 0,91±0,50 A) al final del experimento. (scielo.org.ar)
  • These effects translated to rodents, where UA improved exercise capacity in two different mouse models of age-related decline of muscle function, as well as in young rats. (lsd1receptor.com)
  • Surprisingly, the mutant mice are healthy, with preserved respiratory chain capacity and normal exercise performance. (biomed.news)
  • Although SWCNT exposure did not modify the lipid profiles of these mice, it resulted in accelerated plaque formation in ApoE −/− mice fed an atherogenic diet. (nih.gov)
  • To gain mechanistic insight into the effect of dietary ω-3 LCPUFAs on CNV regression, researchers analyzed the lipid profiles of these mice and identified endogenous CYP-generated metabolites. (clinicalnews.org)
  • A single intrapharyngeal instillation of SWCNTs induced activation of heme oxygenase-1 (HO-1), a marker of oxidative insults, in lung, aorta, and heart tissue in HO-1 reporter transgenic mice. (nih.gov)
  • Because these modifications have been related to cardiovascular diseases, we evaluated whether repeated exposure to SWCNTs (20 μg/mouse once every other week for 8 weeks) stimulates the progression of atherosclerosis in ApoE −/− transgenic mice. (nih.gov)
  • 2007). Accelerated Aβ deposition in APPswe/PS1ΔE9 mice with hemizygous deletions of TTR (transthyretin) . (up.pt)
  • Furthermore, we found that C57BL/6 mice, exposed to SWCNT (10 and 40 μg/mouse), developed aortic mtDNA damage at 7, 28, and 60 days after exposure. (nih.gov)
  • Indeed, a contrast enhancement in the pancreas is observed when complex 1@SiO2-Py2PicNP and a glucose stimulus are administered in fasted healthy C57BL/6 mice at 7 T. (bvsalud.org)
  • In these studies we evaluated aortic mitochondrial alterations by oxidative stress assays, including quantitative polymerase chain reaction of mitochondrial (mt) DNA and plaque formation by morphometric analysis in mice exposed to SWCNTs. (nih.gov)
  • We examined the effects of 2,4-dinitrophenol (DNP), a recently described blocker of the aggregation and neurotoxicity of the beta-amyloid peptide, on neurite elongation of central neurons. (nih.gov)
  • BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice. (nih.gov)
  • Brs3 neurons in the mouse dorsomedial hypothalamus regulate body temperature, energy expenditure, and heart rate, but not food intake. (nih.gov)
  • It is perhaps best known for its influence on the formation, growth, survival, and development of neurons and for its role in mediating the beneficial cognitive effects associated with exercise . (foundmyfitness.com)
  • A study of mice exposed to moderate-to-high levels of arsine for 90 days revealed a significant decrease in hemoglobin and hematocrit along with an increase in mean corpuscular hemoglobins and mean corpuscular hemoglobin concentrations after 5 days of exposure. (medscape.com)
  • 2006). The LLNA is based upon characterization of chemicals comprising allergens of different potencies and non- induced proliferative responses in draining lymph nodes allergenic chemicals were evaluated for their ability to react with following topical exposure of mice to chemicals (Gerberick reduced glutathione (GSH) or with two synthetic peptides et al. (cdc.gov)
  • Neurite outgrowth is a critical event in neuronal development, formation, and remodeling of synapses, response to injury, and regeneration. (nih.gov)
  • BDNF is a member of a family of proteins called neurotrophins, which affect the formation of new neural synapses and help maintain existing synapses by binding to specific receptors located at the synaptic membrane. (foundmyfitness.com)
  • These findings provide a unique mechanism whereby specific CYP derived lipid metabolites regulate angiogenesis in a mouse model of AMD," said lead author Ryoji Yanai, M.D., Ph.D. (clinicalnews.org)
  • Plaque areas in the aortas, measured by the en face method, and in the brachiocephalic arteries, measured histopathologically, were significantly increased in the SWCNT-treated mice. (nih.gov)
  • Systemic immune-cell recruitment and adhesion-molecule regulation were significantly dampened in mice receiving ω-3s, thereby suppressing inflammation that is thought to exacerbate this disease. (clinicalnews.org)
  • To evaluate the effect of LCPUFAs on CNV development, researchers fed mice one of three experimental diets beginning two weeks before CNV induction by laser photocoagulation. (clinicalnews.org)
  • Cre Recombinase Driver Mice Reveal Lineage-Dependent and -Independent Expression of Brs3 in the Mouse Brain. (nih.gov)
  • The effects of housing density on mouse thermal physiology depend on sex and ambient temperature. (nih.gov)
  • Physiology and effects of nucleosides in mice lacking all four adenosine receptors. (nih.gov)
  • In vitro culture and light microscopic observation were employed to study its developmental process from spore germination to the formation of young gametophyte, as well as effects of light and temperature on its spore germination and protonemal development. (scielo.br)
  • DNP also promoted cAMP accumulation, increased tau level, neurite outgrowth, and neuronal differentiation in the mouse neuroblastoma cell line N2A. (nih.gov)
  • Other mechanisms of hemolysis may include the inhibition of catalase and the formation of reactive oxidative species (ROS), such as hydrogen peroxide, within the cell. (medscape.com)
  • Mouse Thermoregulation: Introducing the Concept of the Thermoneutral Point. (nih.gov)