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CefamandoleCephalosporinsMandelic AcidsCephalothinMicrobial Sensitivity TestsDrug Resistance, MicrobialAnti-Bacterial AgentsCefazolinCefoxitinPenicillin ResistanceEnterobacteriaceaeSpecies SpecificityCephapirinAmpicillinDrug Resistance, BacterialCephalosporinaseSequence Analysis, DNACefuroximeBacteriaEscherichia coliMethicillinStaphylococcusStaphylococcus aureusMutationPenicillinsMice, Inbred StrainsCulture MediaCefonicidGenes, BacterialCephaloridineBacterial Typing TechniquesRNA, Ribosomal, 16SDNA, BacterialEnterobacterCephamycinsMoxalactamDNA, RibosomalVirulenceCefoperazoneCarbenicillinbeta-LactamasesChloramphenicolProteusCefotaximeTobramycinVancomycinPhenotypePenicillinaseDrug ResistanceCephalexinStaphylococcus epidermidisBacterial ProteinsMolecular Sequence DataHaemophilus influenzaeSerotypingPolymerase Chain ReactionPremedicationStaphylococcal InfectionsGentamicinsPlasmidsStreptococcus pneumoniaePseudomonas aeruginosaStreptomycinErythromycinAminoglycosidesAmino Acid SequenceGenotypeAnti-Infective Agentsbeta-LactamsHypoprothrombinemiasPenicillin-Binding ProteinsOxacillinInsecticide ResistanceTetracyclineLactamsTime FactorsKineticsTicarcillinMuramoylpentapeptide CarboxypeptidaseHexosyltransferasesCeftriaxoneFluoroquinolonesPenicillin GHalf-LifeStreptococcusEscherichia coli InfectionsElectrophoresis, Gel, Pulsed-FieldMetronidazolePeptidyl TransferasesBacterial InfectionsBase CompositionDNA FingerprintingSarcinaMycobacterium tuberculosisRNA, BacterialGene Expression Regulation, BacterialCoagulaseGenetic VariationNucleic Acid HybridizationBacteroides fragilis
Serious Infections Caused by Susceptible StrainsVancomycin-resistantPenicillinase-resistantCefoxitinCephalosporinCefuroximeMethicillin-resistAntibiotic-resistantResistanceKlebsiellaBacterialClinicalPrevalentTransferableInfectionsDrug resistantColiESBLBroad-spectrumClinicallyGram-negativeAntibodiesAntibiotics
Serious Infections Caused by Susceptible Strains1
  • Cefamandole under brand name mandol is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms such as: lower respiratory infections, including pneumonia, caused by S. pneumoniae. (ncats.io)
Vancomycin-resistant5
  • Since 1989, a rapid increase in the incidence of infection and colonization with vancomycin-resistant enterococci (VRE) has been reported by U.S. hospitals. (cdc.gov)
  • This increase poses important problems, including a) the lack of available antimicrobial therapy for VRE infections, because most VRE are also resistant to drugs previously used to treat such infections (e.g., aminoglycosides and ampicillin), and b) the possibility that the vancomycin-resistant genes present in VRE can be transferred to other gram-positive microorganisms (e.g. (cdc.gov)
  • From 1989 through 1993, the percentage of nosocomial enterococcal infections reported to CDC's National Nosocomial Infections Surveillance (NNIS) system that were caused by vancomycin-resistant enterococci (VRE) increased from 0.3% to 7.9% (1). (cdc.gov)
  • INTRODUCTION From 1989 though 1993, the percentage of nosocomial enterococcal infections reported to the Centers for Disease Control and Prevention (CDC) National Nosocomial Infections Surveillance (NNIS) System that were caused by vancomycin-resistant enterococci (VRE) increased from 0.3% to 7.9%[1]. (cdc.gov)
  • Although vancomycin resistance in clinical strains of S. epidermidis or S. aureus has not been reported, vancomycin-resistant strains of S. haemolyticus have been isolated[21,22]. (cdc.gov)
Penicillinase-resistant2
  • not increased Management Lab, payments are French filtration Sales in photos good as public tofu penicillinase-resistant, making, applications to pad, and route. (onlinemedsupplies.com)
  • Oxacillin is a penicillinase-resistant β-lactam . (mdwiki.org)
Cefoxitin2
Cephalosporin2
  • ESBL producers are usually multiply drug resistant ( 5 , 30 ), but their cephalosporin and aztreonam resistance is not reliably detected by susceptibility tests ( 33 ). (asm.org)
  • Cefamandole (also known as cephamandole) is a broad-spectrum cephalosporin antibiotic. (ncats.io)
Cefuroxime1
  • cefuroxime and cefamandole) and third-generation ones (such as ceftazidime) tend to be more effective against gram-negative bacterial species that are resistant to the first-generation cephalosporins. (britannica.com)
Methicillin-resist1
  • This is vital for patient care, as advocated by Jarvis in stressing the importance of active detection and isolation to control methicillin-resistant Staphylococcus aureus and other resistant hospital-acquired pathogens ( 17 ). (asm.org)
Antibiotic-resistant2
  • Optimal use of microbiology laboratories is essential to combat the spread of multiply antibiotic-resistant pathogens. (asm.org)
  • However, with the introduction and widespread use of both oxacillin and methicillin, antibiotic-resistant strains called methicillin-resistant and oxacillin-resistant Staphylococcus aureus (MRSA/ORSA) have become increasingly prevalent worldwide. (mdwiki.org)
Resistance6
  • Thus, these drugs are active against Escherichia coli and Klebsiella and Proteus species (though several strains of these organisms have developed resistance). (britannica.com)
  • When the strain produces class A -lacta- cephamycinases, which confer resistance to expanded- mases, including TEM- or SHV-derived ESBLs, or CTX- spectrum cephalosporins (22,23), and no CTX-M-type - M-type enzymes, the color of a disk containing ben- lactamase producer has been isolated from animals. (cdc.gov)
  • cefamandole resistance transfer in bacterial strains from two newborn units. (liverpool.ac.uk)
  • transfer of cefamandole resistance was demonstrated from strains of citrobacter freundii as well as from individual strains of enterobacter cloacae, acinetobacter anitratus and klebsiella pneumoniae isolated from patients in two newborn units. (liverpool.ac.uk)
  • in citrobacter freundii, cefamandole resistance was transferred always with cephalotin resistance as well as with a tem-like beta lactamase (conferring resistance to ampicillin, carbenicillin and azlocillin). (liverpool.ac.uk)
  • This increase poses several problems, including a) the lack of available antimicrobials for therapy of infections caused by VRE, because most VRE are also resistant to multiple other drugs (e.g., aminoglycosides and ampicillin) previously used for the treatment of infections due to these organisms, and b) the possibility that the vancomycin resistance genes present in VRE may be transferred to other gram-positive microorganisms such as Staphylococcus aureus. (cdc.gov)
Klebsiella2
  • Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. (ajlmonline.org)
  • A 2006 report of the Infectious Diseases Society of America listed ESBL-producing Klebsiella pneumoniae and Escherichia coli among drug-resistant microbes for which new therapies are urgently needed. (ajlmonline.org)
Bacterial1
  • Like all beta-lactam antibiotics, cefamandole binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. (ncats.io)
Clinical1
  • In this study, after vaccination with the most widely used LaSota vaccine (genotype II), chickens with different hemagglutination inhibition (HI) antibody levels were challenged with heterologous virulent NDV strains of genotypes VII and IX to evaluate how antibody levels relate to clinical protection and infection or virus shedding. (bvsalud.org)
Prevalent1
  • In recent years, vaccines matched with the prevalent strains of genotype VII have been developed and are now commercially available. (bvsalud.org)
Transferable1
  • Escherichia coli transferable plasmids, and the gene was transferred to E. strains producing CTX-M-2 -lactamase, one of the CTX- coli CSH2 with a very high frequency (2 x 10-4 to 6 x 10-1 per donor cells) by conjugation. (cdc.gov)
Infections2
  • Infection control can prevent additional infections and the spread of resistant pathogens and thereby reduce the need to use antibiotics. (asm.org)
  • Members of the isoxazolyl penicillin family, which includes cloxacillin , dicloxacillin , and oxacillin, were synthesized to counter the increasing prevalence of infections caused by penicillin-resistant Staphylococcus aureus . (mdwiki.org)
Drug resistant1
  • alternative treatment of drug resistant falciparum malaria with particular reference to africa south of the sahara. (liverpool.ac.uk)
Coli1
  • n-alpha-palmitoyl-l-lysyl-l-lysine dihydrochloride ethyl ester (pll) at sublethal doses causes filamentous growth of e. coli strains except sfia mutants, which divide normally in its presence. (liverpool.ac.uk)
ESBL2
  • As for the disproportionately low isolation resistant bacteria in livestock is essential to suppress fur- rate of the TEM- or SHV-derived ESBL producers in ther dissemination of these bacteria into society at large. (cdc.gov)
  • ESBL producers would be rarely isolated and that metallo- strains producing extended-spectrum -lactamases -lactamases would be isolated often in Japan. (cdc.gov)
Broad-spectrum1
  • Several questions regarding the of strains producing broad-spectrum class A -lactamases origin and mode of proliferation of the CTX-M-type -lac- in Japan. (cdc.gov)
Clinically2
Gram-negative1
  • The absence of new, effective anti-gram-negative antibiotics makes infection control the most important countermeasure against multidrug-resistant gram-negative pathogens. (asm.org)
Antibodies1
  • This study was conducted on chicks hatched from hens vaccinated with a commercial genotype VII NDV-matched vaccine to investigate the correlation between hemagglutination inhibition (HI) antibody levels in chicks and hens and the decaying pattern of maternally derived HI antibodies, and to evaluate the protective efficacy of different levels of maternally derived HI antibodies against challenge with a virulent NDV strain of genotype VII based on survivability and virus shedding. (bvsalud.org)
Antibiotics1
  • Once, the isolate was sensitive to gentamicin and ceftriaxone but resistant to all available antibiotics tested on the other two occasions. (ajlmonline.org)